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The map label for this gene is murG

Identifier: 116515971

GI number: 116515971

Start: 624258

End: 625316

Strand: Direct

Name: murG

Synonym: SPD_0599

Alternate gene names: 116515971

Gene position: 624258-625316 (Clockwise)

Preceding gene: 116515762

Following gene: 116517041

Centisome position: 30.51

GC content: 42.3

Gene sequence:

>1059_bases
ATGAAAAAAATTGTCTTTACAGGTGGGGGGACGGTTGGACACGTTACCCTCAATCTTTTGTTAATGCCCAAGTTCATCGA
AGATGGTTGGGAAGTCCACTATATCGGGGACAAGCGTGGTATCGAACACCAAGAAATCCTTAAGTCAGGTTTGGATGTCA
CTTTCCACTCCATTGCGACTGGGAAATTGCGTCGCTATTTCTCTTGGCAAAATATGCTGGACGTCTTCAAAGTTGGCTGG
GGAATCGTCCAATCGCTCTTTATCATGTTGCGACTTCGTCCACAGACCCTTTTTTCAAAGGGGGGCTTTGTCTCAGTACC
GCCTGTTATCGCAGCGCGTGTGTCAGGAGTGCCTGTCTTTATTCACGAATCTGACCTGTCTATGGGCTTGGCCAATAAAA
TCGCCTATAAATTTGCGACTAAGATGTATTCAACCTTTGAGCAAGCTTCGAGTTTGTCTAAGGTTGAGCATGTGGGAGCA
GTGACCAAGGTTTCAGATCAAAAAAATCCAGAACCAGATGAATTGGTGGATATTCAAACCCACTTTAATCATAAATTGCC
GACTGTATTGTTTGTTGGCGGTTCTGCAGGTGCTCGTGTCTTTAACCAATTGGTGACAGACCATAAGAAAGAACTAACAG
AGCGCTACAATATTATCAATCTAACTGGAGATTCTAGTCTGAACGAGTTGAGCCAAAATCTTTTTCGTGTTGACTATGTG
ACCGATCTCTATCAACCCTTGATGGAATTGGCTGATATTGTTGTGACACGAGGTGGTGCCAATACGATTTTTGAGCTCTT
GGCGATAGCAAAATTGCATGTCATTGTGCCGCTTGGTCGTGAAGCTAGTCGTGGTGACCAGATTGAAAATGCAGCTTACT
TTGTAAAAAAAGGCTATGCAGAAGACCTTCAAGAAAGCGATTTGACCTTGGATAGTTTGGAAGAGAAGCTTTCTCACTTA
CTAAGTCACAAGGAAGATTACCAAGCTAAGATGAAAGCTTCTAAGGAATTGAAATCTCTAGCAGATTTTTATCAATTGTT
GAAAAAAGATTTATCATAA

Upstream 100 bases:

>100_bases
TCTTCTTAGTCCTGCCAATGCCAGCTGGGATATGTATGCTAACTTTGAAGTACGTGGCGACCTCTTTATCGACACAGTAG
CGGAGTTAAAAGAATAAAAT

Downstream 100 bases:

>100_bases
GGAAAGTAAATGTCAAAAGATAAGAAAAATGAGGACAAAGAAACCCTCGAAGAATTGAAAGAGTTATCAGAATGGCAGAA
ACGAAACCAAGAATATCTAA

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQEILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGW
GIVQSLFIMLRLRPQTLFSKGGFVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
VTKVSDQKNPEPDELVDIQTHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNIINLTGDSSLNELSQNLFRVDYV
TDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIVPLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHL
LSHKEDYQAKMKASKELKSLADFYQLLKKDLS

Sequences:

>Translated_352_residues
MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQEILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGW
GIVQSLFIMLRLRPQTLFSKGGFVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
VTKVSDQKNPEPDELVDIQTHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNIINLTGDSSLNELSQNLFRVDYV
TDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIVPLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHL
LSHKEDYQAKMKASKELKSLADFYQLLKKDLS
>Mature_352_residues
MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQEILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGW
GIVQSLFIMLRLRPQTLFSKGGFVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
VTKVSDQKNPEPDELVDIQTHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNIINLTGDSSLNELSQNLFRVDYV
TDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIVPLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHL
LSHKEDYQAKMKASKELKSLADFYQLLKKDLS

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=336, Percent_Identity=27.6785714285714, Blast_Score=108, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_STRP2 (Q04LK0)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_816098.1
- ProteinModelPortal:   Q04LK0
- SMR:   Q04LK0
- STRING:   Q04LK0
- EnsemblBacteria:   EBSTRT00000020162
- GeneID:   4442422
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_0599
- eggNOG:   COG0707
- GeneTree:   EBGT00050000027764
- HOGENOM:   HBG617076
- OMA:   HICGKGN
- ProtClustDB:   PRK00726
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39449; Mature: 39449

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQEILKSGLDVTFHSIAT
CCEEEEECCCCEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCEEHHHHHH
GKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGGFVSVPPVIAARVSGVPVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEECCHHHHHHHCCCEEE
IHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGAVTKVSDQKNPEPDELVDIQT
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEHHH
HFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNIINLTGDSSLNELSQNLFRVDYV
HCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHH
TDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIVPLGREASRGDQIENAAYFVKKGYA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHCCH
EDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKASKELKSLADFYQLLKKDLS
HHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQEILKSGLDVTFHSIAT
CCEEEEECCCCEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCEEHHHHHH
GKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGGFVSVPPVIAARVSGVPVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEECCHHHHHHHCCCEEE
IHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGAVTKVSDQKNPEPDELVDIQT
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEHHH
HFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNIINLTGDSSLNELSQNLFRVDYV
HCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHH
TDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIVPLGREASRGDQIENAAYFVKKGYA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHCCH
EDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKASKELKSLADFYQLLKKDLS
HHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA