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The map label for this gene is ywlC [H]

Identifier: 116516461

GI number: 116516461

Start: 919719

End: 920321

Strand: Direct

Name: ywlC [H]

Synonym: SPD_0908

Alternate gene names: 116516461

Gene position: 919719-920321 (Clockwise)

Preceding gene: 116517180

Following gene: 116515388

Centisome position: 44.95

GC content: 43.78

Gene sequence:

>603_bases
ATGATGGACAGGATTAGACAAGAGTTGGAAAAGGGTGGAGCTGTCGTTCTACCTACAGAGACTGTTTATGGTCTTTTTTC
CAAGGCCTTAGATGAAAAAGCAGTTGACCATGTTTACCAACTCAAACGTCGTCCTAGAGATAAGGCACTCAATCTCAATA
TCGCCTCTTTCGAGGACATCTTGCACTTTTCAAAGAATCAGCCAGCTTATCTACAAAAACTTGTAGAGACCTTTTTGCCA
GGTCCCTTGACCATTATTCTCGAAGCCAATGACCGAGTTCCCTATTGGGTAAATTCTGACCTTGCAACTATTGGATTTCG
GATGCCCAGTCACCCTATCACACTGGATTTAATTCGAGAGACAGGTCCCTTGATTGGGCCGTCTGCCAATATCTCAGGTC
AGGCAAGTGGTGTAACCTTTGAACAAATTCTGAAGGATTTTGACCAAGAGGTTCTGGGTCTGGAAGACGATGCTTTTCTA
ACTGGACAGGATTCAACTATTGTGGATTTGTCTGGAGACAAGGTGAAAATCTTACGCCAAGGCGCAATTAAACGAGAAGA
TATTCTTGCTCGGTTGCCAGAGATTTCTTTTGAGGAGGCTTGA

Upstream 100 bases:

>100_bases
CAAGGTCAATGTGTTCCCGAACTTTTTAGAAAACATCTTCCTGAAAAAAGAGTTCGAACACTCAAAGACCAATTTGGTCA
AAATAGGATGGTTGTGGTTG

Downstream 100 bases:

>100_bases
AATGCTAAGAGATTTGCAAGAAACAGATGTGAAAGCGATATGTGACATCAACCAAGAGGCTTTGGGTTATACTTTTAGTC
CAGAGGAAACGGCTAGCCAA

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MMDRIRQELEKGGAVVLPTETVYGLFSKALDEKAVDHVYQLKRRPRDKALNLNIASFEDILHFSKNQPAYLQKLVETFLP
GPLTIILEANDRVPYWVNSDLATIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA

Sequences:

>Translated_200_residues
MMDRIRQELEKGGAVVLPTETVYGLFSKALDEKAVDHVYQLKRRPRDKALNLNIASFEDILHFSKNQPAYLQKLVETFLP
GPLTIILEANDRVPYWVNSDLATIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA
>Mature_200_residues
MMDRIRQELEKGGAVVLPTETVYGLFSKALDEKAVDHVYQLKRRPRDKALNLNIASFEDILHFSKNQPAYLQKLVETFLP
GPLTIILEANDRVPYWVNSDLATIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=183, Percent_Identity=32.2404371584699, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI2367210, Length=136, Percent_Identity=28.6764705882353, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI87081864, Length=178, Percent_Identity=25.8426966292135, Blast_Score=63, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17537239, Length=182, Percent_Identity=31.3186813186813, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6321269, Length=193, Percent_Identity=30.0518134715026, Blast_Score=83, Evalue=3e-17,
Organism=Drosophila melanogaster, GI78707274, Length=177, Percent_Identity=31.638418079096, Blast_Score=74, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 22334; Mature: 22334

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDRIRQELEKGGAVVLPTETVYGLFSKALDEKAVDHVYQLKRRPRDKALNLNIASFEDI
CHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHH
LHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLATIGFRMPSHPITLDLIRE
HHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEECCCCEEEEEECCCCCEEHEEHHH
TGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLTGQDSTIVDLSGDKVKILRQ
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCEEEECCCCEEEEHHH
GAIKREDILARLPEISFEEA
CCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MMDRIRQELEKGGAVVLPTETVYGLFSKALDEKAVDHVYQLKRRPRDKALNLNIASFEDI
CHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHH
LHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLATIGFRMPSHPITLDLIRE
HHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEECCCCEEEEEECCCCCEEHEEHHH
TGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLTGQDSTIVDLSGDKVKILRQ
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCEEEECCCCEEEEHHH
GAIKREDILARLPEISFEEA
CCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]