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The map label for this gene is hutI

Identifier: 116624289

GI number: 116624289

Start: 6533183

End: 6534439

Strand: Reverse

Name: hutI

Synonym: Acid_5207

Alternate gene names: 116624289

Gene position: 6534439-6533183 (Counterclockwise)

Preceding gene: 116624290

Following gene: 116624288

Centisome position: 65.57

GC content: 68.02

Gene sequence:

>1257_bases
ATGAGCGATTCCGCCCTCCTCAACTGTCGCCAGCTGGTCACCCTCGCCGGACCTCCGGGCCCGCGCACCGGACCCGCGAT
GCGCGAGCTCGCCATCATCCCCGATGGCGCCATGCGCATCCGCGACGGCTGCATCGCCGCCGTCGGCCCGCGCGCCGATA
TCGTGCGCTCTCTCGCCGGCGACACCGAAGTGATCGACGCCGGTTGGCGCGTCGTGCTCCCCGGCTTCATCGACGCTCAC
ACTCACCCTGTCTTCGCCGGCACCCGCGCCGCCGAGTATGAGCAGCGTGCCGAAGGCGCCACCTACGCCGAAATCGCCGC
GGCCGGCGGCGGCATTCGTTCCACCGTCCGCCGCACCCGCGAAGCCGGCGATCTCGAACTCGCCACCGCCGCGCGCCGGT
ACACCGATTGGTTCCTGCGCGGCGGCACCACCACCATCGAAGCCAAGTCCGGCTACGGACTCTCGCTCGACGACGAACTC
CGCATCCTGAAGACCATCCGCCTGCTTAACGCCGAGCGCCGCCTGCGCTACGTCCCCACCTTCCTCGGTGCTCATGAAAT
CCCCGACGAATACCGCGGTGAGATCGAGGATTATGTCGATCTCGTCATCCAGGAAATGCTGCCTGCCGTGGCGGAGGACA
ACCTCGCCGAGTACTGCGACGTCTTCTGCGAGCCCAACGTCTTCCCGCTCGATCCTGCCCGCGCGATCCTCCAAGCCGCC
CAATCGCTCGGCCTTCGCCTGCGCATCCACGCCGACCAGTTCACCGGTGATTACGCCGCCCTCCTCGCCGCCGAACTCGG
CGCCGCCACCGCCGATCACCTGGAATCCACTACCGCTCTTGGGCTCGCCGCGCTCCACGAAGCCGGCGTCCAGCCAGTAC
TCCTGCCCGCCTCGGTTTACAATCTCGGCTCCGCCCGCTATCCCGCTGCCCGCGACATGATCGCCCGCGGCATGGCCGTC
GTGCTCGCCACCGATTTCAACCCTGGCTCCTCGCCCACCGCCTCCATCCCGATGGTCCTCTCGCTGGCCTCTACGCAGAT
GAAGATGACCCCCGCTGAGTCCATCACGGCCGTGACGGTAAATGCCGCCCACAGCCTCGGCCGCGGCAGCCGGATCGGTT
CGCTCGAACCCGGCAAGGCGGCCGATTTCGCCATTCACGAGTGTGACGACTACCGCGAGCTCGCCTACTTCTTCGGCCGC
GAGCCCGCCAACGCCGTTTATCTCGCCGGCCAGTGCGTCTATCGACGGAGCGCGTGA

Upstream 100 bases:

>100_bases
CCGCCTTCCTCGGCGCCCTGGAAAATGTCAAAATCAATCTCGATTCCATTCAAGACGCAGCCTTCAAAGATCTCGTGATG
ACCCGCATGGCAGTTCTCAA

Downstream 100 bases:

>100_bases
TTTTCTACAACCGCGGGCGTCTTACGCACGTCCTTTATACTGGTACTTGATGCGGATTGGCCGGTTCTTCATCCTCGTGG
CGAGCTTCGTGCTGCTGGTT

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MSDSALLNCRQLVTLAGPPGPRTGPAMRELAIIPDGAMRIRDGCIAAVGPRADIVRSLAGDTEVIDAGWRVVLPGFIDAH
THPVFAGTRAAEYEQRAEGATYAEIAAAGGGIRSTVRRTREAGDLELATAARRYTDWFLRGGTTTIEAKSGYGLSLDDEL
RILKTIRLLNAERRLRYVPTFLGAHEIPDEYRGEIEDYVDLVIQEMLPAVAEDNLAEYCDVFCEPNVFPLDPARAILQAA
QSLGLRLRIHADQFTGDYAALLAAELGAATADHLESTTALGLAALHEAGVQPVLLPASVYNLGSARYPAARDMIARGMAV
VLATDFNPGSSPTASIPMVLSLASTQMKMTPAESITAVTVNAAHSLGRGSRIGSLEPGKAADFAIHECDDYRELAYFFGR
EPANAVYLAGQCVYRRSA

Sequences:

>Translated_418_residues
MSDSALLNCRQLVTLAGPPGPRTGPAMRELAIIPDGAMRIRDGCIAAVGPRADIVRSLAGDTEVIDAGWRVVLPGFIDAH
THPVFAGTRAAEYEQRAEGATYAEIAAAGGGIRSTVRRTREAGDLELATAARRYTDWFLRGGTTTIEAKSGYGLSLDDEL
RILKTIRLLNAERRLRYVPTFLGAHEIPDEYRGEIEDYVDLVIQEMLPAVAEDNLAEYCDVFCEPNVFPLDPARAILQAA
QSLGLRLRIHADQFTGDYAALLAAELGAATADHLESTTALGLAALHEAGVQPVLLPASVYNLGSARYPAARDMIARGMAV
VLATDFNPGSSPTASIPMVLSLASTQMKMTPAESITAVTVNAAHSLGRGSRIGSLEPGKAADFAIHECDDYRELAYFFGR
EPANAVYLAGQCVYRRSA
>Mature_417_residues
SDSALLNCRQLVTLAGPPGPRTGPAMRELAIIPDGAMRIRDGCIAAVGPRADIVRSLAGDTEVIDAGWRVVLPGFIDAHT
HPVFAGTRAAEYEQRAEGATYAEIAAAGGGIRSTVRRTREAGDLELATAARRYTDWFLRGGTTTIEAKSGYGLSLDDELR
ILKTIRLLNAERRLRYVPTFLGAHEIPDEYRGEIEDYVDLVIQEMLPAVAEDNLAEYCDVFCEPNVFPLDPARAILQAAQ
SLGLRLRIHADQFTGDYAALLAAELGAATADHLESTTALGLAALHEAGVQPVLLPASVYNLGSARYPAARDMIARGMAVV
LATDFNPGSSPTASIPMVLSLASTQMKMTPAESITAVTVNAAHSLGRGSRIGSLEPGKAADFAIHECDDYRELAYFFGRE
PANAVYLAGQCVYRRSA

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=429, Percent_Identity=38.9277389277389, Blast_Score=258, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI17555004, Length=422, Percent_Identity=31.2796208530806, Blast_Score=221, Evalue=4e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_SOLUE (Q01W05)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_826445.1
- ProteinModelPortal:   Q01W05
- SMR:   Q01W05
- STRING:   Q01W05
- GeneID:   4431852
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_5207
- NMPDR:   fig|234267.9.peg.4940
- eggNOG:   COG1228
- HOGENOM:   HBG686142
- OMA:   MNMACTL
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR006680
- InterPro:   IPR005920
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF01979 Amidohydro_1

EC number: =3.5.2.7

Molecular weight: Translated: 44759; Mature: 44628

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: BINDING 89-89 BINDING 102-102 BINDING 152-152 BINDING 185-185 BINDING 253-253

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSALLNCRQLVTLAGPPGPRTGPAMRELAIIPDGAMRIRDGCIAAVGPRADIVRSLAG
CCCCHHHHHHHHEEECCCCCCCCCCHHHEEEECCCCCCEECCCCEEECCCHHHHHHHHCC
DTEVIDAGWRVVLPGFIDAHTHPVFAGTRAAEYEQRAEGATYAEIAAAGGGIRSTVRRTR
CCEEECCCCEEEECCHHCCCCCCEECCCCHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHH
EAGDLELATAARRYTDWFLRGGTTTIEAKSGYGLSLDDELRILKTIRLLNAERRLRYVPT
CCCCCHHHHHHHHHHHHHEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FLGAHEIPDEYRGEIEDYVDLVIQEMLPAVAEDNLAEYCDVFCEPNVFPLDPARAILQAA
HHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHH
QSLGLRLRIHADQFTGDYAALLAAELGAATADHLESTTALGLAALHEAGVQPVLLPASVY
HHCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEECHHHH
NLGSARYPAARDMIARGMAVVLATDFNPGSSPTASIPMVLSLASTQMKMTPAESITAVTV
HCCCCCCCHHHHHHHCCEEEEEEECCCCCCCCCCCCHHHEEEHHHHEECCCCCCEEEEEE
NAAHSLGRGSRIGSLEPGKAADFAIHECDDYRELAYFFGREPANAVYLAGQCVYRRSA
ECHHHCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCCCEEEEECEEEEECCC
>Mature Secondary Structure 
SDSALLNCRQLVTLAGPPGPRTGPAMRELAIIPDGAMRIRDGCIAAVGPRADIVRSLAG
CCCHHHHHHHHEEECCCCCCCCCCHHHEEEECCCCCCEECCCCEEECCCHHHHHHHHCC
DTEVIDAGWRVVLPGFIDAHTHPVFAGTRAAEYEQRAEGATYAEIAAAGGGIRSTVRRTR
CCEEECCCCEEEECCHHCCCCCCEECCCCHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHH
EAGDLELATAARRYTDWFLRGGTTTIEAKSGYGLSLDDELRILKTIRLLNAERRLRYVPT
CCCCCHHHHHHHHHHHHHEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FLGAHEIPDEYRGEIEDYVDLVIQEMLPAVAEDNLAEYCDVFCEPNVFPLDPARAILQAA
HHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHH
QSLGLRLRIHADQFTGDYAALLAAELGAATADHLESTTALGLAALHEAGVQPVLLPASVY
HHCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEECHHHH
NLGSARYPAARDMIARGMAVVLATDFNPGSSPTASIPMVLSLASTQMKMTPAESITAVTV
HCCCCCCCHHHHHHHCCEEEEEEECCCCCCCCCCCCHHHEEEHHHHEECCCCCCEEEEEE
NAAHSLGRGSRIGSLEPGKAADFAIHECDDYRELAYFFGREPANAVYLAGQCVYRRSA
ECHHHCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCCCEEEEECEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA