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The map label for this gene is sugE [H]

Identifier: 116872267

GI number: 116872267

Start: 879840

End: 880160

Strand: Direct

Name: sugE [H]

Synonym: lwe0847

Alternate gene names: 116872267

Gene position: 879840-880160 (Clockwise)

Preceding gene: 116872266

Following gene: 116872268

Centisome position: 31.27

GC content: 37.69

Gene sequence:

>321_bases
ATGGATTGGATATTTTTACTTGTAGCAGGTCTCTGTGAAATGGTGTTCGTTGTCATGCTAAAATTATCTGATGGCTTTAA
ACGATTCGGATATGCGACACTTACAATTATTTTTATGGCAGCGAGTTTCTTTTTACTTTCACATGCTCTTAAAACGATAC
CGATTGGGACGGGTTATGCGATTTGGACCGGAATTGGCGCAGTAGGTAGCGTGTTACTAGGTATGATTGTGTTTAAAGAG
CGTAAAAGTGTTGGGAAATTGCTTTTTATTACGATGATAATTGCAGGCGTAGTTGGTTTAAAATTAACATCTGGCGTTTA
A

Upstream 100 bases:

>100_bases
TTTCTTTTTGGAAAATTGTGTCGCTTCTTGTATTACTATCAGGAATTATCGGTTTGAAATTAGTAGATGGTAACGATGCT
AAAAAGGAGGCTAAATAACA

Downstream 100 bases:

>100_bases
TAAAGTAGGTTGAAAAAGTCCTTTTTGGAATAAGTGGGTACGTTTCTTATTTAAAAAAGAAGATTTTTTCAACCTATTTT
TTAGTTATGTCTTTTCATCT

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 106; Mature: 106

Protein sequence:

>106_residues
MDWIFLLVAGLCEMVFVVMLKLSDGFKRFGYATLTIIFMAASFFLLSHALKTIPIGTGYAIWTGIGAVGSVLLGMIVFKE
RKSVGKLLFITMIIAGVVGLKLTSGV

Sequences:

>Translated_106_residues
MDWIFLLVAGLCEMVFVVMLKLSDGFKRFGYATLTIIFMAASFFLLSHALKTIPIGTGYAIWTGIGAVGSVLLGMIVFKE
RKSVGKLLFITMIIAGVVGLKLTSGV
>Mature_106_residues
MDWIFLLVAGLCEMVFVVMLKLSDGFKRFGYATLTIIFMAASFFLLSHALKTIPIGTGYAIWTGIGAVGSVLLGMIVFKE
RKSVGKLLFITMIIAGVVGLKLTSGV

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=104, Percent_Identity=42.3076923076923, Blast_Score=93, Evalue=4e-21,
Organism=Escherichia coli, GI1786755, Length=103, Percent_Identity=37.8640776699029, Blast_Score=60, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11437; Mature: 11437

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWIFLLVAGLCEMVFVVMLKLSDGFKRFGYATLTIIFMAASFFLLSHALKTIPIGTGYA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
IWTGIGAVGSVLLGMIVFKERKSVGKLLFITMIIAGVVGLKLTSGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDWIFLLVAGLCEMVFVVMLKLSDGFKRFGYATLTIIFMAASFFLLSHALKTIPIGTGYA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
IWTGIGAVGSVLLGMIVFKERKSVGKLLFITMIIAGVVGLKLTSGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]