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The map label for this gene is ribE [H]

Identifier: 116493545

GI number: 116493545

Start: 1799207

End: 1799812

Strand: Reverse

Name: ribE [H]

Synonym: PEPE_1819

Alternate gene names: 116493545

Gene position: 1799812-1799207 (Counterclockwise)

Preceding gene: 116493546

Following gene: 116493544

Centisome position: 98.22

GC content: 37.95

Gene sequence:

>606_bases
ATGTTTACTGGAATAATTAAAGCAAAAGGCATTATCAGCCAGATTAAACGCAATCAAGCAACCGCGCAAATTATGATTGC
CACACCGATGACCCACCAAATTCATAGCAAAATTGGAGATAGCATTGCCATCAATGGGATTTGTTTAACGATTACTAGCA
TTTTAAACGAAGGATTTACCGTCGAAGTAATGCCCGAAACAACCCATCGAACGAGCCTTGCGAATATGAAAGATGGAATG
GAGGTTAATCTAGAACCGGCTTTGCTAGCCACAGACCGCTTAGATGGTCATTTTGTTTTGGGACATGTAGATACAACGGC
CAAATTAGTTAACAGGATGTTAAATGAAAATTCAATCGTCCTAACCTTTGAAATTAATCCTGACTATATAGATTACGTGG
TCGAAAAGGGCTCGATCACCATCGATGGAGTGAGTTTAACGGTTTCAGCGGTGGAGAAGCAACTGTTTGAAGTTAGTTTG
ATTCCACATACCTTACAAGTAACCACGCTAGGTAATTTAAAGGCTAATGATGTTGTGAATGTTGAAACTGATATTTTAGG
AAAATACATTTTAAACGAAAATCGTGGTGTAAATAATGAAAAATAG

Upstream 100 bases:

>100_bases
ATTTAACCCTACTCAATTACCATATCAATCGAATGCATATCAGTTAGTTGAAAAAATGGAATTGGGGCCAGATATGAAAT
TTAGACTGAGGAGAGTATAG

Downstream 100 bases:

>100_bases
AATAATCGAAAAAATTGAAAATGCTCTACAAACTTTGAAAAATGGCGGCCTCATTATCATAACGGACGATGAAAATCGTG
AAAGTGAAGGAGACATGGTG

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MFTGIIKAKGIISQIKRNQATAQIMIATPMTHQIHSKIGDSIAINGICLTITSILNEGFTVEVMPETTHRTSLANMKDGM
EVNLEPALLATDRLDGHFVLGHVDTTAKLVNRMLNENSIVLTFEINPDYIDYVVEKGSITIDGVSLTVSAVEKQLFEVSL
IPHTLQVTTLGNLKANDVVNVETDILGKYILNENRGVNNEK

Sequences:

>Translated_201_residues
MFTGIIKAKGIISQIKRNQATAQIMIATPMTHQIHSKIGDSIAINGICLTITSILNEGFTVEVMPETTHRTSLANMKDGM
EVNLEPALLATDRLDGHFVLGHVDTTAKLVNRMLNENSIVLTFEINPDYIDYVVEKGSITIDGVSLTVSAVEKQLFEVSL
IPHTLQVTTLGNLKANDVVNVETDILGKYILNENRGVNNEK
>Mature_201_residues
MFTGIIKAKGIISQIKRNQATAQIMIATPMTHQIHSKIGDSIAINGICLTITSILNEGFTVEVMPETTHRTSLANMKDGM
EVNLEPALLATDRLDGHFVLGHVDTTAKLVNRMLNENSIVLTFEINPDYIDYVVEKGSITIDGVSLTVSAVEKQLFEVSL
IPHTLQVTTLGNLKANDVVNVETDILGKYILNENRGVNNEK

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=187, Percent_Identity=37.4331550802139, Blast_Score=106, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6319733, Length=201, Percent_Identity=38.8059701492537, Blast_Score=131, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22029; Mature: 22029

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIIKAKGIISQIKRNQATAQIMIATPMTHQIHSKIGDSIAINGICLTITSILNEGFT
CCCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHCCCCEEECHHHHHHHHHHCCCCE
VEVMPETTHRTSLANMKDGMEVNLEPALLATDRLDGHFVLGHVDTTAKLVNRMLNENSIV
EEEECCCCCHHHHHHCCCCCEEECCCEEEEECCCCCEEEEEECCHHHHHHHHHHCCCCEE
LTFEINPDYIDYVVEKGSITIDGVSLTVSAVEKQLFEVSLIPHTLQVTTLGNLKANDVVN
EEEEECCCCEEEEEECCCEEEECCEEEHHHHHHHHHEEEECCCEEEEEEECCCCCCCEEE
VETDILGKYILNENRGVNNEK
CHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MFTGIIKAKGIISQIKRNQATAQIMIATPMTHQIHSKIGDSIAINGICLTITSILNEGFT
CCCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHCCCCEEECHHHHHHHHHHCCCCE
VEVMPETTHRTSLANMKDGMEVNLEPALLATDRLDGHFVLGHVDTTAKLVNRMLNENSIV
EEEECCCCCHHHHHHCCCCCEEECCCEEEEECCCCCEEEEEECCHHHHHHHHHHCCCCEE
LTFEINPDYIDYVVEKGSITIDGVSLTVSAVEKQLFEVSLIPHTLQVTTLGNLKANDVVN
EEEEECCCCEEEEEECCCEEEECCEEEHHHHHHHHHEEEECCCEEEEEEECCCCCCCEEE
VETDILGKYILNENRGVNNEK
CHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]