Click here to switch to the map view.

The map label for this gene is rpiA

Identifier: 116689571

GI number: 116689571

Start: 1715796

End: 1716491

Strand: Direct

Name: rpiA

Synonym: Bcen2424_1549

Alternate gene names: 116689571

Gene position: 1715796-1716491 (Clockwise)

Preceding gene: 116689570

Following gene: 116689572

Centisome position: 49.25

GC content: 66.95

Gene sequence:

>696_bases
ATGACTCAAGACGAACTCAAACGCCTCGTCGGCCAGGCCGCCGCCGATTACGTGATCCAGAACGTGCCGGAAGGCGCCGT
GATCGGTGTCGGCACCGGCTCGACCGCCAACTGCTTCATCGACGCGCTCGCCGCCGTCAAATCGCGCTACCGCGGCGCCG
TGTCGAGCTCGATTGCCACGACCGAACGCCTGAAATCGCACGGCATCAAGGTGTTCGACCTGAACGAGATCGAGTCGCTG
CAGGTGTACGTCGACGGCGCCGACGAGATCGACGCGGGCGGCGCGATGATCAAGGGCGGCGGCGGCGCGCTGACGCGCGA
GAAGATCGTCGCATCGGTGGCCGACACGTTCGTCTGCATCGCGGACGCCAGCAAGCGCGTGCCGGTGCTCGGCGCGTTCC
CGCTGCCGATCGAGGTCGTGCCGATGGCGCGCACGGCGATCGGCCGGCGCGTGACCGCGCTCGGCGGCGTGCCCGTGCTG
CGCGTGACGAAGGACGGCGCGCCCTACATCACCGACAACGGCAACGAGATCATCGACGTGAAGGGCCTGCAGATCGCCGA
TCCGCGCGGTTTCGAAGCGCAGGTGAACGCATGGCCGGGCGTCGTGACGGTCGGTCTGTTCGCCGAACGCGGCGCGAATC
TGTGCTTGCTTGGCACGGAAAACGGCGTTGAAACGATCGTTTATCCGGCTGGCTAA

Upstream 100 bases:

>100_bases
CACCCTGAATACGCGGCGCGGCGCACGCCGAAAAACGCGGGGACGTCCGCCGACTCCGGTAAACTGGCGGTTTTCCGCAA
TCCCGCAGCATTACCACGCC

Downstream 100 bases:

>100_bases
AACTGAATGAGAAGCAGTCCGTAACGGCGCGGTATCGGCCGTCATGGATTGGATGGTTAAATCTTGTGGAAACCGGGGTC
CGGCAGGCGCGGCGCGCTTC

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MTQDELKRLVGQAAADYVIQNVPEGAVIGVGTGSTANCFIDALAAVKSRYRGAVSSSIATTERLKSHGIKVFDLNEIESL
QVYVDGADEIDAGGAMIKGGGGALTREKIVASVADTFVCIADASKRVPVLGAFPLPIEVVPMARTAIGRRVTALGGVPVL
RVTKDGAPYITDNGNEIIDVKGLQIADPRGFEAQVNAWPGVVTVGLFAERGANLCLLGTENGVETIVYPAG

Sequences:

>Translated_231_residues
MTQDELKRLVGQAAADYVIQNVPEGAVIGVGTGSTANCFIDALAAVKSRYRGAVSSSIATTERLKSHGIKVFDLNEIESL
QVYVDGADEIDAGGAMIKGGGGALTREKIVASVADTFVCIADASKRVPVLGAFPLPIEVVPMARTAIGRRVTALGGVPVL
RVTKDGAPYITDNGNEIIDVKGLQIADPRGFEAQVNAWPGVVTVGLFAERGANLCLLGTENGVETIVYPAG
>Mature_230_residues
TQDELKRLVGQAAADYVIQNVPEGAVIGVGTGSTANCFIDALAAVKSRYRGAVSSSIATTERLKSHGIKVFDLNEIESLQ
VYVDGADEIDAGGAMIKGGGGALTREKIVASVADTFVCIADASKRVPVLGAFPLPIEVVPMARTAIGRRVTALGGVPVLR
VTKDGAPYITDNGNEIIDVKGLQIADPRGFEAQVNAWPGVVTVGLFAERGANLCLLGTENGVETIVYPAG

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=221, Percent_Identity=36.6515837104072, Blast_Score=114, Evalue=6e-26,
Organism=Escherichia coli, GI1789280, Length=227, Percent_Identity=61.2334801762115, Blast_Score=266, Evalue=6e-73,
Organism=Caenorhabditis elegans, GI17551758, Length=200, Percent_Identity=38, Blast_Score=100, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6324669, Length=237, Percent_Identity=27.4261603375527, Blast_Score=85, Evalue=9e-18,
Organism=Drosophila melanogaster, GI281364072, Length=211, Percent_Identity=35.0710900473934, Blast_Score=98, Evalue=5e-21,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_BURCA (Q1BWM9)

Other databases:

- EMBL:   CP000378
- RefSeq:   YP_620949.1
- ProteinModelPortal:   Q1BWM9
- SMR:   Q1BWM9
- STRING:   Q1BWM9
- GeneID:   4092173
- GenomeReviews:   CP000378_GR
- KEGG:   bcn:Bcen_1069
- eggNOG:   COG0120
- HOGENOM:   HBG515603
- OMA:   VFDLNSV
- ProtClustDB:   PRK00702
- BioCyc:   BCEN331271:BCEN_1069-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 23967; Mature: 23836

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDELKRLVGQAAADYVIQNVPEGAVIGVGTGSTANCFIDALAAVKSRYRGAVSSSIAT
CCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
TERLKSHGIKVFDLNEIESLQVYVDGADEIDAGGAMIKGGGGALTREKIVASVADTFVCI
HHHHHHCCCEEEECCCCCEEEEEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHEEEE
ADASKRVPVLGAFPLPIEVVPMARTAIGRRVTALGGVPVLRVTKDGAPYITDNGNEIIDV
ECCCCCCCEEECCCCCEEEECHHHHHHCCEEEECCCCEEEEEECCCCCEEECCCCEEEEE
KGLQIADPRGFEAQVNAWPGVVTVGLFAERGANLCLLGTENGVETIVYPAG
CCEEEECCCCCEEEECCCCCEEEEEEHHHCCCCEEEEECCCCCEEEEEECC
>Mature Secondary Structure 
TQDELKRLVGQAAADYVIQNVPEGAVIGVGTGSTANCFIDALAAVKSRYRGAVSSSIAT
CHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
TERLKSHGIKVFDLNEIESLQVYVDGADEIDAGGAMIKGGGGALTREKIVASVADTFVCI
HHHHHHCCCEEEECCCCCEEEEEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHEEEE
ADASKRVPVLGAFPLPIEVVPMARTAIGRRVTALGGVPVLRVTKDGAPYITDNGNEIIDV
ECCCCCCCEEECCCCCEEEECHHHHHHCCEEEECCCCEEEEEECCCCCEEECCCCEEEEE
KGLQIADPRGFEAQVNAWPGVVTVGLFAERGANLCLLGTENGVETIVYPAG
CCEEEECCCCCEEEECCCCCEEEEEEHHHCCCCEEEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA