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The map label for this gene is accD

Identifier: 116515562

GI number: 116515562

Start: 392212

End: 393078

Strand: Direct

Name: accD

Synonym: SPD_0389

Alternate gene names: 116515562

Gene position: 392212-393078 (Clockwise)

Preceding gene: 116515928

Following gene: 116515640

Centisome position: 19.17

GC content: 43.83

Gene sequence:

>867_bases
ATGGCTCTATTTAGTAAAAAAGATAAGTATATTCGAATCAATCCCAATCGTTCGGTTAGGGAAAAACCTCAAGCTAAGCC
AGAGGTTCCAGATGAATTATTTTCCCAGTGTCCAGGCTGTAAGCATACCATCTATCAGAAGGATCTGGGAAGTGAACGTA
TCTGTCCGCACTGTAGCTATACCTTTCGTATTTCTGCCCAAGAACGCTTGGCTTTGACGATTGATATGGGAACCTTCAAA
GAATTGTTTACAGGGATTGAAAGCAAGGATCCCTTGCATTTCCCTGGTTACCAAAAGAAACTGGCATCTATGCGTGAAAA
AACAGGTCTGCATGAAGCCGTTGTGACAGGAACTGCTCTTATTAAAGGTCAGACTGTGGCTCTTGGGATTATGGATTCTA
ATTTTATCATGGCTTCTATGGGTACGGTTGTAGGTGAAAAAATCACTCGTTTGTTTGAGTATGCGACTGTCGAAAAATTG
CCAGTTGTCCTATTCACAGCCTCTGGTGGAGCCCGTATGCAGGAAGGAATCATGAGTCTCATGCAGATGGCTAAGATCTC
TGCAGCGGTTAAACGCCATTCAAATGCTGGTCTCTTTTACCTGACCATTTTGACAGATCCAACGACTGGTGGTGTGACAG
CTTCTTTCGCTATGGAAGGCGATATCATTCTGGCTGAACCACAGAGCTTGGTTGGTTTTGCTGGGCGTCGTGTGATTGAA
AATACGGTTCGTGAAAGCTTGCCTGAGGATTTCCAAAAGGCAGAATTCCTATTAGAACATGGCTTTGTGGATGCTATTGT
CAAAAGAAGAGACTTACCAGATACGATTGCTAGCCTAGTCAGATTGCATGGAGGGAGTCCTAGATGA

Upstream 100 bases:

>100_bases
TGGGGATTATGATACTTCCTTCTTGATGGAAACCTTCTTACCTAAATATCAAGAAAAAGAATAAAATGACTTTAAGAGTT
TAAACCGAAAAGGGGAATCA

Downstream 100 bases:

>100_bases
ATATTGCAAAAATAGTCAGAGAAGCGCGTGAGCAGAGTCGCTTGACAACCTTGGACTTTGCGACAGGCATTTTTGATGAA
TTTATCCAATTACATGGTGA

Product: acetyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTIYQKDLGSERICPHCSYTFRISAQERLALTIDMGTFK
ELFTGIESKDPLHFPGYQKKLASMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAMEGDIILAEPQSLVGFAGRRVIE
NTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTIASLVRLHGGSPR

Sequences:

>Translated_288_residues
MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTIYQKDLGSERICPHCSYTFRISAQERLALTIDMGTFK
ELFTGIESKDPLHFPGYQKKLASMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAMEGDIILAEPQSLVGFAGRRVIE
NTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTIASLVRLHGGSPR
>Mature_287_residues
ALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTIYQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKE
LFTGIESKDPLHFPGYQKKLASMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKLP
VVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAMEGDIILAEPQSLVGFAGRRVIEN
TVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTIASLVRLHGGSPR

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Escherichia coli, GI1788655, Length=262, Percent_Identity=43.5114503816794, Blast_Score=226, Evalue=1e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_STRPN (P0CC08)

Other databases:

- EMBL:   AE005672
- PIR:   B97920
- PIR:   D95049
- RefSeq:   NP_344949.1
- ProteinModelPortal:   P0CC08
- SMR:   P0CC08
- EnsemblBacteria:   EBSTRT00000026838
- GeneID:   930362
- GenomeReviews:   AE005672_GR
- KEGG:   spn:SP_0426
- TIGR:   SP_0426
- GeneTree:   EBGT00050000027254
- OMA:   LEHGMVD
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 31786; Mature: 31655

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTIYQKDLGSERICPHCSY
CCCCCCCCCEEEECCCCCHHCCCCCCCCCCHHHHHHCCCCCHHHHHHHCCCCCCCCCCCE
TFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLASMREKTGLHEAVVTGTAL
EEEECCCCEEEEEEECHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHE
IKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKLPVVLFTASGGARMQEGIMSL
ECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHH
MQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAMEGDIILAEPQSLVGFAGRRVIE
HHHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEEEEECCCEEEECCHHHHHHHHHHHHH
NTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTIASLVRLHGGSPR
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTIYQKDLGSERICPHCSY
CCCCCCCCEEEECCCCCHHCCCCCCCCCCHHHHHHCCCCCHHHHHHHCCCCCCCCCCCE
TFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLASMREKTGLHEAVVTGTAL
EEEECCCCEEEEEEECHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHE
IKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKLPVVLFTASGGARMQEGIMSL
ECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHH
MQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAMEGDIILAEPQSLVGFAGRRVIE
HHHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEEEEECCCEEEECCHHHHHHHHHHHHH
NTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTIASLVRLHGGSPR
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916