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The map label for this gene is dinF [H]

Identifier: 116689336

GI number: 116689336

Start: 1445137

End: 1446516

Strand: Reverse

Name: dinF [H]

Synonym: Bcen2424_1314

Alternate gene names: 116689336

Gene position: 1446516-1445137 (Counterclockwise)

Preceding gene: 116689337

Following gene: 116689334

Centisome position: 41.52

GC content: 71.23

Gene sequence:

>1380_bases
ATGTCCGAATCCGCCTTACCGCTCGGGGCCGGCAGCGCGTCGGCCGCCGTCACGCATCGGCGCGTCCTCGCGCTCGCTTT
CCCGATCGTCCTTGCGAATCTGACCCAGCCGATCCTCGGCGCCGTCGACACGGCCGTCGCCGGCCACCTCGACGGGACGC
AATATCTCGGCGGTGTCGCGCTCGGCGGGCTGTTCTTCAATTTCGTGTTCTGGGGCTTCGGCTTCCTGCGGATGGGGACG
ACCGGCCTCGTCGCACAGGCGCATGGCGCCGGCGACGCCGCCGGAATCCGCCTGAACCTGCTGCGCGCGCTGATCGTCGC
GTTCGCGCTCGGCGCCGCGGTGCTGGCGCTGCAGGTGCCGCTGCTGTCGTTCGCGCTGTCCGCGCTCGGCGGCAGCGATG
CCGTCCGCGCGACGGCGCTCGCATACAGCCACGCACGGATCTGGAGCGCACCGTTCGCGCTCGCGAACTACGTGGTGCTC
GGCTACCTGCTGGGCGTGCAGCGCGTCCGGCTCGCACTCGTCGCGCAGGTGTTCATCAACGCGGTGAACATCGGCGCCGT
GCTGCTCTACGTGTACGGTTTCGGCTGGGGCATCGCCGGCATCGGCGCAGCGACCGCCACCGCGGACGCGTGCGGTTTCG
CGCTCGGCGCGTGGATGCTGTGGCGGCTGCGGCCGCGCGGCCTTGCACCGCTCGCGGTACGCGCGCTTGCCGACCGCGTC
GCGCTCAAGCGGCTGATCGCGCTCAATCGCGACATCTTCCTGCGCACGCTGTGCCTGCTCGGCGCGTTCGGCTGGTTCGC
GCATCTCGGCGCGAAACAAGGCGACGCGACGCTCGCCGCGAATGCGCTACTGCTGAATTTCCAGACCTTCATGGCGTACG
GCCTCGACGGCTTCGCGCATGCGGCCGAGGCGCTCGTCGGCGCGGCGGCCGGCGCGCGCGATCGCCGCGCCTTCCGGCAA
GCCGTGCGCGTCACGCTGTTCTGGTCGGCACTCGGCGCGCTGCTGTTCGCGCTCGTTTACTGGGCGGCGGGCGGCTGGAT
CGTTGCGCGCCTGACCGACCAGGCCGAGATCCGCGCCGTCGCGCTGCGCTACCTGCCGTGGGCCGCGATCTCGCCGATCG
TGTCGGTCTGGGGTTTCCTGCTCGACGGCGTGTTCATCGGCGCTACGCAGACGCAATCGCTGATGCGCGCGATGGTCGTG
TCGTTGTCGATCTTCGTCGCGGCCACGCTCGCCGCCGTCGGCATGTTCGGCAATCATGGCCTCTGGTTCGCGCTGCTGCT
GTTCATGGCGGCGCGCGGCGCGACGCTCGCACGCTACCTGCCGGCGCTGTTGCAGCGCGTTGGCGCCGAACCGCAGGCCG
CGCCTGCGGCCCGCGCGTGA

Upstream 100 bases:

>100_bases
GCCGAAACCGCCGCCGACTACGCGGCGCGCAATCCGGAGCTGTGGGCGGTCGTCGTCTCGCCGTGGGTCTGCGTGCAGGA
ACGCGCCTGACGCATCCGTC

Downstream 100 bases:

>100_bases
CTACGGGCCCGGCCGACCGTTACTGCTGCTGCACGGGTTTCGGCGGCGGCGCGTCGAGCATCGACGGCGGCGTCATGTCG
GTCGGCACGCCGTGATAGTC

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MSESALPLGAGSASAAVTHRRVLALAFPIVLANLTQPILGAVDTAVAGHLDGTQYLGGVALGGLFFNFVFWGFGFLRMGT
TGLVAQAHGAGDAAGIRLNLLRALIVAFALGAAVLALQVPLLSFALSALGGSDAVRATALAYSHARIWSAPFALANYVVL
GYLLGVQRVRLALVAQVFINAVNIGAVLLYVYGFGWGIAGIGAATATADACGFALGAWMLWRLRPRGLAPLAVRALADRV
ALKRLIALNRDIFLRTLCLLGAFGWFAHLGAKQGDATLAANALLLNFQTFMAYGLDGFAHAAEALVGAAAGARDRRAFRQ
AVRVTLFWSALGALLFALVYWAAGGWIVARLTDQAEIRAVALRYLPWAAISPIVSVWGFLLDGVFIGATQTQSLMRAMVV
SLSIFVAATLAAVGMFGNHGLWFALLLFMAARGATLARYLPALLQRVGAEPQAAPAARA

Sequences:

>Translated_459_residues
MSESALPLGAGSASAAVTHRRVLALAFPIVLANLTQPILGAVDTAVAGHLDGTQYLGGVALGGLFFNFVFWGFGFLRMGT
TGLVAQAHGAGDAAGIRLNLLRALIVAFALGAAVLALQVPLLSFALSALGGSDAVRATALAYSHARIWSAPFALANYVVL
GYLLGVQRVRLALVAQVFINAVNIGAVLLYVYGFGWGIAGIGAATATADACGFALGAWMLWRLRPRGLAPLAVRALADRV
ALKRLIALNRDIFLRTLCLLGAFGWFAHLGAKQGDATLAANALLLNFQTFMAYGLDGFAHAAEALVGAAAGARDRRAFRQ
AVRVTLFWSALGALLFALVYWAAGGWIVARLTDQAEIRAVALRYLPWAAISPIVSVWGFLLDGVFIGATQTQSLMRAMVV
SLSIFVAATLAAVGMFGNHGLWFALLLFMAARGATLARYLPALLQRVGAEPQAAPAARA
>Mature_458_residues
SESALPLGAGSASAAVTHRRVLALAFPIVLANLTQPILGAVDTAVAGHLDGTQYLGGVALGGLFFNFVFWGFGFLRMGTT
GLVAQAHGAGDAAGIRLNLLRALIVAFALGAAVLALQVPLLSFALSALGGSDAVRATALAYSHARIWSAPFALANYVVLG
YLLGVQRVRLALVAQVFINAVNIGAVLLYVYGFGWGIAGIGAATATADACGFALGAWMLWRLRPRGLAPLAVRALADRVA
LKRLIALNRDIFLRTLCLLGAFGWFAHLGAKQGDATLAANALLLNFQTFMAYGLDGFAHAAEALVGAAAGARDRRAFRQA
VRVTLFWSALGALLFALVYWAAGGWIVARLTDQAEIRAVALRYLPWAAISPIVSVWGFLLDGVFIGATQTQSLMRAMVVS
LSIFVAATLAAVGMFGNHGLWFALLLFMAARGATLARYLPALLQRVGAEPQAAPAARA

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=414, Percent_Identity=43.4782608695652, Blast_Score=243, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48014; Mature: 47883

Theoretical pI: Translated: 11.35; Mature: 11.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SESALPLGAGSASAAVTHRRVLALAFPIVLANLTQPILGAVDTAVAGHLDGTQYLGGVA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH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HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]