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The map label for this gene is ttuB [H]

Identifier: 116689753

GI number: 116689753

Start: 1923318

End: 1924598

Strand: Reverse

Name: ttuB [H]

Synonym: Bcen2424_1732

Alternate gene names: 116689753

Gene position: 1924598-1923318 (Counterclockwise)

Preceding gene: 116689754

Following gene: 116689752

Centisome position: 55.24

GC content: 66.2

Gene sequence:

>1281_bases
ATGGCAGCCAATCTCGCAGCCCGTCGGTGGTGGACGATCATGCCGATCGTCTTCATCACCTACAGCCTCGCTTACCTCGA
TCGCGCGAACTACGGGTTCGCGGCGGCGGCCGGCATCAACCAGGATCTCGGCATCAGCAAGGGCCTGTCGTCGCTGATCG
GCGCGCTGTTCTTCCTCGGCTACTTCTTCTTCCAGATCCCCGGCGCGATCTACGCGGAACGCCGCAGCGTGAAGAAGCTC
GTGTTCGTCAGCCTCGTGCTGTGGGGCGGCTGCGCGGCGCTGACCGGCGTGGTCAGCAACATCCCGTCGCTGATGGCGAT
CCGCTTCGTGCTGGGCATCGTCGAGGCGGCCGTGATGCCGGCGATGCTGATCTACATCAGCAACTGGTTCACGAAGAACG
AGCGCTCGCGCGCGAACACGTTCCTGATCCTCGGCAACCCGGTCACCGTGCTGTGGATGTCGATCGTGTCGGGCTATCTC
GTGCATGAATTCGGCTGGCGCCACATGTTCATCGCCGAAGGCGTGCCGGCCGTCATCTGGGCCGTGTGCTGGTGGGTCCT
CGTGCAGGATAAGCCGGCCGATTCGCCGTGGTTGAGCGCGCAGGAAAAGCGCGACCTCGACGCCGCGCTCGCGGCCGAGC
AGGCGGCGATCAAGCCCGTGCGCAACTATGGCGAGGCGTTCCGTTCGCCGGCCGTGATCAAGCTGTGCGCGCAGTATTTC
TGCTGGAGCATCGGCGTGTACGGCTTCGTGCTGTGGCTGCCGTCGATCGTGAAGAACGGCTCCGACCTCGGGATGGTCGC
GACCGGCTGGCTGTCCGCGCTGCCGTACCTCGCGGCGACGATCGCGATGCTCGCCGCTTCGTGGGCATCCGACAAGGTCG
GCTCGCGCCGCGGCTTCGTGTGGCCGTTCCTGCTGGTCGGCGCGGCCGCGTTCGCCGCGTCGTATGCGCTCGGTTCGTCG
CATTTCTGGATTTCGTACGCGCTGCTGGTCGTCGCGGGCGCCGCGATGTATGCGCCGTACGGGCCGTTCTTCGCGATCGT
GCCGGAACTGCTGCCGAAGAACGTCGCCGGCGGCGCGATGGCGCTGATCAACAGCATGGGCGCGCTCGGCTCGTTCGTCG
GCTCGTACTTCGTCGGCTATCTGAACGGTGCGACCGGGTCACCCGTCGCGTCGTATGCATTCATGAGCGCCGCGCTCGTC
GCCGCGGTGATCCTCACGCTGTCCGTCAAACCCCAGGCGCGCGATGCGCATCCGCTCGCGGCGCCGCTGCAAGGAAAATG
A

Upstream 100 bases:

>100_bases
ACAATCCGCGGATCCATTTCGTGCGCGATGCACAGTAGTTTTGTTCGAGGCCGGGCAGGCGCCAGTGCGCCCACTCCGGT
CCATATACGGAGACACTCTC

Downstream 100 bases:

>100_bases
AACGATGAAGCCCCGTATCGTCGCGTACAAGCCGCTGCCCGATGACGTTCTCGCGTACCTGCGCGAGCATGCGGACGTCG
TGCAGGCCGACGGCGCCGAC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MAANLAARRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGISKGLSSLIGALFFLGYFFFQIPGAIYAERRSVKKL
VFVSLVLWGGCAALTGVVSNIPSLMAIRFVLGIVEAAVMPAMLIYISNWFTKNERSRANTFLILGNPVTVLWMSIVSGYL
VHEFGWRHMFIAEGVPAVIWAVCWWVLVQDKPADSPWLSAQEKRDLDAALAAEQAAIKPVRNYGEAFRSPAVIKLCAQYF
CWSIGVYGFVLWLPSIVKNGSDLGMVATGWLSALPYLAATIAMLAASWASDKVGSRRGFVWPFLLVGAAAFAASYALGSS
HFWISYALLVVAGAAMYAPYGPFFAIVPELLPKNVAGGAMALINSMGALGSFVGSYFVGYLNGATGSPVASYAFMSAALV
AAVILTLSVKPQARDAHPLAAPLQGK

Sequences:

>Translated_426_residues
MAANLAARRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGISKGLSSLIGALFFLGYFFFQIPGAIYAERRSVKKL
VFVSLVLWGGCAALTGVVSNIPSLMAIRFVLGIVEAAVMPAMLIYISNWFTKNERSRANTFLILGNPVTVLWMSIVSGYL
VHEFGWRHMFIAEGVPAVIWAVCWWVLVQDKPADSPWLSAQEKRDLDAALAAEQAAIKPVRNYGEAFRSPAVIKLCAQYF
CWSIGVYGFVLWLPSIVKNGSDLGMVATGWLSALPYLAATIAMLAASWASDKVGSRRGFVWPFLLVGAAAFAASYALGSS
HFWISYALLVVAGAAMYAPYGPFFAIVPELLPKNVAGGAMALINSMGALGSFVGSYFVGYLNGATGSPVASYAFMSAALV
AAVILTLSVKPQARDAHPLAAPLQGK
>Mature_425_residues
AANLAARRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGISKGLSSLIGALFFLGYFFFQIPGAIYAERRSVKKLV
FVSLVLWGGCAALTGVVSNIPSLMAIRFVLGIVEAAVMPAMLIYISNWFTKNERSRANTFLILGNPVTVLWMSIVSGYLV
HEFGWRHMFIAEGVPAVIWAVCWWVLVQDKPADSPWLSAQEKRDLDAALAAEQAAIKPVRNYGEAFRSPAVIKLCAQYFC
WSIGVYGFVLWLPSIVKNGSDLGMVATGWLSALPYLAATIAMLAASWASDKVGSRRGFVWPFLLVGAAAFAASYALGSSH
FWISYALLVVAGAAMYAPYGPFFAIVPELLPKNVAGGAMALINSMGALGSFVGSYFVGYLNGATGSPVASYAFMSAALVA
AVILTLSVKPQARDAHPLAAPLQGK

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9945322, Length=364, Percent_Identity=24.7252747252747, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI9966811, Length=367, Percent_Identity=25.0681198910082, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI6912666, Length=248, Percent_Identity=25, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI21322234, Length=259, Percent_Identity=26.2548262548263, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI154350196, Length=365, Percent_Identity=22.7397260273973, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI148743791, Length=194, Percent_Identity=21.1340206185567, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87082071, Length=372, Percent_Identity=28.2258064516129, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI87082320, Length=436, Percent_Identity=24.7706422018349, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1789515, Length=420, Percent_Identity=24.047619047619, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI2367379, Length=287, Percent_Identity=25.0871080139373, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1789152, Length=405, Percent_Identity=22.2222222222222, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17552542, Length=320, Percent_Identity=26.875, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI115533554, Length=366, Percent_Identity=26.5027322404372, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115533556, Length=366, Percent_Identity=26.5027322404372, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560030, Length=282, Percent_Identity=25.886524822695, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17535049, Length=431, Percent_Identity=25.0580046403712, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI86561091, Length=334, Percent_Identity=26.3473053892216, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25141318, Length=334, Percent_Identity=26.3473053892216, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25141316, Length=334, Percent_Identity=26.3473053892216, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25141341, Length=276, Percent_Identity=26.8115942028986, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193205400, Length=273, Percent_Identity=24.1758241758242, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32565916, Length=173, Percent_Identity=26.0115606936416, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI32565914, Length=173, Percent_Identity=26.0115606936416, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17566884, Length=209, Percent_Identity=25.3588516746411, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322612, Length=207, Percent_Identity=26.0869565217391, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24580790, Length=349, Percent_Identity=25.5014326647564, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24583789, Length=356, Percent_Identity=23.876404494382, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI45550460, Length=398, Percent_Identity=24.1206030150754, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24655255, Length=360, Percent_Identity=24.4444444444444, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24584153, Length=388, Percent_Identity=22.680412371134, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19922400, Length=239, Percent_Identity=23.8493723849372, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24654215, Length=239, Percent_Identity=23.8493723849372, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24655271, Length=300, Percent_Identity=24.3333333333333, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI20130135, Length=300, Percent_Identity=24.3333333333333, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648416, Length=271, Percent_Identity=25.0922509225092, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356189, Length=271, Percent_Identity=25.0922509225092, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573708, Length=264, Percent_Identity=24.6212121212121, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28573707, Length=264, Percent_Identity=24.6212121212121, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28573299, Length=300, Percent_Identity=22, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20129235, Length=389, Percent_Identity=25.4498714652956, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI62484226, Length=282, Percent_Identity=25.886524822695, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24653727, Length=236, Percent_Identity=26.6949152542373, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641682, Length=282, Percent_Identity=23.4042553191489, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24658674, Length=277, Percent_Identity=22.0216606498195, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24639764, Length=278, Percent_Identity=23.3812949640288, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45793; Mature: 45662

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCC
>Mature Secondary Structure 
AANLAARRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGISKGLSSLIGALFFLG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHH
YFFFQIPGAIYAERRSVKKLVFVSLVLWGGCAALTGVVSNIPSLMAIRFVLGIVEAAVMP
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLIYISNWFTKNERSRANTFLILGNPVTVLWMSIVSGYLVHEFGWRHMFIAEGVPAVIW
HHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEHHCCHHHHHH
AVCWWVLVQDKPADSPWLSAQEKRDLDAALAAEQAAIKPVRNYGEAFRSPAVIKLCAQYF
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
CWSIGVYGFVLWLPSIVKNGSDLGMVATGWLSALPYLAATIAMLAASWASDKVGSRRGFV
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
WPFLLVGAAAFAASYALGSSHFWISYALLVVAGAAMYAPYGPFFAIVPELLPKNVAGGAM
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHH
ALINSMGALGSFVGSYFVGYLNGATGSPVASYAFMSAALVAAVILTLSVKPQARDAHPLA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
APLQGK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]