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The map label for this gene is ndhL [H]

Identifier: 116622036

GI number: 116622036

Start: 3701254

End: 3702114

Strand: Direct

Name: ndhL [H]

Synonym: Acid_2921

Alternate gene names: 116622036

Gene position: 3701254-3702114 (Clockwise)

Preceding gene: 116622035

Following gene: 116622037

Centisome position: 37.14

GC content: 61.9

Gene sequence:

>861_bases
GTGGCTGATCTCGACGATCTTCTTGACCAGGATGCACCCGTGTCCTCACCGGCCGATTCGGATTTCGCTTGGCCGGCCAA
TCCTACGGTTCTAGGCACGCGCGTCAAACGCCTGGACGGGCCCGATAAGGTGACCGGCCGTGCCAAGTACACCTTCGACA
TTGCGCGCCCGCGAATGCTGTATGCGCGCATTGTCCGCTCGCCATATCCACACGCGCGCGTTGTGTCGGTGGACCTGTCG
GTGGCGAATCGCATGCCGGGCGTTAAGGCCTCGCTCGTCTCGAAGGACCCGGCGGGCCAGAACAATCGCGTGATGTTTCA
GGGCGATGAGGTGGCTGCCGTGGCAGCCGATACCGAGGAGCATGCCATCGACGCGGCGCGTGCCATTAAGGTGGAGTATG
AAATCCAGCCGCACGTGACAATCGAGGAAAAGGCGCTGGCAGGCACGGCGCCACAGGTCTTCACAGGTGGGAATGTTCGC
GCCGGCCAGCCGCAGCAAAGCGGTGATATCGCGGCAGGCTTTCAGGCTGCGGCTGTACCAAATTTGAGCCTCACGCATAA
AATTGAATCTGGATCGCTGGACCACCTTGGCCGACCTCGCAGGCTGTCGGTCCCGAAGAAGATGGTTGCGCCAAACACCC
GCTCAAATGCCCCGACCAGCCGGCGGTACTCTTTGCCGCCGGTCTGCATTCCGAACGTCTCCAGCATTTCGGCAGCGGTG
CGGAAGCGAATGGTTTGGCTCTTCTGCTGGACGGCGAGGGTCGCCAGGAAGATCGGCACCAAGCGGTCCTGGCCGAATGG
GACGCCGAATTCAGGGTGCCCGGTCACCTGCAGTACGAACTTGCCATTCCGACGCTCATAG

Upstream 100 bases:

>100_bases
ACGCCCGAACAAATCAAGAAAGGCCTCGACGGCAACATTTGTCGGTGCGGCACATTTACCCGCATCTTCGAAGCCGTTTC
CAGTGTGAAAGGGGGACAGC

Downstream 100 bases:

>100_bases
AGCAACTGATCCTTGGGCAGCCGGCGGACAGGAAGACCGCACAGTACGAATGGTCTCCAACTGAAGCACAGAGTCTGGGT
CGCCTGGTCGCGATTCTGCC

Product: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead

Products: NA

Alternate protein names: NDH; Nicotinic acid hydroxylase large molybdopterin subunit; NAH [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MADLDDLLDQDAPVSSPADSDFAWPANPTVLGTRVKRLDGPDKVTGRAKYTFDIARPRMLYARIVRSPYPHARVVSVDLS
VANRMPGVKASLVSKDPAGQNNRVMFQGDEVAAVAADTEEHAIDAARAIKVEYEIQPHVTIEEKALAGTAPQVFTGGNVR
AGQPQQSGDIAAGFQAAAVPNLSLTHKIESGSLDHLGRPRRLSVPKKMVAPNTRSNAPTSRRYSLPPVCIPNVSSISAAV
RKRMVWLFCWTARVARKIGTKRSWPNGTPNSGCPVTCSTNLPFRRS

Sequences:

>Translated_286_residues
MADLDDLLDQDAPVSSPADSDFAWPANPTVLGTRVKRLDGPDKVTGRAKYTFDIARPRMLYARIVRSPYPHARVVSVDLS
VANRMPGVKASLVSKDPAGQNNRVMFQGDEVAAVAADTEEHAIDAARAIKVEYEIQPHVTIEEKALAGTAPQVFTGGNVR
AGQPQQSGDIAAGFQAAAVPNLSLTHKIESGSLDHLGRPRRLSVPKKMVAPNTRSNAPTSRRYSLPPVCIPNVSSISAAV
RKRMVWLFCWTARVARKIGTKRSWPNGTPNSGCPVTCSTNLPFRRS
>Mature_285_residues
ADLDDLLDQDAPVSSPADSDFAWPANPTVLGTRVKRLDGPDKVTGRAKYTFDIARPRMLYARIVRSPYPHARVVSVDLSV
ANRMPGVKASLVSKDPAGQNNRVMFQGDEVAAVAADTEEHAIDAARAIKVEYEIQPHVTIEEKALAGTAPQVFTGGNVRA
GQPQQSGDIAAGFQAAAVPNLSLTHKIESGSLDHLGRPRRLSVPKKMVAPNTRSNAPTSRRYSLPPVCIPNVSSISAAVR
KRMVWLFCWTARVARKIGTKRSWPNGTPNSGCPVTCSTNLPFRRS

Specific function: Catalyzes the hydroxylation of nicotinate to 6- hydroxynicotinate. Also active against 2-pyrazinecarboxylic acid, but inactive against other nicotinate analogs [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789230, Length=165, Percent_Identity=33.9393939393939, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789246, Length=145, Percent_Identity=32.4137931034483, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.5 [H]

Molecular weight: Translated: 30929; Mature: 30797

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLDDLLDQDAPVSSPADSDFAWPANPTVLGTRVKRLDGPDKVTGRAKYTFDIARPRML
CCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEHHHHHHCCCCCCCCCCEEEEEECCCHHHH
YARIVRSPYPHARVVSVDLSVANRMPGVKASLVSKDPAGQNNRVMFQGDEVAAVAADTEE
HHHHHHCCCCCCEEEEEEHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCEEEEECCCHH
HAIDAARAIKVEYEIQPHVTIEEKALAGTAPQVFTGGNVRAGQPQQSGDIAAGFQAAAVP
HHHHHEEEEEEEEEECCCEEECCHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHCCC
NLSLTHKIESGSLDHLGRPRRLSVPKKMVAPNTRSNAPTSRRYSLPPVCIPNVSSISAAV
CCEEEEEECCCCHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
RKRMVWLFCWTARVARKIGTKRSWPNGTPNSGCPVTCSTNLPFRRS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCC
>Mature Secondary Structure 
ADLDDLLDQDAPVSSPADSDFAWPANPTVLGTRVKRLDGPDKVTGRAKYTFDIARPRML
CCHHHHHCCCCCCCCCCCCCCCCCCCCCEEHHHHHHCCCCCCCCCCEEEEEECCCHHHH
YARIVRSPYPHARVVSVDLSVANRMPGVKASLVSKDPAGQNNRVMFQGDEVAAVAADTEE
HHHHHHCCCCCCEEEEEEHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCEEEEECCCHH
HAIDAARAIKVEYEIQPHVTIEEKALAGTAPQVFTGGNVRAGQPQQSGDIAAGFQAAAVP
HHHHHEEEEEEEEEECCCEEECCHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHCCC
NLSLTHKIESGSLDHLGRPRRLSVPKKMVAPNTRSNAPTSRRYSLPPVCIPNVSSISAAV
CCEEEEEECCCCHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
RKRMVWLFCWTARVARKIGTKRSWPNGTPNSGCPVTCSTNLPFRRS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA