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The map label for this gene is lacB

Identifier: 116517129

GI number: 116517129

Start: 1081219

End: 1081734

Strand: Reverse

Name: lacB

Synonym: SPD_1052

Alternate gene names: 116517129

Gene position: 1081734-1081219 (Counterclockwise)

Preceding gene: 116515890

Following gene: 116516039

Centisome position: 52.87

GC content: 39.53

Gene sequence:

>516_bases
ATGAGAATTGCAATTGGATGCGACCACATCGTAACAGATGAAAAAATGGCGGTTTCAGAATTTTTGAAATCAAAAGGATA
TGAAGTCATTGACTTTGGTACATATGACCATACACGGACTCACTACCCAATCTTTGGTAAAAAAGTAGGGGAAGCTGTAA
CTAGCGGCCAAGCTGATCTTGGGGTATGTATCTGTGGTACTGGTGTTGGTATCAACAACGCTGTAAATAAAGTTCCAGGT
GTTCGTTCTGCCTTGGTTCGTGATATGACAACAGCCCTTTATGCTAAAGAACAATTGAACGCTAACGTTATCGGCTTTGG
TGGTAAGATTACTGGTGAATTGCTTATGTGTGATATCATCGAAGCTTTCATTCATGCTGAATACAAACCATCTGAAGAAA
ACAAGAAATTGATTGCGAAAATTGAACACCTTGAAAGTCACAATGCTCAACAAACAGACGCAAACTTCTTTACAGAATTC
CTTGAAAAATGGGATCGCGGAGAATACCACGACTAA

Upstream 100 bases:

>100_bases
ATTTGTTAACGGTAAATACGATGGTGGACGTCATCAAATCCGGGTCGACATGTTGAACAAAATGGGCTAATTAGATTACA
GTAAGAAAGGTAAGTTAAAA

Downstream 100 bases:

>100_bases
GAGGTGACCTATGATTTTAACAGTCACAATGAACCCATCCATTGATATTTCCTATCCCTTGGATGAGTTGAAGATTGATA
CTGTCAATCGTGTGGTGGAT

Product: galactose-6-phosphate isomerase subunit LacB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPIFGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPG
VRSALVRDMTTALYAKEQLNANVIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
LEKWDRGEYHD

Sequences:

>Translated_171_residues
MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPIFGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPG
VRSALVRDMTTALYAKEQLNANVIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
LEKWDRGEYHD
>Mature_171_residues
MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPIFGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPG
VRSALVRDMTTALYAKEQLNANVIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
LEKWDRGEYHD

Specific function: In Addition To Its Activity On D-Ribose 5-Phosphate It Probably Also Has Activity On D-Allose 6-Phosphate. [C]

COG id: COG0698

COG function: function code G; Ribose 5-phosphate isomerase RpiB

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacAB/rpiB family

Homologues:

Organism=Escherichia coli, GI1790528, Length=136, Percent_Identity=36.0294117647059, Blast_Score=99, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LACB_STRP2 (Q04KC2)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_816526.1
- ProteinModelPortal:   Q04KC2
- SMR:   Q04KC2
- STRING:   Q04KC2
- EnsemblBacteria:   EBSTRT00000020524
- GeneID:   4442367
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_1052
- eggNOG:   COG0698
- GeneTree:   EBGT00050000027286
- HOGENOM:   HBG636953
- OMA:   ETHHANQ
- ProtClustDB:   PRK08622
- HAMAP:   MF_01556
- InterPro:   IPR004784
- InterPro:   IPR003500
- Gene3D:   G3DSA:3.40.1400.10
- PIRSF:   PIRSF005384
- TIGRFAMs:   TIGR01119
- TIGRFAMs:   TIGR00689

Pfam domain/function: PF02502 LacAB_rpiB; SSF89623 Rib/Gal_isomrase

EC number: =5.3.1.26

Molecular weight: Translated: 18958; Mature: 18958

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPIFGKKVGEAVTSGQADL
CEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCC
GVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNANVIGFGGKITGELLMCDII
EEEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHH
EAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEFLEKWDRGEYHD
HHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPIFGKKVGEAVTSGQADL
CEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCC
GVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNANVIGFGGKITGELLMCDII
EEEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHH
EAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEFLEKWDRGEYHD
HHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA