Click here to switch to the map view.

The map label for this gene is accA

Identifier: 116515640

GI number: 116515640

Start: 393075

End: 393842

Strand: Direct

Name: accA

Synonym: SPD_0390

Alternate gene names: 116515640

Gene position: 393075-393842 (Clockwise)

Preceding gene: 116515562

Following gene: 116515989

Centisome position: 19.21

GC content: 45.31

Gene sequence:

>768_bases
ATGAATATTGCAAAAATAGTCAGAGAAGCGCGTGAGCAGAGTCGCTTGACAACCTTGGACTTTGCGACAGGCATTTTTGA
TGAATTTATCCAATTACATGGTGACCGTTCTTTTCGTGATGATGGTGCAGTTGTTGGTGGTATTGGTTGGCTTGGAGACC
AAGCTGTAACAGTGGTTGGTATCCAAAAAGGCAAGAGTTTGCAAGACAACCTCAAACGGAATTTTGGCCAACCACATCCA
GAAGGCTACCGAAAGGCACTGCGGTTGATGAAACAGGCTGAGAAATTTGGCCGTCCAGTTGTGACCTTTATCAATACAGC
AGGTGCTTATCCTGGTGTCGGAGCGGAAGAACGTGGTCAAGGGGAAGCTATCGCTCGCAATCTCATGGAAATGAGTGACC
TGAAAGTTCCTATTATCGCCATTATTATCGGTGAAGGTGGTTCAGGCGGGGCTCTGGCTCTAGCTGTCGCGGACCGTGTC
TGGATGCTGGAAAATTCTATCTATGCCATTCTCAGTCCAGAAGGCTTTGCTTCCATTTTATGGAAGGACGGTACTCGCGC
CATGGAAGCAGCAGAACTGATGAAAATCACTTCGCATGAACTGTTAGAAATGGACGTGGTGGATAAGGTGATTTCTGAAG
TAGGACTTTCTAGTAAAGAACTAATTAAGAGTGTCAAAAAAGAACTCCAAACGGAGCTGGCTAGACTTTCACAAAAACCG
CTAGAAGAGTTGCTGGAAGAACGCTATCAACGATTTAGAAAATACTAA

Upstream 100 bases:

>100_bases
AATTCCTATTAGAACATGGCTTTGTGGATGCTATTGTCAAAAGAAGAGACTTACCAGATACGATTGCTAGCCTAGTCAGA
TTGCATGGAGGGAGTCCTAG

Downstream 100 bases:

>100_bases
GAATGACTAAATGAGACTAGAAAGGTCTCATTTTTTATGGAAAAATGCAATTCAGGTCGAAAAATTGCCAGTTGAGGAGA
TAGACTATAAAATAGACAAA

Product: acetyl-CoA carboxylase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAVVGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHP
EGYRKALRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSSKELIKSVKKELQTELARLSQKP
LEELLEERYQRFRKY

Sequences:

>Translated_255_residues
MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAVVGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHP
EGYRKALRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSSKELIKSVKKELQTELARLSQKP
LEELLEERYQRFRKY
>Mature_255_residues
MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAVVGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHP
EGYRKALRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSSKELIKSVKKELQTELARLSQKP
LEELLEERYQRFRKY

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=255, Percent_Identity=50.9803921568627, Blast_Score=256, Evalue=1e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_STRP2 (Q04M48)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_815900.1
- ProteinModelPortal:   Q04M48
- SMR:   Q04M48
- STRING:   Q04M48
- EnsemblBacteria:   EBSTRT00000020235
- GeneID:   4441320
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_0390
- eggNOG:   COG0825
- GeneTree:   EBGT00050000028355
- HOGENOM:   HBG286557
- OMA:   GSPEPWG
- ProtClustDB:   PRK12319
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 28234; Mature: 28234

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAVVGGIGWLGDQAVTVVG
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECHHHCCCCEEEEEE
IQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQ
ECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCC
GEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRVWMLENSIYAILSPEGFASIL
HHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEHHHHHHHHHHHHCCEEEEECCCCHHHHH
WKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSSKELIKSVKKELQTELARLSQKP
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LEELLEERYQRFRKY
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAVVGGIGWLGDQAVTVVG
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECHHHCCCCEEEEEE
IQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQ
ECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCC
GEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRVWMLENSIYAILSPEGFASIL
HHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEHHHHHHHHHHHHCCEEEEECCCCHHHHH
WKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSSKELIKSVKKELQTELARLSQKP
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LEELLEERYQRFRKY
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA