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The map label for this gene is ykuM [H]

Identifier: 116872412

GI number: 116872412

Start: 1014850

End: 1015728

Strand: Direct

Name: ykuM [H]

Synonym: lwe0994

Alternate gene names: 116872412

Gene position: 1014850-1015728 (Clockwise)

Preceding gene: 116872411

Following gene: 116872413

Centisome position: 36.06

GC content: 38.79

Gene sequence:

>879_bases
ATGATTGTAACGGAATATGAACTTCTTGTTTGTTTGGCGGAAGAACTAAATATGCGGAAAAGCGCAGAGAAACTGTTTTT
AAGTCAGCCTGCTTTATCACAGCGTTTGCAAACGATTGAAAGTAGATGGAATACCAAGATATTCATTCGTACGCAAAAAG
GATTGCTTCTTACACCAGAAGGAGAAGCCATTGTCCGTCACGCGTCTAGTGTCATTGAACGCGAACATACAATTCAAGAA
AAACTCGAAGCAATGGAAGGCGTCGTTCGGGGAACACTACGAATTGCGTGTGCTAGTGTAGTTGCGCAAATGTGGTTACC
GCGCGTATTAAAAGCATTTGCAAGTGCCTACCCTAATGTGCAAATTTCCCTTGTAACAGGCTGGAGCAGTGAAGTAACAC
AACAATTAGCAGCCGGAAATGTTCATATTGGTATTGTACGTGGGAATTCATCATGGAAAAGTGTCCAAAAACCGTTATTT
AACGATAAACTTGTTTTGGTTGATACGGAAATTACAAAGATTGAGGAAGTTTTCCAAACAAATCGTCCTTTTATCCAATT
TCGTAGTGATTCGAATTACTATCAAGTGATTCAAGATTACTGGCAAAGAAATTTCGGAAAAATGCCGCGTCAAGCCATGT
TAATGGATCAAATGGAAACGTCCAGACAAATGGCACTAAATGGCATTGGATTTGCGATATTACCAGAAGTGACGATGTTA
GGTTACACAGATAAAATCAATAAAATACCACTAACAGAAAAAGATGGCTCCATTCTTAGTAGAGAAACGAATTTGCTGAC
TTATGAGCAATCGCTTGGTTTACCTCAAGTGAAGGCGTTTTTAGAAATAACAGATAAATTCCTTGAACAAGTTAAATAG

Upstream 100 bases:

>100_bases
GTGTTGTCGATGCAGATCACCATTTTGAAGGAATTGTGACACGACGGGTTGTTTTAAAACAAGTCAATCGTTATATTCAC
TTACAAGTGGAGGAAAATAG

Downstream 100 bases:

>100_bases
CTATGGCAAAATAGAAAACAGAACGTATCGGAAGGGGACTAAAATTCATGGAACAAATGGATGCACACCAAATTATTTCT
TTTATTCAAAATAGCAAAAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MIVTEYELLVCLAEELNMRKSAEKLFLSQPALSQRLQTIESRWNTKIFIRTQKGLLLTPEGEAIVRHASSVIEREHTIQE
KLEAMEGVVRGTLRIACASVVAQMWLPRVLKAFASAYPNVQISLVTGWSSEVTQQLAAGNVHIGIVRGNSSWKSVQKPLF
NDKLVLVDTEITKIEEVFQTNRPFIQFRSDSNYYQVIQDYWQRNFGKMPRQAMLMDQMETSRQMALNGIGFAILPEVTML
GYTDKINKIPLTEKDGSILSRETNLLTYEQSLGLPQVKAFLEITDKFLEQVK

Sequences:

>Translated_292_residues
MIVTEYELLVCLAEELNMRKSAEKLFLSQPALSQRLQTIESRWNTKIFIRTQKGLLLTPEGEAIVRHASSVIEREHTIQE
KLEAMEGVVRGTLRIACASVVAQMWLPRVLKAFASAYPNVQISLVTGWSSEVTQQLAAGNVHIGIVRGNSSWKSVQKPLF
NDKLVLVDTEITKIEEVFQTNRPFIQFRSDSNYYQVIQDYWQRNFGKMPRQAMLMDQMETSRQMALNGIGFAILPEVTML
GYTDKINKIPLTEKDGSILSRETNLLTYEQSLGLPQVKAFLEITDKFLEQVK
>Mature_292_residues
MIVTEYELLVCLAEELNMRKSAEKLFLSQPALSQRLQTIESRWNTKIFIRTQKGLLLTPEGEAIVRHASSVIEREHTIQE
KLEAMEGVVRGTLRIACASVVAQMWLPRVLKAFASAYPNVQISLVTGWSSEVTQQLAAGNVHIGIVRGNSSWKSVQKPLF
NDKLVLVDTEITKIEEVFQTNRPFIQFRSDSNYYQVIQDYWQRNFGKMPRQAMLMDQMETSRQMALNGIGFAILPEVTML
GYTDKINKIPLTEKDGSILSRETNLLTYEQSLGLPQVKAFLEITDKFLEQVK

Specific function: Could Be The Regulator Of The Abg Operon. [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=137, Percent_Identity=27.7372262773723, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787530, Length=133, Percent_Identity=30.0751879699248, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787806, Length=263, Percent_Identity=21.6730038022814, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790208, Length=293, Percent_Identity=21.8430034129693, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI145693105, Length=159, Percent_Identity=25.1572327044025, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790399, Length=170, Percent_Identity=25.2941176470588, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788296, Length=133, Percent_Identity=29.3233082706767, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1786401, Length=158, Percent_Identity=29.746835443038, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI87081904, Length=139, Percent_Identity=29.4964028776978, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788887, Length=248, Percent_Identity=23.3870967741935, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1789173, Length=144, Percent_Identity=26.3888888888889, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33288; Mature: 33288

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVTEYELLVCLAEELNMRKSAEKLFLSQPALSQRLQTIESRWNTKIFIRTQKGLLLTPE
CEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCEEECCC
GEAIVRHASSVIEREHTIQEKLEAMEGVVRGTLRIACASVVAQMWLPRVLKAFASAYPNV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
QISLVTGWSSEVTQQLAAGNVHIGIVRGNSSWKSVQKPLFNDKLVLVDTEITKIEEVFQT
EEEEEECCCHHHHHHHHCCCEEEEEEECCCCHHHHHCCCCCCCEEEEECHHHHHHHHHHC
NRPFIQFRSDSNYYQVIQDYWQRNFGKMPRQAMLMDQMETSRQMALNGIGFAILPEVTML
CCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
GYTDKINKIPLTEKDGSILSRETNLLTYEQSLGLPQVKAFLEITDKFLEQVK
CCCCCCCCCCCCCCCCCHHHCCCCEEEEHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIVTEYELLVCLAEELNMRKSAEKLFLSQPALSQRLQTIESRWNTKIFIRTQKGLLLTPE
CEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCEEECCC
GEAIVRHASSVIEREHTIQEKLEAMEGVVRGTLRIACASVVAQMWLPRVLKAFASAYPNV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
QISLVTGWSSEVTQQLAAGNVHIGIVRGNSSWKSVQKPLFNDKLVLVDTEITKIEEVFQT
EEEEEECCCHHHHHHHHCCCEEEEEEECCCCHHHHHCCCCCCCEEEEECHHHHHHHHHHC
NRPFIQFRSDSNYYQVIQDYWQRNFGKMPRQAMLMDQMETSRQMALNGIGFAILPEVTML
CCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
GYTDKINKIPLTEKDGSILSRETNLLTYEQSLGLPQVKAFLEITDKFLEQVK
CCCCCCCCCCCCCCCCCHHHCCCCEEEEHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]