The gene/protein map for NC_008542 is currently unavailable.
Definition Burkholderia cenocepacia HI2424 chromosome 1, complete sequence.
Accession NC_008542
Length 3,483,902

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The map label for this gene is phbB [H]

Identifier: 116689810

GI number: 116689810

Start: 1985762

End: 1986502

Strand: Reverse

Name: phbB [H]

Synonym: Bcen2424_1789

Alternate gene names: 116689810

Gene position: 1986502-1985762 (Counterclockwise)

Preceding gene: 116689811

Following gene: 116689809

Centisome position: 57.02

GC content: 63.16

Gene sequence:

>741_bases
ATGTCTCAGCGAATTGCGTACGTAACGGGCGGGATGGGCGGCATCGGCACCAGCATCTGCCAGCGCCTGTCGAAAGACGG
CTTCAAGGTGGTTGCAGGTTGTGGCCCGAACTCGCCGCGCCGGGTGAAATGGCTCGAGGACCAGAAGGCGCTCGGGTACG
ACTTCATCGCGTCGGAAGGCAACGTCGGCGACTGGGACTCGACCAAGGAAGCGTTCGACAAGGTCAAGGCCGAAGTCGGC
GAGATCGACGTGCTGGTCAACAACGCGGGCATCACGCGCGACGTCGTGTTCCGCAAGATGACGCATGAAGACTGGACCGC
CGTGATCGACACCAACCTGACGAGCCTGTTCAACGTCACGAAGCAGGTGATCGACGGGATGGTCGAACGTGGCTGGGGCC
GCATCATCAACATTTCGTCGGTGAACGGCCAGAAGGGGCAATTCGGCCAGACGAACTACTCGACCGCGAAGGCCGGTATT
CACGGCTTCACGATGTCGCTCGCGCAGGAAGTCGCGACGAAGGGCGTGACGGTCAACACCGTGTCGCCGGGCTACATCGG
TACCGACATGGTGAAGGCAATCCGCCCCGACGTGCTCGAGAAGATCGTCGCGACGATCCCGGTGCGGCGTCTCGGCGGTC
CCGAGGAAATCGGCTCGATCGTCGCGTGGCTCGCGTCGAACGATTCCGGCTTCGCGACGGGCGCCGACTTCTCGCTGAAC
GGCGGCCTGCACATGGGCTGA

Upstream 100 bases:

>100_bases
AACCGAATCCGTGCGTCGGCCGATTGCGGCTTCGGCCGGCGTCACGTGAAGTCAGAGGGGGCTCCGGCAGCTCTCGAAAC
CAAAAAATGGAGTGAGATTT

Downstream 100 bases:

>100_bases
GCGTCCGGGCTGCGCCGGCCGGGTGGCCGCGCAGCCGGGCGTTTTCCGAAGGCCCCCGCCTCCCGGATTCGGGCGGCGGG
GATTCGTCACTTGCGCTACG

Product: acetyacetyl-CoA reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MSQRIAYVTGGMGGIGTSICQRLSKDGFKVVAGCGPNSPRRVKWLEDQKALGYDFIASEGNVGDWDSTKEAFDKVKAEVG
EIDVLVNNAGITRDVVFRKMTHEDWTAVIDTNLTSLFNVTKQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGI
HGFTMSLAQEVATKGVTVNTVSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGGPEEIGSIVAWLASNDSGFATGADFSLN
GGLHMG

Sequences:

>Translated_246_residues
MSQRIAYVTGGMGGIGTSICQRLSKDGFKVVAGCGPNSPRRVKWLEDQKALGYDFIASEGNVGDWDSTKEAFDKVKAEVG
EIDVLVNNAGITRDVVFRKMTHEDWTAVIDTNLTSLFNVTKQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGI
HGFTMSLAQEVATKGVTVNTVSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGGPEEIGSIVAWLASNDSGFATGADFSLN
GGLHMG
>Mature_245_residues
SQRIAYVTGGMGGIGTSICQRLSKDGFKVVAGCGPNSPRRVKWLEDQKALGYDFIASEGNVGDWDSTKEAFDKVKAEVGE
IDVLVNNAGITRDVVFRKMTHEDWTAVIDTNLTSLFNVTKQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIH
GFTMSLAQEVATKGVTVNTVSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGGPEEIGSIVAWLASNDSGFATGADFSLNG
GLHMG

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=36.3636363636364, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=32.1138211382114, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI4758504, Length=254, Percent_Identity=32.2834645669291, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI4504505, Length=250, Percent_Identity=32, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=29.5546558704453, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI83715985, Length=254, Percent_Identity=30.7086614173228, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=29.6, Blast_Score=91, Evalue=6e-19,
Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=27.710843373494, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=27.5303643724696, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=27.6, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=28.0487804878049, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI109715829, Length=239, Percent_Identity=26.3598326359833, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI66933014, Length=187, Percent_Identity=29.4117647058824, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI7705855, Length=209, Percent_Identity=31.5789473684211, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI59889578, Length=208, Percent_Identity=29.8076923076923, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI31542939, Length=206, Percent_Identity=31.0679611650485, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI7706318, Length=201, Percent_Identity=28.3582089552239, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI40548397, Length=207, Percent_Identity=29.4685990338164, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI214010158, Length=207, Percent_Identity=29.4685990338164, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI214010156, Length=207, Percent_Identity=29.4685990338164, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI22758144, Length=207, Percent_Identity=29.4685990338164, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI33667109, Length=198, Percent_Identity=30.3030303030303, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI150247226, Length=191, Percent_Identity=29.3193717277487, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI22507405, Length=187, Percent_Identity=29.9465240641711, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI7657478, Length=192, Percent_Identity=27.6041666666667, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI226371731, Length=193, Percent_Identity=27.979274611399, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI19743808, Length=193, Percent_Identity=28.4974093264249, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI210032112, Length=143, Percent_Identity=27.972027972028, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI20149619, Length=200, Percent_Identity=26.5, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=42.741935483871, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=35.8565737051793, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1790717, Length=240, Percent_Identity=31.6666666666667, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1789208, Length=242, Percent_Identity=30.1652892561983, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1788459, Length=254, Percent_Identity=28.3464566929134, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=31.6, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=28.1632653061224, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787820, Length=185, Percent_Identity=34.5945945945946, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI2367365, Length=242, Percent_Identity=29.7520661157025, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1786812, Length=204, Percent_Identity=27.4509803921569, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787905, Length=240, Percent_Identity=27.0833333333333, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=25.7936507936508, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=25, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786701, Length=222, Percent_Identity=25.6756756756757, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=41.3934426229508, Blast_Score=167, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=37.3983739837398, Blast_Score=160, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=30, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=32.2834645669291, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17568967, Length=217, Percent_Identity=34.1013824884793, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=29.3172690763052, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI115534694, Length=240, Percent_Identity=28.75, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=28.3400809716599, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=27.6, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI193203115, Length=233, Percent_Identity=29.1845493562232, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193203117, Length=240, Percent_Identity=28.75, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=260, Percent_Identity=29.6153846153846, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=28, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=28.6852589641434, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17561272, Length=196, Percent_Identity=28.0612244897959, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=251, Percent_Identity=28.2868525896414, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=29.1044776119403, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=255, Percent_Identity=29.4117647058824, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=246, Percent_Identity=26.8292682926829, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=269, Percent_Identity=26.7657992565056, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=252, Percent_Identity=28.1746031746032, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=28.9473684210526, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=256, Percent_Identity=28.125, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=28.1481481481481, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=27.0676691729323, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=251, Percent_Identity=27.8884462151394, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=247, Percent_Identity=25.1012145748988, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=254, Percent_Identity=27.1653543307087, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=278, Percent_Identity=26.2589928057554, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=138, Percent_Identity=29.7101449275362, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=26.6917293233083, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=212, Percent_Identity=24.0566037735849, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=212, Percent_Identity=24.0566037735849, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=184, Percent_Identity=25.5434782608696, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=254, Percent_Identity=32.2834645669291, Blast_Score=110, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6324126, Length=255, Percent_Identity=26.2745098039216, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323882, Length=201, Percent_Identity=27.8606965174129, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=35.3174603174603, Blast_Score=138, Evalue=3e-33,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=33.201581027668, Blast_Score=117, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=29.7619047619048, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=32.8125, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=27.6, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21357041, Length=174, Percent_Identity=36.7816091954023, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI17737361, Length=254, Percent_Identity=31.1023622047244, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=27.9352226720648, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI18859837, Length=230, Percent_Identity=31.7391304347826, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24644337, Length=169, Percent_Identity=33.7278106508876, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=30.6122448979592, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24641232, Length=216, Percent_Identity=29.6296296296296, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24581726, Length=177, Percent_Identity=25.9887005649718, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24648693, Length=204, Percent_Identity=30.8823529411765, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21355889, Length=204, Percent_Identity=30.8823529411765, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24641388, Length=205, Percent_Identity=31.7073170731707, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281364494, Length=199, Percent_Identity=27.6381909547739, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI116007236, Length=203, Percent_Identity=29.064039408867, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640442, Length=204, Percent_Identity=29.4117647058824, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161076933, Length=190, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24584748, Length=190, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355631, Length=174, Percent_Identity=28.735632183908, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011283
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.36 [H]

Molecular weight: Translated: 26290; Mature: 26159

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MSQRIAYVTGGMGGIGTSICQRLSKDGFKVVAGCGPNSPRRVKWLEDQKALGYDFIASEG
CCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCCCCCCCCEEECCCC
NVGDWDSTKEAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTHEDWTAVIDTNLTSLFNVT
CCCCCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCHHEEECCCHHHHHHHH
KQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVATKGVTVNT
HHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEC
VSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGGPEEIGSIVAWLASNDSGFATGADFSLN
CCCCCCCHHHHHHHCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEEC
GGLHMG
CCCCCC
>Mature Secondary Structure 
SQRIAYVTGGMGGIGTSICQRLSKDGFKVVAGCGPNSPRRVKWLEDQKALGYDFIASEG
CCEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCCCCCCCCEEECCCC
NVGDWDSTKEAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTHEDWTAVIDTNLTSLFNVT
CCCCCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCHHEEECCCHHHHHHHH
KQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVATKGVTVNT
HHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEC
VSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGGPEEIGSIVAWLASNDSGFATGADFSLN
CCCCCCCHHHHHHHCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEEC
GGLHMG
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2670935 [H]