Click here to switch to the map view.

The map label for this gene is rpoC

Identifier: 116515724

GI number: 116515724

Start: 1751843

End: 1755520

Strand: Reverse

Name: rpoC

Synonym: SPD_1758

Alternate gene names: 116515724

Gene position: 1755520-1751843 (Counterclockwise)

Preceding gene: 116516435

Following gene: 116516942

Centisome position: 85.8

GC content: 46.17

Gene sequence:

>3678_bases
GTGGTTGATGTAAATCGTTTTAAAAGTATGCAAATCACCCTAGCTTCTCCAAGTAAAGTCCGTTCATGGTCTTATGGAGA
AGTCAAAAAACCTGAAACAATCAATTATCGTACCTTGAAACCAGAACGTGAAGGACTCTTTGATGAAGTGATCTTTGGTC
CTACAAAAGACTGGGAATGTGCTTGTGGTAAGTACAAACGCATTCGTTACAGAGGAATTGTTTGTGACCGCTGTGGGGTT
GAAGTAACGCGTACGAAAGTTCGTCGTGAGCGTATGGGACATATCGAATTGAAAGCTCCTGTATCTCACATCTGGTACTT
CAAGGGGATTCCAAGCCGTATGGGCTTGACCCTTGATATGAGCCCTCGTGCCCTCGAGGAAGTTATCTACTTTGCGGCTT
ATGTGGTGATTGATCCTAAGGATACACCACTTGAGCACAAGTCTATCATGACAGAGCGCGAATACCGAGAGCGCTTGCGC
GAATATGGTTATGGTTCATTTGTTGCTAAGATGGGTGCGGAAGCCATCCAAGACCTTTTGAAGCAAGTAGATCTTGAAAA
AGAAATTGCTGAACTCAAAGAAGAATTGAAAACTGCTACTGGACAAAAACGTGTCAAAGCCATCCGTCGTTTGGATGTTT
TGGATGCCTTTTACAAGTCTGGAAACAAACCTGAATGGATGATTCTTAACATCCTTCCGGTTATCCCACCAGATCTTCGT
CCAATGTTGCAGTTGGATGGTGGCCGTTTTGCCTCATCTGACTTGAATGACCTTTACCGCCGTGTTATCAACCGTAACAA
CCGTTTGGCTCGTTTGCTTGAGTTAAATGCACCAGGTATCATCGTTCAAAATGAGAAGCGTATGCTTCAAGAAGCAGTTG
ACGCTTTGATTGACAATGGTCGTCGTGGTCGTCCAATCACAGGACCAGGTAGCCGTCCATTGAAATCATTGAGCCACATG
CTTAAAGGTAAACAAGGACGCTTCCGTCAAAACTTGCTCGGTAAACGTGTTGACTTCTCAGGACGTTCCGTTATCGCCGT
TGGTCCAACTCTTAAGATGTACCAATGTGGTGTGCCACGTGAAATGGCGATTGAACTCTTTAAACCATTTGTCATGCGTG
AAATCGTTGCCCGTGATATCGTGCAAAACGTCAAAGCAGCTAAACGCTTGGTGGAACGCGGAGATGAGCGTATCTGGGAT
ATCCTTGAAGAAGTGATTAAAGAACACCCAGTGCTTTTGAACCGCGCACCGACCCTTCACCGTTTGGGTATCCAAGCCTT
CGAGCCAGTCTTGATTGATGGTAAGGCTCTTCGCTTGCACCCACTTGTCTGTGAAGCCTACAATGCTGACTTTGACGGGG
ACCAAATGGCCATCCACGTACCACTTTCAGAAGAAGCACAAGCAGAAGCTCGTATCCTCATGCTAGCTGCTGAGCACATC
TTGAACCCGAAAGATGGGAAACCGGTAGTTACTCCATCTCAGGACATGGTTTTGGGTAACTACTACTTGACCATGGAAGA
AGCTGGTCGCGAAGGTGAAGGAATGGTCTTCAAAGACCGTGACGAAGCGGTTATGGCTTACCGCAATGGTTATGTTCACC
TCCACTCACGTGTTGGTATCGCAACAGACAGCCTCAACAAGCCTTGGACAGAAGAGCAAAGACATAAGGTCTTGCTTACA
ACAGTTGGTAAAATTCTCTTCAACGATATCATGCCAGAGGGGCTACCATACTTGCAAGAACCAAACAATGCCAACTTGAC
AGAAGGTGTTCCAGCTAAATACTTCTTGCCACTTGGTGGAGCTATCAAGGAAGCTATCAGCAATCTTGAGCTCAACCCTC
CATTCAAGAAGAAAAACCTCGGAAATATCATCGCTGAAATCTTCAAACGTTTCCGTACGACAGAAACTTCTGCCCTACTT
GACCGCATGAAGAACCTCGGTTACCACCACTCAACTCTTGCAGGATTGACAGTGGGTATTGCCGATATCCCAGTCGTTGA
TGACAAGGCTGAAATCATTGAAGAATCACACAAACGTGTCGAACAAATCACCAAACAATTCCGTCGTGGTATGATCACAG
ACGACGAGCGTTACAATGCTGTTACAGCTGAATGGCGTGCTGCCCGTGAAAAACTTGAGAAACGCTTGATTGCTAATCAA
GATCCTAAGAACCCAATCGTTATGATGATGGACTCTGGAGCCCGTGGTAACATCTCAAACTTCTCACAGCTTGCCGGTAT
GCGTGGTCTGATGGCTGCTCCGAATGGACGTATCATGGAATTGCCAATCCTTTCAAACTTCCGCGAAGGTTTGTCGGTAT
TGGAAATGTTCTTCTCAACTCACGGTGCTCGTAAAGGTATGACCGATACGGCCCTTAAGACAGCCGACTCAGGTTACTTG
ACTCGTCGTTTGGTCGACGTTGCCCAAGACGTTATCATCCGTGAGGACGACTGTGGAACTGACCGTGGTCTCTTGATCCG
TTCTATCGCAGAAGGAAAAGAGATGATCGAGTCTCTCGAAGAGCGTCTCAACGGTCGTTACACTAAGAAAACTGTTAAAC
ATCCAGAAACTGGTGCAGTGATTATTGGTCCAAATGAATTGATTACAGAAGACAAGGCGCGTGAAATTGTCAATGCTGGT
GTGGAAGAAGTGACTATCCGTTCTGTATTTACATGTAACACTCGTCACGGTGTCTGCCGTCACTGTTACGGTATCAACTT
GGCGACTGGTGATGCGGTTGAAGTTGGTGAAGCAGTTGGTACAATCGCTGCCCAATCTATCGGGGAACCTGGTACACAGC
TTACAATGCGTACCTTCCACACAGGTGGGGTTGCCTCAAATACCGATATCACTCAGGGTCTTCCTCGTGTCCAAGAAATC
TTTGAAGCCCGCAATCCTAAAGGGGAAGCGGTTATTACAGAGGTTAAAGGACAAGTTACTGCTATCGAAGAAGATGCATC
AACTCGTACCAAGAAAGTCTTTGTTAAGGGTGAAACTGGCGAAGGTGAATATGTCGTTCCATTTACAGCTCGTATGCGTG
TCGAAGTTGGGGGCCAAGTAGCGCGTGGTGCTGCTCTGACAGAAGGTTCTATCCAACCAAAACGTCTCCTTGCAGTTCGT
GATGTCTTGTCAGTTGAAACGTACCTTCTCGGTGAAGTACAAAAAGTTTACCGTAGCCAAGGGGTAGAAATCGGTGACAA
ACACATCGAGGTAATGGTTCGTCAAATGATCCGTAAAGTCCGTGTCATGGATCCAGGTGATACAGATCTTCTCATGGGTA
CCCTCATGGATATCAATGACTTTACAGATGCCAACAAAGATGTCCTTATCGCAGGTGGAGTTCCAGCGACAGGTCGCCCA
GTCCTTATGGGAATTACCAAAGCCTCACTTGAAACAAACAGTTTCTTGTCAGCGGCTTCCTTCCAGGAAACAACTCGTGT
CCTTACTGACGCAGCTATCCGTGGTAAGAAAGACCATCTCCTTGGACTTAAAGAAAATGTTATCATCGGTAAGATCATCC
CAGCTGGTACTGGTATGGCCCGTTACCGTAACCTTGAACCACATGCTGTCAACGAAGAAGAATACCTTAATCCTCCAGTA
GAGGAAGAAGGAAATGAAGAAACAACAGAAGTAGTTGTGGATACTGCCGTTGAAACTGTGGAAGAAACAGTAGAATAA

Upstream 100 bases:

>100_bases
TTGAAGCTGAAGAAGCTGAGAAAGCAACAAAAGCGGAAGCAACAGAAGAAGCTGCTGAACAAGAATAAGCAGTTCACTTA
GAATAGAAAGGGAAGAAATA

Downstream 100 bases:

>100_bases
GAGAGAATGAGAGAACCCGAGGGTTCTCTCATTCTCTCTTCTGAAAACTTTCTCCATTTTTCCACGAAATGTGGTAAAAT
AAAAGAAAGAAGCTGACAAA

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1225; Mature: 1225

Protein sequence:

>1225_residues
MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPEREGLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGV
EVTRTKVRRERMGHIELKAPVSHIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFYKSGNKPEWMILNILPVIPPDLR
PMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELNAPGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHM
LKGKQGRFRQNLLGKRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVERGDERIWD
ILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNADFDGDQMAIHVPLSEEAQAEARILMLAAEHI
LNPKDGKPVVTPSQDMVLGNYYLTMEEAGREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLT
TVGKILFNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGAIKEAISNLELNPPFKKKNLGNIIAEIFKRFRTTETSALL
DRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQ
DPKNPIVMMMDSGARGNISNFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSGYL
TRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPETGAVIIGPNELITEDKAREIVNAG
VEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEI
FEARNPKGEAVITEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGSIQPKRLLAVR
DVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDTDLLMGTLMDINDFTDANKDVLIAGGVPATGRP
VLMGITKASLETNSFLSAASFQETTRVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPV
EEEGNEETTEVVVDTAVETVEETVE

Sequences:

>Translated_1225_residues
MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPEREGLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGV
EVTRTKVRRERMGHIELKAPVSHIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFYKSGNKPEWMILNILPVIPPDLR
PMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELNAPGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHM
LKGKQGRFRQNLLGKRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVERGDERIWD
ILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNADFDGDQMAIHVPLSEEAQAEARILMLAAEHI
LNPKDGKPVVTPSQDMVLGNYYLTMEEAGREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLT
TVGKILFNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGAIKEAISNLELNPPFKKKNLGNIIAEIFKRFRTTETSALL
DRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQ
DPKNPIVMMMDSGARGNISNFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSGYL
TRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPETGAVIIGPNELITEDKAREIVNAG
VEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEI
FEARNPKGEAVITEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGSIQPKRLLAVR
DVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDTDLLMGTLMDINDFTDANKDVLIAGGVPATGRP
VLMGITKASLETNSFLSAASFQETTRVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPV
EEEGNEETTEVVVDTAVETVEETVE
>Mature_1225_residues
MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPEREGLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGV
EVTRTKVRRERMGHIELKAPVSHIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFYKSGNKPEWMILNILPVIPPDLR
PMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELNAPGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHM
LKGKQGRFRQNLLGKRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVERGDERIWD
ILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNADFDGDQMAIHVPLSEEAQAEARILMLAAEHI
LNPKDGKPVVTPSQDMVLGNYYLTMEEAGREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLT
TVGKILFNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGAIKEAISNLELNPPFKKKNLGNIIAEIFKRFRTTETSALL
DRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQ
DPKNPIVMMMDSGARGNISNFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSGYL
TRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPETGAVIIGPNELITEDKAREIVNAG
VEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEI
FEARNPKGEAVITEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGSIQPKRLLAVR
DVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDTDLLMGTLMDINDFTDANKDVLIAGGVPATGRP
VLMGITKASLETNSFLSAASFQETTRVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPV
EEEGNEETTEVVVDTAVETVEETVE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI39725938, Length=1055, Percent_Identity=26.0663507109005, Blast_Score=239, Evalue=2e-62,
Organism=Homo sapiens, GI4505939, Length=858, Percent_Identity=25.6410256410256, Blast_Score=200, Evalue=7e-51,
Organism=Homo sapiens, GI103471997, Length=606, Percent_Identity=26.0726072607261, Blast_Score=139, Evalue=1e-32,
Organism=Escherichia coli, GI2367335, Length=1042, Percent_Identity=52.4952015355086, Blast_Score=1068, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25145495, Length=1063, Percent_Identity=24.5531514581374, Blast_Score=243, Evalue=6e-64,
Organism=Caenorhabditis elegans, GI71987878, Length=677, Percent_Identity=27.178729689808, Blast_Score=186, Evalue=9e-47,
Organism=Caenorhabditis elegans, GI71998295, Length=618, Percent_Identity=23.9482200647249, Blast_Score=119, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6320061, Length=891, Percent_Identity=25.364758698092, Blast_Score=216, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6324690, Length=719, Percent_Identity=26.5646731571627, Blast_Score=201, Evalue=4e-52,
Organism=Saccharomyces cerevisiae, GI6324917, Length=299, Percent_Identity=28.0936454849498, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281360912, Length=1077, Percent_Identity=25.255338904364, Blast_Score=246, Evalue=6e-65,
Organism=Drosophila melanogaster, GI17530899, Length=488, Percent_Identity=28.6885245901639, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI17647875, Length=720, Percent_Identity=24.3055555555556, Blast_Score=136, Evalue=8e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_STRP2 (Q04IK7)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_817181.1
- ProteinModelPortal:   Q04IK7
- STRING:   Q04IK7
- PhosSite:   Q04IK7
- EnsemblBacteria:   EBSTRT00000018833
- GeneID:   4442262
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_1758
- eggNOG:   COG0086
- GeneTree:   EBGT00050000028260
- HOGENOM:   HBG621785
- OMA:   FEARVPK
- ProtClustDB:   PRK00566
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 136947; Mature: 136947

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPEREGLFDEVIFGPTKDWEC
CCCCCCCCCEEEEECCCHHHCCCCCCCCCCCCCCCEEECCCHHHCCHHHHHCCCCCCCCH
ACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVSHIWYFKGIPSRMGLTLDM
HCCCHHEEEEECEEECCCCCHHHHHHHHHHHCCCEEEECCHHHEEEECCCCHHHCEEEEC
SPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLREYGYGSFVAKMGAEAIQDLL
CHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
KQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFYKSGNKPEWMILNILPVIPPDLR
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCC
PMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELNAPGIIVQNEKRMLQEAVDALIDNG
HHHEECCCCCCCCCHHHHHHHHHCCCCCEEHHEEECCCCEEEECHHHHHHHHHHHHHHCC
RRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLGKRVDFSGRSVIAVGPTLKMYQCGVPR
CCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCEEEEECCCEEEHCCCCCH
EMAIELFKPFVMREIVARDIVQNVKAAKRLVERGDERIWDILEEVIKEHPVLLNRAPTLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEECCCCCHH
RLGIQAFEPVLIDGKALRLHPLVCEAYNADFDGDQMAIHVPLSEEAQAEARILMLAAEHI
HHCHHHCCCEEECCCEEEEEHEEHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHEEHHHH
LNPKDGKPVVTPSQDMVLGNYYLTMEEAGREGEGMVFKDRDEAVMAYRNGYVHLHSRVGI
CCCCCCCEEECCCCCEEEEEEEEEEHHCCCCCCCCEEECCCCEEEEEECCEEEEECCCCE
ATDSLNKPWTEEQRHKVLLTTVGKILFNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGG
EECCCCCCCCHHHHHEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCH
AIKEAISNLELNPPFKKKNLGNIIAEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGI
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHEECC
ADIPVVDDKAEIIEESHKRVEQITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
DPKNPIVMMMDSGARGNISNFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFST
CCCCCEEEEECCCCCCCCHHHHHHHCCCCCEECCCCCEEEEHHHHHHHHHHHHHHHHHHH
HGARKGMTDTALKTADSGYLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLE
CCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHH
ERLNGRYTKKTVKHPETGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCR
HHHCCCCHHHHCCCCCCCEEEECCHHHHCCHHHHHHHHCCHHHEEEHHEEEECCCCCHHH
HCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEI
HHCCCEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHCCHHHHHH
FEARNPKGEAVITEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQV
HHCCCCCCCEEEEECCCCEEEECCCCCCCEEEEEEEECCCCCCEEEEEEEEEEEEECCCC
ARGAALTEGSIQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
RVMDPGDTDLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAAS
CCCCCCCHHHHHHHHHCCHHCCCCCCCEEEECCCCCCCCCEEEEEEHHHCCHHHHHHHHH
FQETTRVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPV
HHHHHHHHHHHHHCCCCHHCCCCCCCEEEEEEECCCCCHHHHCCCCCCCCCHHHHCCCCC
EEEGNEETTEVVVDTAVETVEETVE
CCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPEREGLFDEVIFGPTKDWEC
CCCCCCCCCEEEEECCCHHHCCCCCCCCCCCCCCCEEECCCHHHCCHHHHHCCCCCCCCH
ACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVSHIWYFKGIPSRMGLTLDM
HCCCHHEEEEECEEECCCCCHHHHHHHHHHHCCCEEEECCHHHEEEECCCCHHHCEEEEC
SPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLREYGYGSFVAKMGAEAIQDLL
CHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
KQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFYKSGNKPEWMILNILPVIPPDLR
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCC
PMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELNAPGIIVQNEKRMLQEAVDALIDNG
HHHEECCCCCCCCCHHHHHHHHHCCCCCEEHHEEECCCCEEEECHHHHHHHHHHHHHHCC
RRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLGKRVDFSGRSVIAVGPTLKMYQCGVPR
CCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCEEEEECCCEEEHCCCCCH
EMAIELFKPFVMREIVARDIVQNVKAAKRLVERGDERIWDILEEVIKEHPVLLNRAPTLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEECCCCCHH
RLGIQAFEPVLIDGKALRLHPLVCEAYNADFDGDQMAIHVPLSEEAQAEARILMLAAEHI
HHCHHHCCCEEECCCEEEEEHEEHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHEEHHHH
LNPKDGKPVVTPSQDMVLGNYYLTMEEAGREGEGMVFKDRDEAVMAYRNGYVHLHSRVGI
CCCCCCCEEECCCCCEEEEEEEEEEHHCCCCCCCCEEECCCCEEEEEECCEEEEECCCCE
ATDSLNKPWTEEQRHKVLLTTVGKILFNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGG
EECCCCCCCCHHHHHEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCH
AIKEAISNLELNPPFKKKNLGNIIAEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGI
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHEECC
ADIPVVDDKAEIIEESHKRVEQITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
DPKNPIVMMMDSGARGNISNFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFST
CCCCCEEEEECCCCCCCCHHHHHHHCCCCCEECCCCCEEEEHHHHHHHHHHHHHHHHHHH
HGARKGMTDTALKTADSGYLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLE
CCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHH
ERLNGRYTKKTVKHPETGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCR
HHHCCCCHHHHCCCCCCCEEEECCHHHHCCHHHHHHHHCCHHHEEEHHEEEECCCCCHHH
HCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEI
HHCCCEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHCCHHHHHH
FEARNPKGEAVITEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQV
HHCCCCCCCEEEEECCCCEEEECCCCCCCEEEEEEEECCCCCCEEEEEEEEEEEEECCCC
ARGAALTEGSIQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
RVMDPGDTDLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAAS
CCCCCCCHHHHHHHHHCCHHCCCCCCCEEEECCCCCCCCCEEEEEEHHHCCHHHHHHHHH
FQETTRVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPV
HHHHHHHHHHHHHCCCCHHCCCCCCCEEEEEEECCCCCHHHHCCCCCCCCCHHHHCCCCC
EEEGNEETTEVVVDTAVETVEETVE
CCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA