Click here to switch to the map view.

The map label for this gene is licC [H]

Identifier: 116516696

GI number: 116516696

Start: 221135

End: 222433

Strand: Direct

Name: licC [H]

Synonym: SPD_0234

Alternate gene names: 116516696

Gene position: 221135-222433 (Clockwise)

Preceding gene: 116515458

Following gene: 116515577

Centisome position: 10.81

GC content: 35.95

Gene sequence:

>1299_bases
ATGGCAAAGATGGATGTTCAGAAAATCATTGCACCGATGATGAAGTTTGTGAATATGCGTGGCATTATAGCTCTAAAAGA
TGGGATGTTAGCAATTTTGCCATTGACAGTAGTTGGTAGTTTATTCTTGATTATGGGACAATTGCCGTTCGAAGGATTAA
ATAAGAGTATTGCTAGTGTTTTTGGAGCTAATTGGACAGAGCCGTTTATGCAAGTATATTCAGGAACTTTTGCTATTATG
GGTCTAATTTCTTGTTTTTCAATTGCCTATTCTTATGCTAAGAATAGCGGAGTAGAGGCTTTACCAGCTGGAGTTCTATC
TGTATCTGCATTCTTTATTTTGCTAAGATCATCTTATATCCCTAAACAAGGTGAGGCGATTGGGGACGCTATTAGTAAAG
TTTGGTTTGGAGGCCAAGGAATTATCGGTGCTATCATTATAGGTTTGGTAGTAGGAAGTATTTATACCTTCTTTATAAAG
AGAAAAATTGTTATTAAGATGCCAGAACAAGTTCCACAAGCTATTGCCAAACAGTTTGAAGCAATGATTCCAGCATTTGT
AATTTTCTTACTTTCTATGATTGTATATATTTTAGCGAAGTCATTGACTAATGGCGGAACATTCATAGAAATGATTTATT
CTGCTATTCAAGTTCCATTGCAAGGTTTAACTGGATCTTTGTATGGTGCAATTGGAATTGCATTCTTTATATCATTTTTG
TGGTGGTTTGGTGTTCATGGACAATCGGTAGTAAATGGAGTAGTGACAGCTCTGCTTTTATCTAATCTTGATGCTAATAA
AGCTATGTTAGCCTCTGGTAATCTATCATTAGAAAATGGTGCACATATTGTTACTCAACAATTTTTAGATTCATTTTTAA
TTCTATCAGGTTCAGGGATTACGTTTGGTCTTGTAGTTGCCATGCTTTTTGCAGCAAAATCAAAACAATACCAAGCCTTA
GGAAAAGTTGCAGCTTTTCCAGCAATATTTAACGTAAATGAGCCAGTTGTATTTGGATTTCCGATTGTCATGAATCCAGT
TATGTTTGTACCTTTCATTCTTGTTCCTGTACTTGCAGCTGTGATAGTATATGGAGCTATTGCAACAGGTTTCATGCAGC
CATTCTCAGGGGTAACATTGCCTTGGAGTACACCAGCTATTTTATCAGGATTTTTGGTGGGTGGATGGCAAGGTGTTGTG
ACTCAGTTATTAGTATTGGTGATATCTACAGTGGTTTACTTTCCATTCTTTAAGATACAAGATCGTTTAGCTTACCAAAA
TGAAATCAAACAATCTTAG

Upstream 100 bases:

>100_bases
ATAGCTGTTATTCCGATGATGGACTATGGTATGTTAGATGGGAAAAAAGTATTAGATTTGGCCCTATCTTTGATTAGTGG
GTAAGAAAAGGAGATTTATT

Downstream 100 bases:

>100_bases
AGGTATTTGTGTGTTACTGTTAAACTCACACATTTGTGCTAAAAATTAGAGAGTTAAAATTTTTCTAGTTAAAAGCTTGA
AAATTTCTATAAAAATCGGT

Product: PTS system, IIC component

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Lic; PTS system lichenan-specific EIIC component [H]

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MAKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLIMGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIM
GLISCFSIAYSYAKNSGVEALPAGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLLSMIVYILAKSLTNGGTFIEMIYSAIQVPLQGLTGSLYGAIGIAFFISFL
WWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLSLENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQAL
GKVAAFPAIFNVNEPVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFLVGGWQGVV
TQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS

Sequences:

>Translated_432_residues
MAKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLIMGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIM
GLISCFSIAYSYAKNSGVEALPAGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLLSMIVYILAKSLTNGGTFIEMIYSAIQVPLQGLTGSLYGAIGIAFFISFL
WWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLSLENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQAL
GKVAAFPAIFNVNEPVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFLVGGWQGVV
TQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS
>Mature_431_residues
AKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLIMGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMG
LISCFSIAYSYAKNSGVEALPAGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIKR
KIVIKMPEQVPQAIAKQFEAMIPAFVIFLLSMIVYILAKSLTNGGTFIEMIYSAIQVPLQGLTGSLYGAIGIAFFISFLW
WFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLSLENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALG
KVAAFPAIFNVNEPVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFLVGGWQGVVT
QLLVLVISTVVYFPFFKIQDRLAYQNEIKQS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=453, Percent_Identity=35.5408388520971, Blast_Score=221, Evalue=1e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 46506; Mature: 46375

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCC
>Mature Secondary Structure 
AKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLIMGQLPFEGLNKSIASV
CCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALPAGVLSVSAFFILLRSSYI
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
PKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIKRKIVIKMPEQVPQAIAKQFE
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHH
AMIPAFVIFLLSMIVYILAKSLTNGGTFIEMIYSAIQVPLQGLTGSLYGAIGIAFFISFL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLSLENGAHIVTQQFLDSFLILSGSGI
HHHCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCH
TFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNEPVVFGFPIVMNPVMFVPFILVPVLAA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHH
VIVYGAIATGFMQPFSGVTLPWSTPAILSGFLVGGWQGVVTQLLVLVISTVVYFPFFKIQ
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
DRLAYQNEIKQS
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]