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The map label for this gene is glnS [H]

Identifier: 116689427

GI number: 116689427

Start: 1549382

End: 1551091

Strand: Reverse

Name: glnS [H]

Synonym: Bcen2424_1405

Alternate gene names: 116689427

Gene position: 1551091-1549382 (Counterclockwise)

Preceding gene: 116689430

Following gene: 116689423

Centisome position: 44.52

GC content: 64.39

Gene sequence:

>1710_bases
ATGAGCACCGAACGCAACGACGCCCCCGCGGCTTCCAATTTCATCCGCAACATCATCGACGACGACAACCGCACCGGCAA
ATGGGGCGGCCGCGTCGAAACGCGCTTCCCGCCCGAGCCGAACGGCTATCTGCACATCGGTCACGCGAAGAGCATCTGCC
TGAACTTCAGCGTCGCGCGCGACTACGGCGGCGTGTGCCACCTGCGCTTCGACGACACGAACCCGGAAAAGGAAAGCGTC
GAATACGTCGACTCGATCGTCGACGCGGTGCGCTGGCTCGGCTTCGACTGGCGCAAGGACGCGGTCGATCACCAGTATTT
CGCGAGCGACTACTACGACAAGCTGTACGAGTTCGCCGAGCTGCTGATCCAGCGCGGCAAGGCTTACGTCGACAGCCAGA
GCGCCGACGAAATGCGCGCGAACCGCGGCTCGCTGACCGAAGGCGGCAAGCCGTCGCCGTTCCGCGATCGCACGCCGGCA
GAAAACCTCGACCTGTTCCGCCGCATGAAGGCCGGCGAGTTCAAGGAAGGCGAGCACGTGCTGCGCGCGAAGATCGACAT
GGCGTCGCCGAACATGAACATGCGCGACCCGGTGATCTACCGGATCCGCTACGCGCACCATTACCGCACCGGCGACGCAT
GGTGCGTGTATCCGATGTACGACTACACGCACTGCATCTCGGATGCGCTCGAAGGCATCACGCATTCGCTGTGCACGCTC
GAATTCGAGGATCATCGCCCGCTGTACGACTGGGTGCTGAACGAACTCGCGGAAGCCGGCGTGTTCACGCGCCCGCTGCC
GCAACAGATCGAATTCTCGCGGCTGAACCTCACGTACGCGATCACCAGCAAGCGCAAGCTGCTGCAGCTCGTCACCGAAG
GCCACGTCGACGGCTGGGACGACCCGCGGATGCCGACGATCGTCGGCGTGCGCCGCCGCGGCTTCACGCCCGAAAGCATT
CACCTGTTCTGCGAGCGGATCGGCGTGACGAAGATCGATTCGTGGATCGACATGAGCATCTTCGAAGGCGCGCTGCGCGA
CGACCTCGACGACAAGGCCGCGCGTACGGTCGCGGTGCTCGATCCGCTGAAGCTCGTGATCGACAACTATCCGGAAGACC
TCGAGGAAGCGTGCACGGCGCCCGTGCATCCGCACCATCCGGACCGCGGCGTGCGCACGTTCCCGATCTCGCGCGAGCTG
TGGATCGAGCGCGAGGACTTCGTCGAGAATCCGCCGAAGGGCTATTTCCGACTGTTCCCGGGCAACAAGGTGCGCCTGCG
CTACGGCTACGTGATCGAGTGCACGGGCTTCGACAAGGACGCCGACGGCAACGTGACGGCCGTGCACTGCAACTACTTCC
CGGACAGCAAGTCGGGCACCGAAGGCGCGAACACGTACAAGGTCAAGGGCAACATCCACTGGGTCAGCGCGAAGCACGCG
CAGCCGGCCGAAGTGCGGATCTACGACCGCCTGTTCAAGGAGCCGCACCCGGACGCGGGCGGCGCGAACTTCCTCGAAGC
GCTGAACCCCGATTCGAAAAAGATCGTGCAGGCATACCTCGAGCCGGGCAACGGCGACGTCGCGCCGGAAACGCGCCTGC
AGTTCGAGCGCCACGGCTACTTTGTTGCAGACCGTGTCGATTCGAAACCGGGCAAGCCGGTGTTCAACCGGATCGTCGGG
CTGCGCGACAGCTGGGGCAAGCCGGCCTGA

Upstream 100 bases:

>100_bases
ACGGCAGCCGACCGGCAGGCCGCGCGGGACGGACCCCGGTCAGGTAGAATTACAGGATTAAACCGGCGCGACGCGCCGAC
ACAACCCTGACGCCAACCGC

Downstream 100 bases:

>100_bases
CGGCCTGCTGCACGCGGCGGCGTGCGGCTTCGCAAGCCGCCCCGCTGCCTGCCCATGAAAAAAACCGGCTCGAGGGCCGG
TTTTTTTATCGGCGTGCGCC

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MSTERNDAPAASNFIRNIIDDDNRTGKWGGRVETRFPPEPNGYLHIGHAKSICLNFSVARDYGGVCHLRFDDTNPEKESV
EYVDSIVDAVRWLGFDWRKDAVDHQYFASDYYDKLYEFAELLIQRGKAYVDSQSADEMRANRGSLTEGGKPSPFRDRTPA
ENLDLFRRMKAGEFKEGEHVLRAKIDMASPNMNMRDPVIYRIRYAHHYRTGDAWCVYPMYDYTHCISDALEGITHSLCTL
EFEDHRPLYDWVLNELAEAGVFTRPLPQQIEFSRLNLTYAITSKRKLLQLVTEGHVDGWDDPRMPTIVGVRRRGFTPESI
HLFCERIGVTKIDSWIDMSIFEGALRDDLDDKAARTVAVLDPLKLVIDNYPEDLEEACTAPVHPHHPDRGVRTFPISREL
WIEREDFVENPPKGYFRLFPGNKVRLRYGYVIECTGFDKDADGNVTAVHCNYFPDSKSGTEGANTYKVKGNIHWVSAKHA
QPAEVRIYDRLFKEPHPDAGGANFLEALNPDSKKIVQAYLEPGNGDVAPETRLQFERHGYFVADRVDSKPGKPVFNRIVG
LRDSWGKPA

Sequences:

>Translated_569_residues
MSTERNDAPAASNFIRNIIDDDNRTGKWGGRVETRFPPEPNGYLHIGHAKSICLNFSVARDYGGVCHLRFDDTNPEKESV
EYVDSIVDAVRWLGFDWRKDAVDHQYFASDYYDKLYEFAELLIQRGKAYVDSQSADEMRANRGSLTEGGKPSPFRDRTPA
ENLDLFRRMKAGEFKEGEHVLRAKIDMASPNMNMRDPVIYRIRYAHHYRTGDAWCVYPMYDYTHCISDALEGITHSLCTL
EFEDHRPLYDWVLNELAEAGVFTRPLPQQIEFSRLNLTYAITSKRKLLQLVTEGHVDGWDDPRMPTIVGVRRRGFTPESI
HLFCERIGVTKIDSWIDMSIFEGALRDDLDDKAARTVAVLDPLKLVIDNYPEDLEEACTAPVHPHHPDRGVRTFPISREL
WIEREDFVENPPKGYFRLFPGNKVRLRYGYVIECTGFDKDADGNVTAVHCNYFPDSKSGTEGANTYKVKGNIHWVSAKHA
QPAEVRIYDRLFKEPHPDAGGANFLEALNPDSKKIVQAYLEPGNGDVAPETRLQFERHGYFVADRVDSKPGKPVFNRIVG
LRDSWGKPA
>Mature_568_residues
STERNDAPAASNFIRNIIDDDNRTGKWGGRVETRFPPEPNGYLHIGHAKSICLNFSVARDYGGVCHLRFDDTNPEKESVE
YVDSIVDAVRWLGFDWRKDAVDHQYFASDYYDKLYEFAELLIQRGKAYVDSQSADEMRANRGSLTEGGKPSPFRDRTPAE
NLDLFRRMKAGEFKEGEHVLRAKIDMASPNMNMRDPVIYRIRYAHHYRTGDAWCVYPMYDYTHCISDALEGITHSLCTLE
FEDHRPLYDWVLNELAEAGVFTRPLPQQIEFSRLNLTYAITSKRKLLQLVTEGHVDGWDDPRMPTIVGVRRRGFTPESIH
LFCERIGVTKIDSWIDMSIFEGALRDDLDDKAARTVAVLDPLKLVIDNYPEDLEEACTAPVHPHHPDRGVRTFPISRELW
IEREDFVENPPKGYFRLFPGNKVRLRYGYVIECTGFDKDADGNVTAVHCNYFPDSKSGTEGANTYKVKGNIHWVSAKHAQ
PAEVRIYDRLFKEPHPDAGGANFLEALNPDSKKIVQAYLEPGNGDVAPETRLQFERHGYFVADRVDSKPGKPVFNRIVGL
RDSWGKPA

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=548, Percent_Identity=45.2554744525547, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI62241042, Length=528, Percent_Identity=34.8484848484849, Blast_Score=261, Evalue=9e-70,
Organism=Escherichia coli, GI1786895, Length=557, Percent_Identity=56.5529622980251, Blast_Score=628, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=122, Percent_Identity=30.327868852459, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17543332, Length=545, Percent_Identity=42.9357798165138, Blast_Score=396, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17511007, Length=529, Percent_Identity=30.6238185255198, Blast_Score=225, Evalue=6e-59,
Organism=Saccharomyces cerevisiae, GI6324742, Length=578, Percent_Identity=41.6955017301038, Blast_Score=417, Evalue=1e-117,
Organism=Saccharomyces cerevisiae, GI6321192, Length=530, Percent_Identity=33.3962264150943, Blast_Score=254, Evalue=2e-68,
Organism=Drosophila melanogaster, GI17864488, Length=551, Percent_Identity=41.923774954628, Blast_Score=407, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24649466, Length=419, Percent_Identity=36.5155131264916, Blast_Score=234, Evalue=1e-61,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 65074; Mature: 64942

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTERNDAPAASNFIRNIIDDDNRTGKWGGRVETRFPPEPNGYLHIGHAKSICLNFSVAR
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCEEEECCCCEEEEEEEEEC
DYGGVCHLRFDDTNPEKESVEYVDSIVDAVRWLGFDWRKDAVDHQYFASDYYDKLYEFAE
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHH
LLIQRGKAYVDSQSADEMRANRGSLTEGGKPSPFRDRTPAENLDLFRRMKAGEFKEGEHV
HHHHCCCHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEE
LRAKIDMASPNMNMRDPVIYRIRYAHHYRTGDAWCVYPMYDYTHCISDALEGITHSLCTL
EEEEEECCCCCCCCCCCEEEEEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEE
EFEDHRPLYDWVLNELAEAGVFTRPLPQQIEFSRLNLTYAITSKRKLLQLVTEGHVDGWD
EECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHCCCCCCC
DPRMPTIVGVRRRGFTPESIHLFCERIGVTKIDSWIDMSIFEGALRDDLDDKAARTVAVL
CCCCCCEEEHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHEEHHH
DPLKLVIDNYPEDLEEACTAPVHPHHPDRGVRTFPISRELWIEREDFVENPPKGYFRLFP
HHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCEECCCCHHHCCCCHHHHCCCCCCEEEECC
GNKVRLRYGYVIECTGFDKDADGNVTAVHCNYFPDSKSGTEGANTYKVKGNIHWVSAKHA
CCEEEEEEEEEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEECEEEEEECCCC
QPAEVRIYDRLFKEPHPDAGGANFLEALNPDSKKIVQAYLEPGNGDVAPETRLQFERHGY
CCCHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCE
FVADRVDSKPGKPVFNRIVGLRDSWGKPA
EEEECCCCCCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
STERNDAPAASNFIRNIIDDDNRTGKWGGRVETRFPPEPNGYLHIGHAKSICLNFSVAR
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCEEEECCCCEEEEEEEEEC
DYGGVCHLRFDDTNPEKESVEYVDSIVDAVRWLGFDWRKDAVDHQYFASDYYDKLYEFAE
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHH
LLIQRGKAYVDSQSADEMRANRGSLTEGGKPSPFRDRTPAENLDLFRRMKAGEFKEGEHV
HHHHCCCHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEE
LRAKIDMASPNMNMRDPVIYRIRYAHHYRTGDAWCVYPMYDYTHCISDALEGITHSLCTL
EEEEEECCCCCCCCCCCEEEEEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEE
EFEDHRPLYDWVLNELAEAGVFTRPLPQQIEFSRLNLTYAITSKRKLLQLVTEGHVDGWD
EECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHCCCCCCC
DPRMPTIVGVRRRGFTPESIHLFCERIGVTKIDSWIDMSIFEGALRDDLDDKAARTVAVL
CCCCCCEEEHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHEEHHH
DPLKLVIDNYPEDLEEACTAPVHPHHPDRGVRTFPISRELWIEREDFVENPPKGYFRLFP
HHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCEECCCCHHHCCCCHHHHCCCCCCEEEECC
GNKVRLRYGYVIECTGFDKDADGNVTAVHCNYFPDSKSGTEGANTYKVKGNIHWVSAKHA
CCEEEEEEEEEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEECEEEEEECCCC
QPAEVRIYDRLFKEPHPDAGGANFLEALNPDSKKIVQAYLEPGNGDVAPETRLQFERHGY
CCCHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCE
FVADRVDSKPGKPVFNRIVGLRDSWGKPA
EEEECCCCCCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA