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The map label for this gene is macB [H]

Identifier: 116621928

GI number: 116621928

Start: 3562664

End: 3565078

Strand: Reverse

Name: macB [H]

Synonym: Acid_2813

Alternate gene names: 116621928

Gene position: 3565078-3562664 (Counterclockwise)

Preceding gene: 116621931

Following gene: 116621926

Centisome position: 35.77

GC content: 66.25

Gene sequence:

>2415_bases
ATGAGCACCCTGATCTCAGATCTTCGCTATGGACTGCGACTGCTCCGTCACGCCCCGGGTTTTACCGCCGTCGCCATCGG
AGCGCTCGCCCTCGGCATCGGCGCTAATACCGCAATTTTTTCTACCGTGGACGCCGTGCTCCTGCGTCCCCTACCCTATG
CCGACCCCGACCGCGTGGTGGTGGTCTGGGAAGACGCCACCGCCGCGGGCTTCCCGCACAATACGCCGGCCTCCGGAAAC
TTCATCGAGTGGAAGAAGCGCAATCACGTCTTCACCGACATGGCCGCTACCCGCGGTTTTTCCGCAAACCTCACAGCCGA
CGGGGCCCCGGAGCAGGTGATCGGCCGCCGCGCCACCGCCAACTTCTTCCCCGTCCTGGGCGTGAACCCGATCGCCGGAC
GCATCTTCACCGAAGAGGAGGATCGCACCGGCGCGCCCGTAGTCGTGATCAGCTACGCCCTGTGGCAACGCCGCTACGCC
GGGTCGCCCGACGCCATCAATCGCGACATCCTGATCAACGGCCTCAAGTACTCCATTATCGGCATCATGCCGCGCGACTT
TTCGTTCCGCGATCGCGGCATGGATGTCTGGGTGCCCATTCACTTCTCCCCGAATGACCTGGTCACTCACAATTCGCATA
ACCTGAACGTGGCGGCGCGGCTCAAGCCCGGCGTGACCCTGGCCCGCGCACAGGAGGAGATGAGCGCTATCCAGCGCCAG
CTCAACGAGGAATTCCACGCGGATGCCATCAAGATCGGCGCTGCCGTGGTTCCGGCCCGCGAAGAAATGGTGGGAAACAC
GCGTTTGGAATTGCTGGTGCTGATGGGCGCCGCCGGCTGCGTCCTGCTGATCGCCTGCGCCAACCTCGCCGGCCTGCTGC
TGGCGCGCGGGGTCCGCCGCCGGCGCGAAATGGCGGTACGCTCCGCGCTCGGCGCCAGCCGTGCCCGCCTGGTGGCGCAG
ATGATGGCCGAAGGCACACTGATCGCGCTCGGCGGTGGAATCCTCGGGGTCGCGATGGCGCCGGTGGGCATGAAAGTCCT
CGCCACACTGGTGCCCACCGCGCTTCCCGCCAGCGCCGCGCCGGGCATCGATTTTCCGGTGCTCGCCTTTGCCTTTCTGC
TCTCCATTCTCACCGGCATCGGCTTCAGCATCGTGCCCGCATGGCAGGCCTCCCGCGTGTCCTTGAACGACGCGCTCAAG
CAGGGCGGCCGCGGCGGCATCGGCGGCGCCGGAGCCGGCACGCGTGATGCCCTCGTGGTGCTCGAAGTCGCCGCCGCGCT
GGTGCTGATGGTGAGCGCCGGACTCATGCTGCGGACCGTGGCCCGATTGCGCTCCGTCGAAATCGGTTTTCGCCCCGACC
ACCTGCTGACGTTGCGAACCACGCTCCCAGCGGGGAAATACCGGGAAGTTGATCGCCGCATCGCCTTCTACCATCGCGTG
TTGGATGGAGTGCGTGCGCTGCCCGGCGTACAGAATGCCGCCTACACCTCGAACGTCCCGTTCGCGAGCCCGGGCAATTC
CCAGATGTACGAGTTTGAAGGTCTGCCCCGCGTGCCGAGCGATCCCGGCGACGCCTTGCTGCGAGTCTCCAGCGGCGACT
ATCTGCAGACGTTGGGCGTGCGACCCATCGAAGGCCGCCTGCTCGACCACCGTGACGTCGAGCAGTCCGCCCCCGTGGCG
GTAATCAACGACACGCTCGCCAAGCTCTACTTCCCCAAGGGCGGCGCACTCGGCCATCGCATTCGCGTGAGCGCCCGCGT
GTTGACGTGGAGGACCATCGTCGGGGTGGTGAAGGACGTCCACGAACGCGGCTATGAACTTGCGATGAAGCCTGCCACGT
ACTATCCCTTCGAGCAGATGACGGATACGTGGGCGACGCCGGAAACACTGGTGGTGCGGACTACCAGCGATCCCGAAGGC
CTGGCCAGCGCGGTCCGCAAAGTGATTGCCTCCGTCGATCCCGAACAGCCCATCGCCGCCGTGCGCACCATGGACGACTT
CCTGGATAAAGATGTCGCCGATCGGCACCAGCAGATGACCCTGCTCACCGCCTTCGCCACGCTCGCGCTGCTGCTCGCAT
CGCTTGGCCTCTACAGCGTGCTGGCCTACACGGTGACTCAGCGCAGCCGCGAGATCGGGCTGCGTATGGCGCTCGGCGCC
AGCGCTTCGCGGGTTGTAAACATGGTGGTGCTACGCGGTATGATGCTGTCGGCCGCGGGACTGGTGCTGGGAATCGCTGC
GGCATGGACGCTGGCGCGAGCTATGAGCCGCCTGCTCTTCGGCGTTGCGCCGACCGACCCGGGGACCTACGCAGCCGTCG
CCGGACTGCTCGCCGTGATTGCCGCCGCGGCGTGTTGGATCCCCGCCCGCCGCGCCGTGAGAATCGACCCCATCACGGTG
CTGCGGGAGGAATAA

Upstream 100 bases:

>100_bases
AAGCGCAGATCCTGCGAGGTGGTGTCGATCATGTCTGTGTTACTCGCGACAACGGAAAAGGTTACGTAACCCTTTCCGCC
CGCGGCAGTATCTCCTCACA

Downstream 100 bases:

>100_bases
CGGAGCCGGTCAATCCAACGCACGCCGCAGGGCCTTCACGCCATCGGCGCACAATACCGCCGCGTGCTTAGACGCAGTCG
GCAGGCCGCCGACCGCTTCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 804; Mature: 803

Protein sequence:

>804_residues
MSTLISDLRYGLRLLRHAPGFTAVAIGALALGIGANTAIFSTVDAVLLRPLPYADPDRVVVVWEDATAAGFPHNTPASGN
FIEWKKRNHVFTDMAATRGFSANLTADGAPEQVIGRRATANFFPVLGVNPIAGRIFTEEEDRTGAPVVVISYALWQRRYA
GSPDAINRDILINGLKYSIIGIMPRDFSFRDRGMDVWVPIHFSPNDLVTHNSHNLNVAARLKPGVTLARAQEEMSAIQRQ
LNEEFHADAIKIGAAVVPAREEMVGNTRLELLVLMGAAGCVLLIACANLAGLLLARGVRRRREMAVRSALGASRARLVAQ
MMAEGTLIALGGGILGVAMAPVGMKVLATLVPTALPASAAPGIDFPVLAFAFLLSILTGIGFSIVPAWQASRVSLNDALK
QGGRGGIGGAGAGTRDALVVLEVAAALVLMVSAGLMLRTVARLRSVEIGFRPDHLLTLRTTLPAGKYREVDRRIAFYHRV
LDGVRALPGVQNAAYTSNVPFASPGNSQMYEFEGLPRVPSDPGDALLRVSSGDYLQTLGVRPIEGRLLDHRDVEQSAPVA
VINDTLAKLYFPKGGALGHRIRVSARVLTWRTIVGVVKDVHERGYELAMKPATYYPFEQMTDTWATPETLVVRTTSDPEG
LASAVRKVIASVDPEQPIAAVRTMDDFLDKDVADRHQQMTLLTAFATLALLLASLGLYSVLAYTVTQRSREIGLRMALGA
SASRVVNMVVLRGMMLSAAGLVLGIAAAWTLARAMSRLLFGVAPTDPGTYAAVAGLLAVIAAAACWIPARRAVRIDPITV
LREE

Sequences:

>Translated_804_residues
MSTLISDLRYGLRLLRHAPGFTAVAIGALALGIGANTAIFSTVDAVLLRPLPYADPDRVVVVWEDATAAGFPHNTPASGN
FIEWKKRNHVFTDMAATRGFSANLTADGAPEQVIGRRATANFFPVLGVNPIAGRIFTEEEDRTGAPVVVISYALWQRRYA
GSPDAINRDILINGLKYSIIGIMPRDFSFRDRGMDVWVPIHFSPNDLVTHNSHNLNVAARLKPGVTLARAQEEMSAIQRQ
LNEEFHADAIKIGAAVVPAREEMVGNTRLELLVLMGAAGCVLLIACANLAGLLLARGVRRRREMAVRSALGASRARLVAQ
MMAEGTLIALGGGILGVAMAPVGMKVLATLVPTALPASAAPGIDFPVLAFAFLLSILTGIGFSIVPAWQASRVSLNDALK
QGGRGGIGGAGAGTRDALVVLEVAAALVLMVSAGLMLRTVARLRSVEIGFRPDHLLTLRTTLPAGKYREVDRRIAFYHRV
LDGVRALPGVQNAAYTSNVPFASPGNSQMYEFEGLPRVPSDPGDALLRVSSGDYLQTLGVRPIEGRLLDHRDVEQSAPVA
VINDTLAKLYFPKGGALGHRIRVSARVLTWRTIVGVVKDVHERGYELAMKPATYYPFEQMTDTWATPETLVVRTTSDPEG
LASAVRKVIASVDPEQPIAAVRTMDDFLDKDVADRHQQMTLLTAFATLALLLASLGLYSVLAYTVTQRSREIGLRMALGA
SASRVVNMVVLRGMMLSAAGLVLGIAAAWTLARAMSRLLFGVAPTDPGTYAAVAGLLAVIAAAACWIPARRAVRIDPITV
LREE
>Mature_803_residues
STLISDLRYGLRLLRHAPGFTAVAIGALALGIGANTAIFSTVDAVLLRPLPYADPDRVVVVWEDATAAGFPHNTPASGNF
IEWKKRNHVFTDMAATRGFSANLTADGAPEQVIGRRATANFFPVLGVNPIAGRIFTEEEDRTGAPVVVISYALWQRRYAG
SPDAINRDILINGLKYSIIGIMPRDFSFRDRGMDVWVPIHFSPNDLVTHNSHNLNVAARLKPGVTLARAQEEMSAIQRQL
NEEFHADAIKIGAAVVPAREEMVGNTRLELLVLMGAAGCVLLIACANLAGLLLARGVRRRREMAVRSALGASRARLVAQM
MAEGTLIALGGGILGVAMAPVGMKVLATLVPTALPASAAPGIDFPVLAFAFLLSILTGIGFSIVPAWQASRVSLNDALKQ
GGRGGIGGAGAGTRDALVVLEVAAALVLMVSAGLMLRTVARLRSVEIGFRPDHLLTLRTTLPAGKYREVDRRIAFYHRVL
DGVRALPGVQNAAYTSNVPFASPGNSQMYEFEGLPRVPSDPGDALLRVSSGDYLQTLGVRPIEGRLLDHRDVEQSAPVAV
INDTLAKLYFPKGGALGHRIRVSARVLTWRTIVGVVKDVHERGYELAMKPATYYPFEQMTDTWATPETLVVRTTSDPEGL
ASAVRKVIASVDPEQPIAAVRTMDDFLDKDVADRHQQMTLLTAFATLALLLASLGLYSVLAYTVTQRSREIGLRMALGAS
ASRVVNMVVLRGMMLSAAGLVLGIAAAWTLARAMSRLLFGVAPTDPGTYAAVAGLLAVIAAAACWIPARRAVRIDPITVL
REE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=293, Percent_Identity=24.2320819112628, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 86089; Mature: 85958

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLISDLRYGLRLLRHAPGFTAVAIGALALGIGANTAIFSTVDAVLLRPLPYADPDRVV
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCEE
VVWEDATAAGFPHNTPASGNFIEWKKRNHVFTDMAATRGFSANLTADGAPEQVIGRRATA
EEECCCCCCCCCCCCCCCCCEEEECCCCCEEHHHHHHCCCCCCCCCCCCCHHHHCCCCCC
NFFPVLGVNPIAGRIFTEEEDRTGAPVVVISYALWQRRYAGSPDAINRDILINGLKYSII
CCCCCCCCCCCCCCEEECCCCCCCCCEEEEHHHHHHHHCCCCCCCCCCCEEEECCEEEEE
GIMPRDFSFRDRGMDVWVPIHFSPNDLVTHNSHNLNVAARLKPGVTLARAQEEMSAIQRQ
EECCCCCCCCCCCCEEEEEEEECCCCCEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHH
LNEEFHADAIKIGAAVVPAREEMVGNTRLELLVLMGAAGCVLLIACANLAGLLLARGVRR
HHHHHHHHHHHHCHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RREMAVRSALGASRARLVAQMMAEGTLIALGGGILGVAMAPVGMKVLATLVPTALPASAA
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
PGIDFPVLAFAFLLSILTGIGFSIVPAWQASRVSLNDALKQGGRGGIGGAGAGTRDALVV
CCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHH
LEVAAALVLMVSAGLMLRTVARLRSVEIGFRPDHLLTLRTTLPAGKYREVDRRIAFYHRV
HHHHHHHHHHHHCCHHHHHHHHHHHEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
LDGVRALPGVQNAAYTSNVPFASPGNSQMYEFEGLPRVPSDPGDALLRVSSGDYLQTLGV
HHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEEECCCCHHHHCCC
RPIEGRLLDHRDVEQSAPVAVINDTLAKLYFPKGGALGHRIRVSARVLTWRTIVGVVKDV
CCCCCCCCCCCCCHHCCCEEEEEHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
HERGYELAMKPATYYPFEQMTDTWATPETLVVRTTSDPEGLASAVRKVIASVDPEQPIAA
HHCCCEEEECCCCCCCHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHH
VRTMDDFLDKDVADRHQQMTLLTAFATLALLLASLGLYSVLAYTVTQRSREIGLRMALGA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCC
SASRVVNMVVLRGMMLSAAGLVLGIAAAWTLARAMSRLLFGVAPTDPGTYAAVAGLLAVI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
AAAACWIPARRAVRIDPITVLREE
HHHHHHHCCCCEEEECCEEEEECC
>Mature Secondary Structure 
STLISDLRYGLRLLRHAPGFTAVAIGALALGIGANTAIFSTVDAVLLRPLPYADPDRVV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCEE
VVWEDATAAGFPHNTPASGNFIEWKKRNHVFTDMAATRGFSANLTADGAPEQVIGRRATA
EEECCCCCCCCCCCCCCCCCEEEECCCCCEEHHHHHHCCCCCCCCCCCCCHHHHCCCCCC
NFFPVLGVNPIAGRIFTEEEDRTGAPVVVISYALWQRRYAGSPDAINRDILINGLKYSII
CCCCCCCCCCCCCCEEECCCCCCCCCEEEEHHHHHHHHCCCCCCCCCCCEEEECCEEEEE
GIMPRDFSFRDRGMDVWVPIHFSPNDLVTHNSHNLNVAARLKPGVTLARAQEEMSAIQRQ
EECCCCCCCCCCCCEEEEEEEECCCCCEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHH
LNEEFHADAIKIGAAVVPAREEMVGNTRLELLVLMGAAGCVLLIACANLAGLLLARGVRR
HHHHHHHHHHHHCHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RREMAVRSALGASRARLVAQMMAEGTLIALGGGILGVAMAPVGMKVLATLVPTALPASAA
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
PGIDFPVLAFAFLLSILTGIGFSIVPAWQASRVSLNDALKQGGRGGIGGAGAGTRDALVV
CCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHH
LEVAAALVLMVSAGLMLRTVARLRSVEIGFRPDHLLTLRTTLPAGKYREVDRRIAFYHRV
HHHHHHHHHHHHCCHHHHHHHHHHHEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
LDGVRALPGVQNAAYTSNVPFASPGNSQMYEFEGLPRVPSDPGDALLRVSSGDYLQTLGV
HHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEEECCCCHHHHCCC
RPIEGRLLDHRDVEQSAPVAVINDTLAKLYFPKGGALGHRIRVSARVLTWRTIVGVVKDV
CCCCCCCCCCCCCHHCCCEEEEEHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
HERGYELAMKPATYYPFEQMTDTWATPETLVVRTTSDPEGLASAVRKVIASVDPEQPIAA
HHCCCEEEECCCCCCCHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHH
VRTMDDFLDKDVADRHQQMTLLTAFATLALLLASLGLYSVLAYTVTQRSREIGLRMALGA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCC
SASRVVNMVVLRGMMLSAAGLVLGIAAAWTLARAMSRLLFGVAPTDPGTYAAVAGLLAVI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
AAAACWIPARRAVRIDPITVLREE
HHHHHHHCCCCEEEECCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA