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The map label for this gene is 116621881

Identifier: 116621881

GI number: 116621881

Start: 3504072

End: 3505265

Strand: Reverse

Name: 116621881

Synonym: Acid_2764

Alternate gene names: NA

Gene position: 3505265-3504072 (Counterclockwise)

Preceding gene: 116621882

Following gene: 116621880

Centisome position: 35.17

GC content: 63.99

Gene sequence:

>1194_bases
TTGAAGCGCCTACTCGTTATGGGGCTGCTCGCGGGGGCAGCGTTCGCCCGACAGCCGCTGCTGGTGATCTCGGTGGACGG
ACTTGACCAGCGCTACCTTGCACACTGCGACGAGATGAAGCTGAAGATTCCGAACCTGCGGCGGTTGATGCGGGAGGGCC
AATGGTCGCGCGGCGTGATCGGCGTGATGCCTACAATCACGTGGCCTTCGCACACCACGATTCTGACGGGCGTGGATCCC
AAGGTACACGGCGTCCTGAGCAATCGGAAACCAGCCGCGGAAGGGGGAGATTATCCGTGGAGCGCGAAGCTCCTGAAAGC
ACGGACGCTGCTGGACGCGGCTCATGAGGCGGGATTGAAAACGGCCGCGATTACGTGGCCGGTGACGGTGGATGCGCCGG
CCAGTTTCAATCTGCCGGAGTACTTCCAACGCCGCCGAGGGGGCGCGATGGACCTGCGCTCGATCGAGAGCAAAGCGGTT
CCGGCCGACCTGGTGACGCGGATCGCGGGCATGTTCCCATCGTTCGCGCAGGAGTGGATGGACGATCGGACGCGCACACA
GGCAGTGGTCTCCCTGCTGCGAGCGGAGCGACCCGACCTGCTGGTGGTACACCTGGTCGATCTGGATTCCGAGGAGCATG
ATAACGCGCCGTTCTCCCGCGAATCCAATGCAATACTCGAATATACCGATGAACTGATCGGCCGCATGTTGGAGGCACTG
GCGCCGGGCTCCGCGGTGGCGCTGGTCTCCGACCACGGCTTCGAGAAGGTGGAGATGGAGGTAAACCTGGCGGCGTTCGC
AGCGGAGGCGGGTGTCGCAGGGGTGCGCCCGATGGGCTCGATCGCGGTCGCGGAAACCGAGCCATCGGCCGAGTTTGTGC
GCACCACGAGCCGGGACCCGCGGTACGGGATCGGGCGGGTGATCCCAAAGGATGAGGTCGCGCGCTTCGCTCCGCAGTTC
GAAAGCGCCGCCGCGGTGTTTGAGTCCGCTCCGGGATTCCTGTTCGCATCCGGCAATTCCGGGGAGGTGTTCAGCAAACC
GCGCGAAACCGGCAACCACGGGCATTGGCCTATGCGGTATCGCTCCGTTTACGTGCTGTGGGGCGCAGGTATCGCACCGG
CGAACCTGCCCGAGTTCTCACTCAAGGAAATTGCAGGCAAGCTCGCGGCGGTAATCGATGTGAGAATGCCGTAG

Upstream 100 bases:

>100_bases
GCTCCGGCGCGGTGGTGAGCACGTTCAACGCTCCGGACTTTCTGCGGATTACGTCAACTTTCAATTCGCGCCAGATTCAG
CTGGGCGGGAGGCTACGGTT

Downstream 100 bases:

>100_bases
CGACCGGGCAAGCGAAGCCGCGAGAAGTTCGGAACAGGCAGGCTGAAACATGTCCCCGACACTGCAAAACATCGCCCCAG
TGGAGCATATTTTAACTTTG

Product: type I phosphodiesterase/nucleotide pyrophosphatase

Products: NA

Alternate protein names: Nucleotide Pyrophosphatase; Pyrophosphatase; Phosphoglyceromutase/Phosphopentomutase; AP Endonuclease; Phosphodiesterase/Nucleotide Pyrophosphatase Family Protein; Hydrolase

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MKRLLVMGLLAGAAFARQPLLVISVDGLDQRYLAHCDEMKLKIPNLRRLMREGQWSRGVIGVMPTITWPSHTTILTGVDP
KVHGVLSNRKPAAEGGDYPWSAKLLKARTLLDAAHEAGLKTAAITWPVTVDAPASFNLPEYFQRRRGGAMDLRSIESKAV
PADLVTRIAGMFPSFAQEWMDDRTRTQAVVSLLRAERPDLLVVHLVDLDSEEHDNAPFSRESNAILEYTDELIGRMLEAL
APGSAVALVSDHGFEKVEMEVNLAAFAAEAGVAGVRPMGSIAVAETEPSAEFVRTTSRDPRYGIGRVIPKDEVARFAPQF
ESAAAVFESAPGFLFASGNSGEVFSKPRETGNHGHWPMRYRSVYVLWGAGIAPANLPEFSLKEIAGKLAAVIDVRMP

Sequences:

>Translated_397_residues
MKRLLVMGLLAGAAFARQPLLVISVDGLDQRYLAHCDEMKLKIPNLRRLMREGQWSRGVIGVMPTITWPSHTTILTGVDP
KVHGVLSNRKPAAEGGDYPWSAKLLKARTLLDAAHEAGLKTAAITWPVTVDAPASFNLPEYFQRRRGGAMDLRSIESKAV
PADLVTRIAGMFPSFAQEWMDDRTRTQAVVSLLRAERPDLLVVHLVDLDSEEHDNAPFSRESNAILEYTDELIGRMLEAL
APGSAVALVSDHGFEKVEMEVNLAAFAAEAGVAGVRPMGSIAVAETEPSAEFVRTTSRDPRYGIGRVIPKDEVARFAPQF
ESAAAVFESAPGFLFASGNSGEVFSKPRETGNHGHWPMRYRSVYVLWGAGIAPANLPEFSLKEIAGKLAAVIDVRMP
>Mature_397_residues
MKRLLVMGLLAGAAFARQPLLVISVDGLDQRYLAHCDEMKLKIPNLRRLMREGQWSRGVIGVMPTITWPSHTTILTGVDP
KVHGVLSNRKPAAEGGDYPWSAKLLKARTLLDAAHEAGLKTAAITWPVTVDAPASFNLPEYFQRRRGGAMDLRSIESKAV
PADLVTRIAGMFPSFAQEWMDDRTRTQAVVSLLRAERPDLLVVHLVDLDSEEHDNAPFSRESNAILEYTDELIGRMLEAL
APGSAVALVSDHGFEKVEMEVNLAAFAAEAGVAGVRPMGSIAVAETEPSAEFVRTTSRDPRYGIGRVIPKDEVARFAPQF
ESAAAVFESAPGFLFASGNSGEVFSKPRETGNHGHWPMRYRSVYVLWGAGIAPANLPEFSLKEIAGKLAAVIDVRMP

Specific function: Unknown

COG id: COG1524

COG function: function code R; Uncharacterized proteins of the AP superfamily

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI170650661, Length=256, Percent_Identity=24.21875, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI111160296, Length=256, Percent_Identity=24.21875, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 43322; Mature: 43322

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLLVMGLLAGAAFARQPLLVISVDGLDQRYLAHCDEMKLKIPNLRRLMREGQWSRGVI
CCHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHEEECHHHHHHHHCCCCCCCEE
GVMPTITWPSHTTILTGVDPKVHGVLSNRKPAAEGGDYPWSAKLLKARTLLDAAHEAGLK
EEECEECCCCCCEEEECCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
TAAITWPVTVDAPASFNLPEYFQRRRGGAMDLRSIESKAVPADLVTRIAGMFPSFAQEWM
EEEEEEEEEECCCCCCCCHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHCHHHHHHHH
DDRTRTQAVVSLLRAERPDLLVVHLVDLDSEEHDNAPFSRESNAILEYTDELIGRMLEAL
HHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
APGSAVALVSDHGFEKVEMEVNLAAFAAEAGVAGVRPMGSIAVAETEPSAEFVRTTSRDP
CCCCEEEEEECCCCEEEEEEEEHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHCCCCCC
RYGIGRVIPKDEVARFAPQFESAAAVFESAPGFLFASGNSGEVFSKPRETGNHGHWPMRY
CCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEE
RSVYVLWGAGIAPANLPEFSLKEIAGKLAAVIDVRMP
EEEEEEEECCCCCCCCCCHHHHHHHHHHHHHEEECCC
>Mature Secondary Structure
MKRLLVMGLLAGAAFARQPLLVISVDGLDQRYLAHCDEMKLKIPNLRRLMREGQWSRGVI
CCHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHEEECHHHHHHHHCCCCCCCEE
GVMPTITWPSHTTILTGVDPKVHGVLSNRKPAAEGGDYPWSAKLLKARTLLDAAHEAGLK
EEECEECCCCCCEEEECCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
TAAITWPVTVDAPASFNLPEYFQRRRGGAMDLRSIESKAVPADLVTRIAGMFPSFAQEWM
EEEEEEEEEECCCCCCCCHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHCHHHHHHHH
DDRTRTQAVVSLLRAERPDLLVVHLVDLDSEEHDNAPFSRESNAILEYTDELIGRMLEAL
HHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
APGSAVALVSDHGFEKVEMEVNLAAFAAEAGVAGVRPMGSIAVAETEPSAEFVRTTSRDP
CCCCEEEEEECCCCEEEEEEEEHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHCCCCCC
RYGIGRVIPKDEVARFAPQFESAAAVFESAPGFLFASGNSGEVFSKPRETGNHGHWPMRY
CCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEE
RSVYVLWGAGIAPANLPEFSLKEIAGKLAAVIDVRMP
EEEEEEEECCCCCCCCCCHHHHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA