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The map label for this gene is iolG [H]

Identifier: 116622967

GI number: 116622967

Start: 4903709

End: 4905013

Strand: Reverse

Name: iolG [H]

Synonym: Acid_3870

Alternate gene names: 116622967

Gene position: 4905013-4903709 (Counterclockwise)

Preceding gene: 116622968

Following gene: 116622966

Centisome position: 49.22

GC content: 60.69

Gene sequence:

>1305_bases
ATGAATAATACCCGCAGAGAGTTGCTGACCGCCGCCGGTGCCGCCTTCACCACCTCGCTCTTCACCGGGCGCGTCAAAGG
CGCCAATGACCGCATTGCGGTGGGCTTCATCGGCCTGGGTGCCATGGGCTCGGGCAATCTCGGCTATGCCATGAAAGTCC
CGGAGGCGCAGCCCGTTGCCCTCTGCGACGTCTACCAGCCGCACCTCGAACGCGCTGAAGCGGCCGCCAAGAAGGGCGGC
TTCGACGTGAAATCCGTCAAGGACTTCCGCGATATTCTCGCCGACAAATCGATCGACGCCGTCTGCATTTCCACGCCCGA
CCACTGGCATGCCTACATGGAAGTGGAAGCCTGCAAAGCGGGCAAGGACGTGTATGTGGAGAAGCCCGCCTGCGTCTACG
TGGAAGAGGGCGTAAAGATGGTACAGGCTGCGCGCAAATACAAGCGGGTCGTGCAGGCCGGAACCATGCAGCGCTCCGGC
GGCTACTTCAAGAAGGCGGCCGAAATTGTGCAAAGCGGCGCGCTCGGCGACGTCACCTTCTGCCATGCCTTCCAATCCGG
TCTCACCAAACAGGAAGGCTACGGCAACCCGCCAGATAGCGAACCGCCGCTCGGACTCGATTGGGATATGTGGCTCGGAC
CCGCCCCCAAGGTGCCCTTCAACGCCAACCGCTGGGGCGTGAAGGCCGCGACCTTCCCCACCTTCCGCTACTTCTGGGAT
TACGCGGGCGGCGCGATGACGGATTGGGGAGTCCACCTGATCGACCCCATCCACCAGTGTTTCGGCGAGCCGATGCCTCT
CTCCGTCGCCGCCATGGGCAACAAGTTCTACGTGCAGGACAACGTCCAGACTCCCGACACGATGGAGGCCGTGTATCAAT
ATCCGAAGTTCCTCCAGACGTACGAGAGCCGCACCGCCAATCCGCTACAGATGTTCAACTCCGGCAACGGCACCGCGATC
CATGGTACGGAGGGCAGCATCCTGGTGAACCGCAGCGGCTGCACCGTCATCCCCGCGGGCAAGTCAAGTAAGCTGGAAGC
CGTTAGCTATGAGAAGGATAACGAGATGAGCCAGATGAACGTTCCGCACTGGAAGAACTTCATAGCCTGCATCAAGAGCC
GCGAGAAGCCGACCAGCGACATTGAAACCTGCGTGCGATCTTCCACCGCCTGCATCCTGGCAAATCTCTCTATGCGCCAC
GGTCTCCGGCTCGATTGGGATGAAAAGGCCTGGACCGTGAAGCAGGAATCGGTACGACAGTACTTGAAGGCCCGTTATCG
CGCTCCGTGGAAACTCGAAGTATAA

Upstream 100 bases:

>100_bases
TATATGAAGCAGGCCCTCGCGTAGAGATTAGCGGGGCGGGCGCTTCCGCCTGCCCCTACCCTTGCGCCCGTAGTTTCAAT
GGTGATACCAACAAGGAATC

Downstream 100 bases:

>100_bases
GAATTCACACCGGCTTGCGCCAACTTCCGCTTTGGGATTGCGAACGGCGGATATCGGGTTGTAAATTGAAGTTCTAACCG
AACCCCTCGTTTATGTCCGT

Product: oxidoreductase domain-containing protein

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase; MI 2-dehydrogenase [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MNNTRRELLTAAGAAFTTSLFTGRVKGANDRIAVGFIGLGAMGSGNLGYAMKVPEAQPVALCDVYQPHLERAEAAAKKGG
FDVKSVKDFRDILADKSIDAVCISTPDHWHAYMEVEACKAGKDVYVEKPACVYVEEGVKMVQAARKYKRVVQAGTMQRSG
GYFKKAAEIVQSGALGDVTFCHAFQSGLTKQEGYGNPPDSEPPLGLDWDMWLGPAPKVPFNANRWGVKAATFPTFRYFWD
YAGGAMTDWGVHLIDPIHQCFGEPMPLSVAAMGNKFYVQDNVQTPDTMEAVYQYPKFLQTYESRTANPLQMFNSGNGTAI
HGTEGSILVNRSGCTVIPAGKSSKLEAVSYEKDNEMSQMNVPHWKNFIACIKSREKPTSDIETCVRSSTACILANLSMRH
GLRLDWDEKAWTVKQESVRQYLKARYRAPWKLEV

Sequences:

>Translated_434_residues
MNNTRRELLTAAGAAFTTSLFTGRVKGANDRIAVGFIGLGAMGSGNLGYAMKVPEAQPVALCDVYQPHLERAEAAAKKGG
FDVKSVKDFRDILADKSIDAVCISTPDHWHAYMEVEACKAGKDVYVEKPACVYVEEGVKMVQAARKYKRVVQAGTMQRSG
GYFKKAAEIVQSGALGDVTFCHAFQSGLTKQEGYGNPPDSEPPLGLDWDMWLGPAPKVPFNANRWGVKAATFPTFRYFWD
YAGGAMTDWGVHLIDPIHQCFGEPMPLSVAAMGNKFYVQDNVQTPDTMEAVYQYPKFLQTYESRTANPLQMFNSGNGTAI
HGTEGSILVNRSGCTVIPAGKSSKLEAVSYEKDNEMSQMNVPHWKNFIACIKSREKPTSDIETCVRSSTACILANLSMRH
GLRLDWDEKAWTVKQESVRQYLKARYRAPWKLEV
>Mature_434_residues
MNNTRRELLTAAGAAFTTSLFTGRVKGANDRIAVGFIGLGAMGSGNLGYAMKVPEAQPVALCDVYQPHLERAEAAAKKGG
FDVKSVKDFRDILADKSIDAVCISTPDHWHAYMEVEACKAGKDVYVEKPACVYVEEGVKMVQAARKYKRVVQAGTMQRSG
GYFKKAAEIVQSGALGDVTFCHAFQSGLTKQEGYGNPPDSEPPLGLDWDMWLGPAPKVPFNANRWGVKAATFPTFRYFWD
YAGGAMTDWGVHLIDPIHQCFGEPMPLSVAAMGNKFYVQDNVQTPDTMEAVYQYPKFLQTYESRTANPLQMFNSGNGTAI
HGTEGSILVNRSGCTVIPAGKSSKLEAVSYEKDNEMSQMNVPHWKNFIACIKSREKPTSDIETCVRSSTACILANLSMRH
GLRLDWDEKAWTVKQESVRQYLKARYRAPWKLEV

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) [H]

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.18 [H]

Molecular weight: Translated: 47977; Mature: 47977

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNTRRELLTAAGAAFTTSLFTGRVKGANDRIAVGFIGLGAMGSGNLGYAMKVPEAQPVA
CCCHHHHHHHHHCHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCEEEECCCCCCEE
LCDVYQPHLERAEAAAKKGGFDVKSVKDFRDILADKSIDAVCISTPDHWHAYMEVEACKA
EHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEEEEHHCC
GKDVYVEKPACVYVEEGVKMVQAARKYKRVVQAGTMQRSGGYFKKAAEIVQSGALGDVTF
CCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHH
CHAFQSGLTKQEGYGNPPDSEPPLGLDWDMWLGPAPKVPFNANRWGVKAATFPTFRYFWD
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHH
YAGGAMTDWGVHLIDPIHQCFGEPMPLSVAAMGNKFYVQDNVQTPDTMEAVYQYPKFLQT
HCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHH
YESRTANPLQMFNSGNGTAIHGTEGSILVNRSGCTVIPAGKSSKLEAVSYEKDNEMSQMN
HHHCCCCHHHHHCCCCCCEEECCCCCEEEECCCCEEEECCCCCCEEEECCCCCCCHHHCC
VPHWKNFIACIKSREKPTSDIETCVRSSTACILANLSMRHGLRLDWDEKAWTVKQESVRQ
CCHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEECHHHCCCCCCCCCCHHEECHHHHHH
YLKARYRAPWKLEV
HHHHHCCCCEEECC
>Mature Secondary Structure
MNNTRRELLTAAGAAFTTSLFTGRVKGANDRIAVGFIGLGAMGSGNLGYAMKVPEAQPVA
CCCHHHHHHHHHCHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCEEEECCCCCCEE
LCDVYQPHLERAEAAAKKGGFDVKSVKDFRDILADKSIDAVCISTPDHWHAYMEVEACKA
EHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEEEEHHCC
GKDVYVEKPACVYVEEGVKMVQAARKYKRVVQAGTMQRSGGYFKKAAEIVQSGALGDVTF
CCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHH
CHAFQSGLTKQEGYGNPPDSEPPLGLDWDMWLGPAPKVPFNANRWGVKAATFPTFRYFWD
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHH
YAGGAMTDWGVHLIDPIHQCFGEPMPLSVAAMGNKFYVQDNVQTPDTMEAVYQYPKFLQT
HCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHH
YESRTANPLQMFNSGNGTAIHGTEGSILVNRSGCTVIPAGKSSKLEAVSYEKDNEMSQMN
HHHCCCCHHHHHCCCCCCEEECCCCCEEEECCCCEEEECCCCCCEEEECCCCCCCHHHCC
VPHWKNFIACIKSREKPTSDIETCVRSSTACILANLSMRHGLRLDWDEKAWTVKQESVRQ
CCHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEECHHHCCCCCCCCCCHHEECHHHHHH
YLKARYRAPWKLEV
HHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA