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The map label for this gene is mdtP [H]

Identifier: 116689527

GI number: 116689527

Start: 1661185

End: 1662681

Strand: Reverse

Name: mdtP [H]

Synonym: Bcen2424_1505

Alternate gene names: 116689527

Gene position: 1662681-1661185 (Counterclockwise)

Preceding gene: 116689528

Following gene: 116689526

Centisome position: 47.72

GC content: 68.27

Gene sequence:

>1497_bases
ATGAAAACCTCCCCGTTGTCCGTGCGCGCCGGGTCGTGCCGTGCCGCCGTCGCCGCCGCGGTCGCCGCGCTGGCGCTGGC
GGGCTGCGCGAATTACATCGGCATCAAGAGCGACAAGCAGATCGCCCCCGCGTCGCAATTCGAATCCGCCCAGAGCCTGC
CGGCCCAGGGCGGCCAGTGGCCGGCGCTCGACTGGGCCAACCAGTTCGGCGATCCGCAACTGCCGAAGCTGATCGACGAA
GCGCTGCAGGGCAACCCGTCGATCGCGCAGGCCCAGGCGCGCATCGCGAAAGCCTCGTCGTACATCGAATCGTCCCGCTC
GAACCTGATGCCGAAGGCCGAAGCCAGCTATTCGTGGACGCGCGAGCTGTATTCGTCGAACGCACTGTTCCCGCCCCCGT
ACGGCGGCCAGTGGTACAGCGAGAACAATGTGCTCGCAAGCGCCTCGTGGGAACTCGATCTGTGGGGCAAGAACCGCGAA
CGCCTGCACACGGCCGTATCGCAGGAAAAAGCCGCCGAAGCCGACATGCAACAGGCGCGCATCACGCTCGCATCGTCGGT
CGCGCGCACTTACAACTCGCTCGCGCAACTCTATGCGCTGCGGGACATCGCGCAGCGCGAGATCACCAACCGCGAGACGG
TCGGCAAGATCACCGACGGCCGCGTATCGGCCGGCCTCGACACCAACGTCGAGCGCCAGACGGCCCGCGGCAACATCGCG
ACGACCCAGGCTTCGCTGTCGGACCTCGACGGGCAGATCACGACGGTGCGCTACCAGCTCGCCGCGCTGCTCGGCAAAGG
CCCGGATCGCGGGCTGCAGATTGCGGCGCCCGTGCTGAACCCGAGCGGCGACGTCACGCTGCCCGGCAACCTGCCGGCCG
ATCTCGTGTCGCGCCGCCCCGACATCGTCGCCGCGCGCTGGCAGGTCGAAGCCGCGATGCACGACGTGAAGGAAGCGAAG
GCCGAGTTCTACCCCGACGTGAACCTCGCGGCCGGCTTCGGCTTCGATGCGTTCGGCTGGGGCAAATTCCTGAACTTCGC
GAGCCGCCAGGCGCAGTTCGGCCCGGCGATCCACCTCCCGATCTTCGATGCCGGCGCGCTGCGCGCCCAGCTCAAGGGCC
GCTACGCCGACTTCGACCTGTCGGTCGCGAACTACAACCAGACGCTGATCAGCGCGCTGAACGACGTCGCGACGCAGGTC
GCGTCGATCCGCGCAATCGATCGGCAGATGGGCGACGCCCAACGTGCGCTCGACGCATCGACGCGCGCGTACGATCTCGC
GGTCATTCGCTACAAGGCCGGCCTGTCGCCGCAACTGCAGGTGCTGACGGCGGACAGCAACCGCCTCGCATCGGAGCAGA
CGGTGACCAACCTGAAGATGCGTCGCCGCGACATGCAGCTCGCGCTGATCAAGGCGCTCGGCGGCGGGTTCGACGCAACC
GGCACGCCGCTCGCCGCGCCCGATGCCGCCACGCCGACCAAACAGGCCGCCAACTGA

Upstream 100 bases:

>100_bases
TAGCATCACGTAATAGTTGCCATAACAATTACTTTTGACAGATTAATGTAAGGAAATCCTTGCAGTGTCCATCATTCATT
CCGAGTCAGGGGTTAGCGCG

Downstream 100 bases:

>100_bases
GCCGGCGCCACCACTACGCAGACACTCGAAATAACGGACGGAGAAAATCGCCATGAGCGACCAACAAAACGCCGCCAGCG
CGCAGCCGCAGAACAACGGC

Product: RND efflux system outer membrane lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MKTSPLSVRAGSCRAAVAAAVAALALAGCANYIGIKSDKQIAPASQFESAQSLPAQGGQWPALDWANQFGDPQLPKLIDE
ALQGNPSIAQAQARIAKASSYIESSRSNLMPKAEASYSWTRELYSSNALFPPPYGGQWYSENNVLASASWELDLWGKNRE
RLHTAVSQEKAAEADMQQARITLASSVARTYNSLAQLYALRDIAQREITNRETVGKITDGRVSAGLDTNVERQTARGNIA
TTQASLSDLDGQITTVRYQLAALLGKGPDRGLQIAAPVLNPSGDVTLPGNLPADLVSRRPDIVAARWQVEAAMHDVKEAK
AEFYPDVNLAAGFGFDAFGWGKFLNFASRQAQFGPAIHLPIFDAGALRAQLKGRYADFDLSVANYNQTLISALNDVATQV
ASIRAIDRQMGDAQRALDASTRAYDLAVIRYKAGLSPQLQVLTADSNRLASEQTVTNLKMRRRDMQLALIKALGGGFDAT
GTPLAAPDAATPTKQAAN

Sequences:

>Translated_498_residues
MKTSPLSVRAGSCRAAVAAAVAALALAGCANYIGIKSDKQIAPASQFESAQSLPAQGGQWPALDWANQFGDPQLPKLIDE
ALQGNPSIAQAQARIAKASSYIESSRSNLMPKAEASYSWTRELYSSNALFPPPYGGQWYSENNVLASASWELDLWGKNRE
RLHTAVSQEKAAEADMQQARITLASSVARTYNSLAQLYALRDIAQREITNRETVGKITDGRVSAGLDTNVERQTARGNIA
TTQASLSDLDGQITTVRYQLAALLGKGPDRGLQIAAPVLNPSGDVTLPGNLPADLVSRRPDIVAARWQVEAAMHDVKEAK
AEFYPDVNLAAGFGFDAFGWGKFLNFASRQAQFGPAIHLPIFDAGALRAQLKGRYADFDLSVANYNQTLISALNDVATQV
ASIRAIDRQMGDAQRALDASTRAYDLAVIRYKAGLSPQLQVLTADSNRLASEQTVTNLKMRRRDMQLALIKALGGGFDAT
GTPLAAPDAATPTKQAAN
>Mature_498_residues
MKTSPLSVRAGSCRAAVAAAVAALALAGCANYIGIKSDKQIAPASQFESAQSLPAQGGQWPALDWANQFGDPQLPKLIDE
ALQGNPSIAQAQARIAKASSYIESSRSNLMPKAEASYSWTRELYSSNALFPPPYGGQWYSENNVLASASWELDLWGKNRE
RLHTAVSQEKAAEADMQQARITLASSVARTYNSLAQLYALRDIAQREITNRETVGKITDGRVSAGLDTNVERQTARGNIA
TTQASLSDLDGQITTVRYQLAALLGKGPDRGLQIAAPVLNPSGDVTLPGNLPADLVSRRPDIVAARWQVEAAMHDVKEAK
AEFYPDVNLAAGFGFDAFGWGKFLNFASRQAQFGPAIHLPIFDAGALRAQLKGRYADFDLSVANYNQTLISALNDVATQV
ASIRAIDRQMGDAQRALDASTRAYDLAVIRYKAGLSPQLQVLTADSNRLASEQTVTNLKMRRRDMQLALIKALGGGFDAT
GTPLAAPDAATPTKQAAN

Specific function: Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI2367348, Length=465, Percent_Identity=31.1827956989247, Blast_Score=198, Evalue=7e-52,
Organism=Escherichia coli, GI1786785, Length=466, Percent_Identity=27.6824034334764, Blast_Score=129, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 53380; Mature: 53380

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTSPLSVRAGSCRAAVAAAVAALALAGCANYIGIKSDKQIAPASQFESAQSLPAQGGQW
CCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCC
PALDWANQFGDPQLPKLIDEALQGNPSIAQAQARIAKASSYIESSRSNLMPKAEASYSWT
CCCHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
RELYSSNALFPPPYGGQWYSENNVLASASWELDLWGKNRERLHTAVSQEKAAEADMQQAR
HHHHCCCCCCCCCCCCCCCCCCCEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
ITLASSVARTYNSLAQLYALRDIAQREITNRETVGKITDGRVSAGLDTNVERQTARGNIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEECCCCCCCHHHHCCCCCE
TTQASLSDLDGQITTVRYQLAALLGKGPDRGLQIAAPVLNPSGDVTLPGNLPADLVSRRP
ECHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEECCCCCHHHHHCCC
DIVAARWQVEAAMHDVKEAKAEFYPDVNLAAGFGFDAFGWGKFLNFASRQAQFGPAIHLP
CEEEEHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEE
IFDAGALRAQLKGRYADFDLSVANYNQTLISALNDVATQVASIRAIDRQMGDAQRALDAS
ECCCHHHHHHHCCCCCCEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TRAYDLAVIRYKAGLSPQLQVLTADSNRLASEQTVTNLKMRRRDMQLALIKALGGGFDAT
CCCEEEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GTPLAAPDAATPTKQAAN
CCCCCCCCCCCCCHHCCC
>Mature Secondary Structure
MKTSPLSVRAGSCRAAVAAAVAALALAGCANYIGIKSDKQIAPASQFESAQSLPAQGGQW
CCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCC
PALDWANQFGDPQLPKLIDEALQGNPSIAQAQARIAKASSYIESSRSNLMPKAEASYSWT
CCCHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
RELYSSNALFPPPYGGQWYSENNVLASASWELDLWGKNRERLHTAVSQEKAAEADMQQAR
HHHHCCCCCCCCCCCCCCCCCCCEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
ITLASSVARTYNSLAQLYALRDIAQREITNRETVGKITDGRVSAGLDTNVERQTARGNIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEECCCCCCCHHHHCCCCCE
TTQASLSDLDGQITTVRYQLAALLGKGPDRGLQIAAPVLNPSGDVTLPGNLPADLVSRRP
ECHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEECCCCCHHHHHCCC
DIVAARWQVEAAMHDVKEAKAEFYPDVNLAAGFGFDAFGWGKFLNFASRQAQFGPAIHLP
CEEEEHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEE
IFDAGALRAQLKGRYADFDLSVANYNQTLISALNDVATQVASIRAIDRQMGDAQRALDAS
ECCCHHHHHHHCCCCCCEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TRAYDLAVIRYKAGLSPQLQVLTADSNRLASEQTVTNLKMRRRDMQLALIKALGGGFDAT
CCCEEEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GTPLAAPDAATPTKQAAN
CCCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]