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The map label for this gene is atoS [C]

Identifier: 116624255

GI number: 116624255

Start: 6496752

End: 6498269

Strand: Reverse

Name: atoS [C]

Synonym: Acid_5173

Alternate gene names: 116624255

Gene position: 6498269-6496752 (Counterclockwise)

Preceding gene: 116624256

Following gene: 116624249

Centisome position: 65.21

GC content: 59.95

Gene sequence:

>1518_bases
ATGCCGGTAAAGAGACCGTCGAAAGATCGCGAGAGCAAGCTCTGGCTTTTGTTTGACGAGCATCCGAACCCGATGTTAAT
CGTCGATCCCGAAAACGGGAAGATTCTGGAAGCCAATGCCGCGGCAGTCGCGCTATACGGCTATTCACCTGAGGAATTTC
GTAACATCGCCTGGGAGTCCCTTCGGGTCCACGACGACTTACCGCGTGGATTAACTACAGACTCCGTCCGTCACCGAACT
CGCGGCGGCGGGGTCATCGAGGTGGAGCCTTCTACGCGTCAGATTGAGTTTGGCGGGGAGCCGGCACAGTTGACGGTGTT
GAACGACGTCACGATCCGCCGGCATCTCGAGGAGCAATTGCGCCAGGCGCAAAAGATGGAAGCCGTCGGCATGCTGGCGG
GCGGTGTGGCGCATGATTTCAACAATCTGCTGACCATCATTACCGGGTATAGCCAACTGATCCTCAACAGCCTCCACAGC
GAGGATCCGAACCATCATTCGGCGGAGCAGATCATGAAGGCGGGGGAGCGGGCGGCCGCACTTACCAGTCAGTTATTGGC
CTTCAGCCGGCGCCAGGCGTTGCAACCGAGAGTGCTGGACCTGAATAAGCTGGTCACGGCGATGAGCACGATGTTGCGCC
GGTTGATTGGCGAGGATATCGACATCCAGTTCGTGCTCCGTCCCGATCTCGGGATGGTGAGCGCCGACCCCGGCCAAATG
GAGCAGGTGCTGATGAACCTGGTGGTGAACGCACGCGACGCCATGCCCAACGGCGGGACGTTGACGATTGAAACCGCCAA
TGTGCAAATCGATGAAGGCTATTCGCAGCGTCACCTTCCGGTGAAGCAGGGTCCTTACACGATGATCGCGGTGAGCGACA
ACGGCACCGGCATGGACGAGTTGGCGCAGCAGCGTCTTTTCGAACCGTTCTTCACCACGAAGGGCACCGGCCGCGGCACC
GGGCTGGGGCTTTCGAGCGTGTTGGGCATTATCAAGCAGACCGGCGGCACGATCAACGTCTACAGCGTTCCCAACAGCGG
CACGTCGATGAAAGTGTACCTGCCGCGGGTGGACCGGCCCGCGGTGATCGAATCCGAAGTTCCGCAGCAGACGGTTTCCC
GAGGCTCGGAGACGGTTCTGGTGGTGGAAGACGATGAGATGGTCCGCAACCTGGTGCGCGAGACGTTGAACCGTTCGGGC
TACCGGGTGCTGGATGCGGATGGTCCGCTGGAAGCACGGCGCATCGCGGATGCTTATCGGGGGCGAATCCACCTGCTGAT
TACCGACGTGGTGATGCCTAAGGTCAGCGGCCGCGAACTAGCGGCGCAACTCACGGAGCGCCGGCGCGACATGAAGGTGC
TCTACATGTCTGGCTATACGGATAGCGCGATCGTGAATACGGGTATTCTGCAGAAGGAAGTCGCGTTCGTGCAAAAGCCT
TTCACGCCAGCAGCCTTCACGCAAAAAGTCCGCGAGGTGCTGGAAAGCGGTAGCCGTACACGCGGGGCAGCGGAATAA

Upstream 100 bases:

>100_bases
CCACCGGGATATTCCGATTGAGTCGCGCTGTCATTCTTTCGTATTCTTGTCGGTAGGGTAATAGGGCTACCTGGACAAGG
CAGCGAGATCGGATTCCACG

Downstream 100 bases:

>100_bases
GACTCAAAGGATCAGGGACCGAGCCTAGATAGCCAGCAGTTGGGCGCCCGCGATGCCGGCGAAGAGGGCGGCGAAGCCGA
GGAAGGTGCCGAACGGGAGT

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MPVKRPSKDRESKLWLLFDEHPNPMLIVDPENGKILEANAAAVALYGYSPEEFRNIAWESLRVHDDLPRGLTTDSVRHRT
RGGGVIEVEPSTRQIEFGGEPAQLTVLNDVTIRRHLEEQLRQAQKMEAVGMLAGGVAHDFNNLLTIITGYSQLILNSLHS
EDPNHHSAEQIMKAGERAAALTSQLLAFSRRQALQPRVLDLNKLVTAMSTMLRRLIGEDIDIQFVLRPDLGMVSADPGQM
EQVLMNLVVNARDAMPNGGTLTIETANVQIDEGYSQRHLPVKQGPYTMIAVSDNGTGMDELAQQRLFEPFFTTKGTGRGT
GLGLSSVLGIIKQTGGTINVYSVPNSGTSMKVYLPRVDRPAVIESEVPQQTVSRGSETVLVVEDDEMVRNLVRETLNRSG
YRVLDADGPLEARRIADAYRGRIHLLITDVVMPKVSGRELAAQLTERRRDMKVLYMSGYTDSAIVNTGILQKEVAFVQKP
FTPAAFTQKVREVLESGSRTRGAAE

Sequences:

>Translated_505_residues
MPVKRPSKDRESKLWLLFDEHPNPMLIVDPENGKILEANAAAVALYGYSPEEFRNIAWESLRVHDDLPRGLTTDSVRHRT
RGGGVIEVEPSTRQIEFGGEPAQLTVLNDVTIRRHLEEQLRQAQKMEAVGMLAGGVAHDFNNLLTIITGYSQLILNSLHS
EDPNHHSAEQIMKAGERAAALTSQLLAFSRRQALQPRVLDLNKLVTAMSTMLRRLIGEDIDIQFVLRPDLGMVSADPGQM
EQVLMNLVVNARDAMPNGGTLTIETANVQIDEGYSQRHLPVKQGPYTMIAVSDNGTGMDELAQQRLFEPFFTTKGTGRGT
GLGLSSVLGIIKQTGGTINVYSVPNSGTSMKVYLPRVDRPAVIESEVPQQTVSRGSETVLVVEDDEMVRNLVRETLNRSG
YRVLDADGPLEARRIADAYRGRIHLLITDVVMPKVSGRELAAQLTERRRDMKVLYMSGYTDSAIVNTGILQKEVAFVQKP
FTPAAFTQKVREVLESGSRTRGAAE
>Mature_504_residues
PVKRPSKDRESKLWLLFDEHPNPMLIVDPENGKILEANAAAVALYGYSPEEFRNIAWESLRVHDDLPRGLTTDSVRHRTR
GGGVIEVEPSTRQIEFGGEPAQLTVLNDVTIRRHLEEQLRQAQKMEAVGMLAGGVAHDFNNLLTIITGYSQLILNSLHSE
DPNHHSAEQIMKAGERAAALTSQLLAFSRRQALQPRVLDLNKLVTAMSTMLRRLIGEDIDIQFVLRPDLGMVSADPGQME
QVLMNLVVNARDAMPNGGTLTIETANVQIDEGYSQRHLPVKQGPYTMIAVSDNGTGMDELAQQRLFEPFFTTKGTGRGTG
LGLSSVLGIIKQTGGTINVYSVPNSGTSMKVYLPRVDRPAVIESEVPQQTVSRGSETVLVVEDDEMVRNLVRETLNRSGY
RVLDADGPLEARRIADAYRGRIHLLITDVVMPKVSGRELAAQLTERRRDMKVLYMSGYTDSAIVNTGILQKEVAFVQKPF
TPAAFTQKVREVLESGSRTRGAAE

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=357, Percent_Identity=29.9719887955182, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1790436, Length=244, Percent_Identity=29.5081967213115, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1790300, Length=246, Percent_Identity=31.7073170731707, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788713, Length=354, Percent_Identity=25.7062146892655, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1786912, Length=256, Percent_Identity=27.34375, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI145693157, Length=335, Percent_Identity=24.7761194029851, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081816, Length=348, Percent_Identity=22.7011494252874, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55816; Mature: 55684

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVKRPSKDRESKLWLLFDEHPNPMLIVDPENGKILEANAAAVALYGYSPEEFRNIAWES
CCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCEEECCCCEEEEECCCHHHHHHHHHHH
LRVHDDLPRGLTTDSVRHRTRGGGVIEVEPSTRQIEFGGEPAQLTVLNDVTIRRHLEEQL
HEECCCCCCCCCCHHHHHHCCCCCEEEECCCCEEEEECCCCEEEEEECHHHHHHHHHHHH
RQAQKMEAVGMLAGGVAHDFNNLLTIITGYSQLILNSLHSEDPNHHSAEQIMKAGERAAA
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHH
LTSQLLAFSRRQALQPRVLDLNKLVTAMSTMLRRLIGEDIDIQFVLRPDLGMVSADPGQM
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHH
EQVLMNLVVNARDAMPNGGTLTIETANVQIDEGYSQRHLPVKQGPYTMIAVSDNGTGMDE
HHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCHHH
LAQQRLFEPFFTTKGTGRGTGLGLSSVLGIIKQTGGTINVYSVPNSGTSMKVYLPRVDRP
HHHHHHCCHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCC
AVIESEVPQQTVSRGSETVLVVEDDEMVRNLVRETLNRSGYRVLDADGPLEARRIADAYR
CCCCCCCCHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHC
GRIHLLITDVVMPKVSGRELAAQLTERRRDMKVLYMSGYTDSAIVNTGILQKEVAFVQKP
CEEEEEEEEHHCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHCCHHHHHHHHHHCC
FTPAAFTQKVREVLESGSRTRGAAE
CCHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PVKRPSKDRESKLWLLFDEHPNPMLIVDPENGKILEANAAAVALYGYSPEEFRNIAWES
CCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCEEECCCCEEEEECCCHHHHHHHHHHH
LRVHDDLPRGLTTDSVRHRTRGGGVIEVEPSTRQIEFGGEPAQLTVLNDVTIRRHLEEQL
HEECCCCCCCCCCHHHHHHCCCCCEEEECCCCEEEEECCCCEEEEEECHHHHHHHHHHHH
RQAQKMEAVGMLAGGVAHDFNNLLTIITGYSQLILNSLHSEDPNHHSAEQIMKAGERAAA
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHH
LTSQLLAFSRRQALQPRVLDLNKLVTAMSTMLRRLIGEDIDIQFVLRPDLGMVSADPGQM
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHH
EQVLMNLVVNARDAMPNGGTLTIETANVQIDEGYSQRHLPVKQGPYTMIAVSDNGTGMDE
HHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCHHH
LAQQRLFEPFFTTKGTGRGTGLGLSSVLGIIKQTGGTINVYSVPNSGTSMKVYLPRVDRP
HHHHHHCCHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCC
AVIESEVPQQTVSRGSETVLVVEDDEMVRNLVRETLNRSGYRVLDADGPLEARRIADAYR
CCCCCCCCHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHC
GRIHLLITDVVMPKVSGRELAAQLTERRRDMKVLYMSGYTDSAIVNTGILQKEVAFVQKP
CEEEEEEEEHHCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHCCHHHHHHHHHHCC
FTPAAFTQKVREVLESGSRTRGAAE
CCHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA