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The map label for this gene is 116624290

Identifier: 116624290

GI number: 116624290

Start: 6534436

End: 6535845

Strand: Reverse

Name: 116624290

Synonym: Acid_5208

Alternate gene names: NA

Gene position: 6535845-6534436 (Counterclockwise)

Preceding gene: 116624291

Following gene: 116624289

Centisome position: 65.58

GC content: 65.53

Gene sequence:

>1410_bases
ATGCCGCGACAGCTCGTCGAATGTGTCCCCAATTTTTCCGAAGGCCGTGACCTCGCCAAAGTCGATGCCATCGTCCAGGC
CATCCTCGCCGTCCCCGAGGTCGCCCTCCTCGATCGCGAAATGGACGCCGATCACAACCGCAGCGTCCTCACCTTCGTCG
GTCCGCCGGCCGCCGTCGCCGACGCTGCCTTTCGCGCCGTCGAACGCGCCGTCGCGATCATCGATCTCACGCAGCACCAC
GGCGCTCATCCCCGCATCGGAGCCGCCGACGTCGTCCCCTTCATCCCCATCGAAGGCGTCACGCTCGAAGAGTGCGTCAA
GCTCGCCGAACGTCTCGGCGCCGAGATCTGGAGCAAGCTCAAGGTCCCCGTCTATCTCTACGAGTCCGCCGCCCGCCGCC
CCGATCGCACCAATCTGGAAAACATCCGCCGCGGCCAGTTCGAAGCCCTCCTCCAGGAAATGGGCACCGTCCCCGCGCGC
GATCCCGATATCGGCGACCCCGTCTGCCACCCCACCGCCGGCGCCATCGTCACCGGCGCGCGCAAATTCCTGATCGCCTA
CAACGTCAACCTCAACACGCCCGATCTCTCCATCGCGAAGAAGATCGCCAAGACCATCCGCTTCTCCAACGGCGGCTTCC
GCTACGTCAAGTCGATGGGCGTCATGCTCGCCTCCCGCAACCTCGCGCAGGTCTCCATCAACCTCACCGATTTCGAGCAG
ACCCCCATGCACCTCGTGTTCGAGACCGTGCGCCGCGAAGCCGAGCGCTACGGCGTCTCCGTAATCGGTAGCGAGATCGT
CGGCCTCATTCCCAAGAAGGCCATCGAGCTCTCCGCCGAATACTTCCTCCGCTACGAAAACTTCCGCCCCGAGCTCGTGC
TCGAGAACCGGATCGCCGAGGCCCTCGCCACCCGCTCCGGCCTTTCCGAATTCCTCGACGCGCTCGCTTCTCCCGCCGCC
ACTCCCGGCGGAGGCAGCGCCGCCGCCGCCGCCGCCGCGATGGCCGCCGCGCTCGGCTCCATGGTCACCCGCCTCGCCAA
GCTCGACGCGTCCTCCTTCGAAGACGACCGCCGCTTTTTCACCGAGGCCGCCGACCGCGACGCCGAAGCCTTCAACCTCG
TCATGGCCGCCTATAAACGACCCAAGGCCGAACGCGCGCCCTTCGTCGAGGATGCCCTCCACGGCGCCGCCGAAGTTCCG
CTCCAGGTGATGGAGCGCGCCCACGCCCTGCAGTCCCGACTACACGCGCTCGAAGTTCCCGCCAAATTCGGCAGCGATCT
CGCCGTCGCCAAGTCGCTCGTCGTGGCCGCCTTCCTCGGCGCCCTGGAAAATGTCAAAATCAATCTCGATTCCATTCAAG
ACGCAGCCTTCAAAGATCTCGTGATGACCCGCATGGCAGTTCTCAAATGA

Upstream 100 bases:

>100_bases
TCGATACACGCATCGTCATCGCCATGCGAACCGCGACCGTCTCTCGCCAACTGGCGAGCAAGGGAGCGATCTAAGATTCC
ACGCTACATTAGGAGAGTAA

Downstream 100 bases:

>100_bases
GCGATTCCGCCCTCCTCAACTGTCGCCAGCTGGTCACCCTCGCCGGACCTCCGGGCCCGCGCACCGGACCCGCGATGCGC
GAGCTCGCCATCATCCCCGA

Product: glutamate formiminotransferase

Products: tetrahydrofolate; N-formimidoyl-L-glutamate

Alternate protein names: Formimidoyltransferase-Cyclodeaminase; Glutamate Formimidoyltransferase; Formiminotransferase-Cyclodeaminase; Formiminotransferase Domain Protein; Formiminotransferase-Cyclodeaminase-Related Protein; Formiminotransferase-Like; Formiminotransferase

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MPRQLVECVPNFSEGRDLAKVDAIVQAILAVPEVALLDREMDADHNRSVLTFVGPPAAVADAAFRAVERAVAIIDLTQHH
GAHPRIGAADVVPFIPIEGVTLEECVKLAERLGAEIWSKLKVPVYLYESAARRPDRTNLENIRRGQFEALLQEMGTVPAR
DPDIGDPVCHPTAGAIVTGARKFLIAYNVNLNTPDLSIAKKIAKTIRFSNGGFRYVKSMGVMLASRNLAQVSINLTDFEQ
TPMHLVFETVRREAERYGVSVIGSEIVGLIPKKAIELSAEYFLRYENFRPELVLENRIAEALATRSGLSEFLDALASPAA
TPGGGSAAAAAAAMAAALGSMVTRLAKLDASSFEDDRRFFTEAADRDAEAFNLVMAAYKRPKAERAPFVEDALHGAAEVP
LQVMERAHALQSRLHALEVPAKFGSDLAVAKSLVVAAFLGALENVKINLDSIQDAAFKDLVMTRMAVLK

Sequences:

>Translated_469_residues
MPRQLVECVPNFSEGRDLAKVDAIVQAILAVPEVALLDREMDADHNRSVLTFVGPPAAVADAAFRAVERAVAIIDLTQHH
GAHPRIGAADVVPFIPIEGVTLEECVKLAERLGAEIWSKLKVPVYLYESAARRPDRTNLENIRRGQFEALLQEMGTVPAR
DPDIGDPVCHPTAGAIVTGARKFLIAYNVNLNTPDLSIAKKIAKTIRFSNGGFRYVKSMGVMLASRNLAQVSINLTDFEQ
TPMHLVFETVRREAERYGVSVIGSEIVGLIPKKAIELSAEYFLRYENFRPELVLENRIAEALATRSGLSEFLDALASPAA
TPGGGSAAAAAAAMAAALGSMVTRLAKLDASSFEDDRRFFTEAADRDAEAFNLVMAAYKRPKAERAPFVEDALHGAAEVP
LQVMERAHALQSRLHALEVPAKFGSDLAVAKSLVVAAFLGALENVKINLDSIQDAAFKDLVMTRMAVLK
>Mature_468_residues
PRQLVECVPNFSEGRDLAKVDAIVQAILAVPEVALLDREMDADHNRSVLTFVGPPAAVADAAFRAVERAVAIIDLTQHHG
AHPRIGAADVVPFIPIEGVTLEECVKLAERLGAEIWSKLKVPVYLYESAARRPDRTNLENIRRGQFEALLQEMGTVPARD
PDIGDPVCHPTAGAIVTGARKFLIAYNVNLNTPDLSIAKKIAKTIRFSNGGFRYVKSMGVMLASRNLAQVSINLTDFEQT
PMHLVFETVRREAERYGVSVIGSEIVGLIPKKAIELSAEYFLRYENFRPELVLENRIAEALATRSGLSEFLDALASPAAT
PGGGSAAAAAAAMAAALGSMVTRLAKLDASSFEDDRRFFTEAADRDAEAFNLVMAAYKRPKAERAPFVEDALHGAAEVPL
QVMERAHALQSRLHALEVPAKFGSDLAVAKSLVVAAFLGALENVKINLDSIQDAAFKDLVMTRMAVLK

Specific function: Unknown

COG id: COG3643

COG function: function code E; Glutamate formiminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI46255035, Length=525, Percent_Identity=36, Blast_Score=266, Evalue=3e-71,
Organism=Homo sapiens, GI11140815, Length=525, Percent_Identity=36, Blast_Score=266, Evalue=3e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.2.5

Molecular weight: Translated: 50819; Mature: 50688

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRQLVECVPNFSEGRDLAKVDAIVQAILAVPEVALLDREMDADHNRSVLTFVGPPAAVA
CCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCEEEEECCCHHHH
DAAFRAVERAVAIIDLTQHHGAHPRIGAADVVPFIPIEGVTLEECVKLAERLGAEIWSKL
HHHHHHHHHHHHHHEEHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
KVPVYLYESAARRPDRTNLENIRRGQFEALLQEMGTVPARDPDIGDPVCHPTAGAIVTGA
CCCEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCC
RKFLIAYNVNLNTPDLSIAKKIAKTIRFSNGGFRYVKSMGVMLASRNLAQVSINLTDFEQ
EEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCC
TPMHLVFETVRREAERYGVSVIGSEIVGLIPKKAIELSAEYFLRYENFRPELVLENRIAE
CHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ALATRSGLSEFLDALASPAATPGGGSAAAAAAAMAAALGSMVTRLAKLDASSFEDDRRFF
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
TEAADRDAEAFNLVMAAYKRPKAERAPFVEDALHGAAEVPLQVMERAHALQSRLHALEVP
HHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHCC
AKFGSDLAVAKSLVVAAFLGALENVKINLDSIQDAAFKDLVMTRMAVLK
HHHCCHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PRQLVECVPNFSEGRDLAKVDAIVQAILAVPEVALLDREMDADHNRSVLTFVGPPAAVA
CHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCEEEEECCCHHHH
DAAFRAVERAVAIIDLTQHHGAHPRIGAADVVPFIPIEGVTLEECVKLAERLGAEIWSKL
HHHHHHHHHHHHHHEEHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
KVPVYLYESAARRPDRTNLENIRRGQFEALLQEMGTVPARDPDIGDPVCHPTAGAIVTGA
CCCEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCC
RKFLIAYNVNLNTPDLSIAKKIAKTIRFSNGGFRYVKSMGVMLASRNLAQVSINLTDFEQ
EEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCC
TPMHLVFETVRREAERYGVSVIGSEIVGLIPKKAIELSAEYFLRYENFRPELVLENRIAE
CHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ALATRSGLSEFLDALASPAATPGGGSAAAAAAAMAAALGSMVTRLAKLDASSFEDDRRFF
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
TEAADRDAEAFNLVMAAYKRPKAERAPFVEDALHGAAEVPLQVMERAHALQSRLHALEVP
HHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHCC
AKFGSDLAVAKSLVVAAFLGALENVKINLDSIQDAAFKDLVMTRMAVLK
HHHCCHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-formimidoyltetrahydrofolate; L-glutamate

Specific reaction: 5-formimidoyltetrahydrofolate + L-glutamate = tetrahydrofolate + N-formimidoyl-L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA