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The map label for this gene is cbl [H]

Identifier: 116689627

GI number: 116689627

Start: 1764844

End: 1765770

Strand: Direct

Name: cbl [H]

Synonym: Bcen2424_1605

Alternate gene names: 116689627

Gene position: 1764844-1765770 (Clockwise)

Preceding gene: 116689626

Following gene: 116689628

Centisome position: 50.66

GC content: 65.26

Gene sequence:

>927_bases
ATGAATTTTCAGCAATTGCGGTTCGTGCGCGAAGCGGTGCGCCAGAACATGAACCTGACGGAAGTCGCGAACGTGCTGTA
CACGTCGCAGTCGGGCGTGTCGAAACAGATCAAGGATCTGGAAGATGAGCTGGGCGTCGACATCTTCATTCGGCGCGGCA
AGCGGCTGACGGGGCTCACCGAGCCCGGCAAGGCGGTGCACCAGCTGATCGAGCGGATGCTGCTCGACGCCGAGAATCTG
CGCCGCGTCGCGCGCCAGTTCGCCGATCAGGACAGCGGCCACCTCGTCGTCGCGACGACGCACACGCAGGCGCGCTACGC
GTTGCCGAAGGTGATCCGGCAGTTCACCGACGTGTTCCCGAAGGTGCATCTCGCGCTGCGCCAGGGCAGCCCGCAGCAGA
TCGCGCAGATGATCCTGAACGGCGAGGCCGATCTGGGCATCTCGACCGAGGCGCTCGACCGTTATCCGGACATCGTCACG
TTCCCGTGCTATTCGTGGCACCACACGGTCGTCGTGCCGAAGGGCCATCCGCTCGTCGGCCGCGCGAACCTGACGCTCGA
GGAAATCGCCGAGTACCCGATCATCACGTACGACCAGGACTTCACGGGCCGTTCGCACATCGACCAGGCGTTCACGCAGG
CGGGCGCCGTGCCCGACGTCGTGCTGACCGCGATCGACGCGGACGTGATCAAGACCTACGTCGAACTCGGGATGGGGATC
GGCGTGGTCGCGGCGATGGCCTACGATCCGCAGCGCGACACGGGGCTCGTCGCGCTCGATACGCAACACCTGTTCGAGGC
GAGCACGACGCGGGTCGGGCTGCGCAAGGGCGCGTTCCTGCGTGCGTATGCGTACCGGCTGATCGAAATGTTCGCGCCGC
ACCTGAACGAAGCGGAAATCGCGGGGCTGTTGCGCGAAGCCGTTTGA

Upstream 100 bases:

>100_bases
CGTGCGGGTATTTCCCGCGCGTTGACGAGACAAAGCAGGGCAGAGGGCGGGTTTCGCTCCGATTGAACAATCAAACAACG
ACAGCCTAAGAGGCATACCC

Downstream 100 bases:

>100_bases
TTTGACCCGAGCGTGTCGCGCGCCGTCCGGGCCATTGCCGCGGATGGCGCGACTTGCACCACGTGTGCGTTGCCGCATAC
GGCACCGGGCGGCGGCAGGG

Product: transcriptional regulator CysB-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFIRRGKRLTGLTEPGKAVHQLIERMLLDAENL
RRVARQFADQDSGHLVVATTHTQARYALPKVIRQFTDVFPKVHLALRQGSPQQIAQMILNGEADLGISTEALDRYPDIVT
FPCYSWHHTVVVPKGHPLVGRANLTLEEIAEYPIITYDQDFTGRSHIDQAFTQAGAVPDVVLTAIDADVIKTYVELGMGI
GVVAAMAYDPQRDTGLVALDTQHLFEASTTRVGLRKGAFLRAYAYRLIEMFAPHLNEAEIAGLLREAV

Sequences:

>Translated_308_residues
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFIRRGKRLTGLTEPGKAVHQLIERMLLDAENL
RRVARQFADQDSGHLVVATTHTQARYALPKVIRQFTDVFPKVHLALRQGSPQQIAQMILNGEADLGISTEALDRYPDIVT
FPCYSWHHTVVVPKGHPLVGRANLTLEEIAEYPIITYDQDFTGRSHIDQAFTQAGAVPDVVLTAIDADVIKTYVELGMGI
GVVAAMAYDPQRDTGLVALDTQHLFEASTTRVGLRKGAFLRAYAYRLIEMFAPHLNEAEIAGLLREAV
>Mature_308_residues
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFIRRGKRLTGLTEPGKAVHQLIERMLLDAENL
RRVARQFADQDSGHLVVATTHTQARYALPKVIRQFTDVFPKVHLALRQGSPQQIAQMILNGEADLGISTEALDRYPDIVT
FPCYSWHHTVVVPKGHPLVGRANLTLEEIAEYPIITYDQDFTGRSHIDQAFTQAGAVPDVVLTAIDADVIKTYVELGMGI
GVVAAMAYDPQRDTGLVALDTQHLFEASTTRVGLRKGAFLRAYAYRLIEMFAPHLNEAEIAGLLREAV

Specific function: May be an accessory regulatory protein within the cys regulon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788296, Length=300, Percent_Identity=54.6666666666667, Blast_Score=347, Evalue=4e-97,
Organism=Escherichia coli, GI1787530, Length=296, Percent_Identity=50, Blast_Score=316, Evalue=2e-87,
Organism=Escherichia coli, GI157672245, Length=225, Percent_Identity=29.7777777777778, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788887, Length=259, Percent_Identity=28.957528957529, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788481, Length=258, Percent_Identity=25.5813953488372, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790399, Length=290, Percent_Identity=24.1379310344828, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI2367136, Length=241, Percent_Identity=24.4813278008299, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787806, Length=243, Percent_Identity=23.0452674897119, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789204, Length=246, Percent_Identity=24.7967479674797, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082132, Length=122, Percent_Identity=34.4262295081967, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790262, Length=256, Percent_Identity=23.828125, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790208, Length=224, Percent_Identity=26.7857142857143, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787601, Length=185, Percent_Identity=27.5675675675676, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34365; Mature: 34365

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFIRRGKRLTGLT
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCC
EPGKAVHQLIERMLLDAENLRRVARQFADQDSGHLVVATTHTQARYALPKVIRQFTDVFP
CCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
KVHLALRQGSPQQIAQMILNGEADLGISTEALDRYPDIVTFPCYSWHHTVVVPKGHPLVG
HHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHCCCEEEECCCCCCEEEEEECCCCCEE
RANLTLEEIAEYPIITYDQDFTGRSHIDQAFTQAGAVPDVVLTAIDADVIKTYVELGMGI
CCCCCHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCH
GVVAAMAYDPQRDTGLVALDTQHLFEASTTRVGLRKGAFLRAYAYRLIEMFAPHLNEAEI
HHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHH
AGLLREAV
HHHHHHCC
>Mature Secondary Structure
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFIRRGKRLTGLT
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCC
EPGKAVHQLIERMLLDAENLRRVARQFADQDSGHLVVATTHTQARYALPKVIRQFTDVFP
CCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
KVHLALRQGSPQQIAQMILNGEADLGISTEALDRYPDIVTFPCYSWHHTVVVPKGHPLVG
HHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHCCCEEEECCCCCCEEEEEECCCCCEE
RANLTLEEIAEYPIITYDQDFTGRSHIDQAFTQAGAVPDVVLTAIDADVIKTYVELGMGI
CCCCCHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCH
GVVAAMAYDPQRDTGLVALDTQHLFEASTTRVGLRKGAFLRAYAYRLIEMFAPHLNEAEI
HHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHH
AGLLREAV
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8529872; 9097040; 9278503 [H]