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The map label for this gene is mmgC [H]

Identifier: 116622186

GI number: 116622186

Start: 3893602

End: 3895290

Strand: Reverse

Name: mmgC [H]

Synonym: Acid_3078

Alternate gene names: 116622186

Gene position: 3895290-3893602 (Counterclockwise)

Preceding gene: 116622187

Following gene: 116622185

Centisome position: 39.09

GC content: 64.0

Gene sequence:

>1689_bases
ATGATTACGGGGAAGACATTAAAGCTCAGCTTGAAATCGCTGCGGGAGTTCGCCAAGAAGCGATTGCCCGACCAGGAGTT
GATCGCGCTGGATGCACGGGACGAGTGCCCGCTCGAGATCGTGCGGCACATGTGCAGTCCGGATAAACTCGGGATCCAAC
TGCTGTTCATCCCGGAGGAATACGGCGGCTTTGGCGGCGGCGCGTTCGATGTGTACTGCGTGTGCGAGGAGATGGCGAGA
ATCGACCTGGGCATCGCGACTGCTGTGCTGGCGACCTTTCTAGGCAGCGACCCGATTACGGTGGGGGCCACGCCGGAGCA
GAAGAAGATCTGGCTTTCGCGGATTGCGGAAGAAGGAATTCTCTTCGCTTACGGCGCAACCGAGCCCGACGCGGGCAGCG
ACCTGGGGGCATTGCAGACTACGGCCGACCGCGTGCTCGAAGGCGAGCGGGTGGTGGGTTATCGCATCAACGGAAGCAAG
CAGTGGATCAGTAACGGCGGCATCGCCGATGCGTACACAGTGCTGGCGAATACGCCGACGGGACCGAGCTGGTTCATTGT
GGACCGCGGCGCGCAGGGATTCACGCAGGGCAGGCCGGAGGATAAGCATGGAATCCGACTGAGCAATACCGCGGCACTCT
CATTCACCGACGTGACTGTACCGGCCGATCGACTGGTCGGCGGCGTCGAAGGGCAGGGGTTGCTGCAGGCTCAGGCCGTC
TTCGGTTACACGCGGCTGATGGTGGCGGCATTCGGATTGGGCGCGGGATGGGCGGCACTGGACCGCGCGATCCCTTACTC
GGCGAAACGAATTCAGGCCGGCACACCGCTATCCGAGAAGCAAGGATACACGCACAAGCTAATCGTTCCGCACGTGGTCC
GGCTGGAGGCGGCGCGCGCTTCCATTGAAGAGACGGCCGCGCGTATCGACGCCGGAGAGGGCAGCCTGAATACCGAGGGC
GCGATCGCCAAGTACATGGCCACCGAGGCCGGCAATGCGGCGGCCGAGGCAGCGATTCAGGCGCTGGGCGGATACGGCTA
TACGCACGAGTACCTGGTGGAGAAGATCAGCCGGGATGTTCGCATCACGATCATCTACGAGGGCACTTCGGAGATTATGG
AGATGACGATCAGCCGCGACCGGTGGCAACTGCATCTCAAGACGCGCGGCAAGCACTATCACGACCAGGCTCGCGAACTC
GAAGCGCTCCATGCCGCGCATCCTAATGTGGGAGCGGGCTGCGCGGGGCTCGTCATGCATGCGCTCGCCGAAGTAATGGA
GCGAGCCCGGGCCGGACGCCTGACGCGCGATCAGCACATCCTGCTGCGCATGGGCGAGTGGATCGCGTATGCGGAATCCG
CCGGGAGCCTGGCGCGGCGCGCGGCGCTGCTCGAAGAAGGAAAGCTCTCCGAAAAGGCGAGTCAGCGATTCGATGCTGTT
TCGCTGGCGGCAATTTCGCGGATCTTCGCGCGTGAGGCGGCGCTCCGGGTGGCGCAGGAAGGGCTGCGGTGGATTGCGGG
CGCCGGGACGGATGCGGCGGCCGGCGGCGAAGGAGATCTCGCCGCGCTGGAAGCCTCGCTGAATTTCGCGGCCATCCATC
GCGCCCAACGCGGTCTCATCGCCGATATGGATTTTGTTGCCGACGTGCTCTACGGACGCGCCTCAAAGGCCGCCGGGCAC
GCCGCTTGA

Upstream 100 bases:

>100_bases
CCGATGTGGGGATCGTAGACGACCTGCTGGAGTTTCTTCCGGCGCTGGCAAATCGGGTTCGCGAGGAGAGTTGTGTACCG
GGCAATGAAAGGCGGCGGTC

Downstream 100 bases:

>100_bases
GCCGCGGCTAAGGGCAGCGGTGAAGGAGCCTCGTCATGCAGGACACAGCTTATCGAGCAATCGCGATTGTAGGGGCAGGC
GCCGTTCTGCCCGATGCCCC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 562; Mature: 562

Protein sequence:

>562_residues
MITGKTLKLSLKSLREFAKKRLPDQELIALDARDECPLEIVRHMCSPDKLGIQLLFIPEEYGGFGGGAFDVYCVCEEMAR
IDLGIATAVLATFLGSDPITVGATPEQKKIWLSRIAEEGILFAYGATEPDAGSDLGALQTTADRVLEGERVVGYRINGSK
QWISNGGIADAYTVLANTPTGPSWFIVDRGAQGFTQGRPEDKHGIRLSNTAALSFTDVTVPADRLVGGVEGQGLLQAQAV
FGYTRLMVAAFGLGAGWAALDRAIPYSAKRIQAGTPLSEKQGYTHKLIVPHVVRLEAARASIEETAARIDAGEGSLNTEG
AIAKYMATEAGNAAAEAAIQALGGYGYTHEYLVEKISRDVRITIIYEGTSEIMEMTISRDRWQLHLKTRGKHYHDQAREL
EALHAAHPNVGAGCAGLVMHALAEVMERARAGRLTRDQHILLRMGEWIAYAESAGSLARRAALLEEGKLSEKASQRFDAV
SLAAISRIFAREAALRVAQEGLRWIAGAGTDAAAGGEGDLAALEASLNFAAIHRAQRGLIADMDFVADVLYGRASKAAGH
AA

Sequences:

>Translated_562_residues
MITGKTLKLSLKSLREFAKKRLPDQELIALDARDECPLEIVRHMCSPDKLGIQLLFIPEEYGGFGGGAFDVYCVCEEMAR
IDLGIATAVLATFLGSDPITVGATPEQKKIWLSRIAEEGILFAYGATEPDAGSDLGALQTTADRVLEGERVVGYRINGSK
QWISNGGIADAYTVLANTPTGPSWFIVDRGAQGFTQGRPEDKHGIRLSNTAALSFTDVTVPADRLVGGVEGQGLLQAQAV
FGYTRLMVAAFGLGAGWAALDRAIPYSAKRIQAGTPLSEKQGYTHKLIVPHVVRLEAARASIEETAARIDAGEGSLNTEG
AIAKYMATEAGNAAAEAAIQALGGYGYTHEYLVEKISRDVRITIIYEGTSEIMEMTISRDRWQLHLKTRGKHYHDQAREL
EALHAAHPNVGAGCAGLVMHALAEVMERARAGRLTRDQHILLRMGEWIAYAESAGSLARRAALLEEGKLSEKASQRFDAV
SLAAISRIFAREAALRVAQEGLRWIAGAGTDAAAGGEGDLAALEASLNFAAIHRAQRGLIADMDFVADVLYGRASKAAGH
AA
>Mature_562_residues
MITGKTLKLSLKSLREFAKKRLPDQELIALDARDECPLEIVRHMCSPDKLGIQLLFIPEEYGGFGGGAFDVYCVCEEMAR
IDLGIATAVLATFLGSDPITVGATPEQKKIWLSRIAEEGILFAYGATEPDAGSDLGALQTTADRVLEGERVVGYRINGSK
QWISNGGIADAYTVLANTPTGPSWFIVDRGAQGFTQGRPEDKHGIRLSNTAALSFTDVTVPADRLVGGVEGQGLLQAQAV
FGYTRLMVAAFGLGAGWAALDRAIPYSAKRIQAGTPLSEKQGYTHKLIVPHVVRLEAARASIEETAARIDAGEGSLNTEG
AIAKYMATEAGNAAAEAAIQALGGYGYTHEYLVEKISRDVRITIIYEGTSEIMEMTISRDRWQLHLKTRGKHYHDQAREL
EALHAAHPNVGAGCAGLVMHALAEVMERARAGRLTRDQHILLRMGEWIAYAESAGSLARRAALLEEGKLSEKASQRFDAV
SLAAISRIFAREAALRVAQEGLRWIAGAGTDAAAGGEGDLAALEASLNFAAIHRAQRGLIADMDFVADVLYGRASKAAGH
AA

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557231, Length=378, Percent_Identity=35.978835978836, Blast_Score=200, Evalue=3e-51,
Organism=Homo sapiens, GI187960098, Length=378, Percent_Identity=35.978835978836, Blast_Score=200, Evalue=3e-51,
Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=34.4919786096257, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI4557233, Length=383, Percent_Identity=35.509138381201, Blast_Score=163, Evalue=4e-40,
Organism=Homo sapiens, GI21361497, Length=366, Percent_Identity=32.5136612021858, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI4557235, Length=386, Percent_Identity=32.1243523316062, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI76496475, Length=386, Percent_Identity=32.1243523316062, Blast_Score=157, Evalue=4e-38,
Organism=Homo sapiens, GI4501857, Length=389, Percent_Identity=30.0771208226221, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI7656849, Length=358, Percent_Identity=30.1675977653631, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI226958412, Length=339, Percent_Identity=30.0884955752212, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI226958414, Length=339, Percent_Identity=30.0884955752212, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI4503943, Length=370, Percent_Identity=25.4054054054054, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI7669494, Length=374, Percent_Identity=24.8663101604278, Blast_Score=93, Evalue=6e-19,
Organism=Escherichia coli, GI1786223, Length=349, Percent_Identity=28.3667621776504, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI87081958, Length=379, Percent_Identity=28.4960422163588, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI87082384, Length=326, Percent_Identity=26.3803680981595, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17534899, Length=368, Percent_Identity=38.3152173913043, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17570075, Length=394, Percent_Identity=35.7868020304569, Blast_Score=195, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI17569725, Length=358, Percent_Identity=37.1508379888268, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17508101, Length=330, Percent_Identity=36.6666666666667, Blast_Score=170, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17506239, Length=335, Percent_Identity=34.9253731343284, Blast_Score=157, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71985184, Length=383, Percent_Identity=29.7650130548303, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17533517, Length=376, Percent_Identity=28.4574468085106, Blast_Score=139, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17538396, Length=375, Percent_Identity=30.6666666666667, Blast_Score=131, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI71990804, Length=286, Percent_Identity=34.2657342657343, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI71985192, Length=310, Percent_Identity=29.0322580645161, Blast_Score=115, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17505929, Length=348, Percent_Identity=31.3218390804598, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=35.0649350649351, Blast_Score=111, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17551932, Length=349, Percent_Identity=29.2263610315186, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17534353, Length=384, Percent_Identity=26.8229166666667, Blast_Score=101, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI71982178, Length=229, Percent_Identity=32.7510917030568, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17531909, Length=247, Percent_Identity=30.7692307692308, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24660351, Length=385, Percent_Identity=36.3636363636364, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI281363737, Length=401, Percent_Identity=33.4164588528678, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24666513, Length=386, Percent_Identity=32.9015544041451, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI21356377, Length=385, Percent_Identity=33.7662337662338, Blast_Score=155, Evalue=6e-38,
Organism=Drosophila melanogaster, GI24646207, Length=386, Percent_Identity=34.1968911917098, Blast_Score=148, Evalue=8e-36,
Organism=Drosophila melanogaster, GI21355753, Length=328, Percent_Identity=33.5365853658537, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI19920834, Length=332, Percent_Identity=27.4096385542169, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 60197; Mature: 60197

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITGKTLKLSLKSLREFAKKRLPDQELIALDARDECPLEIVRHMCSPDKLGIQLLFIPEE
CCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEEEEEHH
YGGFGGGAFDVYCVCEEMARIDLGIATAVLATFLGSDPITVGATPEQKKIWLSRIAEEGI
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCE
LFAYGATEPDAGSDLGALQTTADRVLEGERVVGYRINGSKQWISNGGIADAYTVLANTPT
EEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCHHHHCCCCCCHHEEEEECCCC
GPSWFIVDRGAQGFTQGRPEDKHGIRLSNTAALSFTDVTVPADRLVGGVEGQGLLQAQAV
CCEEEEEECCCCCCCCCCCCCCCCEEEECCEEEEEEEEECCHHHHHCCCCCCCHHHHHHH
FGYTRLMVAAFGLGAGWAALDRAIPYSAKRIQAGTPLSEKQGYTHKLIVPHVVRLEAARA
HHHHHHHHHHHCCCCCHHHHHHCCCCCHHHCCCCCCCHHCCCCEEEEHHHHHHHHHHHHH
SIEETAARIDAGEGSLNTEGAIAKYMATEAGNAAAEAAIQALGGYGYTHEYLVEKISRDV
HHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCE
RITIIYEGTSEIMEMTISRDRWQLHLKTRGKHYHDQARELEALHAAHPNVGAGCAGLVMH
EEEEEECCHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHH
ALAEVMERARAGRLTRDQHILLRMGEWIAYAESAGSLARRAALLEEGKLSEKASQRFDAV
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
SLAAISRIFAREAALRVAQEGLRWIAGAGTDAAAGGEGDLAALEASLNFAAIHRAQRGLI
HHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHHHCCHHHHHHHHHCCCH
ADMDFVADVLYGRASKAAGHAA
HHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MITGKTLKLSLKSLREFAKKRLPDQELIALDARDECPLEIVRHMCSPDKLGIQLLFIPEE
CCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEEEEEHH
YGGFGGGAFDVYCVCEEMARIDLGIATAVLATFLGSDPITVGATPEQKKIWLSRIAEEGI
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCE
LFAYGATEPDAGSDLGALQTTADRVLEGERVVGYRINGSKQWISNGGIADAYTVLANTPT
EEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCHHHHCCCCCCHHEEEEECCCC
GPSWFIVDRGAQGFTQGRPEDKHGIRLSNTAALSFTDVTVPADRLVGGVEGQGLLQAQAV
CCEEEEEECCCCCCCCCCCCCCCCEEEECCEEEEEEEEECCHHHHHCCCCCCCHHHHHHH
FGYTRLMVAAFGLGAGWAALDRAIPYSAKRIQAGTPLSEKQGYTHKLIVPHVVRLEAARA
HHHHHHHHHHHCCCCCHHHHHHCCCCCHHHCCCCCCCHHCCCCEEEEHHHHHHHHHHHHH
SIEETAARIDAGEGSLNTEGAIAKYMATEAGNAAAEAAIQALGGYGYTHEYLVEKISRDV
HHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCE
RITIIYEGTSEIMEMTISRDRWQLHLKTRGKHYHDQARELEALHAAHPNVGAGCAGLVMH
EEEEEECCHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHH
ALAEVMERARAGRLTRDQHILLRMGEWIAYAESAGSLARRAALLEEGKLSEKASQRFDAV
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
SLAAISRIFAREAALRVAQEGLRWIAGAGTDAAAGGEGDLAALEASLNFAAIHRAQRGLI
HHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHHHCCHHHHHHHHHCCCH
ADMDFVADVLYGRASKAAGHAA
HHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]