Click here to switch to the map view.

The map label for this gene is rsbR [H]

Identifier: 116872291

GI number: 116872291

Start: 904476

End: 905312

Strand: Direct

Name: rsbR [H]

Synonym: lwe0871

Alternate gene names: 116872291

Gene position: 904476-905312 (Clockwise)

Preceding gene: 116872290

Following gene: 116872292

Centisome position: 32.14

GC content: 35.72

Gene sequence:

>837_bases
ATGTATAAAGATTTTGCAAACTTCATCCGTACAAATAAAACAGACCTACTAAATAACTGGATGAATGAAATGGAGAAACA
AACAGATCAACTTATAAATGATATTGCTAAAGAACCAATGTATGAAGAAACTAGCATTGAATTTGTTGATTTAATCGTAC
TTAACATCACAGATACTGACTCTAAATTTAACGAGAAACTAGATGATTTTGCAGAAAAAGTGGTCCACTTAGGTTGGCCA
ATTCATTTTGTCACCACAGGCCTACGTGTTTTCGGGCTTTTAGTATATACAGCAATGAGAGATGAAGATTTATTCTTAAA
AAGAGAAGAAAAACCAGAAGATGATGCCTATTATCGCTTTGAAACATGGCTTTCCTCTATGTATAACAAAGTGGTCACTG
CCTACGCAGATACGTGGGAAAAGACAGTTTCTATCCAAAAAATCGCTTTACAGGAATTATCAGCACCACTGTTACCAATA
TTTGAAAAAATTTCTGTAATGCCTTTAATTGGAACGATTGACACAGAAAGAGCTAAGTTAATCATAGAAAACTTACTAAT
AGGTGTAGTAAAAAATCGGTCAGAAGTGGTTTTGATTGATATTACGGGAGTTCCTGTAGTTGATACAATGGTTGCGCATC
ATATTATTCAAGCTTCAGAAGCAGTGAGACTTGTTGGTTGTCAAGCAATGCTTGTAGGAATTAGACCAGAAATAGCGCAA
ACCATCGTTAACTTAGGAATAGAATTAGATCAAATTATCACGACCAACACGATGAAAAAAGGCATGGAGCGTGCGCTAGC
CTTGACGAACAGAGAGATAGTAGAAAAAGAGGGGTGA

Upstream 100 bases:

>100_bases
TAAATTTGTTTCTAATGTCTTTTTTTGAAAAGTAGTTAATCCAATTACAGAAAAAAAGAGAAAATTTTGTTACTAGTGGA
GAAAGGTTGGAAAATAACTG

Downstream 100 bases:

>100_bases
ATACTGTGGGGATACCAATCTTAAAGTTAGGTGAATGTTTATTAATTTCTATCCAGAGTGAATTAGATGATCATACTGCG
GTAGAATTCCAAGAAGATTT

Product: RsbR protein

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MYKDFANFIRTNKTDLLNNWMNEMEKQTDQLINDIAKEPMYEETSIEFVDLIVLNITDTDSKFNEKLDDFAEKVVHLGWP
IHFVTTGLRVFGLLVYTAMRDEDLFLKREEKPEDDAYYRFETWLSSMYNKVVTAYADTWEKTVSIQKIALQELSAPLLPI
FEKISVMPLIGTIDTERAKLIIENLLIGVVKNRSEVVLIDITGVPVVDTMVAHHIIQASEAVRLVGCQAMLVGIRPEIAQ
TIVNLGIELDQIITTNTMKKGMERALALTNREIVEKEG

Sequences:

>Translated_278_residues
MYKDFANFIRTNKTDLLNNWMNEMEKQTDQLINDIAKEPMYEETSIEFVDLIVLNITDTDSKFNEKLDDFAEKVVHLGWP
IHFVTTGLRVFGLLVYTAMRDEDLFLKREEKPEDDAYYRFETWLSSMYNKVVTAYADTWEKTVSIQKIALQELSAPLLPI
FEKISVMPLIGTIDTERAKLIIENLLIGVVKNRSEVVLIDITGVPVVDTMVAHHIIQASEAVRLVGCQAMLVGIRPEIAQ
TIVNLGIELDQIITTNTMKKGMERALALTNREIVEKEG
>Mature_278_residues
MYKDFANFIRTNKTDLLNNWMNEMEKQTDQLINDIAKEPMYEETSIEFVDLIVLNITDTDSKFNEKLDDFAEKVVHLGWP
IHFVTTGLRVFGLLVYTAMRDEDLFLKREEKPEDDAYYRFETWLSSMYNKVVTAYADTWEKTVSIQKIALQELSAPLLPI
FEKISVMPLIGTIDTERAKLIIENLLIGVVKNRSEVVLIDITGVPVVDTMVAHHIIQASEAVRLVGCQAMLVGIRPEIAQ
TIVNLGIELDQIITTNTMKKGMERALALTNREIVEKEG

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 31772; Mature: 31772

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKDFANFIRTNKTDLLNNWMNEMEKQTDQLINDIAKEPMYEETSIEFVDLIVLNITDTD
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCC
SKFNEKLDDFAEKVVHLGWPIHFVTTGLRVFGLLVYTAMRDEDLFLKREEKPEDDAYYRF
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCCCCCHHHHH
ETWLSSMYNKVVTAYADTWEKTVSIQKIALQELSAPLLPIFEKISVMPLIGTIDTERAKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHH
IIENLLIGVVKNRSEVVLIDITGVPVVDTMVAHHIIQASEAVRLVGCQAMLVGIRPEIAQ
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
TIVNLGIELDQIITTNTMKKGMERALALTNREIVEKEG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYKDFANFIRTNKTDLLNNWMNEMEKQTDQLINDIAKEPMYEETSIEFVDLIVLNITDTD
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCC
SKFNEKLDDFAEKVVHLGWPIHFVTTGLRVFGLLVYTAMRDEDLFLKREEKPEDDAYYRF
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCCCCCHHHHH
ETWLSSMYNKVVTAYADTWEKTVSIQKIALQELSAPLLPIFEKISVMPLIGTIDTERAKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHH
IIENLLIGVVKNRSEVVLIDITGVPVVDTMVAHHIIQASEAVRLVGCQAMLVGIRPEIAQ
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
TIVNLGIELDQIITTNTMKKGMERALALTNREIVEKEG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]