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The map label for this gene is acoR [H]

Identifier: 116689863

GI number: 116689863

Start: 2046611

End: 2048530

Strand: Direct

Name: acoR [H]

Synonym: Bcen2424_1842

Alternate gene names: 116689863

Gene position: 2046611-2048530 (Clockwise)

Preceding gene: 116689856

Following gene: 116689866

Centisome position: 58.74

GC content: 71.98

Gene sequence:

>1920_bases
ATGCCCTACGCCGTCCCCCAGGCCCAGCACGCCGATCGTGTCCTCGGCGCGCTCGCCGGACGCCTGCCCGCGCCGGCGGA
TTCCGCGCGTCTCGTGTCGTCGTGGCAACGATCGCTGGAGCGCTACCGTCTCGACCCCGCTTCGTCGATCGGCCCGCGCG
TGCTGACCGCGGCCGAACTGCGCGAAGTGCGCGACAAGGAGGAAGCCTTCCTGCGCGCGTCGGGCCAGTGCCTGACGCGG
CTGCACGACATGATCCGCGTCGCCGATTACTGCGTGATGCTGACCGACGCGCACGGCGTGACGATCGACTACCGGATCGA
CCGCGAACGCCGCAACGACTTCCGTCACGCGGGGCTGCACATCGGCTCGTGCTGGTCGGAAAGCGAGGAAGGAACCTGCG
GTGTCGCGAGCGTGCTGACCGATCTCGCGCCGATCACCGTGCACAAGACCGATCACTTTCGCGCCGCGTTCACGACGCTC
ACCTGCAGCGCGGCGCCGATCTTCTCGCCGGGCGGCGAGTTGATCGGCGTGCTCGACGCGTCGGCCGTGCATTCGCCCGA
CGGCCGCGACAGCCAGCGCCTCGTCTATCAGCTCGTGCGGCAGAGCGCGGCGCTGATCGAGGACGGCTACTTCGTGCACA
GCACCGCGCAGCACTGGATATTGTTCGGGCATCCGAACCGTCACTACGTCGAGGCGCAACCGGAGTGGCTGATCGCGTTC
GACGAATGCGGCAACATCGTCGCCGCGAACCGGCACGCGCGCGATGCGCTGCCGGCGCTGCGCGAGCCGCGCCATATCGA
CGAGATCTTCGACGCGACCGAGATGCCGCTGCGCGATGCGGCGCGGCTCGATGCCATCGTCGCGCTGCGGGTGCGCGCGA
CCGGCGCACCGCTCTACGCGCGGCTGCGCGCGCCGCTACGACGCGCCGGCCGTGAACCGGCCGCTGCATCGCGCCGCCCG
GGCACCACCGCGCCGCGTCACGTCGGCGCGCTGACGCCGTTCCTGCACAGCAGCGACGCGCGCATCGCGCAACAGGCCGA
ACTCGCGCTGCGCGTCGCGAGCAAGCGGCTGCCTATCCTCGTGCTCGGCGAAACCGGCGCGGGCAAGGAAGTGTTCGCCC
GCGCGATCCACGACGCCGGCGCACGGCGCGCGCGGCCGTTCATCGCCGTCAACTGCGGCGCGCTGCCGGAAGCGCTGATC
GAGAGCGAACTGTTCGGTTATGCGGCCGGCGCGTTCACCGGCGCACGCAAGCACGGCGCGCGCGGCAAGATCGCGCTCGC
CGACGGCGGCACGCTGTTTCTCGATGAAATCGGCGACATGCCGCTCGCGCTGCAGACGCGCCTGTTGCGCGTCCTGGCCG
ACGGCGAGGTCGTGCCGCTCGGCAGCGATACGCCCGTGCGCGTCGATCTCGACGTGATCTGCGCGACGCACCGCGATCTC
GGGCGGATGGTGGCCGACGGCACGTTCCGCGAAGACCTGTACTACCGGCTGAGCGGCGCGACGTTCGACCTGCCGCCGCT
GCGCGAACGCGCGGACGTGCGCGACGTGATCGCCGCCGTGTTCGCCGAGGAAGCGCAAGCGACCGGCCACGTGCTCACGC
TCGACGCGACGCTCGCCGAACAGCTCGCCGCGTATCCATGGCCGGGCAACGTGCGGCAACTGCGCAACGTGCTGCGCTAT
GCGTGCGCGGTGTGCGACGCCGCGCGCGTGACGCGGCGCGACCTGCCGACCGACCTCGCCGCGCAACTCGGCGGCGCGCC
GGCGGGCGCGCTGCCCGACGACGAACGCAGCCGCATCGTCGCCGCGCTCACCATGCACCGCTGGCGGCCCGACGCGGCCG
CCCGGGCGCTCGGCATGTCGCGCGCGACGCTGTACCGGCGCATCGCGAAGTACCGGATCGTCGCGCCGCACCGCGCGTGA

Upstream 100 bases:

>100_bases
CCGTCTCACGCGCGCCGCGTGCTGCGATGCAATGTGATCCGCAGGACCGGATGTGCTACAAGAACAGCGACATCCCCGCC
GTACGGAACCGGAGCCGACC

Downstream 100 bases:

>100_bases
CGCACGGGCGCATGCCTGGTCATGCGGGCTGCCCGGCCGCTTCGTTCGGGTGGTCCGTCACGCCGGCCGCTTCGTCGCGC
CGCGTGAACACCTCGTGCGC

Product: Fis family GAF modulated sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 639; Mature: 638

Protein sequence:

>639_residues
MPYAVPQAQHADRVLGALAGRLPAPADSARLVSSWQRSLERYRLDPASSIGPRVLTAAELREVRDKEEAFLRASGQCLTR
LHDMIRVADYCVMLTDAHGVTIDYRIDRERRNDFRHAGLHIGSCWSESEEGTCGVASVLTDLAPITVHKTDHFRAAFTTL
TCSAAPIFSPGGELIGVLDASAVHSPDGRDSQRLVYQLVRQSAALIEDGYFVHSTAQHWILFGHPNRHYVEAQPEWLIAF
DECGNIVAANRHARDALPALREPRHIDEIFDATEMPLRDAARLDAIVALRVRATGAPLYARLRAPLRRAGREPAAASRRP
GTTAPRHVGALTPFLHSSDARIAQQAELALRVASKRLPILVLGETGAGKEVFARAIHDAGARRARPFIAVNCGALPEALI
ESELFGYAAGAFTGARKHGARGKIALADGGTLFLDEIGDMPLALQTRLLRVLADGEVVPLGSDTPVRVDLDVICATHRDL
GRMVADGTFREDLYYRLSGATFDLPPLRERADVRDVIAAVFAEEAQATGHVLTLDATLAEQLAAYPWPGNVRQLRNVLRY
ACAVCDAARVTRRDLPTDLAAQLGGAPAGALPDDERSRIVAALTMHRWRPDAAARALGMSRATLYRRIAKYRIVAPHRA

Sequences:

>Translated_639_residues
MPYAVPQAQHADRVLGALAGRLPAPADSARLVSSWQRSLERYRLDPASSIGPRVLTAAELREVRDKEEAFLRASGQCLTR
LHDMIRVADYCVMLTDAHGVTIDYRIDRERRNDFRHAGLHIGSCWSESEEGTCGVASVLTDLAPITVHKTDHFRAAFTTL
TCSAAPIFSPGGELIGVLDASAVHSPDGRDSQRLVYQLVRQSAALIEDGYFVHSTAQHWILFGHPNRHYVEAQPEWLIAF
DECGNIVAANRHARDALPALREPRHIDEIFDATEMPLRDAARLDAIVALRVRATGAPLYARLRAPLRRAGREPAAASRRP
GTTAPRHVGALTPFLHSSDARIAQQAELALRVASKRLPILVLGETGAGKEVFARAIHDAGARRARPFIAVNCGALPEALI
ESELFGYAAGAFTGARKHGARGKIALADGGTLFLDEIGDMPLALQTRLLRVLADGEVVPLGSDTPVRVDLDVICATHRDL
GRMVADGTFREDLYYRLSGATFDLPPLRERADVRDVIAAVFAEEAQATGHVLTLDATLAEQLAAYPWPGNVRQLRNVLRY
ACAVCDAARVTRRDLPTDLAAQLGGAPAGALPDDERSRIVAALTMHRWRPDAAARALGMSRATLYRRIAKYRIVAPHRA
>Mature_638_residues
PYAVPQAQHADRVLGALAGRLPAPADSARLVSSWQRSLERYRLDPASSIGPRVLTAAELREVRDKEEAFLRASGQCLTRL
HDMIRVADYCVMLTDAHGVTIDYRIDRERRNDFRHAGLHIGSCWSESEEGTCGVASVLTDLAPITVHKTDHFRAAFTTLT
CSAAPIFSPGGELIGVLDASAVHSPDGRDSQRLVYQLVRQSAALIEDGYFVHSTAQHWILFGHPNRHYVEAQPEWLIAFD
ECGNIVAANRHARDALPALREPRHIDEIFDATEMPLRDAARLDAIVALRVRATGAPLYARLRAPLRRAGREPAAASRRPG
TTAPRHVGALTPFLHSSDARIAQQAELALRVASKRLPILVLGETGAGKEVFARAIHDAGARRARPFIAVNCGALPEALIE
SELFGYAAGAFTGARKHGARGKIALADGGTLFLDEIGDMPLALQTRLLRVLADGEVVPLGSDTPVRVDLDVICATHRDLG
RMVADGTFREDLYYRLSGATFDLPPLRERADVRDVIAAVFAEEAQATGHVLTLDATLAEQLAAYPWPGNVRQLRNVLRYA
CAVCDAARVTRRDLPTDLAAQLGGAPAGALPDDERSRIVAALTMHRWRPDAAARALGMSRATLYRRIAKYRIVAPHRA

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=317, Percent_Identity=41.0094637223975, Blast_Score=233, Evalue=3e-62,
Organism=Escherichia coli, GI1788905, Length=299, Percent_Identity=40.4682274247492, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1788550, Length=297, Percent_Identity=39.3939393939394, Blast_Score=206, Evalue=5e-54,
Organism=Escherichia coli, GI87082117, Length=313, Percent_Identity=41.85303514377, Blast_Score=206, Evalue=5e-54,
Organism=Escherichia coli, GI1790299, Length=314, Percent_Identity=39.8089171974522, Blast_Score=199, Evalue=6e-52,
Organism=Escherichia coli, GI1789087, Length=301, Percent_Identity=40.8637873754153, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1790437, Length=293, Percent_Identity=40.9556313993174, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1786524, Length=293, Percent_Identity=44.0273037542662, Blast_Score=195, Evalue=8e-51,
Organism=Escherichia coli, GI87082152, Length=279, Percent_Identity=42.6523297491039, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI1787583, Length=327, Percent_Identity=35.7798165137615, Blast_Score=176, Evalue=4e-45,
Organism=Escherichia coli, GI87081872, Length=206, Percent_Identity=45.6310679611651, Blast_Score=171, Evalue=2e-43,
Organism=Escherichia coli, GI87081858, Length=560, Percent_Identity=24.1071428571429, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1789828, Length=242, Percent_Identity=37.1900826446281, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 69686; Mature: 69555

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYAVPQAQHADRVLGALAGRLPAPADSARLVSSWQRSLERYRLDPASSIGPRVLTAAEL
CCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
REVRDKEEAFLRASGQCLTRLHDMIRVADYCVMLTDAHGVTIDYRIDRERRNDFRHAGLH
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEECCCCEEEEEEECHHHHHHHHHHCCE
IGSCWSESEEGTCGVASVLTDLAPITVHKTDHFRAAFTTLTCSAAPIFSPGGELIGVLDA
EECCCCCCCCCCCHHHHHHHHCCCEEEECCCCHHHHHHEEEECCCCCCCCCCCEEEEEEH
SAVHSPDGRDSQRLVYQLVRQSAALIEDGYFVHSTAQHWILFGHPNRHYVEAQPEWLIAF
HHCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCCCEEECCCCEEEEE
DECGNIVAANRHARDALPALREPRHIDEIFDATEMPLRDAARLDAIVALRVRATGAPLYA
CCCCCEEECCCCHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHEEEEEEECCCCCHHH
RLRAPLRRAGREPAAASRRPGTTAPRHVGALTPFLHSSDARIAQQAELALRVASKRLPIL
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCHHHCCCCHHHHHHHHHHHHHHHCCCCEE
VLGETGAGKEVFARAIHDAGARRARPFIAVNCGALPEALIESELFGYAAGAFTGARKHGA
EEECCCCCHHHHHHHHHHCCHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCC
RGKIALADGGTLFLDEIGDMPLALQTRLLRVLADGEVVPLGSDTPVRVDLDVICATHRDL
CCEEEEECCCEEEEHHHCCCCHHHHHHHHHHHCCCCEEECCCCCCEEEEEEEEECCHHHH
GRMVADGTFREDLYYRLSGATFDLPPLRERADVRDVIAAVFAEEAQATGHVLTLDATLAE
HHHHHCCCHHHHHHEEECCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHH
QLAAYPWPGNVRQLRNVLRYACAVCDAARVTRRDLPTDLAAQLGGAPAGALPDDERSRIV
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCHHHHHH
AALTMHRWRPDAAARALGMSRATLYRRIAKYRIVAPHRA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCC
>Mature Secondary Structure 
PYAVPQAQHADRVLGALAGRLPAPADSARLVSSWQRSLERYRLDPASSIGPRVLTAAEL
CCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
REVRDKEEAFLRASGQCLTRLHDMIRVADYCVMLTDAHGVTIDYRIDRERRNDFRHAGLH
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEECCCCEEEEEEECHHHHHHHHHHCCE
IGSCWSESEEGTCGVASVLTDLAPITVHKTDHFRAAFTTLTCSAAPIFSPGGELIGVLDA
EECCCCCCCCCCCHHHHHHHHCCCEEEECCCCHHHHHHEEEECCCCCCCCCCCEEEEEEH
SAVHSPDGRDSQRLVYQLVRQSAALIEDGYFVHSTAQHWILFGHPNRHYVEAQPEWLIAF
HHCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCCCEEECCCCEEEEE
DECGNIVAANRHARDALPALREPRHIDEIFDATEMPLRDAARLDAIVALRVRATGAPLYA
CCCCCEEECCCCHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHEEEEEEECCCCCHHH
RLRAPLRRAGREPAAASRRPGTTAPRHVGALTPFLHSSDARIAQQAELALRVASKRLPIL
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCHHHCCCCHHHHHHHHHHHHHHHCCCCEE
VLGETGAGKEVFARAIHDAGARRARPFIAVNCGALPEALIESELFGYAAGAFTGARKHGA
EEECCCCCHHHHHHHHHHCCHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCC
RGKIALADGGTLFLDEIGDMPLALQTRLLRVLADGEVVPLGSDTPVRVDLDVICATHRDL
CCEEEEECCCEEEEHHHCCCCHHHHHHHHHHHCCCCEEECCCCCCEEEEEEEEECCHHHH
GRMVADGTFREDLYYRLSGATFDLPPLRERADVRDVIAAVFAEEAQATGHVLTLDATLAE
HHHHHCCCHHHHHHEEECCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHH
QLAAYPWPGNVRQLRNVLRYACAVCDAARVTRRDLPTDLAAQLGGAPAGALPDDERSRIV
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCHHHHHH
AALTMHRWRPDAAARALGMSRATLYRRIAKYRIVAPHRA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]