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The map label for this gene is efp [H]

Identifier: 116622320

GI number: 116622320

Start: 4067937

End: 4068512

Strand: Reverse

Name: efp [H]

Synonym: Acid_3214

Alternate gene names: 116622320

Gene position: 4068512-4067937 (Counterclockwise)

Preceding gene: 116622321

Following gene: 116622312

Centisome position: 40.83

GC content: 59.38

Gene sequence:

>576_bases
ATGGCCGTTTTAATCGATGCGATTGACGTTAAGAAGAGGACTCTGTTCGAGTTGGACAACGTTCCGTTTTCCTGTTTGGA
GGCGGAGGTGAACACGCCAACCGCGCGCGGCGGCCAGACACTGGTGCGGCTGAAGGTTCGCAACCTGCTGACCAACGCGG
TGTTCGAGAAGACGTTCAAGGCGGGCGAGAAATTCAAGGAGCCGGACCTGCAGCTGGTGTCGGCATCGTATTTATACAGC
GACGGCAGCGGGTCGCATTTCCTTGACCAGGAGAGCTTCGAGACGCACACGCTTTCCGGGGAGATCATGGGCAACGCGCT
GGACTTCCTGATCGACGGCACGCTGGTGGAACTGCTGAAATTCAACGGCAATCCGATCGGCTTGAACCTGCCGGCGTCTG
TGGAGCTGACGGTCACGTTCACCGAGCCCGGCGTGCGCGGGGATTCCTCGAGCGGCAGCGTGACCAAGCCCGCGAAGCTG
GAGACGGGACTGGAAATCCGGGTGCCTCTGTTTATTAAGGAAGGCGAGAAGGTGAAGGTGTCCACGGAGAACCGGAGCTT
CTCGGGGAGAGCGTAA

Upstream 100 bases:

>100_bases
GCATACGGATCGCGCGGTGAAGCAGCAGACGCTGCCGGAGGCGTTGGAATACGTGTGGCAGGGGTATCCGATCGCGGCGC
CGAAGAATTAAACTGGGGTA

Downstream 100 bases:

>100_bases
GGGCACTTTGCACTAAACGGCTATTTAAGCTGATTTCCGAATGGAATCATGCCGCCGGTCAGCACGGTCTTTGGAAATTC
ACCGGAGCCGCAGATGATGA

Product: translation elongation factor P

Products: NA

Alternate protein names: EF-P [H]

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MAVLIDAIDVKKRTLFELDNVPFSCLEAEVNTPTARGGQTLVRLKVRNLLTNAVFEKTFKAGEKFKEPDLQLVSASYLYS
DGSGSHFLDQESFETHTLSGEIMGNALDFLIDGTLVELLKFNGNPIGLNLPASVELTVTFTEPGVRGDSSSGSVTKPAKL
ETGLEIRVPLFIKEGEKVKVSTENRSFSGRA

Sequences:

>Translated_191_residues
MAVLIDAIDVKKRTLFELDNVPFSCLEAEVNTPTARGGQTLVRLKVRNLLTNAVFEKTFKAGEKFKEPDLQLVSASYLYS
DGSGSHFLDQESFETHTLSGEIMGNALDFLIDGTLVELLKFNGNPIGLNLPASVELTVTFTEPGVRGDSSSGSVTKPAKL
ETGLEIRVPLFIKEGEKVKVSTENRSFSGRA
>Mature_190_residues
AVLIDAIDVKKRTLFELDNVPFSCLEAEVNTPTARGGQTLVRLKVRNLLTNAVFEKTFKAGEKFKEPDLQLVSASYLYSD
GSGSHFLDQESFETHTLSGEIMGNALDFLIDGTLVELLKFNGNPIGLNLPASVELTVTFTEPGVRGDSSSGSVTKPAKLE
TGLEIRVPLFIKEGEKVKVSTENRSFSGRA

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family [H]

Homologues:

Organism=Escherichia coli, GI1790590, Length=173, Percent_Identity=35.8381502890173, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI87082061, Length=187, Percent_Identity=29.9465240641711, Blast_Score=100, Evalue=5e-23,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C [H]

EC number: NA

Molecular weight: Translated: 20784; Mature: 20653

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLIDAIDVKKRTLFELDNVPFSCLEAEVNTPTARGGQTLVRLKVRNLLTNAVFEKTFK
CEEEEEECCCCHHHEEEECCCCCEEEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHH
AGEKFKEPDLQLVSASYLYSDGSGSHFLDQESFETHTLSGEIMGNALDFLIDGTLVELLK
HCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCEEECCCHHHCCHHHHHHCHHHHHHHH
FNGNPIGLNLPASVELTVTFTEPGVRGDSSSGSVTKPAKLETGLEIRVPLFIKEGEKVKV
CCCCEEEEECCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCEEEE
STENRSFSGRA
EECCCCCCCCC
>Mature Secondary Structure 
AVLIDAIDVKKRTLFELDNVPFSCLEAEVNTPTARGGQTLVRLKVRNLLTNAVFEKTFK
EEEEEECCCCHHHEEEECCCCCEEEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHH
AGEKFKEPDLQLVSASYLYSDGSGSHFLDQESFETHTLSGEIMGNALDFLIDGTLVELLK
HCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCEEECCCHHHCCHHHHHHCHHHHHHHH
FNGNPIGLNLPASVELTVTFTEPGVRGDSSSGSVTKPAKLETGLEIRVPLFIKEGEKVKV
CCCCEEEEECCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCEEEE
STENRSFSGRA
EECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA