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The map label for this gene is treR [H]

Identifier: 116494179

GI number: 116494179

Start: 623741

End: 624457

Strand: Direct

Name: treR [H]

Synonym: LSEI_0629

Alternate gene names: 116494179

Gene position: 623741-624457 (Clockwise)

Preceding gene: 116494178

Following gene: 116494180

Centisome position: 21.54

GC content: 47.7

Gene sequence:

>717_bases
ATGCGGAAGTATGATGTGATCTATCAGGATTTGAAAGATAAGATCGAGGCCGAAATTTATACGACTGGTTCATTATTGCC
GAGCGAGAATACGCTGCAGGATATGTATCAGGCATCGCGCGACACGGTACGTAAAGCTTTGCGGCTGCTCAAAGATGATG
GCTTCATTCAATCGCAGAAAGGCAGAGGATCAATCGTGATCAATCGCCAAGAATATGTCTTCCCAGTGTCAGGTGTCGTC
AGTTATGCCGAATTGGCTGAGCAGCTTCACTTGCAGACAAGAACCGTGGTGTTGGCCAATCATTTTGCCGCACTTCCGGC
CAAGTCCTTTAAAGATGTTGATCCGGATGTTGAAGTCAAGCAGATGCGTTTGCTGAAGCGAGTGCGTTACTTGGAAAAAG
AGCCGGATATCATTGATATCGATTATTTGGATCCAAGAGTCGTGCCGCCGATTCCGGAGTCGGTGGCAAGGGATTCGTTG
TATGCGTATCTCGAAGGACAAATTGGCTTGGAAATTGCTTATGCCACAAAAGAGATCACGGTTGAAACGGCAACTGAAGA
AGATCGTCGTTATCTAAATCTTCCTGAAGGTGCCATGGTTGTAGTTGTTCGCAGTTGCAGTAGTTTGGCAGACACTAGAA
AATTTCAATACACAGAGTCACGGCACCGGGCAGATCGCTTCAAGTTCCACGACTTCGCCCGGCGCGCACGACCATAG

Upstream 100 bases:

>100_bases
CGCGAAGTATTTAAAAGCGTTTAAACATTATTAGTTGACATACCTGTACGTACAGGTAAAATAAAGTTTGCAAGTGAAAG
CGATTTCTGGAGGAGAAGGC

Downstream 100 bases:

>100_bases
AGCGTGAACAGGCCCGTATAGAAACCGGAGTATAAGCGGCCTTGAAAGCCCTTATGTTCAGCTCTCAAACTCAGCATTTT
CAGGAAAGGGAGTCACCATG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MRKYDVIYQDLKDKIEAEIYTTGSLLPSENTLQDMYQASRDTVRKALRLLKDDGFIQSQKGRGSIVINRQEYVFPVSGVV
SYAELAEQLHLQTRTVVLANHFAALPAKSFKDVDPDVEVKQMRLLKRVRYLEKEPDIIDIDYLDPRVVPPIPESVARDSL
YAYLEGQIGLEIAYATKEITVETATEEDRRYLNLPEGAMVVVVRSCSSLADTRKFQYTESRHRADRFKFHDFARRARP

Sequences:

>Translated_238_residues
MRKYDVIYQDLKDKIEAEIYTTGSLLPSENTLQDMYQASRDTVRKALRLLKDDGFIQSQKGRGSIVINRQEYVFPVSGVV
SYAELAEQLHLQTRTVVLANHFAALPAKSFKDVDPDVEVKQMRLLKRVRYLEKEPDIIDIDYLDPRVVPPIPESVARDSL
YAYLEGQIGLEIAYATKEITVETATEEDRRYLNLPEGAMVVVVRSCSSLADTRKFQYTESRHRADRFKFHDFARRARP
>Mature_238_residues
MRKYDVIYQDLKDKIEAEIYTTGSLLPSENTLQDMYQASRDTVRKALRLLKDDGFIQSQKGRGSIVINRQEYVFPVSGVV
SYAELAEQLHLQTRTVVLANHFAALPAKSFKDVDPDVEVKQMRLLKRVRYLEKEPDIIDIDYLDPRVVPPIPESVARDSL
YAYLEGQIGLEIAYATKEITVETATEEDRRYLNLPEGAMVVVVRSCSSLADTRKFQYTESRHRADRFKFHDFARRARP

Specific function: Repressor for the trehalose operon (treP and treA). Binds trehalose-6-phosphate, which probably acts as an inducer [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=238, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87082252, Length=197, Percent_Identity=27.4111675126904, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR012770
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27451; Mature: 27451

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKYDVIYQDLKDKIEAEIYTTGSLLPSENTLQDMYQASRDTVRKALRLLKDDGFIQSQK
CCCHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCC
GRGSIVINRQEYVFPVSGVVSYAELAEQLHLQTRTVVLANHFAALPAKSFKDVDPDVEVK
CCCCEEEECCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
QMRLLKRVRYLEKEPDIIDIDYLDPRVVPPIPESVARDSLYAYLEGQIGLEIAYATKEIT
HHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHEEECCCCCEEEEEEEEEEE
VETATEEDRRYLNLPEGAMVVVVRSCSSLADTRKFQYTESRHRADRFKFHDFARRARP
EEECCCCCHHEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKYDVIYQDLKDKIEAEIYTTGSLLPSENTLQDMYQASRDTVRKALRLLKDDGFIQSQK
CCCHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCC
GRGSIVINRQEYVFPVSGVVSYAELAEQLHLQTRTVVLANHFAALPAKSFKDVDPDVEVK
CCCCEEEECCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
QMRLLKRVRYLEKEPDIIDIDYLDPRVVPPIPESVARDSLYAYLEGQIGLEIAYATKEIT
HHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHEEECCCCCEEEEEEEEEEE
VETATEEDRRYLNLPEGAMVVVVRSCSSLADTRKFQYTESRHRADRFKFHDFARRARP
EEECCCCCHHEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8917076; 8969503; 9384377; 7651129; 8755887 [H]