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The map label for this gene is sugE [H]

Identifier: 116872266

GI number: 116872266

Start: 879496

End: 879837

Strand: Direct

Name: sugE [H]

Synonym: lwe0846

Alternate gene names: 116872266

Gene position: 879496-879837 (Clockwise)

Preceding gene: 116872265

Following gene: 116872267

Centisome position: 31.25

GC content: 35.09

Gene sequence:

>342_bases
ATGGCTTGGTTTTATTTAATTATGGCAGGATTATCAGAAATTGTGTGGGCTTTTGGACTGAAAGAATCGCATGGTTTTAC
TATATTAGGTTGGAGTCTTTTAACGATAGCATTTTTGATTGTTAGTTTTGGTTTATTTTCAATGTCGATGAAGGCAATTC
CGATTGGGACAGCTTATGCGGTTTTTACCGGAATTGGAGCTGCTGGAACAGCCATTATTGGAATGATTTTTCTTTCAGAA
GGTATTTCTTTTTGGAAAATTGTGTCGCTTCTTGTATTACTATCAGGAATTATCGGTTTGAAATTAGTAGATGGTAACGA
TGCTAAAAAGGAGGCTAAATAA

Upstream 100 bases:

>100_bases
GTGGAACATGGGATTTATGATGAGGCAGAATTTGAATCGCGAAGGACATCTGCTTGGGAAGTGCTAGCAAGTTTACTAGA
ATGAAGTGGAGGTAAAGGAA

Downstream 100 bases:

>100_bases
CAATGGATTGGATATTTTTACTTGTAGCAGGTCTCTGTGAAATGGTGTTCGTTGTCATGCTAAAATTATCTGATGGCTTT
AAACGATTCGGATATGCGAC

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 112

Protein sequence:

>113_residues
MAWFYLIMAGLSEIVWAFGLKESHGFTILGWSLLTIAFLIVSFGLFSMSMKAIPIGTAYAVFTGIGAAGTAIIGMIFLSE
GISFWKIVSLLVLLSGIIGLKLVDGNDAKKEAK

Sequences:

>Translated_113_residues
MAWFYLIMAGLSEIVWAFGLKESHGFTILGWSLLTIAFLIVSFGLFSMSMKAIPIGTAYAVFTGIGAAGTAIIGMIFLSE
GISFWKIVSLLVLLSGIIGLKLVDGNDAKKEAK
>Mature_112_residues
AWFYLIMAGLSEIVWAFGLKESHGFTILGWSLLTIAFLIVSFGLFSMSMKAIPIGTAYAVFTGIGAAGTAIIGMIFLSEG
ISFWKIVSLLVLLSGIIGLKLVDGNDAKKEAK

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=102, Percent_Identity=50.9803921568627, Blast_Score=100, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 12080; Mature: 11949

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWFYLIMAGLSEIVWAFGLKESHGFTILGWSLLTIAFLIVSFGLFSMSMKAIPIGTAYA
CHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
VFTGIGAAGTAIIGMIFLSEGISFWKIVSLLVLLSGIIGLKLVDGNDAKKEAK
HHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCC
>Mature Secondary Structure 
AWFYLIMAGLSEIVWAFGLKESHGFTILGWSLLTIAFLIVSFGLFSMSMKAIPIGTAYA
HHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
VFTGIGAAGTAIIGMIFLSEGISFWKIVSLLVLLSGIIGLKLVDGNDAKKEAK
HHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]