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The map label for this gene is yfmC [H]

Identifier: 116689660

GI number: 116689660

Start: 1805013

End: 1806038

Strand: Direct

Name: yfmC [H]

Synonym: Bcen2424_1638

Alternate gene names: 116689660

Gene position: 1805013-1806038 (Clockwise)

Preceding gene: 116689659

Following gene: 116689662

Centisome position: 51.81

GC content: 70.76

Gene sequence:

>1026_bases
GTGACGCACGCCGGCCGCCGGCACGCGCTCGGTGCACTCGCGGCAGCGCTTGGCGCCGCGTGCTGCGGCGCGTTTTCCGC
ATCGGCGGCGGCCGCCTCCGTGGCCGGGGGCGCGGGCGGTTCGCAACGCGCCGTGTCGCTGGCCGGCAATCCCGTCGTGT
CGCAGGCCAGCGCGAAGATGCCCGTGCGGCCGCAGCGCGTGGTCGCGCTCGACTTCATGTTCGCGGAAAGCGTGATCGCG
CTCGACCTCGTGCCGGTCGGGATGGCCGATACGGCGTTCTACCCAGGCTGGCTCGGTTATCGGAGCGAGCAGCTCGCGCA
CGTGACCGACATCGGCTCGCGGCAGGAGCCAGGGCTCGAGGCGATCGCGGCGGTCAAGCCGGATCTCATCATCGGCGTCG
GTTTCCGGCACGCGCCGATCTTCGACGCACTCGACCGGATCGCGCCGACGATCCTGTTCCAGTTCAGCCCGAACGTGTCG
GAAGACGGCGTGCCGGTCACGCAGCTCGACTGGATGCGGCAGATTTTCCGGACGATCGGCGCGGTGACGGGGCGCGACGC
GCGCGCGCAGGCGGTCGAAGCACAACTCGACGCCGGCATCGCGCGCAACGCGACGCGGCTCGCGGCCGCGGGCCGCCACG
GCGAGCGCGTCGCGCTGCTGCAGGATCTCGGCTTGCCCGATCGTTACTGGGCCTATACGGGCAACAGCACGTCGGCGGGC
CTCGCGCGAGCGCTCGGGCTCGAGCCGTGGCCGAAGAAGCCGACGCGGGAAGGCACGCTGTACGTGACGTCGGCCGATCT
GCTGCGGCAGCGCGACCTCGCCGTGCTGTTCGTGACCGCGTCGGGGATGGACGTGCCGTTGTCGGCGAAACTCGATTCGC
CGGTGTGGCGCTTCGTGCCCGCACTGAAAGATCACCGGATCGCGCTGATCGAGCGCAACATCTGGGGGTTCGGCGGGCCG
ATGTCGGCGCTGAAGCTGGCCGACGTGATGACCGACACGATGTTGAAGCTGCCGGCCGTGCGTTGA

Upstream 100 bases:

>100_bases
GCCTGCGCTACGAAATTCCTGGAGAAACGCAACTGTGTGGAAGCTGCCCCCTGCTACTGACGATGGACGACGCGGCGCTG
GCCGAGCAGGACGCGATCCG

Downstream 100 bases:

>100_bases
GCGCGGCGTGCTTCGAGCAGCAGGCGATGCCGCGTTGACGGGCAGGGCGTCGCGACCGGCCCGACGACGCGTGGCTTTCG
CCTTTCATTTTCGCCACACG

Product: periplasmic binding protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric-citrate-binding protein [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MTHAGRRHALGALAAALGAACCGAFSASAAAASVAGGAGGSQRAVSLAGNPVVSQASAKMPVRPQRVVALDFMFAESVIA
LDLVPVGMADTAFYPGWLGYRSEQLAHVTDIGSRQEPGLEAIAAVKPDLIIGVGFRHAPIFDALDRIAPTILFQFSPNVS
EDGVPVTQLDWMRQIFRTIGAVTGRDARAQAVEAQLDAGIARNATRLAAAGRHGERVALLQDLGLPDRYWAYTGNSTSAG
LARALGLEPWPKKPTREGTLYVTSADLLRQRDLAVLFVTASGMDVPLSAKLDSPVWRFVPALKDHRIALIERNIWGFGGP
MSALKLADVMTDTMLKLPAVR

Sequences:

>Translated_341_residues
MTHAGRRHALGALAAALGAACCGAFSASAAAASVAGGAGGSQRAVSLAGNPVVSQASAKMPVRPQRVVALDFMFAESVIA
LDLVPVGMADTAFYPGWLGYRSEQLAHVTDIGSRQEPGLEAIAAVKPDLIIGVGFRHAPIFDALDRIAPTILFQFSPNVS
EDGVPVTQLDWMRQIFRTIGAVTGRDARAQAVEAQLDAGIARNATRLAAAGRHGERVALLQDLGLPDRYWAYTGNSTSAG
LARALGLEPWPKKPTREGTLYVTSADLLRQRDLAVLFVTASGMDVPLSAKLDSPVWRFVPALKDHRIALIERNIWGFGGP
MSALKLADVMTDTMLKLPAVR
>Mature_340_residues
THAGRRHALGALAAALGAACCGAFSASAAAASVAGGAGGSQRAVSLAGNPVVSQASAKMPVRPQRVVALDFMFAESVIAL
DLVPVGMADTAFYPGWLGYRSEQLAHVTDIGSRQEPGLEAIAAVKPDLIIGVGFRHAPIFDALDRIAPTILFQFSPNVSE
DGVPVTQLDWMRQIFRTIGAVTGRDARAQAVEAQLDAGIARNATRLAAAGRHGERVALLQDLGLPDRYWAYTGNSTSAGL
ARALGLEPWPKKPTREGTLYVTSADLLRQRDLAVLFVTASGMDVPLSAKLDSPVWRFVPALKDHRIALIERNIWGFGGPM
SALKLADVMTDTMLKLPAVR

Specific function: Part of the ABC transporter complex yfmCDEF involved in citrate-dependent Fe(3+) import. Binds citrate-dependent Fe(3+) and delivers it to the surface of yfmDE (Probable) [H]

COG id: COG0614

COG function: function code P; ABC-type Fe3+-hydroxamate transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082411, Length=257, Percent_Identity=27.6264591439689, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786346, Length=276, Percent_Identity=26.4492753623188, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002491 [H]

Pfam domain/function: PF01497 Peripla_BP_2 [H]

EC number: NA

Molecular weight: Translated: 36084; Mature: 35953

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50983 FE_B12_PBP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHAGRRHALGALAAALGAACCGAFSASAAAASVAGGAGGSQRAVSLAGNPVVSQASAKM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCC
PVRPQRVVALDFMFAESVIALDLVPVGMADTAFYPGWLGYRSEQLAHVTDIGSRQEPGLE
CCCCCCEEEEHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHH
AIAAVKPDLIIGVGFRHAPIFDALDRIAPTILFQFSPNVSEDGVPVTQLDWMRQIFRTIG
HHHHCCCCEEEECCCCCCHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHC
AVTGRDARAQAVEAQLDAGIARNATRLAAAGRHGERVALLQDLGLPDRYWAYTGNSTSAG
CCCCCCHHHHHHHHHHHCCHHCCHHHHHHCCCCCCEEEEHHHCCCCCCEEEECCCCCHHH
LARALGLEPWPKKPTREGTLYVTSADLLRQRDLAVLFVTASGMDVPLSAKLDSPVWRFVP
HHHHHCCCCCCCCCCCCCEEEEEEHHHHHCCCEEEEEEEECCCCCCCCCCCCCHHHHHHH
ALKDHRIALIERNIWGFGGPMSALKLADVMTDTMLKLPAVR
HHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
THAGRRHALGALAAALGAACCGAFSASAAAASVAGGAGGSQRAVSLAGNPVVSQASAKM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCC
PVRPQRVVALDFMFAESVIALDLVPVGMADTAFYPGWLGYRSEQLAHVTDIGSRQEPGLE
CCCCCCEEEEHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHH
AIAAVKPDLIIGVGFRHAPIFDALDRIAPTILFQFSPNVSEDGVPVTQLDWMRQIFRTIG
HHHHCCCCEEEECCCCCCHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHC
AVTGRDARAQAVEAQLDAGIARNATRLAAAGRHGERVALLQDLGLPDRYWAYTGNSTSAG
CCCCCCHHHHHHHHHHHCCHHCCHHHHHHCCCCCCEEEEHHHCCCCCCEEEECCCCCHHH
LARALGLEPWPKKPTREGTLYVTSADLLRQRDLAVLFVTASGMDVPLSAKLDSPVWRFVP
HHHHHCCCCCCCCCCCCCEEEEEEHHHHHCCCEEEEEEEECCCCCCCCCCCCCHHHHHHH
ALKDHRIALIERNIWGFGGPMSALKLADVMTDTMLKLPAVR
HHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]