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The map label for this gene is asd [H]

Identifier: 116516437

GI number: 116516437

Start: 912810

End: 913886

Strand: Direct

Name: asd [H]

Synonym: SPD_0900

Alternate gene names: 116516437

Gene position: 912810-913886 (Clockwise)

Preceding gene: 116515492

Following gene: 116516238

Centisome position: 44.61

GC content: 41.41

Gene sequence:

>1077_bases
ATGGGATATACAGTTGCTGTAGTCGGCGCGACAGGTGCTGTCGGTGCTCAGATGATAAAAATGTTGGAAGAATCAACACT
TCCAATCGATAAAATCCGTTACCTTGCTTCTGCACGTTCAGCAGGTAAGTCATTGAAATTTAAAGATCAAGATATTACAA
TTGAAGAAACGACTGAAACAGCTTTTGAAGGAGTTGATATTGCTCTCTTTTCAGCAGGTAGTTCTACATCAGCTAAGTAT
GCACCATACGCAGTAAAAGCTGGCGTGGTAGTAGTAGATAATACATCTTATTTCCGTCAAAATCCAGATGTTCCTTTGGT
TGTTCCAGAGGTCAATGCTCATGCACTTGATGCTCACAACGGAATCATTGCCTGCCCTAATTGTTCAACAATCCAAATGA
TGGTGGCTCTTGAGCCGGTTCGCCAAAAATGGGGCTTGGACCGTATCATTGTTTCAACTTATCAAGCCGTTTCAGGTGCT
GGTATGGGAGCAATTCTTGAGACACAACGTGAACTTCGTGAAGTCTTGAATGATGGTGTGAAACCATGTGATTTGCATGC
GGAAATTTTGCCTTCAGGTGGTGACAAGAAACATTATCCTATCGCCTTTAACGCTCTTCCACAAATTGATGTTTTCACTG
ATAATGATTACACGTACGAAGAGATGAAGATGACCAAGGAAACTAAGAAAATTATGGAAGATGATAGCATTGCAGTATCT
GCAACATGTGTGCGTATTCCAGTCTTGTCAGCTCACTCTGAGTCTGTTTATATCGAAACAAAAGAAGTGGCTCCAATCGA
AGAAGTAAAAGCAGCTATCGCAGCCTTCCCAGGTGCTGTTCTTGAAGATGATGTAGCTCATCAAATCTATCCTCAAGCTA
TCAATGCAGTTGGTTCACGTGATACCTTTGTTGGTCGTATCCGTAAAGACTTGGATGCAGAAAAAGGAATTCACATGTGG
GTTGTTTCAGATAACCTTCTCAAAGGTGCTGCTTGGAACTCAGTTCAGATTGCTGAAACTCTTCATGAACGTGGATTGGT
TCGTCCAACAGCTGAATTGAAATTTGAATTAAAATAG

Upstream 100 bases:

>100_bases
TATTTTCCAAAAAATGATGAAAAAGCTTTGCAATTCATGGAAAAAGTAGTATAATACTTCTATTATAGAAATTTTTAGAA
AATTCCGAAAGAGGTTATTT

Downstream 100 bases:

>100_bases
TCATATCGTTTAGGAGTTCAGATGAACTCCTTCTTTGAAATAGAGAGGTGTTTTCATGTCTTATCAAGATTTAAAAGAGT
GTAAAATCATCACAGCCTTT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKSLKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKY
APYAVKAGVVVVDNTSYFRQNPDVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYTYEEMKMTKETKKIMEDDSIAVS
ATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAFPGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMW
VVSDNLLKGAAWNSVQIAETLHERGLVRPTAELKFELK

Sequences:

>Translated_358_residues
MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKSLKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKY
APYAVKAGVVVVDNTSYFRQNPDVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYTYEEMKMTKETKKIMEDDSIAVS
ATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAFPGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMW
VVSDNLLKGAAWNSVQIAETLHERGLVRPTAELKFELK
>Mature_357_residues
GYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKSLKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYA
PYAVKAGVVVVDNTSYFRQNPDVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGAG
MGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYTYEEMKMTKETKKIMEDDSIAVSA
TCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAFPGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWV
VSDNLLKGAAWNSVQIAETLHERGLVRPTAELKFELK

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=343, Percent_Identity=32.9446064139942, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1789841, Length=368, Percent_Identity=26.3586956521739, Blast_Score=87, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320362, Length=403, Percent_Identity=29.2803970223325, Blast_Score=102, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 38925; Mature: 38794

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKSLKFKDQDITIEETTET
CCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEECCCCEEEEECHHH
AFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNPDVPLVVPEVNAHALDAHN
HHCCCEEEEEECCCCCCCCCCCEEEECCEEEEECCHHHHCCCCCCEEEECCCCEEEECCC
GIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGAGMGAILETQRELREVLNDGV
CEEECCCCCEEEEEEHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
KPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYTYEEMKMTKETKKIMEDDSIAVS
CCEECEEEECCCCCCCCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEE
ATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAFPGAVLEDDVAHQIYPQAINAVGSR
EEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
DTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNSVQIAETLHERGLVRPTAELKFELK
HHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCHHEEEEEC
>Mature Secondary Structure 
GYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKSLKFKDQDITIEETTET
CEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEECCCCEEEEECHHH
AFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNPDVPLVVPEVNAHALDAHN
HHCCCEEEEEECCCCCCCCCCCEEEECCEEEEECCHHHHCCCCCCEEEECCCCEEEECCC
GIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGAGMGAILETQRELREVLNDGV
CEEECCCCCEEEEEEHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
KPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYTYEEMKMTKETKKIMEDDSIAVS
CCEECEEEECCCCCCCCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEE
ATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAFPGAVLEDDVAHQIYPQAINAVGSR
EEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
DTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNSVQIAETLHERGLVRPTAELKFELK
HHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCHHEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2434499; 12397186 [H]