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The map label for this gene is nrnA [H]

Identifier: 116494325

GI number: 116494325

Start: 777312

End: 778268

Strand: Direct

Name: nrnA [H]

Synonym: LSEI_0781

Alternate gene names: 116494325

Gene position: 777312-778268 (Clockwise)

Preceding gene: 116494324

Following gene: 116494326

Centisome position: 26.85

GC content: 48.59

Gene sequence:

>957_bases
ATGATTCAAACCGATATTATTAACGCCATCAAGGCAAACGATCCAATCATTATCCATCGTCATGTGAACCCAGATCCAGA
TGCGTTGGGTTCCCAAGTTGGCTTAGCAGAAACCATTCGCGCTAGTTTTCCGGATAAGAAAGTGTATCAGGTTGGTAGTG
ACACTGGCAATTTGAGCTGGTTGGCACAGGAACAAACCATTACGGATGACGTTTACAAGGATGCTCTCGTGATTGTGACC
GATACTGCCGATACGCCGCGAGTTTCTGATGAGCGCTTCAACAAGGGGAAAATGCTGATCAAAATCGATCATCATCCGAA
CGATGATGCGTATGGCGATCTCGTTTGGGTCGATAACAACGCTAGCTCTGCCTCTGAACTGATTTACGATTTAATCGCCG
CCAGCAACGGTGTTTTGAAACTCAGCGATAAGGCTGCTCGCCTAATGTACGCTGGGATCGTTGGCGACACCGGCCGATTT
TTATTTAACAATACGACCCCGCATACGTTGCAGGTCGCGGCTGAGTTGATTAAAAAGGATTTTGATCCAACAGCCATTAA
TAATCGGATGAACACGGTGACGTTGGCACAAGCACGGTTGCAAGGCTATGTTGTCGATCATCTGAAAATTACCCCAGCAG
GTGCCGCCAGTGTGACGGTACCACGGACCGCGATCAACGAGCTGAAACTGGCTGATGATCAGGTAAGCGCTGTTGTCGGC
ACACCCGGCCGACTGGATACCGTCATTGCTTGGGCAGAATTTATTGAACAGGCAGAAGGCGGTTACCGCGTTCATCTGCG
TTCAAAAGGTCCCATCATCAACACACTTGCCAAAGCACACAATGGCGGTGGTCATCCATTAGCAAGCGGCGCTAAGGCAG
CTAATTTTGACGAACTGATTCAAATCGAGACGCAACTCGATCAACTGGTCAAAGAATATTCGACCTCAGGAAAGTAG

Upstream 100 bases:

>100_bases
TAGGCATGATGCGACGCTGGATGTTGATGTCTTAAGCGACGGGGTTCAGGTTGCTAAAGCGATTGTGACCTGCCAGCTAT
TAGAAAGGAATTGATTTTTG

Downstream 100 bases:

>100_bases
GCATTATGGAGAATCAATTCAAACAATTTCAACTAAAACCTTTTGTTATCGATGGTCTCAATGCAATGGCCATCACCGCC
CCGACACCCATTCAACAAAA

Product: phosphoesterase, DHH family protein

Products: NA

Alternate protein names: 3'(2'),5'-bisphosphate nucleotidase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; nanoRNAse [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MIQTDIINAIKANDPIIIHRHVNPDPDALGSQVGLAETIRASFPDKKVYQVGSDTGNLSWLAQEQTITDDVYKDALVIVT
DTADTPRVSDERFNKGKMLIKIDHHPNDDAYGDLVWVDNNASSASELIYDLIAASNGVLKLSDKAARLMYAGIVGDTGRF
LFNNTTPHTLQVAAELIKKDFDPTAINNRMNTVTLAQARLQGYVVDHLKITPAGAASVTVPRTAINELKLADDQVSAVVG
TPGRLDTVIAWAEFIEQAEGGYRVHLRSKGPIINTLAKAHNGGGHPLASGAKAANFDELIQIETQLDQLVKEYSTSGK

Sequences:

>Translated_318_residues
MIQTDIINAIKANDPIIIHRHVNPDPDALGSQVGLAETIRASFPDKKVYQVGSDTGNLSWLAQEQTITDDVYKDALVIVT
DTADTPRVSDERFNKGKMLIKIDHHPNDDAYGDLVWVDNNASSASELIYDLIAASNGVLKLSDKAARLMYAGIVGDTGRF
LFNNTTPHTLQVAAELIKKDFDPTAINNRMNTVTLAQARLQGYVVDHLKITPAGAASVTVPRTAINELKLADDQVSAVVG
TPGRLDTVIAWAEFIEQAEGGYRVHLRSKGPIINTLAKAHNGGGHPLASGAKAANFDELIQIETQLDQLVKEYSTSGK
>Mature_318_residues
MIQTDIINAIKANDPIIIHRHVNPDPDALGSQVGLAETIRASFPDKKVYQVGSDTGNLSWLAQEQTITDDVYKDALVIVT
DTADTPRVSDERFNKGKMLIKIDHHPNDDAYGDLVWVDNNASSASELIYDLIAASNGVLKLSDKAARLMYAGIVGDTGRF
LFNNTTPHTLQVAAELIKKDFDPTAINNRMNTVTLAQARLQGYVVDHLKITPAGAASVTVPRTAINELKLADDQVSAVVG
TPGRLDTVIAWAEFIEQAEGGYRVHLRSKGPIINTLAKAHNGGGHPLASGAKAANFDELIQIETQLDQLVKEYSTSGK

Specific function: Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA oligonucleotides with a length of 5 nucleotides and shorter. Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP [H]

COG id: COG0618

COG function: function code R; Exopolyphosphatase-related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003156
- InterPro:   IPR001667 [H]

Pfam domain/function: PF01368 DHH; PF02272 DHHA1 [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 34403; Mature: 34403

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQTDIINAIKANDPIIIHRHVNPDPDALGSQVGLAETIRASFPDKKVYQVGSDTGNLSW
CCCHHHHHHHCCCCCEEEEECCCCCHHHHCCCCCHHHHHHHCCCCCCEEEECCCCCCEEE
LAQEQTITDDVYKDALVIVTDTADTPRVSDERFNKGKMLIKIDHHPNDDAYGDLVWVDNN
EECCCCHHHHHHCCEEEEEECCCCCCCCCHHHCCCCCEEEEECCCCCCCCCCCEEEEECC
ASSASELIYDLIAASNGVLKLSDKAARLMYAGIVGDTGRFLFNNTTPHTLQVAAELIKKD
CCHHHHHHHHHHHCCCCEEEECCHHCEEEEEEEECCCCCEEECCCCCHHHHHHHHHHHCC
FDPTAINNRMNTVTLAQARLQGYVVDHLKITPAGAASVTVPRTAINELKLADDQVSAVVG
CCCCHHCCCCCEEEEHHHHHCCEEEEEEEECCCCCCEEEECHHHHHHHHCCCCHHHEEEC
TPGRLDTVIAWAEFIEQAEGGYRVHLRSKGPIINTLAKAHNGGGHPLASGAKAANFDELI
CCCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
QIETQLDQLVKEYSTSGK
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIQTDIINAIKANDPIIIHRHVNPDPDALGSQVGLAETIRASFPDKKVYQVGSDTGNLSW
CCCHHHHHHHCCCCCEEEEECCCCCHHHHCCCCCHHHHHHHCCCCCCEEEECCCCCCEEE
LAQEQTITDDVYKDALVIVTDTADTPRVSDERFNKGKMLIKIDHHPNDDAYGDLVWVDNN
EECCCCHHHHHHCCEEEEEECCCCCCCCCHHHCCCCCEEEEECCCCCCCCCCCEEEEECC
ASSASELIYDLIAASNGVLKLSDKAARLMYAGIVGDTGRFLFNNTTPHTLQVAAELIKKD
CCHHHHHHHHHHHCCCCEEEECCHHCEEEEEEEECCCCCEEECCCCCHHHHHHHHHHHCC
FDPTAINNRMNTVTLAQARLQGYVVDHLKITPAGAASVTVPRTAINELKLADDQVSAVVG
CCCCHHCCCCCEEEEHHHHHCCEEEEEEEECCCCCCEEEECHHHHHHHHCCCCHHHEEEC
TPGRLDTVIAWAEFIEQAEGGYRVHLRSKGPIINTLAKAHNGGGHPLASGAKAANFDELI
CCCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
QIETQLDQLVKEYSTSGK
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]