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The map label for this gene is rpoB

Identifier: 116516435

GI number: 116516435

Start: 1755553

End: 1759164

Strand: Reverse

Name: rpoB

Synonym: SPD_1759

Alternate gene names: 116516435

Gene position: 1759164-1755553 (Counterclockwise)

Preceding gene: 116515537

Following gene: 116515724

Centisome position: 85.98

GC content: 44.6

Gene sequence:

>3612_bases
TTGGCAGGACATGACGTTCAATACGGGAAACATCGTACCCGTCGTAGTTTTTCAAGAATCAAAGAAGTTCTTGACTTACC
AAATTTGATTGAAATTCAAACTGACTCATTCAAAGCTTTCCTAGACCACGGTCTTAAGGAAGTGTTTGAAGATGTATTGC
CAATTTCAAACTTCACAGACACAATGGAGTTGGAATTTGTTGGATATGAAATCAAGGAACCAAAATACACGCTAGAAGAA
GCTCGTATCCACGATGCTAGCTACTCAGCACCAATTTTTGTAACCTTCCGTTTGATCAATAAAGAAACAGGCGAAATCAA
GACCCAAGAAGTTTTCTTTGGTGATTTCCCAATCATGACAGAAATGGGTACTTTCATCATCAATGGTGGTGAACGTATTA
TCGTTTCTCAGTTGGTCCGCTCACCAGGTGTTTACTTTAACGACAAAGTAGACAAAAATGGTAAGGTGGGCTATGGTTCA
ACTGTTATCCCTAACCGTGGAGCTTGGTTGGAACTTGAAAGCGACTCAAAAGATATCACCTACACTCGTATCGACCGTAC
TCGTAAGATTCCATTTACAACCTTGGTTCGTGCTCTTGGTTTCTCAGGTGATGATGAAATCTTTGATATCTTTGGTGACA
GCGAATTGGTTCGCAACACTGTTGAAAAAGATATCCACAAGAATCCAATGGACTCTCGTACAGACGAAGCCTTGAAAGAA
ATTTACGAACGCCTTCGTCCAGGTGAGCCTAAGACAGCTGAAAGCTCACGTAGCTTGCTTGTGGCTCGCTTCTTTGACCC
ACGTCGCTATGACTTGGCAGCAGTTGGTCGTTACAAAATCAATAAAAAACTCAATGTTAAAACACGTTTGCTCAACCAAA
CCATTGCAGAGCCATTGGTAGACCCTGAAACTGGAGAAATCTTGGTAGAAGCTGGTACGATTATGACTCGTAGCGTGATT
GAAAGCATTGAAAGCCATTTGGATGGCGACTTGAACAAGATTGTCTACATCCCAAACGATGCAGCCGTTGTGACTGAGCC
TGTTGTTCTTCAAAAATTCAAGGTTGTTGCTCCAACTGATCCAGATCGCGTCGTAACGATCATTGGTAATGCTAACCCAG
ATGACAAGGTTCGTACGGTGACTCCTGCAGATATCCTTGCTGAGATGAGCTACTTCCTCAACTTGGCTGAAGGACTTGGC
CGTGTAGATGATATCGACCACCTTGGAAATCGTCGTATCCGTGCGGTTGGTGAATTGCTTGCCAACCAAGTACGTTTGGG
ACTTTCTCGTATGGAACGTAATGTCCGTGAACGTATGTCTGTTCAGGACAATGAAGTCTTGACACCACAACAAATTATCA
ATATCCGTCCTGTAACAGCTGCAGTTAAAGAATTCTTTGGTTCATCACAGTTGTCACAGTTCATGGACCAACACAACCCG
CTTTCTGAGTTGTCTCACAAACGCCGTTTGTCAGCCTTAGGACCTGGTGGTTTGACTCGTGACCGTGCCGGATATGAAGT
GCGTGACGTGCACTACACTCACTATGGTCGTATGTGTCCAATCGAAACACCTGAAGGACCTAACATCGGTTTGATCAATA
ACTTGTCATCTTACGGACACTTGAACAAATATGGTTTTGTTCAAACACCATACCGTAAGGTTGACCGTGAAACAGGTGTT
GTCACGAACGAAATTGTTTGGTTGACAGCTGATGAAGAAGATGAATATACTGTAGCTCAGGCTAACTCTCGTCTGAATGA
AGATGGAACCTTTGCTGAGAAGATTGTCATGGGACGTCACCAAGGGGTCAACCAAGAGTATCCAGCTAATATTGTTGACT
ACATGGACGTTTCACCAAAACAGGTAGTTGCCGTTGCGACAGCATGTATTCCTTTCTTGGAAAACGATGACTCCAACCGT
GCCCTCATGGGAGCCAATATGCAACGTCAGGCTGTGCCATTGATTAATCCTCAGGCACCTTACGTTGGTACTGGTATGGA
ATACCAAGCAGCCCACGATTCTGGTGCGGCTGTGATTGCTCAGTATGATGGTAAAGTTACTTACGCAGATGCTGACAAGG
TAGAAGTTCGTCGTGAAGATGGTTCATTGGATGTTTACCACATCCAAAAATTCCGTCGTTCAAACTCAGGTACTGCTTAC
AACCAACGCACTCTCGTAAAAGTTGGTGATGTCGTTGAAAAAGGCGATTTCATCGCTGACGGACCTTCTATGGAAAATGG
AGAAATGGCGCTTGGACAAAACCCAATCGTTGCCTACATGACTTGGGAAGGTTACAACTTCGAGGATGCCGTTATCATGA
GCGAACGCTTGGTGAAGGACGATGTCTACACATCTGTTCACCTTGAAGAATACGAATCAGAAACGCGCGATACAAAGCTT
GGGCCTGAAGAAATCACTCGCGAAATTCCAAACGTTGGTGAAGATGCCCTCAAAGACCTTGACGAAATGGGGATTATCCG
TATTGGTGCTGAGGTTAAAGAAGGTGATATTCTTGTAGGTAAAGTAACACCTAAGGGTGAGAAAGATCTTTCAGCTGAAG
AACGTCTCTTGCACGCTATCTTTGGAGACAAGTCTCGTGAAGTGCGTGATACTTCTCTTCGTGTACCACACGGTGCCGAT
GGTGTCGTTCGTGATGTTAAGATCTTTACACGTGTAAATGGAGATGAGTTGCAATCAGGTGTTAACATGTTGGTTCGTGT
TTACATCGCTCAAAAACGTAAGATTAAGGTCGGAGATAAAATGGCCGGACGTCACGGAAACAAAGGGGTTGTCTCTCGTA
TCGTTCCTGTAGAAGACATGCCTTACCTTCCAGACGGAACTCCAGTCGACATCATGTTGAACCCACTTGGGGTGCCATCA
CGTATGAATATCGGTCAGGTTATGGAGCTTCACCTTGGTATGGCAGCTCGTACTCTTGGTATTCACATTGCGACACCAGT
CTTTGATGGAGCAAGTTCTGAAGATCTTTGGTCAACTGTTAAAGAAGCAGGTATGGATAGCGATGCCAAGACAATCCTTT
ACGATGGACGTACAGGTGAACCATTTGATAACCGTGTTTCTGTTGGAGTCATGTACATGATCAAACTCCACCACATGGTT
GACGATAAATTGCACGCGCGTTCAGTCGGACCTTACTCAACTGTTACCCAACAACCACTCGGAGGTAAAGCTCAGTTTGG
TGGACAACGTTTCGGTGAGATGGAGGTTTGGGCTCTTGAAGCCTACGGTGCGTCAAATGTCCTTCAAGAAATCTTGACTT
ACAAGTCGGACGATATCAACGGACGTTTGAAAGCCTATGAAGCTATTACAAAAGGCAAACCAATTCCAAAACCAGGTGTT
CCAGAATCCTTCCGAGTTCTTGTCAAAGAATTGCAATCTCTTGGTCTTGACATGCGTGTCCTAGACGAAGATGACCAAGA
AGTGGAACTTCGCGACTTGGATGAAGGAATGGACGAAGATGTCATCCACGTAGATGACCTTGAAAAAGCCCGCGAAAAAG
CAGCCCAAGAGGCTAAAGCAGCCTTTGAAGCTGAAGAAGCTGAGAAAGCAACAAAAGCGGAAGCAACAGAAGAAGCTGCT
GAACAAGAATAA

Upstream 100 bases:

>100_bases
ATTCGTCAAGAGGACACGGTGATAAGGGGTTTACAACCATATGACGATTAGAAAAGCCTGATTGACAAGGCTTGGAACTT
ATTTACAAAGGAGAATCATC

Downstream 100 bases:

>100_bases
GCAGTTCACTTAGAATAGAAAGGGAAGAAATAGTGGTTGATGTAAATCGTTTTAAAAGTATGCAAATCACCCTAGCTTCT
CCAAGTAAAGTCCGTTCATG

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta

Number of amino acids: Translated: 1203; Mature: 1202

Protein sequence:

>1203_residues
MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHGLKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEE
ARIHDASYSAPIFVTFRLINKETGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVRNTVEKDIHKNPMDSRTDEALKE
IYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVGRYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVI
ESIESHLDGDLNKIVYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYFLNLAEGLG
RVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQQIINIRPVTAAVKEFFGSSQLSQFMDQHNP
LSELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGV
VTNEIVWLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVAVATACIPFLENDDSNR
ALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQYDGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAY
NQRTLVKVGDVVEKGDFIADGPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDTKL
GPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERLLHAIFGDKSREVRDTSLRVPHGAD
GVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRKIKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPS
RMNIGQVMELHLGMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGVMYMIKLHHMV
DDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVLQEILTYKSDDINGRLKAYEAITKGKPIPKPGV
PESFRVLVKELQSLGLDMRVLDEDDQEVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAA
EQE

Sequences:

>Translated_1203_residues
MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHGLKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEE
ARIHDASYSAPIFVTFRLINKETGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVRNTVEKDIHKNPMDSRTDEALKE
IYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVGRYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVI
ESIESHLDGDLNKIVYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYFLNLAEGLG
RVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQQIINIRPVTAAVKEFFGSSQLSQFMDQHNP
LSELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGV
VTNEIVWLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVAVATACIPFLENDDSNR
ALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQYDGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAY
NQRTLVKVGDVVEKGDFIADGPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDTKL
GPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERLLHAIFGDKSREVRDTSLRVPHGAD
GVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRKIKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPS
RMNIGQVMELHLGMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGVMYMIKLHHMV
DDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVLQEILTYKSDDINGRLKAYEAITKGKPIPKPGV
PESFRVLVKELQSLGLDMRVLDEDDQEVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAA
EQE
>Mature_1202_residues
AGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHGLKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEA
RIHDASYSAPIFVTFRLINKETGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGST
VIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVRNTVEKDIHKNPMDSRTDEALKEI
YERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVGRYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIE
SIESHLDGDLNKIVYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYFLNLAEGLGR
VDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQQIINIRPVTAAVKEFFGSSQLSQFMDQHNPL
SELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVV
TNEIVWLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVAVATACIPFLENDDSNRA
LMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQYDGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYN
QRTLVKVGDVVEKGDFIADGPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDTKLG
PEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERLLHAIFGDKSREVRDTSLRVPHGADG
VVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRKIKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSR
MNIGQVMELHLGMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGVMYMIKLHHMVD
DKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVLQEILTYKSDDINGRLKAYEAITKGKPIPKPGVP
ESFRVLVKELQSLGLDMRVLDEDDQEVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAE
QE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family

Homologues:

Organism=Homo sapiens, GI238908503, Length=816, Percent_Identity=26.1029411764706, Blast_Score=204, Evalue=6e-52,
Organism=Homo sapiens, GI238908505, Length=816, Percent_Identity=26.1029411764706, Blast_Score=203, Evalue=1e-51,
Organism=Homo sapiens, GI4505941, Length=418, Percent_Identity=30.3827751196172, Blast_Score=176, Evalue=8e-44,
Organism=Homo sapiens, GI33469941, Length=352, Percent_Identity=33.2386363636364, Blast_Score=162, Evalue=2e-39,
Organism=Homo sapiens, GI212286172, Length=352, Percent_Identity=33.2386363636364, Blast_Score=162, Evalue=2e-39,
Organism=Escherichia coli, GI1790419, Length=964, Percent_Identity=45.0207468879668, Blast_Score=795, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17552304, Length=418, Percent_Identity=31.5789473684211, Blast_Score=181, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI25144348, Length=443, Percent_Identity=30.6997742663657, Blast_Score=180, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17506623, Length=185, Percent_Identity=40, Blast_Score=129, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6324725, Length=356, Percent_Identity=31.7415730337079, Blast_Score=175, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6324781, Length=414, Percent_Identity=30.4347826086957, Blast_Score=171, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6325267, Length=365, Percent_Identity=32.6027397260274, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI17647877, Length=424, Percent_Identity=30.188679245283, Blast_Score=174, Evalue=4e-43,
Organism=Drosophila melanogaster, GI17136444, Length=417, Percent_Identity=30.2158273381295, Blast_Score=169, Evalue=1e-41,
Organism=Drosophila melanogaster, GI17136446, Length=434, Percent_Identity=27.4193548387097, Blast_Score=123, Evalue=9e-28,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): RPOB_STRP2 (Q04IK6)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_817182.1
- ProteinModelPortal:   Q04IK6
- SMR:   Q04IK6
- STRING:   Q04IK6
- PhosSite:   Q04IK6
- EnsemblBacteria:   EBSTRT00000019184
- GeneID:   4441661
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_1759
- eggNOG:   COG0085
- GeneTree:   EBGT00050000027106
- HOGENOM:   HBG285547
- OMA:   FMTWEGY
- ProtClustDB:   PRK00405
- HAMAP:   MF_01321
- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- Gene3D:   G3DSA:2.40.50.150
- PANTHER:   PTHR20856
- TIGRFAMs:   TIGR02013

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7

EC number: =2.7.7.6

Molecular weight: Translated: 134319; Mature: 134188

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHGLKEVFEDVLPISNFTD
CCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCC
TMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKETGEIKTQEVFFGDFPIMT
CEEEEEEEEEECCCCHHHHHHHCCCCCCCCCEEEEEEEECCCCCCEEEEEEEECCCCHHH
EMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGSTVIPNRGAWLELESDSKDIT
CCCCEEECCCCHHHHHHHHHCCCCEECCCCCCCCCCCCCCEECCCCCCEEEECCCCCCEE
YTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVRNTVEKDIHKNPMDSRTDEALKE
EEECCCCCCCCHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCHHHHHHHH
IYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVGRYKINKKLNVKTRLLNQTIAEPLV
HHHHHCCCCCCCCCCCCCEEEEEECCCCCCCEEEECEEEECCCCCHHHHHHHHHHHHHCC
DPETGEILVEAGTIMTRSVIESIESHLDGDLNKIVYIPNDAAVVTEPVVLQKFKVVAPTD
CCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEECCHHHHEEEEECCCC
PDRVVTIIGNANPDDKVRTVTPADILAEMSYFLNLAEGLGRVDDIDHLGNRRIRAVGELL
CCCEEEEEECCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHH
ANQVRLGLSRMERNVRERMSVQDNEVLTPQQIINIRPVTAAVKEFFGSSQLSQFMDQHNP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHCHHHHHHHHHCCCC
LSELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSYGH
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEECCCHHCCC
LNKYGFVQTPYRKVDRETGVVTNEIVWLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRH
CCCCCCCCCCHHHHHHHCCCEEEEEEEEEECCCCCEEHHHHHCCCCCCCHHHHHHHHHHC
QGVNQEYPANIVDYMDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQAVPLINPQAP
CCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCC
YVGTGMEYQAAHDSGAAVIAQYDGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAY
CCCCCCEEECCCCCCCEEEEEECCEEEEECCCCEEEEECCCCEEHHHHHHHHHCCCCCCC
NQRTLVKVGDVVEKGDFIADGPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKD
CCEEEEEHHHHHHCCCEEECCCCCCCCCEEECCCCEEEEEEECCCCCCHHHHHHHHHHHH
DVYTSVHLEEYESETRDTKLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVG
HHHHEEEHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHCCEEEECCEECCCCEEEE
KVTPKGEKDLSAEERLLHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSG
ECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHEEEEEECCHHHHHHH
VNMLVRVYIAQKRKIKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPS
HHHHHHHHHHHCCEEECCCHHCCCCCCCCHHHEECCCCCCCCCCCCCCEEEEECCCCCCC
RMNIGQVMELHLGMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGE
CCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCC
PFDNRVSVGVMYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALE
CCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEEEEE
AYGASNVLQEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRV
CCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEE
LDEDDQEVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAA
ECCCCCCCHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQE
CCC
>Mature Secondary Structure 
AGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHGLKEVFEDVLPISNFTD
CCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCC
TMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKETGEIKTQEVFFGDFPIMT
CEEEEEEEEEECCCCHHHHHHHCCCCCCCCCEEEEEEEECCCCCCEEEEEEEECCCCHHH
EMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGSTVIPNRGAWLELESDSKDIT
CCCCEEECCCCHHHHHHHHHCCCCEECCCCCCCCCCCCCCEECCCCCCEEEECCCCCCEE
YTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVRNTVEKDIHKNPMDSRTDEALKE
EEECCCCCCCCHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCHHHHHHHH
IYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVGRYKINKKLNVKTRLLNQTIAEPLV
HHHHHCCCCCCCCCCCCCEEEEEECCCCCCCEEEECEEEECCCCCHHHHHHHHHHHHHCC
DPETGEILVEAGTIMTRSVIESIESHLDGDLNKIVYIPNDAAVVTEPVVLQKFKVVAPTD
CCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEECCHHHHEEEEECCCC
PDRVVTIIGNANPDDKVRTVTPADILAEMSYFLNLAEGLGRVDDIDHLGNRRIRAVGELL
CCCEEEEEECCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHH
ANQVRLGLSRMERNVRERMSVQDNEVLTPQQIINIRPVTAAVKEFFGSSQLSQFMDQHNP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHCHHHHHHHHHCCCC
LSELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSYGH
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEECCCHHCCC
LNKYGFVQTPYRKVDRETGVVTNEIVWLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRH
CCCCCCCCCCHHHHHHHCCCEEEEEEEEEECCCCCEEHHHHHCCCCCCCHHHHHHHHHHC
QGVNQEYPANIVDYMDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQAVPLINPQAP
CCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCC
YVGTGMEYQAAHDSGAAVIAQYDGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAY
CCCCCCEEECCCCCCCEEEEEECCEEEEECCCCEEEEECCCCEEHHHHHHHHHCCCCCCC
NQRTLVKVGDVVEKGDFIADGPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKD
CCEEEEEHHHHHHCCCEEECCCCCCCCCEEECCCCEEEEEEECCCCCCHHHHHHHHHHHH
DVYTSVHLEEYESETRDTKLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVG
HHHHEEEHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHCCEEEECCEECCCCEEEE
KVTPKGEKDLSAEERLLHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSG
ECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHEEEEEECCHHHHHHH
VNMLVRVYIAQKRKIKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPS
HHHHHHHHHHHCCEEECCCHHCCCCCCCCHHHEECCCCCCCCCCCCCCEEEEECCCCCCC
RMNIGQVMELHLGMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGE
CCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCC
PFDNRVSVGVMYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALE
CCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEEEEE
AYGASNVLQEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRV
CCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEE
LDEDDQEVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAA
ECCCCCCCHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQE
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA