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The map label for this gene is dapH

Identifier: 116872413

GI number: 116872413

Start: 1015776

End: 1016486

Strand: Direct

Name: dapH

Synonym: lwe0995

Alternate gene names: 116872413

Gene position: 1015776-1016486 (Clockwise)

Preceding gene: 116872412

Following gene: 116872414

Centisome position: 36.1

GC content: 39.66

Gene sequence:

>711_bases
ATGGAACAAATGGATGCACACCAAATTATTTCTTTTATTCAAAATAGCAAAAAAGCAACACCTGTAAAAGTTTACCTAAA
AGGGGACTTAGAAAAAATTGATTTTCCAAGTGATGTAAAAACATTCATTACAGGAAACGCGGGAACTATTTTTGGAGAAT
GGGCTGTAGTTGAGCCATTATTAGAAGCAAATAAAGCGAATATTGAAGATTACGTAATCGAAAATGATCGTCGTAACTCG
GCTATTCCTTTGTTAGATATGAAAAACATTAACGCACGCATCGAGCCTGGTGCAGTTATTCGCGACCAAGTAACTATCGG
TGACAATGCTGTAATTATGATGGGTGCAAGTATCAATATCGGTTCAGTAATCGGTGATGGAACAATGATTGATATGAATG
TTGTTCTTGGTGGCCGTGCAACTGTAGGTAAAAACTGCCATATTGGTGCAGGTTCTGTCCTTGCTGGCGTAGTTGAACCG
CCATCCGCACAACCAGTTATTGTAGAAGATAATGTGGTTGTAGGTGCGAATGTCGTTGTTCTAGAAGGTGTACGTATTGG
AGAGGGCGCGGTTGTTGCAGCTGGAGCTATCGTTACAAAAGATGTAGCCCCTGGAACTGTTGTAGCTGGAATCCCAGCTC
GTGAACTAAAAAAATTAGATGCAAAAACAGCTTCTAAAACAGAAATTATGCAAGAACTTCGTCAACTTTAA

Upstream 100 bases:

>100_bases
AAGTGAAGGCGTTTTTAGAAATAACAGATAAATTCCTTGAACAAGTTAAATAGCTATGGCAAAATAGAAAACAGAACGTA
TCGGAAGGGGACTAAAATTC

Downstream 100 bases:

>100_bases
AACCTAAGGGAACTGTTTCGTCTTTTGGCGGAACAGTCCTTTTTAAAAGGAGAGAATTGTCATGCTAAATGAATTTATAG
CCATTCGTCGTGATTTACAT

Product: 2,3,4,5-tetrahydropyridine-2-carboxylate N- succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-acetyltransferase; THP acetyltransferase; Tetrahydropicolinate acetylase

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MEQMDAHQIISFIQNSKKATPVKVYLKGDLEKIDFPSDVKTFITGNAGTIFGEWAVVEPLLEANKANIEDYVIENDRRNS
AIPLLDMKNINARIEPGAVIRDQVTIGDNAVIMMGASINIGSVIGDGTMIDMNVVLGGRATVGKNCHIGAGSVLAGVVEP
PSAQPVIVEDNVVVGANVVVLEGVRIGEGAVVAAGAIVTKDVAPGTVVAGIPARELKKLDAKTASKTEIMQELRQL

Sequences:

>Translated_236_residues
MEQMDAHQIISFIQNSKKATPVKVYLKGDLEKIDFPSDVKTFITGNAGTIFGEWAVVEPLLEANKANIEDYVIENDRRNS
AIPLLDMKNINARIEPGAVIRDQVTIGDNAVIMMGASINIGSVIGDGTMIDMNVVLGGRATVGKNCHIGAGSVLAGVVEP
PSAQPVIVEDNVVVGANVVVLEGVRIGEGAVVAAGAIVTKDVAPGTVVAGIPARELKKLDAKTASKTEIMQELRQL
>Mature_236_residues
MEQMDAHQIISFIQNSKKATPVKVYLKGDLEKIDFPSDVKTFITGNAGTIFGEWAVVEPLLEANKANIEDYVIENDRRNS
AIPLLDMKNINARIEPGAVIRDQVTIGDNAVIMMGASINIGSVIGDGTMIDMNVVLGGRATVGKNCHIGAGSVLAGVVEP
PSAQPVIVEDNVVVGANVVVLEGVRIGEGAVVAAGAIVTKDVAPGTVVAGIPARELKKLDAKTASKTEIMQELRQL

Specific function: Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. DapH subfamily

Homologues:

Organism=Escherichia coli, GI1786362, Length=171, Percent_Identity=32.7485380116959, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786537, Length=132, Percent_Identity=29.5454545454545, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPH_LISIN (Q92D11)

Other databases:

- EMBL:   AL596167
- PIR:   AI1558
- RefSeq:   NP_470347.1
- HSSP:   P50870
- ProteinModelPortal:   Q92D11
- SMR:   Q92D11
- GeneID:   1129528
- GenomeReviews:   AL592022_GR
- KEGG:   lin:lin1010
- GenoList:   LIN1010
- HOGENOM:   HBG704071
- OMA:   KNAVIMM
- ProtClustDB:   CLSK809346
- BioCyc:   LINN272626:LIN1010-MONOMER
- HAMAP:   MF_01691
- InterPro:   IPR013710
- InterPro:   IPR018357
- InterPro:   IPR019873
- InterPro:   IPR011004
- TIGRFAMs:   TIGR03532

Pfam domain/function: PF08503 DapD_N; SSF51161 Trimer_LpxA_like

EC number: =2.3.1.89

Molecular weight: Translated: 24849; Mature: 24849

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQMDAHQIISFIQNSKKATPVKVYLKGDLEKIDFPSDVKTFITGNAGTIFGEWAVVEPL
CCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCEEEECHHHHHHH
LEANKANIEDYVIENDRRNSAIPLLDMKNINARIEPGAVIRDQVTIGDNAVIMMGASINI
HHCCCCCCCEEEEECCCCCCCCCEEEECCCCCEECCCCEEEEEEEECCCEEEEEECCCCC
GSVIGDGTMIDMNVVLGGRATVGKNCHIGAGSVLAGVVEPPSAQPVIVEDNVVVGANVVV
CEEECCCEEEEEEEEECCCEECCCCCCCCCCHHEEEEECCCCCCCEEEECCEEECCCEEE
LEGVRIGEGAVVAAGAIVTKDVAPGTVVAGIPARELKKLDAKTASKTEIMQELRQL
EECEEECCCCEEEECEEEECCCCCCEEEECCCHHHHHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MEQMDAHQIISFIQNSKKATPVKVYLKGDLEKIDFPSDVKTFITGNAGTIFGEWAVVEPL
CCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCEEEECHHHHHHH
LEANKANIEDYVIENDRRNSAIPLLDMKNINARIEPGAVIRDQVTIGDNAVIMMGASINI
HHCCCCCCCEEEEECCCCCCCCCEEEECCCCCEECCCCEEEEEEEECCCEEEEEECCCCC
GSVIGDGTMIDMNVVLGGRATVGKNCHIGAGSVLAGVVEPPSAQPVIVEDNVVVGANVVV
CEEECCCEEEEEEEEECCCEECCCCCCCCCCHHEEEEECCCCCCCEEEECCEEECCCEEE
LEGVRIGEGAVVAAGAIVTKDVAPGTVVAGIPARELKKLDAKTASKTEIMQELRQL
EECEEECCCCEEEECEEEECCCCCCEEEECCCHHHHHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669