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The map label for this gene is alsR [H]

Identifier: 116493527

GI number: 116493527

Start: 1778258

End: 1779139

Strand: Reverse

Name: alsR [H]

Synonym: PEPE_1800

Alternate gene names: 116493527

Gene position: 1779139-1778258 (Counterclockwise)

Preceding gene: 116493528

Following gene: 116493526

Centisome position: 97.09

GC content: 36.17

Gene sequence:

>882_bases
ATGTTTCAACAAATGCAGTATTTTATTGATGTGGTCGATGCACACAGTTTTACCCAAGCAGCTGCTGACGATAATATTTC
TCAATCGGCTATTTCCCAACAAATTAAAGAACTTGAAAATAATCTAGGAGTTTTATTGTTGAAACGTCAGGGTCGGAGCT
TCGAAATTACCCCAGCTGGACAGTACTTTTATCAGCATAGTAGGGATGTTTTAGGACAGGTTAAAAAAATTGTTAAAGAT
ACCGTTAGAATTGCCAATGATAACGAACCTGAATTAAGAGTTGGATATTTGAAAAGTTTTGGAACAACGGAGTTCTTACA
AACCGTTGCTGAATTTTCTAAATCTTACCCAGAAGTAAAAATTAAAATCAATAATGGAACGCATGAACAATTGTATGATT
GGTTGCGTGAAGAAAAAATTGATCTGGCTTTTTCTGATCAACGGCGAGCCCCTTCCAATGAATATGTAAATGATTTTTTG
ACAGAAAGTGGATTGATGGTTGCAGTAAGTCAAACGGGGGAATTTAGCCACGCAGAGCAAATTGATGTGGCTGATTTAGC
TGACTTGCCATGTATTTTAATTACCGATTCAAAGCAACAACTGGCAGAGGAAACATATTATCAAGAAATTTTAGGTGTTA
AAGGTGGTTTTCGATTAGTTGCTAACTACGATGAAGCCCAGATGCTGATTGCAGCTAATCAAGGATATTTAATTGTTAAT
CAGCGAACCCAAAACCTACTCGATAGTGGAATCATTCAAACCGTACCTTTGCACAATGGTGGGCATGAATTGACTCAGAA
GTATTATATGTACTGGAAAGTCGATAATTCAGGGTTTTATATTGAAACTTTTGCCGAAATGTTTGAGCATCATTTTAAAT
AA

Upstream 100 bases:

>100_bases
GAATTAACACCCCTCAATGATTATATTTAAGGAAGAGTTGAAATTTATTTCAGCTCTTTTTGTTTTATAATGAGGTAAAT
CCATGAAGTGAGGTAAACTA

Downstream 100 bases:

>100_bases
GTTTTACTTATTTAATAGAGTTAAGATTAGAATAGCTCGGCTCCTTAATTATAGATACCATATAGGATAGAAAGATATCA
AAGGAGTAAATCTATGACAA

Product: hypothetical protein

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MFQQMQYFIDVVDAHSFTQAAADDNISQSAISQQIKELENNLGVLLLKRQGRSFEITPAGQYFYQHSRDVLGQVKKIVKD
TVRIANDNEPELRVGYLKSFGTTEFLQTVAEFSKSYPEVKIKINNGTHEQLYDWLREEKIDLAFSDQRRAPSNEYVNDFL
TESGLMVAVSQTGEFSHAEQIDVADLADLPCILITDSKQQLAEETYYQEILGVKGGFRLVANYDEAQMLIAANQGYLIVN
QRTQNLLDSGIIQTVPLHNGGHELTQKYYMYWKVDNSGFYIETFAEMFEHHFK

Sequences:

>Translated_293_residues
MFQQMQYFIDVVDAHSFTQAAADDNISQSAISQQIKELENNLGVLLLKRQGRSFEITPAGQYFYQHSRDVLGQVKKIVKD
TVRIANDNEPELRVGYLKSFGTTEFLQTVAEFSKSYPEVKIKINNGTHEQLYDWLREEKIDLAFSDQRRAPSNEYVNDFL
TESGLMVAVSQTGEFSHAEQIDVADLADLPCILITDSKQQLAEETYYQEILGVKGGFRLVANYDEAQMLIAANQGYLIVN
QRTQNLLDSGIIQTVPLHNGGHELTQKYYMYWKVDNSGFYIETFAEMFEHHFK
>Mature_293_residues
MFQQMQYFIDVVDAHSFTQAAADDNISQSAISQQIKELENNLGVLLLKRQGRSFEITPAGQYFYQHSRDVLGQVKKIVKD
TVRIANDNEPELRVGYLKSFGTTEFLQTVAEFSKSYPEVKIKINNGTHEQLYDWLREEKIDLAFSDQRRAPSNEYVNDFL
TESGLMVAVSQTGEFSHAEQIDVADLADLPCILITDSKQQLAEETYYQEILGVKGGFRLVANYDEAQMLIAANQGYLIVN
QRTQNLLDSGIIQTVPLHNGGHELTQKYYMYWKVDNSGFYIETFAEMFEHHFK

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=200, Percent_Identity=31, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787879, Length=196, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789440, Length=173, Percent_Identity=26.5895953757225, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787806, Length=190, Percent_Identity=26.8421052631579, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790399, Length=198, Percent_Identity=23.2323232323232, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788748, Length=143, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1788887, Length=186, Percent_Identity=25.8064516129032, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787601, Length=148, Percent_Identity=25.6756756756757, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788297, Length=148, Percent_Identity=31.0810810810811, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789639, Length=125, Percent_Identity=32, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI145693193, Length=133, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI2367136, Length=184, Percent_Identity=24.4565217391304, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788481, Length=192, Percent_Identity=23.4375, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33568; Mature: 33568

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQQMQYFIDVVDAHSFTQAAADDNISQSAISQQIKELENNLGVLLLKRQGRSFEITPAG
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCEEEECCCH
QYFYQHSRDVLGQVKKIVKDTVRIANDNEPELRVGYLKSFGTTEFLQTVAEFSKSYPEVK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHCCHHHHHHHHHHHHCCCCEEE
IKINNGTHEQLYDWLREEKIDLAFSDQRRAPSNEYVNDFLTESGLMVAVSQTGEFSHAEQ
EEECCCCHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCC
IDVADLADLPCILITDSKQQLAEETYYQEILGVKGGFRLVANYDEAQMLIAANQGYLIVN
CCHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCEEEEE
QRTQNLLDSGIIQTVPLHNGGHELTQKYYMYWKVDNSGFYIETFAEMFEHHFK
CHHHHHHHCCCEEEECCCCCCHHHCEEEEEEEEECCCCEEHHHHHHHHHHHCC
>Mature Secondary Structure
MFQQMQYFIDVVDAHSFTQAAADDNISQSAISQQIKELENNLGVLLLKRQGRSFEITPAG
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCEEEECCCH
QYFYQHSRDVLGQVKKIVKDTVRIANDNEPELRVGYLKSFGTTEFLQTVAEFSKSYPEVK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHCCHHHHHHHHHHHHCCCCEEE
IKINNGTHEQLYDWLREEKIDLAFSDQRRAPSNEYVNDFLTESGLMVAVSQTGEFSHAEQ
EEECCCCHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCC
IDVADLADLPCILITDSKQQLAEETYYQEILGVKGGFRLVANYDEAQMLIAANQGYLIVN
CCHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCEEEEE
QRTQNLLDSGIIQTVPLHNGGHELTQKYYMYWKVDNSGFYIETFAEMFEHHFK
CHHHHHHHCCCEEEECCCCCCHHHCEEEEEEEEECCCCEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]