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The map label for this gene is galE [H]

Identifier: 116494213

GI number: 116494213

Start: 668402

End: 669397

Strand: Direct

Name: galE [H]

Synonym: LSEI_0665

Alternate gene names: 116494213

Gene position: 668402-669397 (Clockwise)

Preceding gene: 116494212

Following gene: 116494214

Centisome position: 23.09

GC content: 47.89

Gene sequence:

>996_bases
ATGACAATTGCAGTTTTAGGCGGCGCTGGTTACATCGGTTCACATACGGTAAAACAATTACTCGCTGCCGGCGAGGATGT
TGTGGTTTTGGATAACTTGATTACTGGGCATCGTAAGGCGGTTGATCCACGCGCCCGTTTTTATCAAGGCGACATCCGCG
ACTATCATTTTCTGAGCCAAGTGTTCAGCCAGGAAAAGATTGACGGGATTGTCCATTTTGCGGCGTTCTCAATTGTGCCG
GAATCCATGAAAGATCCGTTGAAGTATTTTGATAACAACACTGGCGGCATGATCACCTTGCTTGAAGCCATGAATCAATT
CGGCATCAAGAAAATTGTCTTCTCATCTACGGCAGCAACTTATGGCGAACCTAAGCAGGTCCCAATTAAAGAAACTGATC
CGCAAGTACCGACCAACCCATACGGTGAAAGCAAGTTGGCGATGGAAAAGATCATGCATTGGGCTGATGTGGCTTATGGG
CTGAAGTTCGTGGCTTTGCGTTACTTCAATGTTGCGGGTGCGATGCCAGACGGTTCCATCGGTGAAGACCATCATCCAGA
AACACATATTGTGCCAATCATCTTGCAGGTTGCAGCAGGTACACGAACTGGTTTGCAAATTTATGGTGACGACTATCCAA
CCAAGGATGGTACCAATGTGCGTGACTATGTTCATGTGGGCGATCTTGCTGATGCCCACATTTTGGCCTTGAAGTATCTG
GATGCCGGCAATAAGTCATCCGCGTTCAACATTGGTTCTGCGCATGGTTTCTCCAACCTTGAAATTCTAAATGCAGCGCG
TAAGGTGACTGGCCAAGAGATTCCAGCCACGATGGGCCCGCGGCGTGCCGGTGATCCAAGCACTTTGATTGCTAGCTCAG
AAAAGGCTCGTGACATTTTAGGCTGGAAGCCAAACTATGACGATATTGACAAGATTATCGAAACCGCATGGAACTGGCAC
GAAAATCACCCAGAAGGATTTGGTGACCGGAATTGA

Upstream 100 bases:

>100_bases
ACTAACTCTGCTAAAATAGAAAAAGTGTTATAAAGTAGAGCGTGAGCCAGACCGATTTCTAGTCTGACGAACACGTTTTA
AAAAAGGGAGATATTTTATT

Downstream 100 bases:

>100_bases
CCGCGATTAGCAATCACATTGATACCATCATTAAGCTCAATCCTGACTATACCCAGATGGATGCGGTCTACCTGACCAAC
AAATTGCTGAATCTGATCGG

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MTIAVLGGAGYIGSHTVKQLLAAGEDVVVLDNLITGHRKAVDPRARFYQGDIRDYHFLSQVFSQEKIDGIVHFAAFSIVP
ESMKDPLKYFDNNTGGMITLLEAMNQFGIKKIVFSSTAATYGEPKQVPIKETDPQVPTNPYGESKLAMEKIMHWADVAYG
LKFVALRYFNVAGAMPDGSIGEDHHPETHIVPIILQVAAGTRTGLQIYGDDYPTKDGTNVRDYVHVGDLADAHILALKYL
DAGNKSSAFNIGSAHGFSNLEILNAARKVTGQEIPATMGPRRAGDPSTLIASSEKARDILGWKPNYDDIDKIIETAWNWH
ENHPEGFGDRN

Sequences:

>Translated_331_residues
MTIAVLGGAGYIGSHTVKQLLAAGEDVVVLDNLITGHRKAVDPRARFYQGDIRDYHFLSQVFSQEKIDGIVHFAAFSIVP
ESMKDPLKYFDNNTGGMITLLEAMNQFGIKKIVFSSTAATYGEPKQVPIKETDPQVPTNPYGESKLAMEKIMHWADVAYG
LKFVALRYFNVAGAMPDGSIGEDHHPETHIVPIILQVAAGTRTGLQIYGDDYPTKDGTNVRDYVHVGDLADAHILALKYL
DAGNKSSAFNIGSAHGFSNLEILNAARKVTGQEIPATMGPRRAGDPSTLIASSEKARDILGWKPNYDDIDKIIETAWNWH
ENHPEGFGDRN
>Mature_330_residues
TIAVLGGAGYIGSHTVKQLLAAGEDVVVLDNLITGHRKAVDPRARFYQGDIRDYHFLSQVFSQEKIDGIVHFAAFSIVPE
SMKDPLKYFDNNTGGMITLLEAMNQFGIKKIVFSSTAATYGEPKQVPIKETDPQVPTNPYGESKLAMEKIMHWADVAYGL
KFVALRYFNVAGAMPDGSIGEDHHPETHIVPIILQVAAGTRTGLQIYGDDYPTKDGTNVRDYVHVGDLADAHILALKYLD
AGNKSSAFNIGSAHGFSNLEILNAARKVTGQEIPATMGPRRAGDPSTLIASSEKARDILGWKPNYDDIDKIIETAWNWHE
NHPEGFGDRN

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=348, Percent_Identity=38.7931034482759, Blast_Score=235, Evalue=4e-62,
Organism=Homo sapiens, GI56118217, Length=348, Percent_Identity=38.7931034482759, Blast_Score=235, Evalue=4e-62,
Organism=Homo sapiens, GI189083684, Length=348, Percent_Identity=38.7931034482759, Blast_Score=235, Evalue=4e-62,
Organism=Homo sapiens, GI42516563, Length=310, Percent_Identity=26.1290322580645, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI7657641, Length=332, Percent_Identity=27.710843373494, Blast_Score=96, Evalue=7e-20,
Organism=Escherichia coli, GI1786974, Length=341, Percent_Identity=39.8826979472141, Blast_Score=252, Evalue=2e-68,
Organism=Escherichia coli, GI1788353, Length=338, Percent_Identity=27.5147928994083, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI48994969, Length=334, Percent_Identity=28.4431137724551, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790049, Length=259, Percent_Identity=30.8880308880309, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71982035, Length=348, Percent_Identity=37.6436781609195, Blast_Score=221, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI71982038, Length=350, Percent_Identity=37.4285714285714, Blast_Score=220, Evalue=8e-58,
Organism=Caenorhabditis elegans, GI17539532, Length=328, Percent_Identity=26.219512195122, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17568069, Length=331, Percent_Identity=25.9818731117825, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115532424, Length=334, Percent_Identity=25.1497005988024, Blast_Score=81, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6319493, Length=351, Percent_Identity=41.025641025641, Blast_Score=248, Evalue=8e-67,
Organism=Saccharomyces cerevisiae, GI6321437, Length=264, Percent_Identity=24.6212121212121, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI19923002, Length=349, Percent_Identity=40.6876790830946, Blast_Score=249, Evalue=1e-66,
Organism=Drosophila melanogaster, GI21356223, Length=312, Percent_Identity=27.2435897435897, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36296; Mature: 36165

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIAVLGGAGYIGSHTVKQLLAAGEDVVVLDNLITGHRKAVDPRARFYQGDIRDYHFLSQ
CEEEEECCCCCCHHHHHHHHHHCCCCEEEEHHHHHCCHHHCCHHHHHHCCCCHHHHHHHH
VFSQEKIDGIVHFAAFSIVPESMKDPLKYFDNNTGGMITLLEAMNQFGIKKIVFSSTAAT
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEHHHHHHHHHCHHHHHHHCCHHC
YGEPKQVPIKETDPQVPTNPYGESKLAMEKIMHWADVAYGLKFVALRYFNVAGAMPDGSI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GEDHHPETHIVPIILQVAAGTRTGLQIYGDDYPTKDGTNVRDYVHVGDLADAHILALKYL
CCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHEEEECCCCCHHEEEEEEC
DAGNKSSAFNIGSAHGFSNLEILNAARKVTGQEIPATMGPRRAGDPSTLIASSEKARDIL
CCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCHHHHHHC
GWKPNYDDIDKIIETAWNWHENHPEGFGDRN
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TIAVLGGAGYIGSHTVKQLLAAGEDVVVLDNLITGHRKAVDPRARFYQGDIRDYHFLSQ
EEEEECCCCCCHHHHHHHHHHCCCCEEEEHHHHHCCHHHCCHHHHHHCCCCHHHHHHHH
VFSQEKIDGIVHFAAFSIVPESMKDPLKYFDNNTGGMITLLEAMNQFGIKKIVFSSTAAT
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEHHHHHHHHHCHHHHHHHCCHHC
YGEPKQVPIKETDPQVPTNPYGESKLAMEKIMHWADVAYGLKFVALRYFNVAGAMPDGSI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GEDHHPETHIVPIILQVAAGTRTGLQIYGDDYPTKDGTNVRDYVHVGDLADAHILALKYL
CCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHEEEECCCCCHHEEEEEEC
DAGNKSSAFNIGSAHGFSNLEILNAARKVTGQEIPATMGPRRAGDPSTLIASSEKARDIL
CCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCHHHHHHC
GWKPNYDDIDKIIETAWNWHENHPEGFGDRN
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9603808 [H]