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The map label for this gene is ribD [H]

Identifier: 116493546

GI number: 116493546

Start: 1799813

End: 1800874

Strand: Reverse

Name: ribD [H]

Synonym: PEPE_1820

Alternate gene names: 116493546

Gene position: 1800874-1799813 (Counterclockwise)

Preceding gene: 116493552

Following gene: 116493545

Centisome position: 98.28

GC content: 40.3

Gene sequence:

>1062_bases
GTGATTTTGATTAGTGAACAAGATTATATGAATTTAGCTTTCGAAATGGCAGAGAAAGGGAAGTATCAAACGTGGACGAA
TCCTTTAGTGGGAGCGGTAATCGTTAAGAACAACGTGGTTTTAGCTAAAGGGTATCACCACCAGTTTGGAGCCGCTCATG
CTGAAATTGATGCTTTGCAGCACTTAGATGATCTAAAACAAGCTAGAGGTGCTACGATGTACGTCAGCCTAGAGCCGTGC
AGTCACTTTGGTAAGACGCCTCCTTGTGCTAAAAAGTTAGCTGAAGTAGGTATTAAAGCAGTTGTAGTTGGTCAAAAAGA
TCCGAATCCATTAGTCGCGGGTCGAGGACTTCAAATTTTAAGGGATGCTGGAATTGAAATAAAAGTTTTAAACCAAACTG
GAGGATTAAATGTTAAATACAATTTTTTCTATCAGCATCAGCGTCCGTATGTAAATGTAAAGTATGCCATGACTTTGGAT
GGAAAAATTAACCAGCAGGCCAACCAACGCAGCATTATTACTGGTAAAGAAGCCTATCAAGACAGCCAGCAATTACGGGC
AGAATATCAAGCAATTTTGGTTGGTGAAAACACATTAAAAGTTGATCATCCCCAATTAACAGTCCGCCAAATCGCTGTTT
ATCAGCAACCTTGGCGAATGGTTTTGATAAGAGATGTAGATCAACTTAAAGTCGAAGATTATGCGTTTTTTAAAACAGCA
GATCCAATCTTATTACTTACTTCATCCGTAACTCGACGACAGTGGCCGAATAACGTAGAAGTGATTTCTGATCGGTGGAC
CCCCAATAAAATCCTAACGCTACTGGCTAAACGAGGGATTCAAAGTGTTTTAGTTGAAGGTGGGAGTCAAATTCACGCCG
AGTTTTTAGCAAGCGGTCTGGTGGATGAAATTAATGTCTATCTTGCACCACGTATTTACGGAGCGACGGGGTTACCAGCG
ATATTTAACCCTACTCAATTACCATATCAATCGAATGCATATCAGTTAGTTGAAAAAATGGAATTGGGGCCAGATATGAA
ATTTAGACTGAGGAGAGTATAG

Upstream 100 bases:

>100_bases
CTCTTTTGTACGCTTTTTGGCGTACATGCTCGTATGGAGTCTTATTTAGCTATCAAAAATCATGCCCCGCACAAATTTTG
TGTGGGGCTTTTTTCGTGGG

Downstream 100 bases:

>100_bases
ATGTTTACTGGAATAATTAAAGCAAAAGGCATTATCAGCCAGATTAAACGCAATCAAGCAACCGCGCAAATTATGATTGC
CACACCGATGACCCACCAAA

Product: diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MILISEQDYMNLAFEMAEKGKYQTWTNPLVGAVIVKNNVVLAKGYHHQFGAAHAEIDALQHLDDLKQARGATMYVSLEPC
SHFGKTPPCAKKLAEVGIKAVVVGQKDPNPLVAGRGLQILRDAGIEIKVLNQTGGLNVKYNFFYQHQRPYVNVKYAMTLD
GKINQQANQRSIITGKEAYQDSQQLRAEYQAILVGENTLKVDHPQLTVRQIAVYQQPWRMVLIRDVDQLKVEDYAFFKTA
DPILLLTSSVTRRQWPNNVEVISDRWTPNKILTLLAKRGIQSVLVEGGSQIHAEFLASGLVDEINVYLAPRIYGATGLPA
IFNPTQLPYQSNAYQLVEKMELGPDMKFRLRRV

Sequences:

>Translated_353_residues
MILISEQDYMNLAFEMAEKGKYQTWTNPLVGAVIVKNNVVLAKGYHHQFGAAHAEIDALQHLDDLKQARGATMYVSLEPC
SHFGKTPPCAKKLAEVGIKAVVVGQKDPNPLVAGRGLQILRDAGIEIKVLNQTGGLNVKYNFFYQHQRPYVNVKYAMTLD
GKINQQANQRSIITGKEAYQDSQQLRAEYQAILVGENTLKVDHPQLTVRQIAVYQQPWRMVLIRDVDQLKVEDYAFFKTA
DPILLLTSSVTRRQWPNNVEVISDRWTPNKILTLLAKRGIQSVLVEGGSQIHAEFLASGLVDEINVYLAPRIYGATGLPA
IFNPTQLPYQSNAYQLVEKMELGPDMKFRLRRV
>Mature_353_residues
MILISEQDYMNLAFEMAEKGKYQTWTNPLVGAVIVKNNVVLAKGYHHQFGAAHAEIDALQHLDDLKQARGATMYVSLEPC
SHFGKTPPCAKKLAEVGIKAVVVGQKDPNPLVAGRGLQILRDAGIEIKVLNQTGGLNVKYNFFYQHQRPYVNVKYAMTLD
GKINQQANQRSIITGKEAYQDSQQLRAEYQAILVGENTLKVDHPQLTVRQIAVYQQPWRMVLIRDVDQLKVEDYAFFKTA
DPILLLTSSVTRRQWPNNVEVISDRWTPNKILTLLAKRGIQSVLVEGGSQIHAEFLASGLVDEINVYLAPRIYGATGLPA
IFNPTQLPYQSNAYQLVEKMELGPDMKFRLRRV

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=369, Percent_Identity=33.6043360433604, Blast_Score=191, Evalue=6e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 39746; Mature: 39746

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILISEQDYMNLAFEMAEKGKYQTWTNPLVGAVIVKNNVVLAKGYHHQFGAAHAEIDALQ
CEEECCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEEEECCCCCCCCHHHHHHHHH
HLDDLKQARGATMYVSLEPCSHFGKTPPCAKKLAEVGIKAVVVGQKDPNPLVAGRGLQIL
HHHHHHHHCCCEEEEEECCHHHCCCCCHHHHHHHHCCEEEEEEECCCCCCEEECCCHHHH
RDAGIEIKVLNQTGGLNVKYNFFYQHQRPYVNVKYAMTLDGKINQQANQRSIITGKEAYQ
HHCCCEEEEEECCCCCEEEEEEEEECCCCEEEEEEEEEECCCCCCCCCCCCEECCHHHHH
DSQQLRAEYQAILVGENTLKVDHPQLTVRQIAVYQQPWRMVLIRDVDQLKVEDYAFFKTA
HHHHHHHHEEEEEECCCEEEECCCCHHHHHHHHHHCCCEEEEEECCCHHEECCEEEEECC
DPILLLTSSVTRRQWPNNVEVISDRWTPNKILTLLAKRGIQSVLVEGGSQIHAEFLASGL
CCEEEEECCHHHHCCCCCCEEEECCCCHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHCC
VDEINVYLAPRIYGATGLPAIFNPTQLPYQSNAYQLVEKMELGPDMKFRLRRV
HHHCEEEEECEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEECC
>Mature Secondary Structure
MILISEQDYMNLAFEMAEKGKYQTWTNPLVGAVIVKNNVVLAKGYHHQFGAAHAEIDALQ
CEEECCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEEEECCCCCCCCHHHHHHHHH
HLDDLKQARGATMYVSLEPCSHFGKTPPCAKKLAEVGIKAVVVGQKDPNPLVAGRGLQIL
HHHHHHHHCCCEEEEEECCHHHCCCCCHHHHHHHHCCEEEEEEECCCCCCEEECCCHHHH
RDAGIEIKVLNQTGGLNVKYNFFYQHQRPYVNVKYAMTLDGKINQQANQRSIITGKEAYQ
HHCCCEEEEEECCCCCEEEEEEEEECCCCEEEEEEEEEECCCCCCCCCCCCEECCHHHHH
DSQQLRAEYQAILVGENTLKVDHPQLTVRQIAVYQQPWRMVLIRDVDQLKVEDYAFFKTA
HHHHHHHHEEEEEECCCEEEECCCCHHHHHHHHHHCCCEEEEEECCCHHEECCEEEEECC
DPILLLTSSVTRRQWPNNVEVISDRWTPNKILTLLAKRGIQSVLVEGGSQIHAEFLASGL
CCEEEEECCHHHHCCCCCCEEEECCCCHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHCC
VDEINVYLAPRIYGATGLPAIFNPTQLPYQSNAYQLVEKMELGPDMKFRLRRV
HHHCEEEEECEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9297088 [H]