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The map label for this gene is lacC

Identifier: 116516039

GI number: 116516039

Start: 1080279

End: 1081208

Strand: Reverse

Name: lacC

Synonym: SPD_1051

Alternate gene names: 116516039

Gene position: 1081208-1080279 (Counterclockwise)

Preceding gene: 116517129

Following gene: 116516368

Centisome position: 52.84

GC content: 40.75

Gene sequence:

>930_bases
ATGATTTTAACAGTCACAATGAACCCATCCATTGATATTTCCTATCCCTTGGATGAGTTGAAGATTGATACTGTCAATCG
TGTGGTGGATGTAACCAAAACGGCTGGTGGTAAGGGACTCAATGTTACCCGAGTACTTTCAGAATTTGGCGATTCTGTTC
TTGCTACTGGTTTAGTGGGTGGCAAACTTGGTGAGTTTTTGGTTGAACATATCGATAATCAAGTAAAGAAAGATTTCTTC
TCAATTCAGGGAGAAACTCGTAACTGTATCGCTATTCTCCACGGAGACAACCAAACAGAAGTTCTTGAAAAAGGTCCTGA
AGTATTGGAACAGGAAGGTCAAGACTTTTTGGAACATTTCAAAAAACTCTTGGAGTCAGTTGAAGTAGTGGCCATCTCAG
GTAGTCTGCCAGCTGGCCTTCCAGTTGATTACTATGCGAGCTTGGTAGAACTTGCTAATCAAGCTGGCAAGCCTGTAGTC
TTGGACTGCTCAGGTGCAGCACTTCAGGCTGTTCTTGAATCACCCCATAAACCAACAGTCATCAAACCAAATAATGAAGA
ATTGTCTCAGCTTCTTGGAAGAGAAGTTTCTGAGGATTTGGATGAATTAAAAGAAGTACTTCAAGAACCTTTGTTTGCAG
GGATTGAATGGATTATCGTTTCACTTGGTGCCAACGGTACTTTTGCCAAACATGGTGACACTTTCTACAAGGTAGATATT
CCTAGAATTCAGGTGGTAAATCCTGTTGGATCTGGAGACTCTACTGTGGCAGGAATTTCTTCAGGACTTCTTCACAAAGA
ATCGGATGCAGAATTACTCATCAAGGCAAATGTCCTTGGTATGCTCAATGCTCAAGAAAAAATGACTGGTCATGTCAACA
TGGCCAACTATCAAGCTCTATATGATCAATTAATAGTAAAAGAGGTATAA

Upstream 100 bases:

>100_bases
CACCTTGAAAGTCACAATGCTCAACAAACAGACGCAAACTTCTTTACAGAATTCCTTGAAAAATGGGATCGCGGAGAATA
CCACGACTAAGAGGTGACCT

Downstream 100 bases:

>100_bases
AATGGCTTTAACAGAACAAAAACGTGTACGCTTAGAAAAACTTTCTGATGAAAATGGTATCATCTCAGCTCTTGCATTTG
ACCAACGTGGTGCTTTGAAA

Product: tagatose-6-phosphate kinase

Products: NA

Alternate protein names: Phosphotagatokinase

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTRVLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFF
SIQGETRNCIAILHGDNQTEVLEKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWIIVSLGANGTFAKHGDTFYKVDI
PRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKANVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV

Sequences:

>Translated_309_residues
MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTRVLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFF
SIQGETRNCIAILHGDNQTEVLEKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWIIVSLGANGTFAKHGDTFYKVDI
PRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKANVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV
>Mature_309_residues
MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTRVLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFF
SIQGETRNCIAILHGDNQTEVLEKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWIIVSLGANGTFAKHGDTFYKVDI
PRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKANVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family. LacC subfamily

Homologues:

Organism=Escherichia coli, GI1788493, Length=286, Percent_Identity=30.7692307692308, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788017, Length=297, Percent_Identity=27.9461279461279, Blast_Score=95, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LACC_STRP2 (Q04KC3)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_816525.1
- ProteinModelPortal:   Q04KC3
- SMR:   Q04KC3
- STRING:   Q04KC3
- EnsemblBacteria:   EBSTRT00000020403
- GeneID:   4441699
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_1051
- eggNOG:   COG1105
- GeneTree:   EBGT00050000027718
- HOGENOM:   HBG670529
- OMA:   NSGEYLN
- ProtClustDB:   PRK13508
- HAMAP:   MF_01557
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR005926
- InterPro:   IPR017583
- TIGRFAMs:   TIGR03168
- TIGRFAMs:   TIGR01231

Pfam domain/function: PF00294 PfkB

EC number: =2.7.1.144

Molecular weight: Translated: 33387; Mature: 33387

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS00583 PFKB_KINASES_1; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTRVLSEFGDSVLATGLVG
CEEEEEECCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHH
GKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVLEKGPEVLEQEGQDFLEHF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHCCHHHHHHCCHHHHHHH
KKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVVLDCSGAALQAVLESPHKPTV
HHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCE
IKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWIIVSLGANGTFAKHGDTFYKVDI
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEECCCCCCCCCCCEEEEEEC
PRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKANVLGMLNAQEKMTGHVNMANYQAL
CEEEEECCCCCCCCHHHHHHHCCCCCCCCCEEEEEECHHHHCCCHHHHCCCCCHHHHHHH
YDQLIVKEV
HHHHHHHCC
>Mature Secondary Structure
MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTRVLSEFGDSVLATGLVG
CEEEEEECCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHH
GKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVLEKGPEVLEQEGQDFLEHF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHCCHHHHHHCCHHHHHHH
KKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVVLDCSGAALQAVLESPHKPTV
HHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCE
IKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWIIVSLGANGTFAKHGDTFYKVDI
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEECCCCCCCCCCCEEEEEEC
PRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKANVLGMLNAQEKMTGHVNMANYQAL
CEEEEECCCCCCCCHHHHHHHCCCCCCCCCEEEEEECHHHHCCCHHHHCCCCCHHHHHHH
YDQLIVKEV
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA