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The map label for this gene is xylR [H]

Identifier: 116517006

GI number: 116517006

Start: 424598

End: 425821

Strand: Reverse

Name: xylR [H]

Synonym: SPD_0423

Alternate gene names: 116517006

Gene position: 425821-424598 (Counterclockwise)

Preceding gene: 116517119

Following gene: 116515513

Centisome position: 20.81

GC content: 33.82

Gene sequence:

>1224_bases
ATGATTACAAAACAATCAGCCTTTTTACAAAATAGAGCCACTATACTGGAGTTTCTATATCGAAATCCAGCAACATCCCG
TACAGATATTGTTAATGAAACAGGACTTACTCCAGCAACAACGACTAACATCATAAAAGAGCTAAGCGAACAGTCCCTCA
TATACGAAACTGGTGATGAATTTAGCGAGTTTTCCGGATCTGGAAGACGTAGAAAAACTATTTCTATCACAGATAATATT
CCGTATGTTGTTGGAGGTATTGAAATAAACGTCCTAGGTATCTTTCTCAGTCTATGTGACTTACAAGGGAAAACTCTTTT
CGAGACAGAAATTTTGAATGAAGATTATCCTATTTCAGAAATCAATTCCACCATTACCAATATGATAAAAACAGCTATAG
AGTACGTCCCTTTGGAAACAAAATTACTTGGATTTGGCTTATCAATACCTGGACATTATAACAAAGACTCCGGAAGTATC
ATTACAAACAACCCCATATGGGAATCTTTTAATTTATTAAATGTAATTAAAGATTTCAATTTTCCTTTTATTGTAAAAAA
TAATATCGATTGTATGGCTATAGGACAATACCTTTTTAATCCACACAATACCCCCGATAACTTTATTTTCCTACACGCTG
GATTAGGTATTTACACTTCCTTTTTCACAAAAGAAAAAATAGGAGCCTCTAAAAATCCTTATATCGGAGAAATTGGACAC
ACCATTGTCGAATTGAATGGGCAATATTGTGAATGCGGAAAAAAAGGTTGTTTACAAACATATATTTCGGATGCTTGGTT
AATCAAACACGCCCAATTATTATTTAAAAATTCCCAACTAACTGTACTAAAAAGCCTTGTAAAGACTGAAAAAGACATTC
ATTTAGACACCCTTTTAACGGCTTATAATTTAGGCGACTCCGCTTTACGTCAACAAATTGATAAAGGAGTCAATTTATTA
GCCACTTCTATTGCAAATCTCCTCCTCATCAATCCTGCTGATAAAATCTATATCAACAGTCAATTGCTTAATTATCAACC
TTTCACTCATGAAGTCAGGGATAAAATCCAAGACCAGCTCCACTTCGTTCCCTTTACTCGTAATATAGAAATTGAAATTT
TACCTTACAACAAACATCGTGGAAGTATAGGAGCTTGTGCATTAGCTATCGTCGCTTTTTTCATAGAACATAGCAATGTA
TTACAAGATATTATTTCACCTTAA

Upstream 100 bases:

>100_bases
TTTTTTGTTGTTTTTACAATATTTTTTTCTTTGTATAGAATAATAATTTTAATTGATTTTTTCTTATGTTTAATATAAAA
TAAACCAAAGGAGGAAACAA

Downstream 100 bases:

>100_bases
TATATTAGAAATCTATAGACCTGTTTAAATCAACTATAACCTGTAGTAGATATCTCGTATTTAGACAATATGAAAACAAG
ACGACTTCCATATAGGAAAC

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNIIKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNI
PYVVGGIEINVLGIFLSLCDLQGKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
ITNNPIWESFNLLNVIKDFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIYTSFFTKEKIGASKNPYIGEIGH
TIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFKNSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLL
ATSIANLLLINPADKIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVAFFIEHSNV
LQDIISP

Sequences:

>Translated_407_residues
MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNIIKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNI
PYVVGGIEINVLGIFLSLCDLQGKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
ITNNPIWESFNLLNVIKDFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIYTSFFTKEKIGASKNPYIGEIGH
TIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFKNSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLL
ATSIANLLLINPADKIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVAFFIEHSNV
LQDIISP
>Mature_407_residues
MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNIIKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNI
PYVVGGIEINVLGIFLSLCDLQGKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
ITNNPIWESFNLLNVIKDFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIYTSFFTKEKIGASKNPYIGEIGH
TIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFKNSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLL
ATSIANLLLINPADKIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVAFFIEHSNV
LQDIISP

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=289, Percent_Identity=24.2214532871972, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI298566315, Length=289, Percent_Identity=24.2214532871972, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI4885285, Length=289, Percent_Identity=24.2214532871972, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI190014632, Length=289, Percent_Identity=24.2214532871972, Blast_Score=83, Evalue=6e-16,
Organism=Escherichia coli, GI1786891, Length=393, Percent_Identity=25.6997455470738, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787878, Length=395, Percent_Identity=23.7974683544304, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI87082127, Length=375, Percent_Identity=23.4666666666667, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 45695; Mature: 45695

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNIIKELSEQSLIYETGDE
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCEEECCCCH
FSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQGKTLFETEILNEDYPISE
HHHHCCCCCCEEEEEEECCCCEEEECEEEEHHHHHHHHHHCCCCEEEHHHHCCCCCCHHH
INSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSIITNNPIWESFNLLNVIKDFN
HHHHHHHHHHHHHHHCCCHHHEEEECCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCC
FPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIYTSFFTKEKIGASKNPYIGEIGH
CCEEEECCCCEEEEHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHHCCCCCCCCCHHCCC
TIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFKNSQLTVLKSLVKTEKDIHLDTLLT
EEEEECCCHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHH
AYNLGDSALRQQIDKGVNLLATSIANLLLINPADKIYINSQLLNYQPFTHEVRDKIQDQL
HHCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEECCEEECCCCCHHHHHHHHHHCE
HFVPFTRNIEIEILPYNKHRGSIGACALAIVAFFIEHSNVLQDIISP
EEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNIIKELSEQSLIYETGDE
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCEEECCCCH
FSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQGKTLFETEILNEDYPISE
HHHHCCCCCCEEEEEEECCCCEEEECEEEEHHHHHHHHHHCCCCEEEHHHHCCCCCCHHH
INSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSIITNNPIWESFNLLNVIKDFN
HHHHHHHHHHHHHHHCCCHHHEEEECCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCC
FPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIYTSFFTKEKIGASKNPYIGEIGH
CCEEEECCCCEEEEHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHHCCCCCCCCCHHCCC
TIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFKNSQLTVLKSLVKTEKDIHLDTLLT
EEEEECCCHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHH
AYNLGDSALRQQIDKGVNLLATSIANLLLINPADKIYINSQLLNYQPFTHEVRDKIQDQL
HHCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEECCEEECCCCCHHHHHHHHHHCE
HFVPFTRNIEIEILPYNKHRGSIGACALAIVAFFIEHSNVLQDIISP
EEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]