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The map label for this gene is aroB

Identifier: 116516860

GI number: 116516860

Start: 1237878

End: 1238945

Strand: Reverse

Name: aroB

Synonym: SPD_1209

Alternate gene names: 116516860

Gene position: 1238945-1237878 (Counterclockwise)

Preceding gene: 116516036

Following gene: 116516017

Centisome position: 60.55

GC content: 44.94

Gene sequence:

>1068_bases
ATGAAAATCAGAATCGATATTCCTCATCATCCTTATGATATTCAGATTGAAAAAGGTTGTATGGCCCAGGCTGGTCAGTG
GTTGCGAGAACTCTGGCAACCGCAAAAGGTAGTCATTGTGACAGATAACCATGTAGCCTCTCTCTATGCAGAGAAGGTCA
AGCTCAGCCTAGAAGATGCTGGTTTTCAGGTAGCTGTTTTTGATTTCTTAGAAGGTGAAGAAAGAAAGAATTTAACTACT
GTTCAGAAAGTCTATGAATTTCTAGTCAAGCAAGGTCTGACTCGTAGCGATGGAATCGTTGCTCTTGGTGGTGGCGTTGT
TGGGGACCTGGCTGGCTTTGTAGCCTCTACCTATATGCGGGGTATTCACTTTGTTCAGATTCCGACTAGTTTGACAGCTC
AGGTTGATTCTTCTATCGGTGGAAAGACAGGCGTTAACACACCATTTGCTAAAAATATGGTGGGGACCTTTGCCCAACCA
GATGGGGTTCTGATTGATCCACTTGTTCTTGAAACCCTCGGAAAAAGAGAGTTGATTGAAGGGATGGGTGAAGTTATCAA
GTATGGCTTGATTGAGGATCCAGAACTGTGGGCTCTCTTGACGGGGCTGAATGGTTCTGTTGAGAGCATTTTGGAACATG
CAGAGACCTTGATTGAACATTCTTGTCAGGTGAAGCGCAAGATGGTGGTTGAAGATGAGTTGGACAATGGTATTCGTCTT
TACCTCAATTTTGGCCACACTATTGGCCATGCCATCGAAGCGACTGCCGGTTATGGCAAGGTCATGCATGGAGAGGCTGT
TGCCATGGGAATGGTACAGATTTCCAAGATTGCTGAGGAAAAAGGCCTCATGCCAGCTGGCATTACCCAATCTATCACAG
AGATGTGTCAGAAATTCGGCTTGCCTGTTGACTATGAAAATTGGGAAGTTGACAAGCTTTATCAGGCTCTTACTCATGAC
AAGAAAGCGCGTGGCAACACCTTGAAATTGGTCTTGGTGCCAGAGCTTGGTTCAGCGACCATTCATCCAGTTTCTCTGGA
AGAGATGAAAGACTACTTGGTAAAATAA

Upstream 100 bases:

>100_bases
TGCAGAAGCTTTTCAACTGTGGACAGGCAAGGAAATGCCGACAGAAGAGATTTGGCAGTCTTTAACAGAAAAATACCAAT
AAAGAAAGGGAGACTCTCCT

Downstream 100 bases:

>100_bases
GGAGAGTGTATGAGATATTTAACTGCAGGAGAATCACACGGCCCCCGTCTAACAGCTATTATTGAGGGAATTCCAGCTGG
ACTTCCATTGACAGCTGAGG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNHVASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTT
VQKVYEFLVKQGLTRSDGIVALGGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLIEHSCQVKRKMVVEDELDNGIRL
YLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISKIAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHD
KKARGNTLKLVLVPELGSATIHPVSLEEMKDYLVK

Sequences:

>Translated_355_residues
MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNHVASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTT
VQKVYEFLVKQGLTRSDGIVALGGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLIEHSCQVKRKMVVEDELDNGIRL
YLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISKIAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHD
KKARGNTLKLVLVPELGSATIHPVSLEEMKDYLVK
>Mature_355_residues
MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNHVASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTT
VQKVYEFLVKQGLTRSDGIVALGGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLIEHSCQVKRKMVVEDELDNGIRL
YLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISKIAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHD
KKARGNTLKLVLVPELGSATIHPVSLEEMKDYLVK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=346, Percent_Identity=39.0173410404624, Blast_Score=226, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6320332, Length=345, Percent_Identity=35.0724637681159, Blast_Score=196, Evalue=7e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_STRP2 (Q04JX2)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_816676.1
- ProteinModelPortal:   Q04JX2
- SMR:   Q04JX2
- STRING:   Q04JX2
- EnsemblBacteria:   EBSTRT00000020550
- GeneID:   4442142
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_1209
- eggNOG:   COG0337
- GeneTree:   EBGT00050000027456
- HOGENOM:   HBG632303
- OMA:   CEIKAEV
- ProtClustDB:   PRK00002
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 39031; Mature: 39031

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNHVASLYAEKVKLSLEDA
CEEEEECCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHEEECCC
GFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVALGGGVVGDLAGFVASTYMR
CCEEEEEEHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHC
GIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQPDGVLIDPLVLETLGKRELIE
CEEEEEECCHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCEECHHHHHHCCHHHHHH
GMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLIEHSCQVKRKMVVEDELDNGIRL
HHHHHHHCCCCCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
YLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISKIAEEKGLMPAGITQSITEMCQKFG
EEECCCHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
LPVDYENWEVDKLYQALTHDKKARGNTLKLVLVPELGSATIHPVSLEEMKDYLVK
CCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEEECCCCCEECCCCHHHHHHHHCC
>Mature Secondary Structure
MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNHVASLYAEKVKLSLEDA
CEEEEECCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHEEECCC
GFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVALGGGVVGDLAGFVASTYMR
CCEEEEEEHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHC
GIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQPDGVLIDPLVLETLGKRELIE
CEEEEEECCHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCEECHHHHHHCCHHHHHH
GMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLIEHSCQVKRKMVVEDELDNGIRL
HHHHHHHCCCCCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
YLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISKIAEEKGLMPAGITQSITEMCQKFG
EEECCCHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
LPVDYENWEVDKLYQALTHDKKARGNTLKLVLVPELGSATIHPVSLEEMKDYLVK
CCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEEECCCCCEECCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA