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The map label for this gene is rsbS [H]

Identifier: 116872292

GI number: 116872292

Start: 905318

End: 905674

Strand: Direct

Name: rsbS [H]

Synonym: lwe0872

Alternate gene names: 116872292

Gene position: 905318-905674 (Clockwise)

Preceding gene: 116872291

Following gene: 116872293

Centisome position: 32.17

GC content: 37.25

Gene sequence:

>357_bases
GTGGGGATACCAATCTTAAAGTTAGGTGAATGTTTATTAATTTCTATCCAGAGTGAATTAGATGATCATACTGCGGTAGA
ATTCCAAGAAGATTTACTTGCAAAGATTCATGAAACGTCGGCCAGAGGAGTAGTTATTGATATTACTTCCATCGATTTTA
TTGATTCATTTATTGCAAAAATTCTTGGAGATGTAGTAAGTATGTCTAAACTTATGGGTGCAAAAGTGGTTGTAACTGGG
ATACAGCCAGCAGTTGCTATTACACTAATTGAGCTCGGAATTACATTTAGTGGAGTGCTTTCGGCAATGGACCTTGAAAG
CGGTCTGGAAAAACTTAAACAGGAATTGGGGGAATGA

Upstream 100 bases:

>100_bases
AATTAGATCAAATTATCACGACCAACACGATGAAAAAAGGCATGGAGCGTGCGCTAGCCTTGACGAACAGAGAGATAGTA
GAAAAAGAGGGGTGAATACT

Downstream 100 bases:

>100_bases
ACATGACATTCCAATCCTGTGTAAAGATAATTAATGAGTGGGACATTGTGGCTGCAAGACAGCTTGGTAGAAAAATATCC
AAAGAAATTGGTTTTGGAAC

Product: RsbS protein

Products: NA

Alternate protein names: Stressosome protein rsbS [H]

Number of amino acids: Translated: 118; Mature: 117

Protein sequence:

>118_residues
MGIPILKLGECLLISIQSELDDHTAVEFQEDLLAKIHETSARGVVIDITSIDFIDSFIAKILGDVVSMSKLMGAKVVVTG
IQPAVAITLIELGITFSGVLSAMDLESGLEKLKQELGE

Sequences:

>Translated_118_residues
MGIPILKLGECLLISIQSELDDHTAVEFQEDLLAKIHETSARGVVIDITSIDFIDSFIAKILGDVVSMSKLMGAKVVVTG
IQPAVAITLIELGITFSGVLSAMDLESGLEKLKQELGE
>Mature_117_residues
GIPILKLGECLLISIQSELDDHTAVEFQEDLLAKIHETSARGVVIDITSIDFIDSFIAKILGDVVSMSKLMGAKVVVTGI
QPAVAITLIELGITFSGVLSAMDLESGLEKLKQELGE

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 12597; Mature: 12466

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIPILKLGECLLISIQSELDDHTAVEFQEDLLAKIHETSARGVVIDITSIDFIDSFIAK
CCCCHHHHCHHHEEHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHH
ILGDVVSMSKLMGAKVVVTGIQPAVAITLIELGITFSGVLSAMDLESGLEKLKQELGE
HHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GIPILKLGECLLISIQSELDDHTAVEFQEDLLAKIHETSARGVVIDITSIDFIDSFIAK
CCCHHHHCHHHEEHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHH
ILGDVVSMSKLMGAKVVVTGIQPAVAITLIELGITFSGVLSAMDLESGLEKLKQELGE
HHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 8824586; 8682789 [H]