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The map label for this gene is scrA [H]

Identifier: 116517116

GI number: 116517116

Start: 1554035

End: 1555918

Strand: Reverse

Name: scrA [H]

Synonym: SPD_1532

Alternate gene names: 116517116

Gene position: 1555918-1554035 (Counterclockwise)

Preceding gene: 116515797

Following gene: 116516735

Centisome position: 76.04

GC content: 44.06

Gene sequence:

>1884_bases
ATGAACAATCAGGAAATTGCAAAAAAAGTCATCGATGCCTTGGGCGGACGTGAAAATGTCAATAGTGTTGCCCACTGTGC
GACTCGTCTACGTGTCATGGTCAAAGATGAAGAGAAAATCAATAAAGAAGTGATTGAGAACTTGGAAAAAGTTCAAGGTG
CTTTCTTTAACTCAGGGCAATACCAAATTATCTTTGGTACAGGTACAGTTAACAAAATGTACGATGAAGTTGTTGTACTT
GGCTTACCAACATCATCTAAGGATGACATGAAAGCAGAAGTTGCTAAACAAGGGAACTGGTTCCAACGTGCTATCCGTAC
TTTCGGTGATGTTTTCGTTCCAATCATCCCAGTTATCGTAGCGACAGGTCTCTTCATGGGTGTGCGTGGTCTTTTCAACG
CTCTTGAAATGCCACTTCCAGGTGACTTTGCAACTTACACACAAATCTTGACAGATACAGCCTTCATCATCTTGCCAGGT
TTGGTTGTGTGGTCAACCTTCCGTGTATTTGGTGGAAATCCTGCCGTTGGTATCGTTCTTGGTATGATGCTTGTCTCTGG
CTCACTTCCAAACGCTTGGGCAGTTGCTCAAGGTGGTGAAGTAACAGCGATGAACTTCTTTGGTTTCATCCCTGTTGTTG
GTTTGCAAGGTTCCGTTCTTCCAGCCTTCATCATCGGGGTTGTCGGAGCTAAATTTGAAAAAGCTGTCCGCAAGGTTGTT
CCAGATGTCATTGACCTCTTGGTAACACCATTCGTGACACTTTTGGTCATGTCTATCCTTGGACTCTTTGTCATTGGACC
AGTTTTCCACGTTGTTGAAAACTACATCCTTATTGCTACAAAAGCGATTCTTAGCATGCCATTTGGTCTTGGTGGTTTCT
TGATTGGTGGGGTTCACCAATTGATCGTCGTGTCAGGTGTGCACCACATCTTCAACTTGCTTGAAGTGCAATTACTTGCT
GCTGACCATGCTAACCCATTCAACGCTATCATCACAGCTGCTATGACAGCTCAAGGTGCTGCTACTGTTGCGGTTGGTGT
TAAAACAAAAAATCCAAAACTGAAAACACTTGCTTTCCCGGCTGCTCTTTCTGCCTTCCTAGGTATTACAGAGCCTGCTA
TCTTCGGGGTGAACTTGCGCTTCCGTAAACCATTCTTCCTTTCATTGATTGCTGGTGCAATCGGTGGTGGATTGGCTTCT
ATCCTTGGACTTGCTGGTACTGGTAATGGTATCACCATCATCCCTGGTACAATGCTTTATGTTGGTAACGGACAACTTCC
ACAATACCTTCTTATGGTAGCTGTATCATTTGCCCTTGGTTTTGCTCTTACTTACATGTTTGGTTACGAAGATGAAGTAG
ACGCAACTGCAGCTGCAAAACAAGCTGAAGTGGCTGAAGAAAAAGAAGAAGTTGCGCCAGCAGCTCTTCAAAATGAAACA
CTTGTAACTCCTATCGTCGGTGATGTTGTCGCTCTTGCTGATGTCAATGACCCAGTCTTCTCAAGTGGAGCTATGGGACA
AGGTATCGCTGTGAAACCAAGTCAAGGCGTGGTCTATGCACTAGCTGATGCTGAAGTTTCAATTGCCTTTCCAACAGGGC
ACGCTTTTGGTTTGAAAACAAGAAATGGTGCTGAAGTTTTGATTCACGTTGGTATTGACACTGTATCTATGAACGGTGAC
GGTTTTGAAGCAAAAGTTGCTCAAGGTAATAAGGTGAAAGCTGGCGATGTTCTTGGAACATTTGACTCAAACAAAATCGC
TGCAGCTGGACTTGATGATACAACAATGGTTATCGTTACAAATACAGCTGACTACGCTTCAGTAGCTCCAGTCGCAACAG
GTTCAGTTTCGAAGGGGGATGCTGTGATCGAAGTGAAAATCTAA

Upstream 100 bases:

>100_bases
CGCTTGACATATTTTTAAAACATGATAAAATAATAGTCGTAAGGGCGAATAAAATCGCTTTCAAACAAGAACAAAATGTT
ATATAAGGAGATTTTTGCAA

Downstream 100 bases:

>100_bases
TCAATCCTCTCTAATGTGAAAACGAACAAATGACATGTTTGTTCGTTTTTATTAGATAGTAAGATTTACAGAGGAAAATC
TAAAAAATAGAGACATTTAG

Product: PTS system IIABC components

Products: NA

Alternate protein names: EIIBCA-Scr; EII-Scr; Sucrose-specific phosphotransferase enzyme IIB component; PTS system sucrose-specific EIIB component; Sucrose permease IIC component; PTS system sucrose-specific EIIC component; Sucrose-specific phosphotransferase enzyme IIA component; PTS system sucrose-specific EIIA component [H]

Number of amino acids: Translated: 627; Mature: 627

Protein sequence:

>627_residues
MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEVIENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVL
GLPTSSKDDMKAEVAKQGNWFQRAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGSVLPAFIIGVVGAKFEKAVRKVV
PDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYILIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLA
ADHANPFNAIITAAMTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAGAIGGGLAS
ILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYEDEVDATAAAKQAEVAEEKEEVAPAALQNET
LVTPIVGDVVALADVNDPVFSSGAMGQGIAVKPSQGVVYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGD
GFEAKVAQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVSKGDAVIEVKI

Sequences:

>Translated_627_residues
MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEVIENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVL
GLPTSSKDDMKAEVAKQGNWFQRAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGSVLPAFIIGVVGAKFEKAVRKVV
PDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYILIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLA
ADHANPFNAIITAAMTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAGAIGGGLAS
ILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYEDEVDATAAAKQAEVAEEKEEVAPAALQNET
LVTPIVGDVVALADVNDPVFSSGAMGQGIAVKPSQGVVYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGD
GFEAKVAQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVSKGDAVIEVKI
>Mature_627_residues
MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEVIENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVL
GLPTSSKDDMKAEVAKQGNWFQRAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGSVLPAFIIGVVGAKFEKAVRKVV
PDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYILIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLA
ADHANPFNAIITAAMTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAGAIGGGLAS
ILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYEDEVDATAAAKQAEVAEEKEEVAPAALQNET
LVTPIVGDVVALADVNDPVFSSGAMGQGIAVKPSQGVVYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGD
GFEAKVAQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVSKGDAVIEVKI

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1790159, Length=635, Percent_Identity=29.6062992125984, Blast_Score=252, Evalue=4e-68,
Organism=Escherichia coli, GI2367362, Length=428, Percent_Identity=29.2056074766355, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI48994906, Length=506, Percent_Identity=29.8418972332016, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1788769, Length=476, Percent_Identity=26.890756302521, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1786894, Length=160, Percent_Identity=37.5, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1788757, Length=147, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR010973 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 65644; Mature: 65644

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEVIENLEKVQGAFFNSGQ
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHCCCCC
YQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQRAIRTFGDVFVPIIPVIV
EEEEEECCCHHHHCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPGLVVWSTFRVFGGNPAVGIVL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
GMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGSVLPAFIIGVVGAKFEKAVRKVV
HHHHHCCCCCCCEEEECCCCEEEEEHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
PDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYILIATKAILSMPFGLGGFLIGGVHQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LIVVSGVHHIFNLLEVQLLAADHANPFNAIITAAMTAQGAATVAVGVKTKNPKLKTLAFP
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEHH
AALSAFLGITEPAIFGVNLRFRKPFFLSLIAGAIGGGLASILGLAGTGNGITIIPGTMLY
HHHHHHHCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEE
VGNGQLPQYLLMVAVSFALGFALTYMFGYEDEVDATAAAKQAEVAEEKEEVAPAALQNET
ECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCE
LVTPIVGDVVALADVNDPVFSSGAMGQGIAVKPSQGVVYALADAEVSIAFPTGHAFGLKT
EECHHHHCEEEEECCCCCCCCCCCCCCCEEECCCCCEEEEEECCEEEEEECCCCEEECCC
RNGAEVLIHVGIDTVSMNGDGFEAKVAQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVT
CCCCEEEEEECCEEEEECCCCCEEEECCCCEEECCCEEEECCCCCEEEECCCCCEEEEEE
NTADYASVAPVATGSVSKGDAVIEVKI
CCCCCCCCCCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEVIENLEKVQGAFFNSGQ
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHCCCCC
YQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQRAIRTFGDVFVPIIPVIV
EEEEEECCCHHHHCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPGLVVWSTFRVFGGNPAVGIVL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
GMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGSVLPAFIIGVVGAKFEKAVRKVV
HHHHHCCCCCCCEEEECCCCEEEEEHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
PDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYILIATKAILSMPFGLGGFLIGGVHQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LIVVSGVHHIFNLLEVQLLAADHANPFNAIITAAMTAQGAATVAVGVKTKNPKLKTLAFP
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEHH
AALSAFLGITEPAIFGVNLRFRKPFFLSLIAGAIGGGLASILGLAGTGNGITIIPGTMLY
HHHHHHHCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEE
VGNGQLPQYLLMVAVSFALGFALTYMFGYEDEVDATAAAKQAEVAEEKEEVAPAALQNET
ECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCE
LVTPIVGDVVALADVNDPVFSSGAMGQGIAVKPSQGVVYALADAEVSIAFPTGHAFGLKT
EECHHHHCEEEEECCCCCCCCCCCCCCCEEECCCCCEEEEEECCEEEEEECCCCEEECCC
RNGAEVLIHVGIDTVSMNGDGFEAKVAQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVT
CCCCEEEEEECCEEEEECCCCCEEEECCCCEEECCCEEEECCCCCEEEECCCCCEEEEEE
NTADYASVAPVATGSVSKGDAVIEVKI
CCCCCCCCCCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2536656; 12397186; 8336109 [H]