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The map label for this gene is dapA [H]

Identifier: 116516238

GI number: 116516238

Start: 913942

End: 914877

Strand: Direct

Name: dapA [H]

Synonym: SPD_0901

Alternate gene names: 116516238

Gene position: 913942-914877 (Clockwise)

Preceding gene: 116516437

Following gene: 116516420

Centisome position: 44.67

GC content: 42.95

Gene sequence:

>936_bases
ATGTCTTATCAAGATTTAAAAGAGTGTAAAATCATCACAGCCTTTATTACTCCCTTCCACGAGGATGGTTCCATCAACTT
TGATGCTATTCCAGCCTTGATTGAGCATTTATTGGACCATCATACGGATGGAATTCTTCTCGCAGGGACCACTGCTGAGA
GTCCAACTTTGACCCACGATGAGGAGTTGGAGTTATTTGCGGCTGTACAAAAGATTGTCAATGGACGAGTTCCTTTGATT
GCGGGTGTAGGTACTAATGATACGCGTGACTCTATCGAGTTTGTCAAAGAAGTAGCGGAATTCGGCGGTTTTGCTGCTGG
TCTTGCTATTGTTCCTTACTACAACAAACCTTCTCAAGAAGGAATGTATCAGCATTTTAAAGCCATTGCAGATGCTTCTG
ACCTACCAATTATTATCTATAACATTCCAGGGCGTGTGGTTGTTGAATTAACTCCAGAAACCATGCTTCGCTTGGCTGAT
CATCCAAATATTATCGGTGTCAAAGAATGTACTAGCTTGGCTAATATGGCTTACTTGATTGAGCACAAACCAGAAGAGTT
CTTGGTCTATACTGGTGAGGATGGAGATGCTTTCCATGCCATGAACCTTGGGGCGGATGGGGTTATTTCTGTTGCCTCTC
ATACAAATGGGGATGAAATGCACGAGATGTTTATTGCCATTGCAGAAAGTGATGTGAAGAAAGCCGCAGCTATTCAACGT
AAATTCATTCCTAAGGTTAATGCTCTCTTCTCTTATCCAAGTCCTGCTCCAGTTAAGGCAGTTTTGAACTACATGGGATT
TGAAGCTGGACCAACTCGTCTACCTCTTGTTCCAGCACCAGAAGAAGATGCTAAACGCATTATCAAGGTTGTCGTAGATG
GCGACTACGAAGCGACCAAGGCAACTGTAACAGGTGTCTTAAGACCAGATTACTAA

Upstream 100 bases:

>100_bases
GGATTGGTTCGTCCAACAGCTGAATTGAAATTTGAATTAAAATAGTCATATCGTTTAGGAGTTCAGATGAACTCCTTCTT
TGAAATAGAGAGGTGTTTTC

Downstream 100 bases:

>100_bases
TAAAGACAATAAAATCCATGACCGAATGAAGGATCATGGATTTTTCTTATTTTCCTAAACAGAATTGGCTAAAGAGTTGG
GTGATGAGTTCATCTGGAGT

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLDHHTDGILLAGTTAESPTLTHDEELELFAAVQKIVNGRVPLI
AGVGTNDTRDSIEFVKEVAEFGGFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
HPNIIGVKECTSLANMAYLIEHKPEEFLVYTGEDGDAFHAMNLGADGVISVASHTNGDEMHEMFIAIAESDVKKAAAIQR
KFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPLVPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY

Sequences:

>Translated_311_residues
MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLDHHTDGILLAGTTAESPTLTHDEELELFAAVQKIVNGRVPLI
AGVGTNDTRDSIEFVKEVAEFGGFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
HPNIIGVKECTSLANMAYLIEHKPEEFLVYTGEDGDAFHAMNLGADGVISVASHTNGDEMHEMFIAIAESDVKKAAAIQR
KFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPLVPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY
>Mature_310_residues
SYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLDHHTDGILLAGTTAESPTLTHDEELELFAAVQKIVNGRVPLIA
GVGTNDTRDSIEFVKEVAEFGGFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLADH
PNIIGVKECTSLANMAYLIEHKPEEFLVYTGEDGDAFHAMNLGADGVISVASHTNGDEMHEMFIAIAESDVKKAAAIQRK
FIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPLVPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=279, Percent_Identity=25.8064516129032, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI13540533, Length=297, Percent_Identity=27.6094276094276, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI1788823, Length=269, Percent_Identity=39.7769516728625, Blast_Score=201, Evalue=6e-53,
Organism=Escherichia coli, GI87082415, Length=294, Percent_Identity=27.891156462585, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1786463, Length=256, Percent_Identity=28.90625, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1789620, Length=275, Percent_Identity=26.5454545454545, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 33894; Mature: 33763

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLDHHTDGILLAGTTAESPTLTHD
CCCCHHHHHEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCH
EELELFAAVQKIVNGRVPLIAGVGTNDTRDSIEFVKEVAEFGGFAAGLAIVPYYNKPSQE
HHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEECEEEEECCCCCCCH
GMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLADHPNIIGVKECTSLANMAYLI
HHHHHHHHHCCCCCCCEEEEECCCEEEEEECHHHHHHHHCCCCEEEHHHHHHHHHHHHHE
EHKPEEFLVYTGEDGDAFHAMNLGADGVISVASHTNGDEMHEMFIAIAESDVKKAAAIQR
ECCCCEEEEEECCCCCEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
KFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPLVPAPEEDAKRIIKVVVDGDYEATK
HHCCHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHEEEEECCCCCCCE
ATVTGVLRPDY
EEEEEEECCCC
>Mature Secondary Structure 
SYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLDHHTDGILLAGTTAESPTLTHD
CCCHHHHHEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCH
EELELFAAVQKIVNGRVPLIAGVGTNDTRDSIEFVKEVAEFGGFAAGLAIVPYYNKPSQE
HHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEECEEEEECCCCCCCH
GMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLADHPNIIGVKECTSLANMAYLI
HHHHHHHHHCCCCCCCEEEEECCCEEEEEECHHHHHHHHCCCCEEEHHHHHHHHHHHHHE
EHKPEEFLVYTGEDGDAFHAMNLGADGVISVASHTNGDEMHEMFIAIAESDVKKAAAIQR
ECCCCEEEEEECCCCCEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
KFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPLVPAPEEDAKRIIKVVVDGDYEATK
HHCCHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHEEEEECCCCCCCE
ATVTGVLRPDY
EEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA