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The map label for this gene is treA [H]

Identifier: 116494180

GI number: 116494180

Start: 624555

End: 626201

Strand: Direct

Name: treA [H]

Synonym: LSEI_0630

Alternate gene names: 116494180

Gene position: 624555-626201 (Clockwise)

Preceding gene: 116494179

Following gene: 116494181

Centisome position: 21.57

GC content: 45.72

Gene sequence:

>1647_bases
ATGGGATTTCATAATAAAGTCATTTATCAGCTGTACCCCAAGTCTTTTTATGATAGTGATGGCGATGGGGTTGGCGATCT
ACGCGGCATTATCGACAAGATCGATTACCTCAAGTCATTACATGTCGACATGATTTGGTTTAATCCATTTTTTGTTTCAC
CGCAGTATGACAATGGTTATGACGTCGCAGATTATCGTCAAATTGATCCACGCTTTGGGACCATGGCCGATTTTGACGAG
TTGGCCAAAAAACTTAAAGCGGCAGGTATCGACATCATGCTGGACATGGTGCTGAACCATACCAGCACAGAGCATGCTTG
GTTTCAAAAGGCTTTAGCAGGTGACAAACATTATCAGGCATACTATTACATTCGACCACCAAAGCCGGATGGCAGTTTGC
CAACAAATTGGGAAAGCAAGTTTGGCGGCCCAGCTTGGGCACCGTTTGGCGATACAGGCAATTATTATTTGCATTTATAT
GAACGGCGCCAAGCAGATTTGAATTGGCACAATCCAGCGGTTCGACAAGAAGCTGCTGCCATTATCAATTTTTGGCGAGC
AAAAGGTGTCCATGGTTTTCGGTTCGATGTTCTCAATGTTATTGGTAAAGCCGATAAGCTTGTTGATGCACCGCCAAGTG
TGGCCAGCAAAACGTTGTATACCGATACACCGATTGTTCAGGACTATTTGAAGGAGCTGGCAGCAAACAGCTTCGGTCAA
GATGATAATCGTGTGACGGTTGGCGAAATGAGTTCCACCACAATTGCCAATTCGATTGCTTATACCAAACCGGACAACCA
TGAACTTTCAATGTTTTTTCAATTCCATCATCTTAAAACAGACTACAAGAACGGTGAAAAGTGGAGCAAGGTGCCATATG
ATTTCAACGCCTTGCGCGATATTCTCCACACTTGGGGTCAGGGACTTGATCAAGGTGGTGGTTGGCAGGCACTGTTTTGG
AACAACCACGATCAACCGCGGGCCATCAATCGATTTGGCGATGTCGGGCAATATCGGGTTAAAAGCGCGGAATTGCTGGC
AGCAGCGATTCATTTGAGCCGCGGCACACCTTATATCTATATGGGCGAGGAGATTGGGATGACTGATCCTGATTACACCA
GCATGGCAGATTATGTGGATGTGGAAGCTAAGAATGCTTATGCAGCACTGCTGGGAAAAGGCATGTCTGAAAAAGAAGCA
TTCGGCATTATTTTGGCGAAAGCCCGAGATAATAGCCGAACGCCAATGCAATGGGATGCCTCGGGCCATGCAGGGTTTAC
CACTGGCACGCCTTGGTTGCGACCAACAAATCAAGCTGCAATTAATGTGCAGGCTGAGCTTGCACATGGTGAAATTTTTA
AATTTTATCAGCAGCTGATCGCATTGCGTAAACAGTATCCAGTGATCAGTGACGGTAGCTACACGCCGTTTGGAACTGAA
ATTGATCGGTTGTATGCCTATATAAGAACATATGGCACACAACAATTGCTGGTGCTGAATAATTTCAGCGACAAGACAAT
GACCGTACCGCTACCCGAAAAGTTTCAAACTGCAAAAGTATTAATCACGAACGAAGCTACATTGACGCCAACCGCAACCA
TGACATTGCCGCCATACGCGACGATTGGGTTATTGCAGAAAGCGTGA

Upstream 100 bases:

>100_bases
TAGAGCGTGAACAGGCCCGTATAGAAACCGGAGTATAAGCGGCCTTGAAAGCCCTTATGTTCAGCTCTCAAACTCAGCAT
TTTCAGGAAAGGGAGTCACC

Downstream 100 bases:

>100_bases
TTTGGCTGGTTCGCTAGAAGAAGGCACTTAAGACAAAGCGCAGCTGGGTTTTCGTGCCAGCAAGCGTGTTGATAAAAGGG
GGAACAAGAAATGGCAGATA

Product: alpha, alpha-phosphotrehalase

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 548; Mature: 547

Protein sequence:

>548_residues
MGFHNKVIYQLYPKSFYDSDGDGVGDLRGIIDKIDYLKSLHVDMIWFNPFFVSPQYDNGYDVADYRQIDPRFGTMADFDE
LAKKLKAAGIDIMLDMVLNHTSTEHAWFQKALAGDKHYQAYYYIRPPKPDGSLPTNWESKFGGPAWAPFGDTGNYYLHLY
ERRQADLNWHNPAVRQEAAAIINFWRAKGVHGFRFDVLNVIGKADKLVDAPPSVASKTLYTDTPIVQDYLKELAANSFGQ
DDNRVTVGEMSSTTIANSIAYTKPDNHELSMFFQFHHLKTDYKNGEKWSKVPYDFNALRDILHTWGQGLDQGGGWQALFW
NNHDQPRAINRFGDVGQYRVKSAELLAAAIHLSRGTPYIYMGEEIGMTDPDYTSMADYVDVEAKNAYAALLGKGMSEKEA
FGIILAKARDNSRTPMQWDASGHAGFTTGTPWLRPTNQAAINVQAELAHGEIFKFYQQLIALRKQYPVISDGSYTPFGTE
IDRLYAYIRTYGTQQLLVLNNFSDKTMTVPLPEKFQTAKVLITNEATLTPTATMTLPPYATIGLLQKA

Sequences:

>Translated_548_residues
MGFHNKVIYQLYPKSFYDSDGDGVGDLRGIIDKIDYLKSLHVDMIWFNPFFVSPQYDNGYDVADYRQIDPRFGTMADFDE
LAKKLKAAGIDIMLDMVLNHTSTEHAWFQKALAGDKHYQAYYYIRPPKPDGSLPTNWESKFGGPAWAPFGDTGNYYLHLY
ERRQADLNWHNPAVRQEAAAIINFWRAKGVHGFRFDVLNVIGKADKLVDAPPSVASKTLYTDTPIVQDYLKELAANSFGQ
DDNRVTVGEMSSTTIANSIAYTKPDNHELSMFFQFHHLKTDYKNGEKWSKVPYDFNALRDILHTWGQGLDQGGGWQALFW
NNHDQPRAINRFGDVGQYRVKSAELLAAAIHLSRGTPYIYMGEEIGMTDPDYTSMADYVDVEAKNAYAALLGKGMSEKEA
FGIILAKARDNSRTPMQWDASGHAGFTTGTPWLRPTNQAAINVQAELAHGEIFKFYQQLIALRKQYPVISDGSYTPFGTE
IDRLYAYIRTYGTQQLLVLNNFSDKTMTVPLPEKFQTAKVLITNEATLTPTATMTLPPYATIGLLQKA
>Mature_547_residues
GFHNKVIYQLYPKSFYDSDGDGVGDLRGIIDKIDYLKSLHVDMIWFNPFFVSPQYDNGYDVADYRQIDPRFGTMADFDEL
AKKLKAAGIDIMLDMVLNHTSTEHAWFQKALAGDKHYQAYYYIRPPKPDGSLPTNWESKFGGPAWAPFGDTGNYYLHLYE
RRQADLNWHNPAVRQEAAAIINFWRAKGVHGFRFDVLNVIGKADKLVDAPPSVASKTLYTDTPIVQDYLKELAANSFGQD
DNRVTVGEMSSTTIANSIAYTKPDNHELSMFFQFHHLKTDYKNGEKWSKVPYDFNALRDILHTWGQGLDQGGGWQALFWN
NHDQPRAINRFGDVGQYRVKSAELLAAAIHLSRGTPYIYMGEEIGMTDPDYTSMADYVDVEAKNAYAALLGKGMSEKEAF
GIILAKARDNSRTPMQWDASGHAGFTTGTPWLRPTNQAAINVQAELAHGEIFKFYQQLIALRKQYPVISDGSYTPFGTEI
DRLYAYIRTYGTQQLLVLNNFSDKTMTVPLPEKFQTAKVLITNEATLTPTATMTLPPYATIGLLQKA

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=557, Percent_Identity=29.2639138240575, Blast_Score=196, Evalue=6e-50,
Organism=Escherichia coli, GI1790687, Length=549, Percent_Identity=46.8123861566485, Blast_Score=488, Evalue=1e-139,
Organism=Escherichia coli, GI1786604, Length=186, Percent_Identity=30.1075268817204, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32565753, Length=194, Percent_Identity=31.4432989690722, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25147709, Length=525, Percent_Identity=24.7619047619048, Blast_Score=85, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6321726, Length=565, Percent_Identity=32.3893805309734, Blast_Score=275, Evalue=1e-74,
Organism=Saccharomyces cerevisiae, GI6322245, Length=568, Percent_Identity=30.2816901408451, Blast_Score=271, Evalue=2e-73,
Organism=Saccharomyces cerevisiae, GI6322241, Length=567, Percent_Identity=32.8042328042328, Blast_Score=270, Evalue=4e-73,
Organism=Saccharomyces cerevisiae, GI6322021, Length=567, Percent_Identity=32.8042328042328, Blast_Score=270, Evalue=4e-73,
Organism=Saccharomyces cerevisiae, GI6324416, Length=567, Percent_Identity=32.8042328042328, Blast_Score=270, Evalue=5e-73,
Organism=Saccharomyces cerevisiae, GI6321731, Length=562, Percent_Identity=32.0284697508897, Blast_Score=266, Evalue=4e-72,
Organism=Saccharomyces cerevisiae, GI6319776, Length=562, Percent_Identity=32.0284697508897, Blast_Score=266, Evalue=7e-72,
Organism=Drosophila melanogaster, GI45549022, Length=560, Percent_Identity=31.6071428571429, Blast_Score=238, Evalue=1e-62,
Organism=Drosophila melanogaster, GI24586591, Length=596, Percent_Identity=31.3758389261745, Blast_Score=235, Evalue=5e-62,
Organism=Drosophila melanogaster, GI24583745, Length=551, Percent_Identity=30.8529945553539, Blast_Score=229, Evalue=4e-60,
Organism=Drosophila melanogaster, GI221330053, Length=492, Percent_Identity=34.1463414634146, Blast_Score=229, Evalue=5e-60,
Organism=Drosophila melanogaster, GI24583749, Length=547, Percent_Identity=31.4442413162706, Blast_Score=228, Evalue=8e-60,
Organism=Drosophila melanogaster, GI24583747, Length=545, Percent_Identity=31.3761467889908, Blast_Score=228, Evalue=9e-60,
Organism=Drosophila melanogaster, GI24586597, Length=558, Percent_Identity=30.8243727598566, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24586589, Length=550, Percent_Identity=33.0909090909091, Blast_Score=221, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24586599, Length=557, Percent_Identity=29.9820466786355, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24586587, Length=521, Percent_Identity=30.9021113243762, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI24586593, Length=583, Percent_Identity=30.188679245283, Blast_Score=209, Evalue=5e-54,
Organism=Drosophila melanogaster, GI281360393, Length=529, Percent_Identity=28.3553875236295, Blast_Score=151, Evalue=9e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 61880; Mature: 61749

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFHNKVIYQLYPKSFYDSDGDGVGDLRGIIDKIDYLKSLHVDMIWFNPFFVSPQYDNGY
CCCCCCEEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECEEEECCCCCCCC
DVADYRQIDPRFGTMADFDELAKKLKAAGIDIMLDMVLNHTSTEHAWFQKALAGDKHYQA
CCCHHHCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEE
YYYIRPPKPDGSLPTNWESKFGGPAWAPFGDTGNYYLHLYERRQADLNWHNPAVRQEAAA
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHH
IINFWRAKGVHGFRFDVLNVIGKADKLVDAPPSVASKTLYTDTPIVQDYLKELAANSFGQ
HHHHHHHCCCCCHHHHHHHHHCCHHHHCCCCCCHHCCEEECCCHHHHHHHHHHHHCCCCC
DDNRVTVGEMSSTTIANSIAYTKPDNHELSMFFQFHHLKTDYKNGEKWSKVPYDFNALRD
CCCEEEECCCCCHHHHCCEEECCCCCCCEEEEEEEEHHHCCCCCCCCCCCCCCCHHHHHH
ILHTWGQGLDQGGGWQALFWNNHDQPRAINRFGDVGQYRVKSAELLAAAIHLSRGTPYIY
HHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEE
MGEEIGMTDPDYTSMADYVDVEAKNAYAALLGKGMSEKEAFGIILAKARDNSRTPMQWDA
ECCCCCCCCCCHHHHHHHEEEECCCHHHHHHCCCCCCCCEEEEEEEECCCCCCCCEEECC
SGHAGFTTGTPWLRPTNQAAINVQAELAHGEIFKFYQQLIALRKQYPVISDGSYTPFGTE
CCCCCCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHCCEECCCCCCCCCHH
IDRLYAYIRTYGTQQLLVLNNFSDKTMTVPLPEKFQTAKVLITNEATLTPTATMTLPPYA
HHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCCCEEEEEECCCEECCEEEEECCCCH
TIGLLQKA
HHHHHCCC
>Mature Secondary Structure 
GFHNKVIYQLYPKSFYDSDGDGVGDLRGIIDKIDYLKSLHVDMIWFNPFFVSPQYDNGY
CCCCCEEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECEEEECCCCCCCC
DVADYRQIDPRFGTMADFDELAKKLKAAGIDIMLDMVLNHTSTEHAWFQKALAGDKHYQA
CCCHHHCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEE
YYYIRPPKPDGSLPTNWESKFGGPAWAPFGDTGNYYLHLYERRQADLNWHNPAVRQEAAA
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHH
IINFWRAKGVHGFRFDVLNVIGKADKLVDAPPSVASKTLYTDTPIVQDYLKELAANSFGQ
HHHHHHHCCCCCHHHHHHHHHCCHHHHCCCCCCHHCCEEECCCHHHHHHHHHHHHCCCCC
DDNRVTVGEMSSTTIANSIAYTKPDNHELSMFFQFHHLKTDYKNGEKWSKVPYDFNALRD
CCCEEEECCCCCHHHHCCEEECCCCCCCEEEEEEEEHHHCCCCCCCCCCCCCCCHHHHHH
ILHTWGQGLDQGGGWQALFWNNHDQPRAINRFGDVGQYRVKSAELLAAAIHLSRGTPYIY
HHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEE
MGEEIGMTDPDYTSMADYVDVEAKNAYAALLGKGMSEKEAFGIILAKARDNSRTPMQWDA
ECCCCCCCCCCHHHHHHHEEEECCCHHHHHHCCCCCCCCEEEEEEEECCCCCCCCEEECC
SGHAGFTTGTPWLRPTNQAAINVQAELAHGEIFKFYQQLIALRKQYPVISDGSYTPFGTE
CCCCCCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHCCEECCCCCCCCCHH
IDRLYAYIRTYGTQQLLVLNNFSDKTMTVPLPEKFQTAKVLITNEATLTPTATMTLPPYA
HHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCCCEEEEEECCCEECCEEEEECCCCH
TIGLLQKA
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7651129; 8969503; 9384377; 7751281 [H]