BacMap

Definition	Streptococcus pneumoniae D39, complete genome.
Accession	NC_008533
Length	2,046,115

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The map label for this gene is yqjQ [H]

Identifier: 116515980

GI number: 116515980

Start: 613612

End: 614367

Strand: Direct

Name: yqjQ [H]

Synonym: SPD_0587

Alternate gene names: 116515980

Gene position: 613612-614367 (Clockwise)

Preceding gene: 116516699

Following gene: 116516426

Centisome position: 29.99

GC content: 42.33

Gene sequence:

>756_bases
ATGCCTACTATTCTCATTACCGGAGCTAGCGGTGGTCTAGCTCAAGAAATGGTCAAACTCCTGCCCAATGACCAACTCAT
CTTGCTTGGTAGAAATAAGGAAAAATTAGCCCAACTCTACGGAAATTATTCCCATGCAGAATTGATTGAAATTGATATTA
CCGACGATTCAGCCCTAGAAGCTCTGGTAACTGATCTTTATCTCCGCTATGGCAAGATTGATGTCTTGATTAACAACGCT
GGTTACGGGATTTTTGAGGGATTTGACCAGATTGCTGATAAAGATATTCACCAGATGTTTGAGGTCAATACCTTTGCCCT
GATGAATCTGTCTCGTCACCTTGCGGCTCGTATGAAGGAAAGCAGCAAAGGGCATATCATCAACATCGTCAGCATGGCAG
GTCTAATAGCTACTGGCAAGTCTAGTCTTTACTCAGCGACCAAGTTTGCGGCTATTGGTTTTTCAAATGCTCTGCGACTC
GAACTTATGCCCTATGGAGTCTATGTGACAACAGTCAATCCAGGACCAATCCGTACAGGATTTTTCGACCAAGCCGACCC
AGATGGAACTTATCTTAAATCGGTTGATCGCTTCCTGCTAGAACCAGATGCAGTGGCTAAAAAGATTGTCAAGATTATAG
GAAAAAACAAACGAGAACTCAATCTCCCGATTTTGTTGAACCTAGCTCATAAGTTTTATACCCTCTTTCCTAAGCTAGCT
GATAAGTTGGCAGGGGAAACTTTTAATTATAAGTAA

Upstream 100 bases:

>100_bases
TTAGCAAACTCAAGAAAGACGCTGCCACAATTTTTGAAAATGTCCATGTGGTCAAAGACTTGGAAGAAGTGGAAATCTAG
CAGTCACAGAAAGGATAAGT

Downstream 100 bases:

>100_bases
AAAGAACCAATGTGCAGGTTGTTGCTAGCCTACATATTGGTTCTTATCATTTCTCAACTATCAAACTGAACTTCTTCTAG
GAGATAGTCTATAAAGCGTT

Product: oxidoreductase, short chain dehydrogenase/reductase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYSHAELIEIDITDDSALEALVTDLYLRYGKIDVLINNA
GYGIFEGFDQIADKDIHQMFEVNTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKRELNLPILLNLAHKFYTLFPKLA
DKLAGETFNYK

Sequences:

>Translated_251_residues
MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYSHAELIEIDITDDSALEALVTDLYLRYGKIDVLINNA
GYGIFEGFDQIADKDIHQMFEVNTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKRELNLPILLNLAHKFYTLFPKLA
DKLAGETFNYK
>Mature_250_residues
PTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYSHAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAG
YGIFEGFDQIADKDIHQMFEVNTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRLE
LMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKRELNLPILLNLAHKFYTLFPKLAD
KLAGETFNYK

Specific function: Unknown

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=255, Percent_Identity=32.156862745098, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI7657478, Length=251, Percent_Identity=27.0916334661355, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI4503817, Length=222, Percent_Identity=27.9279279279279, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI157739938, Length=236, Percent_Identity=25.4237288135593, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI7706318, Length=193, Percent_Identity=27.4611398963731, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI109715829, Length=226, Percent_Identity=26.9911504424779, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI59889578, Length=151, Percent_Identity=31.1258278145695, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI223718074, Length=196, Percent_Identity=25.5102040816327, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI40807363, Length=236, Percent_Identity=29.2372881355932, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI142976729, Length=231, Percent_Identity=26.8398268398268, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI210032110, Length=251, Percent_Identity=25.8964143426295, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI40548397, Length=180, Percent_Identity=30, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI214010158, Length=180, Percent_Identity=30, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI214010156, Length=180, Percent_Identity=30, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI22758144, Length=180, Percent_Identity=30, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI7705925, Length=189, Percent_Identity=26.984126984127, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI7705855, Length=209, Percent_Identity=28.7081339712919, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI210032112, Length=176, Percent_Identity=27.8409090909091, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI31542939, Length=233, Percent_Identity=23.6051502145923, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1786701, Length=234, Percent_Identity=29.9145299145299, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1787820, Length=220, Percent_Identity=28.1818181818182, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787335, Length=178, Percent_Identity=28.6516853932584, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87082100, Length=196, Percent_Identity=27.5510204081633, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI87082160, Length=181, Percent_Identity=28.7292817679558, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI2367365, Length=183, Percent_Identity=28.9617486338798, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788459, Length=172, Percent_Identity=30.2325581395349, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1790717, Length=184, Percent_Identity=26.0869565217391, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=196, Percent_Identity=32.6530612244898, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI193203115, Length=257, Percent_Identity=30.7392996108949, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI193203117, Length=257, Percent_Identity=30.7392996108949, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17508895, Length=259, Percent_Identity=27.4131274131274, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17563726, Length=217, Percent_Identity=29.4930875576037, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=192, Percent_Identity=28.125, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=202, Percent_Identity=26.2376237623762, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=209, Percent_Identity=26.3157894736842, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=193, Percent_Identity=27.4611398963731, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=201, Percent_Identity=29.8507462686567, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=193, Percent_Identity=26.9430051813472, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=234, Percent_Identity=29.9145299145299, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=202, Percent_Identity=29.2079207920792, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=196, Percent_Identity=27.0408163265306, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=195, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=196, Percent_Identity=28.0612244897959, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=237, Percent_Identity=24.0506329113924, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=191, Percent_Identity=25.130890052356, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=256, Percent_Identity=26.171875, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=192, Percent_Identity=29.6875, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115534660, Length=209, Percent_Identity=26.3157894736842, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=196, Percent_Identity=28.0612244897959, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=217, Percent_Identity=30.4147465437788, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=199, Percent_Identity=26.6331658291457, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71997402, Length=234, Percent_Identity=28.6324786324786, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=192, Percent_Identity=27.0833333333333, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=223, Percent_Identity=25.5605381165919, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=193, Percent_Identity=33.160621761658, Blast_Score=95, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6322067, Length=191, Percent_Identity=34.0314136125654, Blast_Score=79, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6323458, Length=233, Percent_Identity=30.0429184549356, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322227, Length=241, Percent_Identity=29.045643153527, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320089, Length=244, Percent_Identity=28.2786885245902, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24643142, Length=189, Percent_Identity=32.2751322751323, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI28571526, Length=209, Percent_Identity=31.5789473684211, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI221510726, Length=173, Percent_Identity=34.6820809248555, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24581726, Length=198, Percent_Identity=26.7676767676768, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21358495, Length=253, Percent_Identity=26.4822134387352, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21357041, Length=201, Percent_Identity=29.3532338308458, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356301, Length=165, Percent_Identity=29.6969696969697, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI23397609, Length=183, Percent_Identity=30.0546448087432, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281364892, Length=249, Percent_Identity=28.1124497991968, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24644339, Length=206, Percent_Identity=28.1553398058252, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28571387, Length=226, Percent_Identity=27.4336283185841, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24580925, Length=196, Percent_Identity=27.0408163265306, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27777; Mature: 27645

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYSHAELIEIDITDDSALE
CCEEEEECCCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCCCEEEEEEECCCHHHH
ALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEVNTFALMNLSRHLAARMKE
HHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
SSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRLELMPYGVYVTTVNPGPIRTG
CCCCCEEEEEHHHHHHHCCCHHHHHHHHHHEECCCCCEEEEEEEEEEEEEEECCCCCCCC
FFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKRELNLPILLNLAHKFYTLFPKLA
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHH
DKLAGETFNYK
HHHCCCCCCCC
>Mature Secondary Structure 
PTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYSHAELIEIDITDDSALE
CEEEEECCCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCCCEEEEEEECCCHHHH
ALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEVNTFALMNLSRHLAARMKE
HHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
SSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRLELMPYGVYVTTVNPGPIRTG
CCCCCEEEEEHHHHHHHCCCHHHHHHHHHHEECCCCCEEEEEEEEEEEEEEECCCCCCCC
FFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKRELNLPILLNLAHKFYTLFPKLA
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHH
DKLAGETFNYK
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]