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The map label for this gene is nudG [H]

Identifier: 116621926

GI number: 116621926

Start: 3561727

End: 3562128

Strand: Reverse

Name: nudG [H]

Synonym: Acid_2811

Alternate gene names: 116621926

Gene position: 3562128-3561727 (Counterclockwise)

Preceding gene: 116621928

Following gene: 116621925

Centisome position: 35.74

GC content: 61.44

Gene sequence:

>402_bases
ATGGTTCAGGTGGTGGCGGCGATCATCGAGCGGGCGGGCGCGATTCTGGTGGGGCAGCGGACGGCGCAGCAATCGCATCC
TTTGAAGTGGGAGTTTCCCGGGGGGAAGGTCGAGCCCGGTGAAAGCCCCGAACAGGCCTTGGCGCGCGAACTCGAAGAGG
AGCTCGGAATCCGCGCCGCCGCGGGCGACGAACTGACGCGCTATCAGTATCGTTATCCCGGCAGGAGTCCCATAGAGCTA
ATCTTCGTGCGCGTGCTCAGCTTCGAGGGCGAACCTGCCAACTTGATTTTCCACGAATTGCGCTGGCATCCCAAGCGCGA
ATTGCGCGGCCTGGATTTCGTCGAAGGCGACCGCCCCTTTCTCGACGGCATCTATACTAGTGCCTATGGCAACAGCGATT
AA

Upstream 100 bases:

>100_bases
TGCATGGCGGCGCAGGGCGGCAGCGGCGGGTCTGCCTCCACGTACGCAATAGCCTCTTCGAGATTCATACGGTCCGCTTC
CTGTATGGTCCAATATTGAC

Downstream 100 bases:

>100_bases
CAGAGTCGATCCCGCCGAGAATGAATTTCTAGCCAGCCTGGAGGCCAAATCAAAACAGGCAAACTCCTTCTTGCGGGCGA
TGGCGAACCGCCCCGAAGCG

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MVQVVAAIIERAGAILVGQRTAQQSHPLKWEFPGGKVEPGESPEQALARELEEELGIRAAAGDELTRYQYRYPGRSPIEL
IFVRVLSFEGEPANLIFHELRWHPKRELRGLDFVEGDRPFLDGIYTSAYGNSD

Sequences:

>Translated_133_residues
MVQVVAAIIERAGAILVGQRTAQQSHPLKWEFPGGKVEPGESPEQALARELEEELGIRAAAGDELTRYQYRYPGRSPIEL
IFVRVLSFEGEPANLIFHELRWHPKRELRGLDFVEGDRPFLDGIYTSAYGNSD
>Mature_133_residues
MVQVVAAIIERAGAILVGQRTAQQSHPLKWEFPGGKVEPGESPEQALARELEEELGIRAAAGDELTRYQYRYPGRSPIEL
IFVRVLSFEGEPANLIFHELRWHPKRELRGLDFVEGDRPFLDGIYTSAYGNSD

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=126, Percent_Identity=42.8571428571429, Blast_Score=82, Evalue=9e-18,
Organism=Escherichia coli, GI1786288, Length=121, Percent_Identity=35.5371900826446, Blast_Score=64, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-

Molecular weight: Translated: 14993; Mature: 14993

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQVVAAIIERAGAILVGQRTAQQSHPLKWEFPGGKVEPGESPEQALARELEEELGIRAA
CHHHHHHHHHHCCEEEECCCCHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCC
AGDELTRYQYRYPGRSPIELIFVRVLSFEGEPANLIFHELRWHPKRELRGLDFVEGDRPF
CCCCHHHEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHCCCCCCCCCCCCH
LDGIYTSAYGNSD
HHHHHHCCCCCCC
>Mature Secondary Structure
MVQVVAAIIERAGAILVGQRTAQQSHPLKWEFPGGKVEPGESPEQALARELEEELGIRAA
CHHHHHHHHHHCCEEEECCCCHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCC
AGDELTRYQYRYPGRSPIELIFVRVLSFEGEPANLIFHELRWHPKRELRGLDFVEGDRPF
CCCCHHHEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHCCCCCCCCCCCCH
LDGIYTSAYGNSD
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]