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The map label for this gene is lgrB [H]

Identifier: 116689663

GI number: 116689663

Start: 1817908

End: 1822896

Strand: Direct

Name: lgrB [H]

Synonym: Bcen2424_1641

Alternate gene names: 116689663

Gene position: 1817908-1822896 (Clockwise)

Preceding gene: 116689662

Following gene: 116689664

Centisome position: 52.18

GC content: 72.46

Gene sequence:

>4989_bases
ATGACGAAGGTTCAACCCGACTGGCTGGCGCTCGCGACGCGTTTCGCGCAACTGCCCGACGCGCAGCGCGCGGTCTTCAT
CGACAAGCTCGGCGCGGCCGGCATCGACTTCCGCGTGCTGCCGATCCCGCCGCGCACGCCGCGCAGCGACCGCGTGCCGG
CATCGTTCGCGCAGACGCGGCTGTGGCTGCACGCGCGGCTGATCGATGCGCCGGACGCGTATCACATCACCGAGCGCCTC
GCGCTGACGGGCCCGCTCGACGGGCATGCGTTGCGTCTCGCGTGCGATGCGCTGATCGCGCGCCATGAGGCGCTGCGCAC
GACCTTCGACGAAGCGCAGGACGGCGTCGCGCAGACGATCCATGCGCCGTTGCGCTGCCCGTGGCGCGAAACCGATCTCG
AAGCGTTGCCGGATGCGCAGCGCGCAGCGCGCGCGGAAGCCGTCGCGACGGCCGACGAAGCCGAACCGTTCGATCTCGGC
ACGGCGCCGCTCGTGCGCGCGCATCTGGTCCGCTTCGACGCGACGCATCACTGGCTCGCACTGACCGTCCATCACATCGT
GTCGGACGGCTGGTCGTCGGGCGTGATGCTGGAAGAACTCGCGGCGTTCTATCGCGCGTATGCGTCCGACCGGCCGGTGC
CGCTCGCGCCGCTGCCGATCCAGTACGCCGACTACGCGCTGTGGCAGCGCCGCTGGCTCGATGCCGGCGAGCGCGACCGT
CAGCTCGCGTTCTGGCGCGAACGGCTCGATCCGCAGCGCGGCGTGCTGACGCTGCCGGGCGCGACCGCGCGGCCGGCCCG
TCGCAGTGCGCGCGGCGCGCGTCACGTGTTTTCGCTCGACGCGCGTATCGGTGCGCAGTTGCGCGCATTCGCGGCCGCAT
CGGGCGCGACGCCGTTCGCGGTGCTGCTCGCCGTGCTCGATGCGCTGCTGGCGCGCGCGACCGGCGACGCACGGATCTGC
GTCGGCGTGCCGGCCGCAAACCGCGAGCGCGCGGAAGTCGCCGGCCTGATCGGCTTCTTCGTCAACACGCTCGCGATCGA
CGTCGACGTGCCCGCGCACGGCGATTTCTCGTCGCTGGTCGCGCGTACGCAGCGCGCACTCGTCGACGCGCAGATGCACC
AGGACGTGCCGTTCGAGCAGGTGGTCGACGCGCTCGGCGTGCCGCGCAGCGCGAGCCACCATCCGCTGTTCCAGGTGATG
GCCGCGTACGGCGAACGCCGCGCGCTGCCGCCCCTCGGCGCGGCGTCGGCCGCGTTGCTGCCGTCCGGTACGCCGTCCGC
GAAGTTCGACCTGACGTTGTCCGTCGAAGCGACGCCGGACGGCACCTTCGACGCCGCCTTCATCTACGCGCTCGACCTGT
TCGACGCGGATGCGATCGCGCGGCTGGCCGCGCGCTTCGTCACGCTGCTGACCGATGCGCTCGCGCGTCCGGATCTGCCG
ATCGGCGATCTCGACTGGCTGCCTGCCGACGAACGCGCACAGCTCTTCGCATGGAACGCGCCGGCCGGCGCGACCGATGC
CGAGCCGTTCGTACCGGTGCATGCACGCATCGCCGCGCATGCACAGGCGCGGCCCGATGCACGCGGCGTCGCCGATATCG
ATCGCGCATTGACGCGCGGCGAAGTCGATGCCCGTGCCGCACGTTTGGCGCGCCATCTGGTGGTGGCCGGCGTGCGGCCC
GAGATGCGCGTGGGCGTCGCGCTGCAGCGCTCGGTCGACCTGCTCGTCGCGCTAATCGCGGTGCTGAAGTCGGGCGCCGC
GTTCGTGCCGCTCGATCCGGCGCATCCACGCGAACGGCTCGCGCAGATCGTCGGCGATGCGGCCATCGCGCACGTGCTGA
CCGACGCCGCGAGCGCCGCGTCGCTGCCCGACTTGCCTGAACTGCGCATCTGGCGCGCGGACGCAATCGATGCGCTCGAC
GAAGCCGCGCACGTCGCGCTGCCGGACGTGCTGCCCGGCCACGCGGCGTATGCGATCTACACGTCGGGTTCGACCGGCAA
GCCGAAGGGCGTGATCGTCGACCACGCGTCGTTCGCGCTGCATTGCGCGGCGATCGCCGAGCGCTACGGCGCGGGTGAAA
ACGACGTGTTCCTGTTGTTCCAGTCGGTGAATTTCGACGGCGCGCACGAAGGCTGGTTTTCGCAATACATGTCGGGCGCC
GCCGTGTCGGTGACGGCCGACGTGCTGTGGCCGCCCGCGCAGACCTGCGCGATGATGATCCGCGACGGCGTGACGATGAC
CTACGTGCCGCCCGGCTGCGCGGCCCAGCTCGCGGAATGGGCGCTCGCGCACGGCGCACCGCCGACGCTGCGTTCGCTGA
CCGTCGGCGGCGAGGCGACGTCGCGCGAGGCGTTCGCGATGCTGCGCCGCGCGCTGCCGAACGTGCGCGTGGTCAACGGC
TATGGCCCGACCGAAACCGTCATCACGCCGACGCTGTGGATGTTCCGACCCGGCGACGAGCTCGCGAAGCTCGGCGATGC
CGCGTATCTGCCGATCGGCACGCTGGTCGGCGCGCGCACCGCGCACGTGCTCGACACGCGGCTGCATCCGCTGCCGGTCG
GCGTGATCGGCGAACTGTACCTGGGCGGCGAGGGCATCGGCGTCGCGCGCGGCTACCTCGACCGTCCGGCGCTGACCGCC
GAGCGTTTCGTGCCCGATCCGTACGGCGCGCCGGGCGCGCGACTGTACCGTACCGGCGACCTCGTGCGGCGCCGCGCGGA
CGGCGTGTTCGATTTCATCGGCCGCGTCGATCACCAGGTGAAGCTGCGCGGCCTGCGCATCGAACTCGGCGAAATCGAAG
CGCAGCTCGCCGCGCACGATGCGGTGCGCGAAGCCTGCGCGGTCGTGCACGGGCAGGGCGCGCTCGCGCAGCTCGTCGCG
TACGTCGAGCTGACCGCCGAAGCGCAGGCGGCCGCGCAGCCGGTCGAAGCCGCGACGCTCGACGCGCACCTGCACCGCAC
GCTGCCCGATTACATGGTGCCCGCGCAACTGATCGTGCTCGACGCGCTGCCGCGCAACGCGAACAGCAAGGTCGACCGTG
CGCGGCTGCCGGCGCCGGTGCGCGTCGAACGTGCGTACGAGGCGCCGCACGACGGCGACGAAGCCGCGCTCGCGGCGATC
TGGTGCGACGTGTTGAACCTGGAGCGCGTCGGCCGCGGCGATCACTTCTTCGATCTCGGCGGTCATTCGCTCGCCGCCGT
GCGTGTCGCGACGCGCGTGGCCGAACGGCTCGGCCGCGACGTGCCGGTGCGCGCGCTGTTCGAGGCGCCCGTGCTCGCGC
AATACGCGCGGCAGGTGGCCGATGCGCCGCGCGCCGCGCATACCGGCGCCACGGCGCCGGGCGTCGCGGTGGCCAAACCG
GACGCTCACGGCGTGTGGCCGCTGTCACCCGCGCAGCTCGGCCTGTGGTTCCTGTGGCGCGCGCAGCCGGACAGCGCTGC
GTACAACATTCCGGTCGCGCTGCGTGTGCGCGGCCCGCTCGATGTCGATGCGCTGCGCGCCGCGTTCGCGGATGCGGCAG
CCGAGCATCCGGCGCTGCGTGCACGGCTCGTCGCCCGCGACGGCGCGCTGCCGGGCCAACGGATCGACGCAGACGTTGCC
GTCGACCTGCCGGTGATCGACCTGTCGGCCCAAACCGATGCGCTGGCCCGCGCGGCCGCGCTGACCGACGAGGATGCGCT
CGCGCCGTTCGACCTCACGGCCGACGCGCCGCTGTGGCGCGCCCGCGTGTTGCGACTCGGGGCGGACGATCACGTGCTGT
CGGTGACGATCCATCACATCGTATCGGATGGCGAATCGATCGAGCTGTGGCTCGACGCGGTGCGGGCCCGCTATGTCGCC
CGCATGCAGCGCGGCGCCGCTCTGGTCGACGAAGCCGTCGAACCGGCCGCCCAACCGCTCGTGCTGCCCGCGCCATGCCA
TCCGGCGCGCGTCGCGTACTGGCGCGATGCACTCGCCGATCTGCCGTCGCGCGTGTTGCCGCAGCGCACCGATGCGCCGG
CCGTGCCGCAATGGCGTGCGGCCCGCATCGCGTTCGAATTCGATACGCAGCTGATTCGCGCCGCGCGCGACGCCGCGTCG
GCCTCGCACGCGACGCTGCCGATGCTGCTGCACGCGGCGCTCAACACCGCGCTGTTCCGCGCGACGGGCGCGGCCGACCA
GCCGGTCGGCGTGCTCGCGTCGACGCGCGAACTCACGGGCGACGCGGCGCGTACCGCGCTGGGCCTCTTCATCAACTCGG
TCGTCGTGCGCACGCGGATCGACCCGGCCGCGCGCCGCGCCGACGTGCTGGCGCAAGTGCGCGACACGGCGCTCGCCGCG
TATGCGCATGCCGACGTGCCGTTCGCCGACGTCGTCGCCGCGCTGCGTGCGCCGCGCGCCGCGCAGGCCAATCCGCTGTT
CCAGGTGATGTTCAACTACCTGCGCCCGACCGGCGCCGCCGCACGCGACTGGGCCGGCCTGTCGCTGGCCGAATTTGACG
ACGTGCGTCATCGCGTCGTGTTCACGCTGGAGCTGGACGTCGTCGAGCATCCGGACGGCCGCGTGAGCGCCGCGTTCTCG
TATGCGGACGAACTGCTCGCGCGCGATTTCGTCGAGGCGCTCGTCGATCTGTACCACGACGAAGTCGCGCGTTTCGCCGG
CGCGTCGGAAGCGGCGCTCGGTGCACCGGATGCGCAAGCAGCCAAGCCCACTTCGTTCGACGCGCGCGCCAACGGCGCAA
CCCGGCCGAACGCAACGCCGTCGCATGCCGCCGCCGCGCTCGCCGCGCTGTGGTCGGACACGTTCGCGACGGCCGCCCCC
GAGCCCGATGCGGACCTGTTCGAAGCCGGCGCGACGTCGTTCGACGTCGTGCGCTTCGTCGACGCGGCCGGCCGTGCCGG
CCATGCGCTGACGGTGGCCGACGTGTTCGCGGCACCGACGCTCGCGGCGCTCGGCGCGCGGCTCGATGCGCACGCGGAAA
CGGGACAGGAGGCGCGCCATGCTGGCTGA

Upstream 100 bases:

>100_bases
GGAAGCGATCGACGCGGCCTGCGCGGCACGCGGCGCGACCGATGCGGCGAGCGCGATCGACGCGCTGCTCGGCGAACTGG
AAACCCAATAAGGACGACGG

Downstream 100 bases:

>100_bases
AGTGCGCCCGGACGGATTCACGATGCTCGATACCTACCGGCTCGCGTTCGCGGACGGCCTGTTCGCCGCGCGCGATGGCG
CGGAGATCCGCGTCGCGCAG

Product: amino acid adenylation domain-containing protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent alanine adenylase; AlaA; Alanine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent alanine adenylase; AlaA; Alanine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1662; Mature: 1661

Protein sequence:

>1662_residues
MTKVQPDWLALATRFAQLPDAQRAVFIDKLGAAGIDFRVLPIPPRTPRSDRVPASFAQTRLWLHARLIDAPDAYHITERL
ALTGPLDGHALRLACDALIARHEALRTTFDEAQDGVAQTIHAPLRCPWRETDLEALPDAQRAARAEAVATADEAEPFDLG
TAPLVRAHLVRFDATHHWLALTVHHIVSDGWSSGVMLEELAAFYRAYASDRPVPLAPLPIQYADYALWQRRWLDAGERDR
QLAFWRERLDPQRGVLTLPGATARPARRSARGARHVFSLDARIGAQLRAFAAASGATPFAVLLAVLDALLARATGDARIC
VGVPAANRERAEVAGLIGFFVNTLAIDVDVPAHGDFSSLVARTQRALVDAQMHQDVPFEQVVDALGVPRSASHHPLFQVM
AAYGERRALPPLGAASAALLPSGTPSAKFDLTLSVEATPDGTFDAAFIYALDLFDADAIARLAARFVTLLTDALARPDLP
IGDLDWLPADERAQLFAWNAPAGATDAEPFVPVHARIAAHAQARPDARGVADIDRALTRGEVDARAARLARHLVVAGVRP
EMRVGVALQRSVDLLVALIAVLKSGAAFVPLDPAHPRERLAQIVGDAAIAHVLTDAASAASLPDLPELRIWRADAIDALD
EAAHVALPDVLPGHAAYAIYTSGSTGKPKGVIVDHASFALHCAAIAERYGAGENDVFLLFQSVNFDGAHEGWFSQYMSGA
AVSVTADVLWPPAQTCAMMIRDGVTMTYVPPGCAAQLAEWALAHGAPPTLRSLTVGGEATSREAFAMLRRALPNVRVVNG
YGPTETVITPTLWMFRPGDELAKLGDAAYLPIGTLVGARTAHVLDTRLHPLPVGVIGELYLGGEGIGVARGYLDRPALTA
ERFVPDPYGAPGARLYRTGDLVRRRADGVFDFIGRVDHQVKLRGLRIELGEIEAQLAAHDAVREACAVVHGQGALAQLVA
YVELTAEAQAAAQPVEAATLDAHLHRTLPDYMVPAQLIVLDALPRNANSKVDRARLPAPVRVERAYEAPHDGDEAALAAI
WCDVLNLERVGRGDHFFDLGGHSLAAVRVATRVAERLGRDVPVRALFEAPVLAQYARQVADAPRAAHTGATAPGVAVAKP
DAHGVWPLSPAQLGLWFLWRAQPDSAAYNIPVALRVRGPLDVDALRAAFADAAAEHPALRARLVARDGALPGQRIDADVA
VDLPVIDLSAQTDALARAAALTDEDALAPFDLTADAPLWRARVLRLGADDHVLSVTIHHIVSDGESIELWLDAVRARYVA
RMQRGAALVDEAVEPAAQPLVLPAPCHPARVAYWRDALADLPSRVLPQRTDAPAVPQWRAARIAFEFDTQLIRAARDAAS
ASHATLPMLLHAALNTALFRATGAADQPVGVLASTRELTGDAARTALGLFINSVVVRTRIDPAARRADVLAQVRDTALAA
YAHADVPFADVVAALRAPRAAQANPLFQVMFNYLRPTGAAARDWAGLSLAEFDDVRHRVVFTLELDVVEHPDGRVSAAFS
YADELLARDFVEALVDLYHDEVARFAGASEAALGAPDAQAAKPTSFDARANGATRPNATPSHAAAALAALWSDTFATAAP
EPDADLFEAGATSFDVVRFVDAAGRAGHALTVADVFAAPTLAALGARLDAHAETGQEARHAG

Sequences:

>Translated_1662_residues
MTKVQPDWLALATRFAQLPDAQRAVFIDKLGAAGIDFRVLPIPPRTPRSDRVPASFAQTRLWLHARLIDAPDAYHITERL
ALTGPLDGHALRLACDALIARHEALRTTFDEAQDGVAQTIHAPLRCPWRETDLEALPDAQRAARAEAVATADEAEPFDLG
TAPLVRAHLVRFDATHHWLALTVHHIVSDGWSSGVMLEELAAFYRAYASDRPVPLAPLPIQYADYALWQRRWLDAGERDR
QLAFWRERLDPQRGVLTLPGATARPARRSARGARHVFSLDARIGAQLRAFAAASGATPFAVLLAVLDALLARATGDARIC
VGVPAANRERAEVAGLIGFFVNTLAIDVDVPAHGDFSSLVARTQRALVDAQMHQDVPFEQVVDALGVPRSASHHPLFQVM
AAYGERRALPPLGAASAALLPSGTPSAKFDLTLSVEATPDGTFDAAFIYALDLFDADAIARLAARFVTLLTDALARPDLP
IGDLDWLPADERAQLFAWNAPAGATDAEPFVPVHARIAAHAQARPDARGVADIDRALTRGEVDARAARLARHLVVAGVRP
EMRVGVALQRSVDLLVALIAVLKSGAAFVPLDPAHPRERLAQIVGDAAIAHVLTDAASAASLPDLPELRIWRADAIDALD
EAAHVALPDVLPGHAAYAIYTSGSTGKPKGVIVDHASFALHCAAIAERYGAGENDVFLLFQSVNFDGAHEGWFSQYMSGA
AVSVTADVLWPPAQTCAMMIRDGVTMTYVPPGCAAQLAEWALAHGAPPTLRSLTVGGEATSREAFAMLRRALPNVRVVNG
YGPTETVITPTLWMFRPGDELAKLGDAAYLPIGTLVGARTAHVLDTRLHPLPVGVIGELYLGGEGIGVARGYLDRPALTA
ERFVPDPYGAPGARLYRTGDLVRRRADGVFDFIGRVDHQVKLRGLRIELGEIEAQLAAHDAVREACAVVHGQGALAQLVA
YVELTAEAQAAAQPVEAATLDAHLHRTLPDYMVPAQLIVLDALPRNANSKVDRARLPAPVRVERAYEAPHDGDEAALAAI
WCDVLNLERVGRGDHFFDLGGHSLAAVRVATRVAERLGRDVPVRALFEAPVLAQYARQVADAPRAAHTGATAPGVAVAKP
DAHGVWPLSPAQLGLWFLWRAQPDSAAYNIPVALRVRGPLDVDALRAAFADAAAEHPALRARLVARDGALPGQRIDADVA
VDLPVIDLSAQTDALARAAALTDEDALAPFDLTADAPLWRARVLRLGADDHVLSVTIHHIVSDGESIELWLDAVRARYVA
RMQRGAALVDEAVEPAAQPLVLPAPCHPARVAYWRDALADLPSRVLPQRTDAPAVPQWRAARIAFEFDTQLIRAARDAAS
ASHATLPMLLHAALNTALFRATGAADQPVGVLASTRELTGDAARTALGLFINSVVVRTRIDPAARRADVLAQVRDTALAA
YAHADVPFADVVAALRAPRAAQANPLFQVMFNYLRPTGAAARDWAGLSLAEFDDVRHRVVFTLELDVVEHPDGRVSAAFS
YADELLARDFVEALVDLYHDEVARFAGASEAALGAPDAQAAKPTSFDARANGATRPNATPSHAAAALAALWSDTFATAAP
EPDADLFEAGATSFDVVRFVDAAGRAGHALTVADVFAAPTLAALGARLDAHAETGQEARHAG
>Mature_1661_residues
TKVQPDWLALATRFAQLPDAQRAVFIDKLGAAGIDFRVLPIPPRTPRSDRVPASFAQTRLWLHARLIDAPDAYHITERLA
LTGPLDGHALRLACDALIARHEALRTTFDEAQDGVAQTIHAPLRCPWRETDLEALPDAQRAARAEAVATADEAEPFDLGT
APLVRAHLVRFDATHHWLALTVHHIVSDGWSSGVMLEELAAFYRAYASDRPVPLAPLPIQYADYALWQRRWLDAGERDRQ
LAFWRERLDPQRGVLTLPGATARPARRSARGARHVFSLDARIGAQLRAFAAASGATPFAVLLAVLDALLARATGDARICV
GVPAANRERAEVAGLIGFFVNTLAIDVDVPAHGDFSSLVARTQRALVDAQMHQDVPFEQVVDALGVPRSASHHPLFQVMA
AYGERRALPPLGAASAALLPSGTPSAKFDLTLSVEATPDGTFDAAFIYALDLFDADAIARLAARFVTLLTDALARPDLPI
GDLDWLPADERAQLFAWNAPAGATDAEPFVPVHARIAAHAQARPDARGVADIDRALTRGEVDARAARLARHLVVAGVRPE
MRVGVALQRSVDLLVALIAVLKSGAAFVPLDPAHPRERLAQIVGDAAIAHVLTDAASAASLPDLPELRIWRADAIDALDE
AAHVALPDVLPGHAAYAIYTSGSTGKPKGVIVDHASFALHCAAIAERYGAGENDVFLLFQSVNFDGAHEGWFSQYMSGAA
VSVTADVLWPPAQTCAMMIRDGVTMTYVPPGCAAQLAEWALAHGAPPTLRSLTVGGEATSREAFAMLRRALPNVRVVNGY
GPTETVITPTLWMFRPGDELAKLGDAAYLPIGTLVGARTAHVLDTRLHPLPVGVIGELYLGGEGIGVARGYLDRPALTAE
RFVPDPYGAPGARLYRTGDLVRRRADGVFDFIGRVDHQVKLRGLRIELGEIEAQLAAHDAVREACAVVHGQGALAQLVAY
VELTAEAQAAAQPVEAATLDAHLHRTLPDYMVPAQLIVLDALPRNANSKVDRARLPAPVRVERAYEAPHDGDEAALAAIW
CDVLNLERVGRGDHFFDLGGHSLAAVRVATRVAERLGRDVPVRALFEAPVLAQYARQVADAPRAAHTGATAPGVAVAKPD
AHGVWPLSPAQLGLWFLWRAQPDSAAYNIPVALRVRGPLDVDALRAAFADAAAEHPALRARLVARDGALPGQRIDADVAV
DLPVIDLSAQTDALARAAALTDEDALAPFDLTADAPLWRARVLRLGADDHVLSVTIHHIVSDGESIELWLDAVRARYVAR
MQRGAALVDEAVEPAAQPLVLPAPCHPARVAYWRDALADLPSRVLPQRTDAPAVPQWRAARIAFEFDTQLIRAARDAASA
SHATLPMLLHAALNTALFRATGAADQPVGVLASTRELTGDAARTALGLFINSVVVRTRIDPAARRADVLAQVRDTALAAY
AHADVPFADVVAALRAPRAAQANPLFQVMFNYLRPTGAAARDWAGLSLAEFDDVRHRVVFTLELDVVEHPDGRVSAAFSY
ADELLARDFVEALVDLYHDEVARFAGASEAALGAPDAQAAKPTSFDARANGATRPNATPSHAAAALAALWSDTFATAAPE
PDADLFEAGATSFDVVRFVDAAGRAGHALTVADVFAAPTLAALGARLDAHAETGQEARHAG

Specific function: Activates the 3rd to 6th amino acids (Ala, D-Leu, Ala and D-Val) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 4th (D-Leu) and the 6th (D-Val) amino acids [H

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=613, Percent_Identity=23.1647634584013, Blast_Score=104, Evalue=6e-22,
Organism=Homo sapiens, GI38505220, Length=366, Percent_Identity=25.9562841530055, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI42544132, Length=368, Percent_Identity=22.554347826087, Blast_Score=74, Evalue=1e-12,
Organism=Homo sapiens, GI28416953, Length=383, Percent_Identity=25.5874673629243, Blast_Score=70, Evalue=2e-11,
Organism=Homo sapiens, GI157311624, Length=491, Percent_Identity=23.0142566191446, Blast_Score=69, Evalue=3e-11,
Organism=Homo sapiens, GI157311622, Length=491, Percent_Identity=23.0142566191446, Blast_Score=69, Evalue=3e-11,
Organism=Escherichia coli, GI1786801, Length=1065, Percent_Identity=29.7652582159624, Blast_Score=315, Evalue=2e-86,
Organism=Escherichia coli, GI1790505, Length=375, Percent_Identity=27.2, Blast_Score=78, Evalue=6e-15,
Organism=Escherichia coli, GI145693145, Length=520, Percent_Identity=23.0769230769231, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI221142682, Length=509, Percent_Identity=22.3968565815324, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1786810, Length=525, Percent_Identity=24.952380952381, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17550940, Length=1074, Percent_Identity=19.8324022346369, Blast_Score=130, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17556356, Length=531, Percent_Identity=23.1638418079096, Blast_Score=124, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17558820, Length=529, Percent_Identity=24.7637051039698, Blast_Score=98, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI32563687, Length=510, Percent_Identity=24.9019607843137, Blast_Score=97, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6319591, Length=986, Percent_Identity=24.6450304259635, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24648676, Length=612, Percent_Identity=26.4705882352941, Blast_Score=145, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24581924, Length=370, Percent_Identity=25.6756756756757, Blast_Score=77, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 177385; Mature: 177254

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVQPDWLALATRFAQLPDAQRAVFIDKLGAAGIDFRVLPIPPRTPRSDRVPASFAQTR
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHH
LWLHARLIDAPDAYHITERLALTGPLDGHALRLACDALIARHEALRTTFDEAQDGVAQTI
HHHHEEEECCCCHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAPLRCPWRETDLEALPDAQRAARAEAVATADEAEPFDLGTAPLVRAHLVRFDATHHWLA
CCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHH
LTVHHIVSDGWSSGVMLEELAAFYRAYASDRPVPLAPLPIQYADYALWQRRWLDAGERDR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCH
QLAFWRERLDPQRGVLTLPGATARPARRSARGARHVFSLDARIGAQLRAFAAASGATPFA
HHHHHHHHCCCCCCEEECCCCCCCCHHHHHCCHHHEEEEHHHHHHHHHHHHHCCCCCHHH
VLLAVLDALLARATGDARICVGVPAANRERAEVAGLIGFFVNTLAIDVDVPAHGDFSSLV
HHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHH
ARTQRALVDAQMHQDVPFEQVVDALGVPRSASHHPLFQVMAAYGERRALPPLGAASAALL
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHCC
PSGTPSAKFDLTLSVEATPDGTFDAAFIYALDLFDADAIARLAARFVTLLTDALARPDLP
CCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCC
IGDLDWLPADERAQLFAWNAPAGATDAEPFVPVHARIAAHAQARPDARGVADIDRALTRG
CCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCC
EVDARAARLARHLVVAGVRPEMRVGVALQRSVDLLVALIAVLKSGAAFVPLDPAHPRERL
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHH
AQIVGDAAIAHVLTDAASAASLPDLPELRIWRADAIDALDEAAHVALPDVLPGHAAYAIY
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHCCCCCCCCCEEEEEE
TSGSTGKPKGVIVDHASFALHCAAIAERYGAGENDVFLLFQSVNFDGAHEGWFSQYMSGA
ECCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHCCC
AVSVTADVLWPPAQTCAMMIRDGVTMTYVPPGCAAQLAEWALAHGAPPTLRSLTVGGEAT
EEEEEEEECCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCHHEEEECCCCC
SREAFAMLRRALPNVRVVNGYGPTETVITPTLWMFRPGDELAKLGDAAYLPIGTLVGART
HHHHHHHHHHHCCCCEEEECCCCCCCEECCEEEEECCCHHHHHHCCCCCCCHHHHHHCCH
AHVLDTRLHPLPVGVIGELYLGGEGIGVARGYLDRPALTAERFVPDPYGAPGARLYRTGD
HHHHHCCCCCCCCCHHEEEEECCCCCCHHHCCCCCCCCCHHHCCCCCCCCCCCEEEHHHH
LVRRRADGVFDFIGRVDHQVKLRGLRIELGEIEAQLAAHDAVREACAVVHGQGALAQLVA
HHHHHHHHHHHHHHHCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
YVELTAEAQAAAQPVEAATLDAHLHRTLPDYMVPAQLIVLDALPRNANSKVDRARLPAPV
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHCCHHHEEEECCCCCCCCCCHHHCCCCCE
RVERAYEAPHDGDEAALAAIWCDVLNLERVGRGDHFFDLGGHSLAAVRVATRVAERLGRD
EEHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHCCC
VPVRALFEAPVLAQYARQVADAPRAAHTGATAPGVAVAKPDAHGVWPLSPAQLGLWFLWR
CCHHHHHHCHHHHHHHHHHHCCCCHHCCCCCCCCEEEECCCCCCCCCCCHHHCCEEEEEE
AQPDSAAYNIPVALRVRGPLDVDALRAAFADAAAEHPALRARLVARDGALPGQRIDADVA
CCCCCCEEECCEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEE
VDLPVIDLSAQTDALARAAALTDEDALAPFDLTADAPLWRARVLRLGADDHVLSVTIHHI
EECEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEHHH
VSDGESIELWLDAVRARYVARMQRGAALVDEAVEPAAQPLVLPAPCHPARVAYWRDALAD
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHH
LPSRVLPQRTDAPAVPQWRAARIAFEFDTQLIRAARDAASASHATLPMLLHAALNTALFR
CHHHHCCCCCCCCCCCCCHHEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
ATGAADQPVGVLASTRELTGDAARTALGLFINSVVVRTRIDPAARRADVLAQVRDTALAA
CCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
YAHADVPFADVVAALRAPRAAQANPLFQVMFNYLRPTGAAARDWAGLSLAEFDDVRHRVV
HHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCEEEE
FTLELDVVEHPDGRVSAAFSYADELLARDFVEALVDLYHDEVARFAGASEAALGAPDAQA
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
AKPTSFDARANGATRPNATPSHAAAALAALWSDTFATAAPEPDADLFEAGATSFDVVRFV
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHH
DAAGRAGHALTVADVFAAPTLAALGARLDAHAETGQEARHAG
HHCCCCCCEEEHHHHHHHHHHHHHHHHHHCHHHCCCHHHCCC
>Mature Secondary Structure 
TKVQPDWLALATRFAQLPDAQRAVFIDKLGAAGIDFRVLPIPPRTPRSDRVPASFAQTR
CCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHH
LWLHARLIDAPDAYHITERLALTGPLDGHALRLACDALIARHEALRTTFDEAQDGVAQTI
HHHHEEEECCCCHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAPLRCPWRETDLEALPDAQRAARAEAVATADEAEPFDLGTAPLVRAHLVRFDATHHWLA
CCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHH
LTVHHIVSDGWSSGVMLEELAAFYRAYASDRPVPLAPLPIQYADYALWQRRWLDAGERDR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCH
QLAFWRERLDPQRGVLTLPGATARPARRSARGARHVFSLDARIGAQLRAFAAASGATPFA
HHHHHHHHCCCCCCEEECCCCCCCCHHHHHCCHHHEEEEHHHHHHHHHHHHHCCCCCHHH
VLLAVLDALLARATGDARICVGVPAANRERAEVAGLIGFFVNTLAIDVDVPAHGDFSSLV
HHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHH
ARTQRALVDAQMHQDVPFEQVVDALGVPRSASHHPLFQVMAAYGERRALPPLGAASAALL
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHCC
PSGTPSAKFDLTLSVEATPDGTFDAAFIYALDLFDADAIARLAARFVTLLTDALARPDLP
CCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCC
IGDLDWLPADERAQLFAWNAPAGATDAEPFVPVHARIAAHAQARPDARGVADIDRALTRG
CCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCC
EVDARAARLARHLVVAGVRPEMRVGVALQRSVDLLVALIAVLKSGAAFVPLDPAHPRERL
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHH
AQIVGDAAIAHVLTDAASAASLPDLPELRIWRADAIDALDEAAHVALPDVLPGHAAYAIY
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHCCCCCCCCCEEEEEE
TSGSTGKPKGVIVDHASFALHCAAIAERYGAGENDVFLLFQSVNFDGAHEGWFSQYMSGA
ECCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHCCC
AVSVTADVLWPPAQTCAMMIRDGVTMTYVPPGCAAQLAEWALAHGAPPTLRSLTVGGEAT
EEEEEEEECCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCHHEEEECCCCC
SREAFAMLRRALPNVRVVNGYGPTETVITPTLWMFRPGDELAKLGDAAYLPIGTLVGART
HHHHHHHHHHHCCCCEEEECCCCCCCEECCEEEEECCCHHHHHHCCCCCCCHHHHHHCCH
AHVLDTRLHPLPVGVIGELYLGGEGIGVARGYLDRPALTAERFVPDPYGAPGARLYRTGD
HHHHHCCCCCCCCCHHEEEEECCCCCCHHHCCCCCCCCCHHHCCCCCCCCCCCEEEHHHH
LVRRRADGVFDFIGRVDHQVKLRGLRIELGEIEAQLAAHDAVREACAVVHGQGALAQLVA
HHHHHHHHHHHHHHHCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
YVELTAEAQAAAQPVEAATLDAHLHRTLPDYMVPAQLIVLDALPRNANSKVDRARLPAPV
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHCCHHHEEEECCCCCCCCCCHHHCCCCCE
RVERAYEAPHDGDEAALAAIWCDVLNLERVGRGDHFFDLGGHSLAAVRVATRVAERLGRD
EEHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHCCC
VPVRALFEAPVLAQYARQVADAPRAAHTGATAPGVAVAKPDAHGVWPLSPAQLGLWFLWR
CCHHHHHHCHHHHHHHHHHHCCCCHHCCCCCCCCEEEECCCCCCCCCCCHHHCCEEEEEE
AQPDSAAYNIPVALRVRGPLDVDALRAAFADAAAEHPALRARLVARDGALPGQRIDADVA
CCCCCCEEECCEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEE
VDLPVIDLSAQTDALARAAALTDEDALAPFDLTADAPLWRARVLRLGADDHVLSVTIHHI
EECEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEHHH
VSDGESIELWLDAVRARYVARMQRGAALVDEAVEPAAQPLVLPAPCHPARVAYWRDALAD
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHH
LPSRVLPQRTDAPAVPQWRAARIAFEFDTQLIRAARDAASASHATLPMLLHAALNTALFR
CHHHHCCCCCCCCCCCCCHHEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
ATGAADQPVGVLASTRELTGDAARTALGLFINSVVVRTRIDPAARRADVLAQVRDTALAA
CCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
YAHADVPFADVVAALRAPRAAQANPLFQVMFNYLRPTGAAARDWAGLSLAEFDDVRHRVV
HHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCEEEE
FTLELDVVEHPDGRVSAAFSYADELLARDFVEALVDLYHDEVARFAGASEAALGAPDAQA
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
AKPTSFDARANGATRPNATPSHAAAALAALWSDTFATAAPEPDADLFEAGATSFDVVRFV
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHH
DAAGRAGHALTVADVFAAPTLAALGARLDAHAETGQEARHAG
HHCCCCCCEEEHHHHHHHHHHHHHHHHHHCHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA