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The map label for this gene is alsB [H]

Identifier: 116689628

GI number: 116689628

Start: 1766511

End: 1767461

Strand: Direct

Name: alsB [H]

Synonym: Bcen2424_1606

Alternate gene names: 116689628

Gene position: 1766511-1767461 (Clockwise)

Preceding gene: 116689627

Following gene: 116689629

Centisome position: 50.7

GC content: 65.19

Gene sequence:

>951_bases
ATGAATGTCCGCTTTCGCCGTCGCTTCCTGACCGCCGCGCTCGCCGCCGTCGCGGTGGCCGCCGCACCGGCCGTCCACGC
GCAATCCGCGGCCAAGCCGAAGGTCGCGCTCGTGATGAAGTCGCTCGCCAACGAGTTCTTCCTGACCATGGAAACGGGCG
CGAAGGAATACCAGAAGCACAACGCGAACCAGTTCGACCTGATCACCAACGGCATCAAGGACGAGACCGACACCGCGAAC
CAGATCCGCATCGTCGAGCAGATGATCGTGTCGAAGGTCGATGCGATCGTGCTCGCGCCGGCCGATTCGAAGGCGCTCGT
GCCGGTCGTGAAGAAGGCCGTGGACGCCGGCATCGTCGTCGTGAACATCGACAACCGGCTCGATCCCGACGTGCTGAAGT
CGAAGAACCTGAACGTGCCGTTCGTCGGCCCGGACAATCGCAAGGGCGCGCGCAAGATCGGCGATTACCTCGCGAAGCGG
CTGAAGGCGGGCGACCAGGTCGGCATCGTCGAAGGCGTGTCGACGACGACCAACGCGCAGCAGCGCACGGCCGGCTTCCA
GGACGCGATGAAGGCGGGCGGAATGAAGGTCGTATCGGTGCAGTCGGGTGAATGGGAGATCGACAAGGGCAATGCGGTGG
CCGCCGCGATGCTCAACGAATACCCGAACCTGAAGGCGCTGCTGTGCGGCAACGACAACATGGCGATCGGCGCCGTGTCG
GCCGTGCGCGCGGCCGGCAAGCAGGGCAAGGTGCTCGTGGTCGGCTACGACAACATCAACGCGATCAAGCCGATGCTGAA
GGACGGCCGCGTGCTCGCGACCGCCGACCAGTACGCGGCGAAGCAGGCCGTGTTCGGCATCGACACCGCGCTCAAGGCGA
TCGCCGAGCATCGCAAGCAGGCCGACATGTCCGGCGTGGTCGAGACGCCGGTGGATCTCGTGACGAAGTAA

Upstream 100 bases:

>100_bases
CGATGGCCATTGCCCGGGTAGTGTGGCGCAAACGTTTGCTCACATTAAAACAACAGTCGAATAACAATCCGGCCTTCGGG
CCAGTCGCCAGGAGATGTGT

Downstream 100 bases:

>100_bases
CGCCGCGCCGATCCGGCCGCCGCCCTCAAGAATCCGGCGCGGCGGCCGTTATCCGGTGTGAGCGCGATCACGGCCACTGC
ATGCACATGCACTAGTGAGC

Product: periplasmic binding protein/LacI transcriptional regulator

Products: ADP; phosphate; ribose [Cytoplasm]; D-allose [Cytoplasm] [C]

Alternate protein names: ALBP [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MNVRFRRRFLTAALAAVAVAAAPAVHAQSAAKPKVALVMKSLANEFFLTMETGAKEYQKHNANQFDLITNGIKDETDTAN
QIRIVEQMIVSKVDAIVLAPADSKALVPVVKKAVDAGIVVVNIDNRLDPDVLKSKNLNVPFVGPDNRKGARKIGDYLAKR
LKAGDQVGIVEGVSTTTNAQQRTAGFQDAMKAGGMKVVSVQSGEWEIDKGNAVAAAMLNEYPNLKALLCGNDNMAIGAVS
AVRAAGKQGKVLVVGYDNINAIKPMLKDGRVLATADQYAAKQAVFGIDTALKAIAEHRKQADMSGVVETPVDLVTK

Sequences:

>Translated_316_residues
MNVRFRRRFLTAALAAVAVAAAPAVHAQSAAKPKVALVMKSLANEFFLTMETGAKEYQKHNANQFDLITNGIKDETDTAN
QIRIVEQMIVSKVDAIVLAPADSKALVPVVKKAVDAGIVVVNIDNRLDPDVLKSKNLNVPFVGPDNRKGARKIGDYLAKR
LKAGDQVGIVEGVSTTTNAQQRTAGFQDAMKAGGMKVVSVQSGEWEIDKGNAVAAAMLNEYPNLKALLCGNDNMAIGAVS
AVRAAGKQGKVLVVGYDNINAIKPMLKDGRVLATADQYAAKQAVFGIDTALKAIAEHRKQADMSGVVETPVDLVTK
>Mature_316_residues
MNVRFRRRFLTAALAAVAVAAAPAVHAQSAAKPKVALVMKSLANEFFLTMETGAKEYQKHNANQFDLITNGIKDETDTAN
QIRIVEQMIVSKVDAIVLAPADSKALVPVVKKAVDAGIVVVNIDNRLDPDVLKSKNLNVPFVGPDNRKGARKIGDYLAKR
LKAGDQVGIVEGVSTTTNAQQRTAGFQDAMKAGGMKVVSVQSGEWEIDKGNAVAAAMLNEYPNLKALLCGNDNMAIGAVS
AVRAAGKQGKVLVVGYDNINAIKPMLKDGRVLATADQYAAKQAVFGIDTALKAIAEHRKQADMSGVVETPVDLVTK

Specific function: Part of the binding-protein-dependent transport system AlsBAC for D-allose [H]

COG id: COG1879

COG function: function code G; ABC-type sugar transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790526, Length=260, Percent_Identity=34.6153846153846, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1790192, Length=297, Percent_Identity=31.3131313131313, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1790674, Length=205, Percent_Identity=33.6585365853659, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1788898, Length=315, Percent_Identity=27.3015873015873, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001761 [H]

Pfam domain/function: PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 33576; Mature: 33576

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVRFRRRFLTAALAAVAVAAAPAVHAQSAAKPKVALVMKSLANEFFLTMETGAKEYQKH
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHEEEEECCCHHHHHHC
NANQFDLITNGIKDETDTANQIRIVEQMIVSKVDAIVLAPADSKALVPVVKKAVDAGIVV
CCCEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHCCEEE
VNIDNRLDPDVLKSKNLNVPFVGPDNRKGARKIGDYLAKRLKAGDQVGIVEGVSTTTNAQ
EEECCCCCHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHH
QRTAGFQDAMKAGGMKVVSVQSGEWEIDKGNAVAAAMLNEYPNLKALLCGNDNMAIGAVS
HHHCCHHHHHHHCCEEEEEEECCCEEECCCCCHHHHHHHCCCCCEEEEECCCCCEEHHHH
AVRAAGKQGKVLVVGYDNINAIKPMLKDGRVLATADQYAAKQAVFGIDTALKAIAEHRKQ
HHHHCCCCCCEEEEECCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
ADMSGVVETPVDLVTK
CCCCCCHHCCHHHHCC
>Mature Secondary Structure
MNVRFRRRFLTAALAAVAVAAAPAVHAQSAAKPKVALVMKSLANEFFLTMETGAKEYQKH
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHEEEEECCCHHHHHHC
NANQFDLITNGIKDETDTANQIRIVEQMIVSKVDAIVLAPADSKALVPVVKKAVDAGIVV
CCCEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHCCEEE
VNIDNRLDPDVLKSKNLNVPFVGPDNRKGARKIGDYLAKRLKAGDQVGIVEGVSTTTNAQ
EEECCCCCHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHH
QRTAGFQDAMKAGGMKVVSVQSGEWEIDKGNAVAAAMLNEYPNLKALLCGNDNMAIGAVS
HHHCCHHHHHHHCCEEEEEEECCCEEECCCCCHHHHHHHCCCCCEEEEECCCCCEEHHHH
AVRAAGKQGKVLVVGYDNINAIKPMLKDGRVLATADQYAAKQAVFGIDTALKAIAEHRKQ
HHHHCCCCCCEEEEECCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
ADMSGVVETPVDLVTK
CCCCCCHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; ribose [Periplasm]; D-allose [Periplasm]; ATP [C]

Specific reaction: ATP + H2O + ribose [Periplasm] = ADP + phosphate + ribose [Cytoplasm] D-allose [Periplasm] + ATP + H2O = D-allose [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 8576032; 9401019; 10064713 [H]