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The map label for this gene is atoS [C]

Identifier: 116622312

GI number: 116622312

Start: 4058727

End: 4061072

Strand: Reverse

Name: atoS [C]

Synonym: Acid_3206

Alternate gene names: 116622312

Gene position: 4061072-4058727 (Counterclockwise)

Preceding gene: 116622320

Following gene: 116622311

Centisome position: 40.75

GC content: 61.76

Gene sequence:

>2346_bases
ATGAAGGATGAGACCCTGGCCGCGTATGAGGCGGAGCGGTCGGCCGGCGATCTGCCGGCGCGCGAGGACCATTATCGAAG
CCTCTTCGAGTGCATGAACGAGGGCTTCGCGCTCTGCGAAATCCTCTGCGATGCGCTGGGAAATGTGCACGATTTCCGCT
ACCTCGCGGTCAACCCCGCCTTCGAGCGCCACACCGGGTTAAGCGCTGCCCAGGTCACCGGTCGAACCATCCTGGAACTG
TTTCCGGAGATCGAACGTGAGTGGTTCGAACAATGCGGTAAGACCGCTCTAACCGGCGTGAGCGCGCGATTTGAGGCGTG
GTTCGGCCTCTTGGGACGGTGGTTCGAAGTATCCTGCTTCCAAACTACTCCGGGCCGTTTCGGGGCCCTCTTCACCGACA
TCTCGAAGTTCAAGCGCGAGGGCACAGAGTACCGGATGGCCGGGGAGCTTCAGGCGATCCTCGAAGCCACGCCGGCGGCA
ATCTGGATCGCGCACGACCCGGAATGCCGCCGGATCACGGGCAACGCCTATGCCGACGAAGTGATCATGCGTGCCGAACG
GGGCGGCAACATCTCGCGGAGCGCGCTCCCGGGCGATGAGGCCGTATCGTACCGGGTCTACCGCAACGGAGTCGAACTAG
CTCCCGGAGAGCTGCCGTCCCAGGTAGCCGCGGCCACCGGCCAGCCGGTAAAGGAGCAGGGGTTCGAACTGGTCTTCAAC
GATGGCCGCCGCGTCCACACCACCTTAAGCGCCGTGCCGCTGTTCGACGCCGACGGCCGAGTACGCGGCTCGGTGACCGC
GGGGATCGATATCACGCGCCTGAAGCAGGCCGAAGAGACCCTGCGCGCGAGCGAAGAAAAATACCGGCTGCTATTTGAGA
GCAGCATCGATGGCATTATTCTCACCAGTCCGGACGGCTATATCTCCGCGGCCAACAGCGCAGCCTGCCGAATCCTGGGC
CGGACCGAAGAAGAGATCATTCAGGCTGGCCGGGAAGGCATCACAGATACCTCGGACCCGCGCCTCGCGGCGGCCCTGGA
AGAGCGTGACCGCACCGGACGATTCCATGGCGAACTGACCATGAAACACAAGGACGGGAGCCTGTTCCCCGCTGAAATCT
CAACCGTGTTGTATGGCGGCAAGGACAGCGAAACCCGGTCTTCGGTCCTCTTCAGGGACATCACCGAACGCAAACGGGCC
GAGGAGCGACTTCGGGAAGTTCAGAAACTGGAGAGCCTCGGATTGTTGGCGGGCGGCATCGCCCACGACTTCAATAATCT
ACTGGTCAGCGTGATCGGCAACGCGAGCCTTGCCCAGGAACGGCTCCCGGCCGGCCACCCCCTGGTCGAACTGCTGGAGC
GAGTGGTGCAGAGCGGTCACCAGGCCGCGCACCTGACCAATCAGATGCTGGCTTATTCGGGCAAGGGAAAATTCCTGGTG
GAGACTTTGAACCTCTCGGCCCTGATCGCCGATATGGGGTTTGTCGTTCAGGAGTCGATTTCCCCCAGGATCGCGATCCA
CTTCCAGCTTGAAGAAAACCTGCCGCCGATCGAAGCGGACCGCGGACAAATGAAACAAGTGTTCATGAATCTGGCAACCA
ATGCGGCGGATGCAATCGGCAGCCGCGACGGCCTGATCATCGTCAAGACCGGAATTCGGAACGTAGACGGGCAGTTCATA
CAACGGCGCCAGGAGGCGCGCGACCTCATGCCGGGACGGTACGTTTATCTGGATGTTAGCGACAGCGGGTGCGGCATGGA
CGAAGCCACCAGGGCCAGGATCTTCGACCCGTTCTACTCCACGAAATTCATGGGGCGCGGGTTGGGTCTGGCCGCGGTGG
GCGGTATCGTCCGCGGACACAAGGGCACGGTCACGGTCAGCAGCCAACCGGGCCAGGGCAGCTGCTTCACCGTACTCCTG
CCGGCGACGGAGTATGACATCGAAGAACTGGCCCCCGGACTCGGCGACGCACTGCCTAAAAGCCCCGGCACGATTTTGGT
CGTGGACGATGAACGGATGGTAAGAGATCTGGTGAAGCAGGCGCTCGAAGATCACGGATATACGGTTCTGCTGGCCGAAA
GCGGGCCTATGGCAATCGACGTAATGAAGTCGCGGCCCGGCGGCATCGATCTCGTCCTCCTGGATCTCAGCATGCCTGGG
ATGAGCGGCGCGGAAGTCCTGCCCGAGATCAGAAAGATACTGCCGGATGTCAAGGTGATGCTCTCGAGCGGGTACAGCGA
GGCCGAATCGATGCAGATGTTCGAAGGCCAGCAGGTTTCCGCATTCCTCCAGAAACCCTTCACCCTGAACACGCTCCGGG
ATGCCGTGAAGGACTGCATCGGTTAG

Upstream 100 bases:

>100_bases
TGGCAACCCGTGACTTTTCGGGCTTGGCGGAACGCTGTTCAGCCGGCCTCGTGTCCTGTTCAGGTGCGCGTGCGGGCTGC
TATGCGATGTGACGTTCGTT

Downstream 100 bases:

>100_bases
CGCGCGATTGCCGTTGCACGCTGTGATATGCTAATCGGCCTGATCGGGAGGGGAAGATGGATTTCACAGCTCTTCGTTCG
GATTTCAGCGGGGAGATTCT

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 781; Mature: 781

Protein sequence:

>781_residues
MKDETLAAYEAERSAGDLPAREDHYRSLFECMNEGFALCEILCDALGNVHDFRYLAVNPAFERHTGLSAAQVTGRTILEL
FPEIEREWFEQCGKTALTGVSARFEAWFGLLGRWFEVSCFQTTPGRFGALFTDISKFKREGTEYRMAGELQAILEATPAA
IWIAHDPECRRITGNAYADEVIMRAERGGNISRSALPGDEAVSYRVYRNGVELAPGELPSQVAAATGQPVKEQGFELVFN
DGRRVHTTLSAVPLFDADGRVRGSVTAGIDITRLKQAEETLRASEEKYRLLFESSIDGIILTSPDGYISAANSAACRILG
RTEEEIIQAGREGITDTSDPRLAAALEERDRTGRFHGELTMKHKDGSLFPAEISTVLYGGKDSETRSSVLFRDITERKRA
EERLREVQKLESLGLLAGGIAHDFNNLLVSVIGNASLAQERLPAGHPLVELLERVVQSGHQAAHLTNQMLAYSGKGKFLV
ETLNLSALIADMGFVVQESISPRIAIHFQLEENLPPIEADRGQMKQVFMNLATNAADAIGSRDGLIIVKTGIRNVDGQFI
QRRQEARDLMPGRYVYLDVSDSGCGMDEATRARIFDPFYSTKFMGRGLGLAAVGGIVRGHKGTVTVSSQPGQGSCFTVLL
PATEYDIEELAPGLGDALPKSPGTILVVDDERMVRDLVKQALEDHGYTVLLAESGPMAIDVMKSRPGGIDLVLLDLSMPG
MSGAEVLPEIRKILPDVKVMLSSGYSEAESMQMFEGQQVSAFLQKPFTLNTLRDAVKDCIG

Sequences:

>Translated_781_residues
MKDETLAAYEAERSAGDLPAREDHYRSLFECMNEGFALCEILCDALGNVHDFRYLAVNPAFERHTGLSAAQVTGRTILEL
FPEIEREWFEQCGKTALTGVSARFEAWFGLLGRWFEVSCFQTTPGRFGALFTDISKFKREGTEYRMAGELQAILEATPAA
IWIAHDPECRRITGNAYADEVIMRAERGGNISRSALPGDEAVSYRVYRNGVELAPGELPSQVAAATGQPVKEQGFELVFN
DGRRVHTTLSAVPLFDADGRVRGSVTAGIDITRLKQAEETLRASEEKYRLLFESSIDGIILTSPDGYISAANSAACRILG
RTEEEIIQAGREGITDTSDPRLAAALEERDRTGRFHGELTMKHKDGSLFPAEISTVLYGGKDSETRSSVLFRDITERKRA
EERLREVQKLESLGLLAGGIAHDFNNLLVSVIGNASLAQERLPAGHPLVELLERVVQSGHQAAHLTNQMLAYSGKGKFLV
ETLNLSALIADMGFVVQESISPRIAIHFQLEENLPPIEADRGQMKQVFMNLATNAADAIGSRDGLIIVKTGIRNVDGQFI
QRRQEARDLMPGRYVYLDVSDSGCGMDEATRARIFDPFYSTKFMGRGLGLAAVGGIVRGHKGTVTVSSQPGQGSCFTVLL
PATEYDIEELAPGLGDALPKSPGTILVVDDERMVRDLVKQALEDHGYTVLLAESGPMAIDVMKSRPGGIDLVLLDLSMPG
MSGAEVLPEIRKILPDVKVMLSSGYSEAESMQMFEGQQVSAFLQKPFTLNTLRDAVKDCIG
>Mature_781_residues
MKDETLAAYEAERSAGDLPAREDHYRSLFECMNEGFALCEILCDALGNVHDFRYLAVNPAFERHTGLSAAQVTGRTILEL
FPEIEREWFEQCGKTALTGVSARFEAWFGLLGRWFEVSCFQTTPGRFGALFTDISKFKREGTEYRMAGELQAILEATPAA
IWIAHDPECRRITGNAYADEVIMRAERGGNISRSALPGDEAVSYRVYRNGVELAPGELPSQVAAATGQPVKEQGFELVFN
DGRRVHTTLSAVPLFDADGRVRGSVTAGIDITRLKQAEETLRASEEKYRLLFESSIDGIILTSPDGYISAANSAACRILG
RTEEEIIQAGREGITDTSDPRLAAALEERDRTGRFHGELTMKHKDGSLFPAEISTVLYGGKDSETRSSVLFRDITERKRA
EERLREVQKLESLGLLAGGIAHDFNNLLVSVIGNASLAQERLPAGHPLVELLERVVQSGHQAAHLTNQMLAYSGKGKFLV
ETLNLSALIADMGFVVQESISPRIAIHFQLEENLPPIEADRGQMKQVFMNLATNAADAIGSRDGLIIVKTGIRNVDGQFI
QRRQEARDLMPGRYVYLDVSDSGCGMDEATRARIFDPFYSTKFMGRGLGLAAVGGIVRGHKGTVTVSSQPGQGSCFTVLL
PATEYDIEELAPGLGDALPKSPGTILVVDDERMVRDLVKQALEDHGYTVLLAESGPMAIDVMKSRPGGIDLVLLDLSMPG
MSGAEVLPEIRKILPDVKVMLSSGYSEAESMQMFEGQQVSAFLQKPFTLNTLRDAVKDCIG

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=367, Percent_Identity=27.2479564032698, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1790436, Length=253, Percent_Identity=32.4110671936759, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI48994928, Length=547, Percent_Identity=24.6800731261426, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI1790300, Length=250, Percent_Identity=25.6, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI145693157, Length=290, Percent_Identity=23.7931034482759, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1786912, Length=263, Percent_Identity=27.3764258555133, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788713, Length=267, Percent_Identity=24.3445692883895, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI87081816, Length=394, Percent_Identity=22.0812182741117, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 85452; Mature: 85452

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDETLAAYEAERSAGDLPAREDHYRSLFECMNEGFALCEILCDALGNVHDFRYLAVNPA
CCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECCC
FERHTGLSAAQVTGRTILELFPEIEREWFEQCGKTALTGVSARFEAWFGLLGRWFEVSCF
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHEEEEE
QTTPGRFGALFTDISKFKREGTEYRMAGELQAILEATPAAIWIAHDPECRRITGNAYADE
ECCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCEEEEECCCCCCEECCCHHHHH
VIMRAERGGNISRSALPGDEAVSYRVYRNGVELAPGELPSQVAAATGQPVKEQGFELVFN
HHHHHHCCCCCCCCCCCCCHHEEEEEECCCCCCCCCCCCHHHHHHCCCCHHHCCCEEEEC
DGRRVHTTLSAVPLFDADGRVRGSVTAGIDITRLKQAEETLRASEEKYRLLFESSIDGII
CCCEEEEEEEECEEECCCCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHEECCCCEEE
LTSPDGYISAANSAACRILGRTEEEIIQAGREGITDTSDPRLAAALEERDRTGRFHGELT
EECCCCCEECCCCHHEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEECEEE
MKHKDGSLFPAEISTVLYGGKDSETRSSVLFRDITERKRAEERLREVQKLESLGLLAGGI
EEECCCCCCHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHDFNNLLVSVIGNASLAQERLPAGHPLVELLERVVQSGHQAAHLTNQMLAYSGKGKFLV
HHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEE
ETLNLSALIADMGFVVQESISPRIAIHFQLEENLPPIEADRGQMKQVFMNLATNAADAIG
EEHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
SRDGLIIVKTGIRNVDGQFIQRRQEARDLMPGRYVYLDVSDSGCGMDEATRARIFDPFYS
CCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHCCCHHH
TKFMGRGLGLAAVGGIVRGHKGTVTVSSQPGQGSCFTVLLPATEYDIEELAPGLGDALPK
HHHHCCCCCHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCCHHHHCCCCCCCCCC
SPGTILVVDDERMVRDLVKQALEDHGYTVLLAESGPMAIDVMKSRPGGIDLVLLDLSMPG
CCCEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCEEEEEEEECCCC
MSGAEVLPEIRKILPDVKVMLSSGYSEAESMQMFEGQQVSAFLQKPFTLNTLRDAVKDCI
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHC
G
C
>Mature Secondary Structure
MKDETLAAYEAERSAGDLPAREDHYRSLFECMNEGFALCEILCDALGNVHDFRYLAVNPA
CCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECCC
FERHTGLSAAQVTGRTILELFPEIEREWFEQCGKTALTGVSARFEAWFGLLGRWFEVSCF
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHEEEEE
QTTPGRFGALFTDISKFKREGTEYRMAGELQAILEATPAAIWIAHDPECRRITGNAYADE
ECCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCEEEEECCCCCCEECCCHHHHH
VIMRAERGGNISRSALPGDEAVSYRVYRNGVELAPGELPSQVAAATGQPVKEQGFELVFN
HHHHHHCCCCCCCCCCCCCHHEEEEEECCCCCCCCCCCCHHHHHHCCCCHHHCCCEEEEC
DGRRVHTTLSAVPLFDADGRVRGSVTAGIDITRLKQAEETLRASEEKYRLLFESSIDGII
CCCEEEEEEEECEEECCCCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHEECCCCEEE
LTSPDGYISAANSAACRILGRTEEEIIQAGREGITDTSDPRLAAALEERDRTGRFHGELT
EECCCCCEECCCCHHEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEECEEE
MKHKDGSLFPAEISTVLYGGKDSETRSSVLFRDITERKRAEERLREVQKLESLGLLAGGI
EEECCCCCCHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHDFNNLLVSVIGNASLAQERLPAGHPLVELLERVVQSGHQAAHLTNQMLAYSGKGKFLV
HHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEE
ETLNLSALIADMGFVVQESISPRIAIHFQLEENLPPIEADRGQMKQVFMNLATNAADAIG
EEHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
SRDGLIIVKTGIRNVDGQFIQRRQEARDLMPGRYVYLDVSDSGCGMDEATRARIFDPFYS
CCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHCCCHHH
TKFMGRGLGLAAVGGIVRGHKGTVTVSSQPGQGSCFTVLLPATEYDIEELAPGLGDALPK
HHHHCCCCCHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCCHHHHCCCCCCCCCC
SPGTILVVDDERMVRDLVKQALEDHGYTVLLAESGPMAIDVMKSRPGGIDLVLLDLSMPG
CCCEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCEEEEEEEECCCC
MSGAEVLPEIRKILPDVKVMLSSGYSEAESMQMFEGQQVSAFLQKPFTLNTLRDAVKDCI
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA